We report a case of 53-year-old woman with personification following right middle cerebral artery territory infarction. Although she knew that her paralyzed left limbs belonged to her, she behaved as if it is a separate person. Verbalization of hatred toward her left arm was frequently observed. She attributed her neurologic deficit to the left arm instead of herself, frequently complaining in a fashion that 'I(a person except for the left arm) am all right but he/she(left arm) is wrong'. This delusional beliefs were mainly confined to her paralysed left limb, and were accompanied by left spatial neglect, transient anosognosia for hemiplegia and right-left disorientation.
Agnosia ; Arm ; Delusions ; Extremities* ; Female ; Hemiplegia ; Humans ; Infarction ; Middle Aged ; Middle Cerebral Artery ; Neurologic Manifestations ; Stroke*

No Abstract Available.
Tinea Capitis* ; Trichophyton*

Contact urticaria refers to a wheal-and-flare response after cutaneous exposure to certain chemicals. If contact urticaria is accompanied by systemic symptoms, it is referred to as contact urticaria syndrome. Herein we report two cases of contact urticaria syndrome occur-ring in nurses due to occupational exposure to cefotiam.
Cefotiam ; Occupational Exposure ; Urticaria*

Glassy cell carcinoma is a histologic subtype of cervical cancer with distinct pathologic features and it has an aggressive biologic course. It was first described by Glucksmann and Cherry in 1956 as a poorly differentiated adenoquamous carcinoma and commented on its poor prognosis, unresponsiveness to traditional modes of therapy, and often associated with pregnancy. The characteristic histologic features are defined as follows: 1) cells with a moderate amount of cytoplasm resembling ground glass, 2) a fairly distinct cell membrane that stains with eosin or PAS, 3) large nuclei with prominent nucleoli. We present two cases of glassy cell carcinoma of the cervix successfullyl treated by neoadjuvant chemotherapy and radical hyterectorny, with a brief review of literatures.
Cell Membrane ; Cervix Uteri* ; Coloring Agents ; Cytoplasm ; Drug Therapy* ; Eosine Yellowish-(YS) ; Female ; Glass ; Hysterectomy* ; Pregnancy ; Prognosis ; Prunus ; Uterine Cervical Neoplasms

BACKGROUND & PURPOSE: Ideomotor apraxia is a gestural deficit which is not due to primary sensory or motor deficit, poor auditory comprehension or incooperation. Previous studies on apraxia in AD patients include advanced AD patients who exhibited marked impairment in auditory comprehension, This might have confounded the results of the studies. The purpose of this study is to observe the frequencies and patterns of gestural errors in the early stage of AD. METHOD: Eighteen patients with AD (M : F = 4 : 14, age 62.6 + 7.2) and eighteen age- and sex- matched controls participated in this research. Patients who scored below 80 % of Western Aphasia Battery comprehension subtest and showed marked cognitive impairments were excluded (MMSE; 19.9 + 4.4, CDR 1.1+/- 0.5). Gestures. In response to commands were videotaped and analyzed by 2 neurologists and 1 speech-language pathologist. Test items included 3 types of movements ; 10 limb intrasitive, 15 transitive, and 10 buccofacial. RESULTS: Limb transitive movements were the most affected while buccofacial was the least. The error patterns most frequently observed were body-part-as-objects (BPO, 20%), external configuration orientation (ECO, 16%), and movement error(M, 9%). In comparision, BPO, ECO, M errors in normal control were 2%, 3%, and 4% respectively. In addition, apraxia item, which are to detecting AD were identified. CONCLUSION: It is suggested that the apraxia is commonly associated with AD even in the early stage of the disease and an accurate anaIysis of errors may contribute to establishing an early diagnosis of AD.
Alzheimer Disease* ; Aphasia ; Apraxia, Ideomotor* ; Apraxias ; Comprehension ; Early Diagnosis ; Extremities ; Gestures ; Humans

Cutaneous neuromas are uncommon, and three true neuromas exist in the skin: palisaded encapsulated neuroma, multiple mucosal neuroma, and traumatic neuroma. Traumatic neuroma is usually a solitary, skin-colored or pink, firm papule or nodule at the site a of scar following local trauma. The patient was a 51-year-old female and presented with a solitary 1X2X1.5cm sized erythematous to brownish tender polypoid firm mass on the left shoulder for 24 years. Although she could not remember any history of trauma or surgery on the lesional area, this case could be considered as traumatic neuroma on the basis of both the clinical and characteristic histological features and by ruling out other types of neuroma.
Cicatrix ; Female ; Humans ; Middle Aged ; Neuroma* ; Shoulder ; Skin

