Search Results

Background: Despite the autologous serum skin test (ASST)and autologous plasma skin test (APST) is widely used test accessingwhether a patient with chronic spontaneous urticaria(CSU) has autoreactivity or not, the clinician often encounterdifficulty making correlation between the test result and clinicalimplications. Objective: This study was aimed to findany clinical and laboratory findings related to the ASST andAPST response. Agreement and correlation between the twotests was also analyzed. Methods: A retrospective study wasconducted on 300 CSU patients who underwent ASST, APST.The subjects were divided into four groups according to theskin test result. Also, the degree of serum and plasma responsewas recorded. Results: Both ASST and APST positivegroup had shorter duration of the disease, higher incidenceof at least one episode of angioedema than negative group.There were no significant differences in the positivity for autoantibodiesincluding antinuclear, ds-DNA, and thyroid-relatedbetween the two groups. The predicted positive rate ofASST and APST according to age showed bimodal peak and decreasing pattern according to disease duration. Predictedpositivity of both tests declined with increase in total immunoglobulineE (IgE) level. In the correlation study, the twotests showed high correlation coefficients. Conclusion ASSTand APST positivity may be related to disease duration andseverity of CSU. The two tests showed a generally consistentresult. Autoreactivity may be gradually lost as disease continues.We suggest the autoreactivity in CSU could arise independentlyfrom IgE mediated immune process.

1.Cerebrotendinous Xanthomatosis with Low Signal on Gradient Echo Magnetic Resonance Imaging.

2.Cerebrotendinous Xanthomatosis with Low Signal on Gradient Echo Magnetic Resonance Imaging.

3.Fronto-Ethmoidal Mucocele with Diplopia in Myasthenia Gravis Patient.

4.Fronto-Ethmoidal Mucocele with Diplopia in Myasthenia Gravis Patient.

5.Tolosa-Hunt Syndrome with Contralateral Diffuse Pachymeningeal and Soft Tissue Enhancement.

6.Tolosa-Hunt Syndrome with Contralateral Diffuse Pachymeningeal and Soft Tissue Enhancement.

7.The Relation of Autologous Serum Skin Test andAutologous Plasma Skin Test Result with VariousClinical and Laboratory Findings in Patients withChronic Spontaneous Urticaria

8.Onychomadesis Following Hand-foot-mouth Disease: A Report of Five Children.

9.A Case of Malignant Melanoma with Pseudoepitheliomatous Hyperplasia on the Sole.

10.Primary Cutaneous Adenoid Cystic Carcinoma of the Knee in a Young Male.

Display Mode

Output Records

File Type