No abstract available.
Granuloma, Foreign-Body*

No abstract available.
Dermatitis, Contact*

No abstract available.
Cough* ; Humans ; Sarcoidosis* ; Skin*

No abstract available.

No abstract available.
Dermatitis, Atopic* ; Education* ; Pilot Projects*

Incontinentia pigmenti (IP) is an uncommon X-linked, dominantly inherited disorder due to a mutation in the NEMO (NF-kappaB essential modulator) gene on the X chromosome. IP mostly occurs in female infants, it is usually embryonic lethal in males. The mechanisms for survival of affected males are explained by the presence of an extra X chromosome (Klinefelter's syndrome), hypomorphic mutations, and somatic mosaicism. We report here a rare case of incontinentia pigmenti in a 13-year-old boy with Klinefelter's syndrome, NEMO gene mutation, and whorled, hyperkeratotic, hyperpigmented, linear lesions along the lines of Blaschko on the trunk and leg.
Adolescent ; Female ; Humans ; Incontinentia Pigmenti* ; Infant ; Klinefelter Syndrome* ; Leg ; Male ; Mosaicism ; X Chromosome

Pseudomonas infections can occur from inadequate chemical treatment of water, prolonged exposure to the water source and excessive numbers of bathers in the pool or hot tub. Therefore, pseudomonas folliculitis is also called 'hot tub folliculitis'. We report a 3-year-old boy with Pseudomonas aeruginosa folliculitis suggestively caused by water from the bathing tub of a Hotel. According to the sanitary code of the United States of America, pool staff should regularly check both chlorine and pH levels to prevent swimmers from recreational water infection. However, in Korea, there is no definite regulation regarding chlorine or pH level of recreational water. Thus, we report this issue with a review of the literature.
Americas ; Baths ; Chlorine ; Folliculitis ; Hydrogen-Ion Concentration ; Korea ; Preschool Child ; Pseudomonas ; Pseudomonas aeruginosa ; Pseudomonas Infections ; United States ; Water

No abstract available.
Diagnosis* ; Tinea*

Various functional activities have been reported for the fermented soybean products doenjang (DJ) and cheonggukjang (CGJ), although no systemic investigations of their immune functions have been conducted to date. We examined the effects of an experimental diet of DJ, CGJ, or a mixture of unfermented raw material for 4 weeks on overall immunity and immune safety in mice. No significant alterations were observed in peripheral or splenic immune cells among groups. Enhanced splenic natural killer cell activity was observed in the DJ and CGJ groups compared with the plain diet group. T helper type-1 (Th1)-mediated immune responses were enhanced in the DJ and CGJ groups with an upregulated production ratio of IFN-γ vs. IL-4 and IgG2a vs. IgG1 in stimulated splenic T and B cells, respectively. Resistance to Listeria monocytogenes infection was observed in the DJ and CGJ groups. Overall, the results of this study suggest that DJ and CGJ intake consolidates humoral and cellular immunity to Th1 responses.
Animals ; B-Lymphocytes ; Diet ; Immunity, Cellular ; Immunoglobulin G ; Interleukin-4 ; Killer Cells, Natural ; Listeria monocytogenes ; Mice* ; Soybeans*

Neonatal lupus is a rare rheumatic disease. Clinical manifestations include characteristic annular or macular rashes, congenital heart block, cytopenias, and hepatitis. Neonatal lupus is caused by transmission of maternal immunoglobulin G autoantibodies such as anti-SSA/Ro antibody or anti-SSB/La antibody to the fetus through the placenta. We report two cases of neonatal lupus. The first case refers to an 18-day-old male with annular rashes on both cheeks, neutropenia, positive tests for antinuclear antibody, anti-SSA/Ro antibody, and anti-SSB/La antibody. His mother was diagnosed with systemic lupus erythematosus characterized by positive tests for antinuclear antibody, anti-SSA/Ro antibody, and anti-SSB/La antibody. The second case represents a 32-day-old female with annular rash on both hands, soles, and the genital area, neutropenia, hepatitis, positive tests for antinuclear antibody, and anti-SSA/Ro antibody. Skin punch biopsy was conducted. Her mother did not have history of connective tissue diseases. We referred her mother to the division of rheumatology of the department of internal medicine. The mother was suspected with primary Sjögren's syndrome because of arthralgia and dry eye symptoms with positive tests for antinuclear antibody, anti-SSA/Ro antibody, anti-SSB/La antibody, and rheumatoid factor. It is necessary to suspect neonatal lupus in neonates or infants with characteristic annular rash with or without maternal history of connective tissue disorders.
Antibodies, Antinuclear ; Arthralgia ; Autoantibodies ; Biopsy ; Cheek ; Connective Tissue ; Connective Tissue Diseases ; Exanthema ; Female ; Fetus ; Hand ; Heart Block ; Hepatitis ; Humans ; Immunoglobulin G ; Infant ; Infant, Newborn ; Internal Medicine ; Lupus Erythematosus, Systemic ; Male ; Mothers ; Neutropenia ; Placenta ; Rheumatic Diseases ; Rheumatoid Factor ; Rheumatology ; Skin