BACKGROUND AND OBJECTIVE: The aim of this study was to compare the residual diameter stenosis after PTCA with fractional flow reserve (FFR) and coronary flow reserve (CFR), and investigate the correlation between FFR and CFR in patients with acute myocardial infarction (AMI). MATERIALS AND METHOD: The study population consisted of twenty seven patients with myocardial infarction. Baseline and hyperemic average peak velocity (APV) were measured using Doppler wire 15 minutes after restoration of infarct-related artery (IRA). CFR was obtained by the ratio of distal hyperemic APV to baseline APV. Distal coronary arterial pressure (Pd) was measured with advancing the wire distal to the lesion of IRA. Simultaneous proximal aortic pressure (Pa) was measured using guiding catheter. Myocardial FFR was obtained by the ratio of hyperemic Pd to hyperemic Pa. RESULTS: Post-interventional CFR and FFR were 0.85+/-0.44, 0.91+/-0.09. CFR did not show significant correlation with luminal diameter stenosis (%ST). There was no significant correlation between FFR and CFR with a correlation coefficient of 0.29 (p=.25). But, significant correlation was found between %ST and FFR, %ST and hyperemic PG (hPG) with correlation coefficient of -0.70 (p=.0012) and 0.68 (p=.0018). CONCLUSION: In AMI patients, %ST has a significant correlation with FFR and hPG after PTCA. But, there was no significant correlation between FFR and CFR.
Arterial Pressure ; Arteries ; Catheters ; Constriction, Pathologic ; Humans ; Myocardial Infarction* ; Phenobarbital

No abstract available.
Thrombocythemia, Essential*

Angioleiomyoma (AL) is a very rare benign tumor that originates from smooth muscle cells and has thick walled vessels. It may be found throughout the body but more frequently occurs in the lower extremities and rarely develops in the head and other parts of the body. This paper presents a case report of giant AL detected in a 33-year-old woman who complained of severe anemia, menorrhagia, and palpable lower abdominal mass. The patient underwent myomectomy and was diagnosed with AL based on the pathological report of mass. The effective treatment for AL is either simple hysterectomy or angiomyomectomy depending on the patient's desire to preserve fertility and symptom.
Adult ; Anemia ; Angiomyoma* ; Female ; Fertility ; Head ; Humans ; Hysterectomy ; Immunohistochemistry ; Leiomyoma ; Lower Extremity ; Menorrhagia ; Myocytes, Smooth Muscle ; Uterus*

OBJECTIVES: Even though experimental studies have suggested that iron can be involved in generating oxidative stress, epidemiologic studies on the association of markers of body iron stores with cardiovascular disease or cancer remain controversial. This study was performed to examine the association of serum ferritin and transferrin saturation (%TS) with all-cause, cancer, and cardiovascular mortality. METHODS: The study subjects were men aged 50 years or older and postmenopausal women of the Third National Health and Nutrition Examination Survey 1988-1994. Participants were followed-up for mortality through December 31, 2006. RESULTS: Serum ferritin was not associated with all-cause, cancer, or cardiovascular mortality for either men or postmenopausal women. However, all-cause, cancer, and cardiovascular mortality were inversely associated with %TS in men. Compared with men in the lowest quintile, adjusted hazard ratios for all-cause, cancer, and cardiovascular mortality were 0.85, 0.86, 0.76, and 0.74 (p for trend < 0.01), 0.82, 0.73, 0.75, and 0.63 (p for trend < 0.01), and 0.86, 0.81, 0.72, and 0.76 (p for trend < 0.01), respectively. For postmenopausal women, inverse associations were also observed for all-cause and cardiovascular mortality, but cancer mortality showed the significantly lower mortality only in the 2nd quintile of %TS compared with that of the 1st quintile. CONCLUSIONS: Unlike speculation on the role of iron from experimental studies, %TS was inversely associated with all-cause, cancer and cardiovascular mortality in men and postmenopausal women. On the other hand, serum ferritin was not associated with all-cause, cancer, or cardiovascular mortality.
Aged ; Cardiovascular Diseases/blood/*mortality ; Cause of Death ; Female ; Ferritins/*blood ; Follow-Up Studies ; Health Surveys ; Humans ; Male ; Middle Aged ; Neoplasms/*mortality ; Republic of Korea/epidemiology ; Transferrins/*blood

Objectives: This study aimed to assess hand grip strength and femoral neck bone mineral density levels among Korean fishery workers and investigate their association. Methods: Hand grip strength and femoral neck bone mineral density were measured in a survey and health examination conducted in 2021 among fishery workers in a southern region of South Korea. Covariates including gender, age, education level, income level, smoking behavior, drinking behavior, family history of hip fractures, use of calcium and vitamin D supplements, hypertension, diabetes, regular exercise, and body mass index were investigated. Multiple regression analysis was employed to assess the association between hand grip strength and femoral neck bone mineral density. Results: Among 147 fishery workers, 8.16% exhibited low hand grip strength levels indicative of possible sarcopenia, and a significant association was found between low hand grip strength and decreased femoral neck bone mineral density (β = -89.14, 95% CI = -160.50, -17.78). Additionally, factors such as women gender, advanced age, family history of hip fractures, and a body mass index below 25 kg/m 2 were associated with decreased femoral neck bone mineral density. In the subgroup analysis by gender, a correlation between low hand grip strength and decreased femoral neck bone mineral density was observed only in men. Conclusions Further research is needed to explore various determinants and intervention strategies to prevent musculoskeletal disorders among fishery workers, ultimately enhancing their quality of life and well-being.

The nucleoprotein (N) and glycoprotein (G) of 11 Korean rabies virus (RABV) isolates collected from animals diagnosed with rabies between 2008 and 2009 were subjected to molecular and phylogenetic analyses. Six isolates originated from domestic animals (cattle and dogs) and five were obtained from wild free-ranging raccoon dogs. The similarities in the nucleotide sequences of the N gene among all Korean isolates ranged from 98.1 to 99.8%, while those of the G gene ranged from 97.9 to 99.3%. Based on the nucleotide analysis of the N and G genes, the Korean RABV isolates were confirmed as genotype I of Lyssavirus and classified into four distinct subgroups with high similarity. Phylogenetic analysis showed that the Korean isolates were most closely related to the non-Korean NeiMeng1025B and 857r strains, which were isolated from rabid raccoon dogs in Eastern China and Russia, respectively. These findings suggest that the Korean RABV isolates originated from a rabid raccoon dog in Northeastern Asia. Genetic analysis of the Korean RABV isolates revealed no substitutions at several antigenic sites, indicating that the isolates circulating in Korea may be pathogenic in several hosts.
Animals ; Base Sequence ; Cattle ; Cattle Diseases/epidemiology/virology ; China ; Dog Diseases/epidemiology/virology ; Dogs ; Glycoproteins/genetics ; Molecular Sequence Data ; Nucleoproteins/genetics ; Phylogeny ; Rabies/*veterinary ; Rabies virus/classification/*genetics/pathogenicity ; Raccoon Dogs/*virology ; Republic of Korea ; Russia ; Sequence Analysis, DNA ; Sequence Homology, Nucleic Acid

BACKGROUND: Sedentary behavior has been shown to have deleterious effects on cardiovascular outcomes. This study aimed to examine the association between sedentary time and cardiovascular risk factors in Korean adults. METHODS: A cross-sectional study was performed using data from adults aged 19 years and above in the 2013 Korean National Health and Nutrition Examination Survey. Sedentary time was self-reported and categorized into quintiles. Cardiovascular risk factors, including blood pressure (BP), total cholesterol, high-density lipoprotein (HDL) cholesterol, triglycerides, low-density lipoprotein cholesterol, and fasting glucose levels, were categorized into dichotomous variables according to the Adult Treatment Panel III criteria. Multivariate logistic regression was performed with adjustment for various demographic and lifestyle variables, body mass index (BMI), waist circumference (WC), and moderate-to-vigorous physical activity. Complex sampling design was used, and survey weights and sample design variables were applied in analyses. RESULTS: A total of 3,301 individuals were included in the analyses, and mean sedentary time was 6.1 h/d. Prolonged sedentary time was significantly associated with high diastolic BP (top vs. bottom quintile: adjusted odds ratio [OR], 1.71; 95% confidence interval [CI], 1.09–2.68; Ptrend=0.03) and low HDL cholesterol level (top vs. bottom quintile: adjusted OR, 1.42; 95% CI, 1.02–1.98; Ptrend=0.02) after adjustment for BMI, WC, moderate-to-vigorous physical activity, and other variables. No significant associations were found between sedentary time and other cardiovascular risk factors. CONCLUSION: Prolonged sedentary time was significantly associated with high diastolic BP and low HDL cholesterol level in Korean adults. The associations were independent of general and abdominal obesity and moderate-to-vigorous physical activities.
Adult ; Blood Pressure ; Body Mass Index ; Cardiovascular Diseases ; Cholesterol ; Cholesterol, HDL ; Cross-Sectional Studies ; Fasting ; Glucose ; Humans ; Life Style ; Lipoproteins ; Logistic Models ; Motor Activity ; Nutrition Surveys ; Obesity, Abdominal ; Odds Ratio ; Risk Factors ; Sedentary Lifestyle ; Triglycerides ; Waist Circumference ; Weights and Measures

Porto-mesenteric venous thrombosis is a rare disorder, which can occur as a complication of many diseases. Porto-mesenteric venous thrombosis leads to venous hypertension, outpouring of blood into the bowel lumen and mesentery, distension and rupture of venules, and hemorrhgae and edema of the bowel wall. In cases of mild porto-mesenteric venous thrombosis, nonoperative management-consisting of fluid resuscitation, anticoagulation, and thrombolysis-may be acceptable in clinically stable patients with early diagnosis. If patients show clinical signs of peritonitis or deteriorates on medical management, prompt surgical intervention is warranted. At laparotomy, segmental resection of the involved bowel with primary anastomosis is easily accomplished, because the hemorrhagic infarction associated with porto-mesenteric venous thrombosis is limited. The optimal duration of anticoagulation therapy has not been defined. However, recommendation is that anticoagulation should be continued indefinitely, as it reduces the incidence of porto-mesenteric venous thrombosis recurrence. The patient in our study presented with a severely edematous duodenum and proximal jejunum in CT scan with signs of peritonitis due to perforation of the upper-jejunum. We had performed a percutaneous drainage for intraabdominal abscess which occurred the jejunal infarction. About 1 month later, a resection of a well-controlled fistula tract was done.
Abscess ; Drainage ; Duodenum ; Early Diagnosis ; Edema ; Fistula ; Humans ; Hypertension ; Incidence ; Infarction ; Jejunum ; Laparotomy ; Mesentery ; Peritonitis ; Recurrence ; Resuscitation ; Rupture ; Tomography, X-Ray Computed ; Venous Thrombosis* ; Venules

PURPOSE: Metastasis of a colorectal carcinoma to regional lymph nodes indicates poor prognosis. The detection of lymph node metastasis is routinely performed by his topathological analysis of hematoxylin-eosin (H&E) stained sections. However the routine histological technique may fail to detect isolated tumor cells in lymph nodes. The aims of this study are to elucidate the prognostic significance of the presence of isolated tumor cells in the regional lymph nodes in colorectal cancer, and to elucidate the correlation between the presence of isolated tumor cells and p53 protein expression in the primary colorectal cancer tissue. METHODS: We used immunohistochemical staining with anti-cytokeratin antibody to examine 452 lymph nodes in 24 patients (11 recurrent and 13 nonrecurrent) who were histologically determined Astler-Coller B. And we used immunohistochemical staining with p53 protein to examine primary colorectal cancer tissues of the patients. RESULTS: Immunohistochemical staining of cytokeratin revealed the presence of isolated tumor cells in 5/13 patients (38.5%), 5/214 lymph nodes (2.34%) in the nonrecurrent group and 6/11 patients (54.6%), 11/244 lymph nodes (4.51%) in the recurrent group, respectively. The detection rate of isolated tumor cells in the recurrent group was slightly higher than nonrecurrent group, but the difference was not significant statistically. The expression rate of p53 protein was 23.1% (3/13) in the nonrecurrent group and 36.4% (4/11) in the recurrent group, respectively. The expression rate of the p53 protein was not significantly correlated with the presence of isolated tumor cells in regional lymph nodes and the rate of tumor recurrence. CONCLUSIONS: The presence of isolated tumor cells in regional lymph nodes was not a prognostic indicator in predicting recurrence in histologically determined Astler- Collar B colorectal cancer patients.
Colorectal Neoplasms* ; Histological Techniques ; Humans ; Keratins ; Lymph Nodes* ; Neoplasm Metastasis ; Prognosis ; Recurrence

PURPOSE: We prospectively compared the treatment outcomes of photoselective vaporization of the prostate (PVP) with those of the gold standard transurethral resection of the prostate (TURP). MATERIALS AND METHODS: Between October 2004 and April 2006, a prospective clinical trial was performed with 131 and 41 patients treated by PVP and TURP, respectively. The efficacy of the two procedures were compared in terms of the International Prostate Symptom Score, quality of life score, peak urinary flow rate, postvoid residual volume, complications and perioperative outcomes at 1, 3, 6 and 12 months following treatment. RESULTS: The baseline characteristics of the two groups were similar. The operative times, catheter indwelling times and hospital stays were significantly shorter in the PVP group. All efficacy parameters were significantly improved in both groups compared to those obtained preoperatively. In addition, the degrees of improvement in the efficacy parameters were similar between the two groups within 12 months. With respect to the prostatic volume reduction, the difference between the pre- and post-PVP volumes during the study period was less than that of the TURP group (p<0.001). There were no differences in the overall complications between the two groups, with the exception of more common bleeding reguiring a transfusion and capsule perforation in the TURP group. CONCLUSIONS: PVP provides excellent intraoperative and postoperative safety, and facilitates immediate relief from obstructive voiding symptoms; similarly to TURP, but has the advantages of shorter hospital stays and catheter indwelling times. The short-term treatment outcomes 12 months after PVP and TURP were comparable, with the exception of the prostatic volume reduction.
Catheters ; Hemorrhage ; Humans ; Laser Therapy ; Length of Stay ; Operative Time ; Prospective Studies ; Prostate* ; Prostatic Hyperplasia* ; Quality of Life ; Residual Volume ; Transurethral Resection of Prostate ; Volatilization*