Anhidrotic ectodermal dysplasia(AED) is a rare hereditary disorder characterized by hypohidrosis or anhidrosis, hypotrichosis, dental hypoplasia and characteristic facies. Additional less consistent symptoms include nail dystrophy, hyperkeratosis of the palms and soles, cleft palate, hyperplasia of facial sebaceous glands, susceptibility to atopic dermatitis, dryness of mouth and eyes, and hypoplasia of mucous and mammary glands. In general, the inheritance of this syndrome is determined by an X-linked recessive gene, and several hundred cases, of which over 90% are male, have been reported in many differnt races. We experienced a case of AED associated with atopic dermatis.
Cleft Palate ; Continental Population Groups ; Dermatitis, Atopic* ; Ectoderm ; Ectodermal Dysplasia* ; Facies ; Genes, Recessive ; Humans ; Hyperplasia ; Hypohidrosis ; Hypotrichosis ; Male ; Mammary Glands, Human ; Mouth ; Sebaceous Glands ; Wills

BACKGROUND: Dimethyl sulfoxide (DMSO) acts as an urticariogenic agent or a primary irritant, and a DMSO skin test which measures responses in skin after exposure for 5 minutes could be a simple and easy method in evaluating cutaneous irritation . Atopy is a hereditary allergy (such as atopic dermatitis, allergic rhinitis, asthma, or hay fever) characterized by symptoms produced upon exposure to the exciting antigen without inoculation . Some atopy such as atopic dermatitis are more likely to be susceptible to various irritants and have defects in cutaneous barrier function. OBJECTIVE: The purpose of this study was to compare the differences of cutaneous responses between atopy patients (atopic dermatitis and respiratory atopy) and normal persons after skin irritation with several concentrations of DMSO. METHODS: We used DMSO concentrations of 90%, 95% and 100%, and evaluated the skin responses such as visual scores by wheal, transepidermal water loss (TEWL) and erythema index (E-index) after DMSO testing on the forearm skin of atopic dermatitis patients, respiratory atopy patients and normal healthy persons. RESULTS: 1. The TEWL values were increased as DMSO concentrations increased, and both baseline and postirritation TEWL values of the lesional area in atopic dermatitis patients were higher than in normal areas of atopic dermatitis patients and in respiratory atopy patients and in normal persons. There were no maj or differences in baseline and postirritation TEWL values among the last three groups. 2. Both baseline and postirritation E-index of the lesional area in atopic dermatitis patients were higher than in normal areas of atopic dermatitis patients and in respiratory atopy patients and in normal persons . There were no significant increases in E-index after irritation with 90% and 95% DMSO of normal areas of atopic dermatitis patients and 95%, 100% DMSO of normal persons. Also, there were no differences in baseline and postirritation E-index among normal areas of atopic dermatitis patients and respiratory atopy patients and normal persons . 3.The visual scores were increased as DMSO concentrations increased. The visual scores of the lesional area in atopic dermatitis patients were likely to increase as DMSO concentrations increased than in normal areas of atopic dermatitis patients and in respiratory atopy patients and in normal persons. There were no differences in visual scores among normal areas of atopic dermatitis patients and respiratory atopy patients and normal persons. CONCLUSION: The lesional skin of atopic dermatitis is more susceptible to DMSO irritation. However, there were no significant differences in susceptibility to DMSO irritation between the normal skin of atopic dermatitis, the skin of respiratory atopy and the control group.
Asthma ; Dermatitis ; Dermatitis, Atopic ; Dimethyl Sulfoxide* ; Erythema ; Forearm ; Humans ; Hypersensitivity ; Irritants ; Rhinitis ; Skin Tests ; Skin*

No abstract available.
Lung*

BACKGROUND: Eczematous dermatitis is associated with severe pruritus, but there are only a few effective treatment modalities. Preliminary studies suggest that topical application of doxepin cream is effective in the treatment of eczematous dermatitis. OBJECTIVE: This study was undertaken to evaluate the efficacy and safety of topical 5% doxepin cream in reducing ruritus associated with eczematous dermatitis in Korea. METHODS: A total of 62 patients with eczematous dermatitis, who daily experienced severe pruritus for at least 1 week, were enrolled in the study. Five percent doxepin cream was applied twice a day on the baseline visit, and four times daily for up to 7 days. We evaluated pruritus scores using visual analog scales, which consisted of a 100-mm horizontal line labeled "no itch" and "worst itch imaginable" at opposite ends. RESULTS: Pruritus scores evaluated by patients revealed significantly-better improvement on each visit day. Furthermore, there was a significant decrease in the pruritus scores and erythema evaluated by physicians on each visit day. Furthermore, the most common adverse effects were a stinging sensation and aggravation of erythema at the site of application. CONCLUSION: Five percent doxepin cream is safe and effective in reducing pruritus in patients with eczematous dermatitis.
Bites and Stings ; Doxepin* ; Eczema* ; Erythema ; Humans ; Korea ; Pruritus ; Sensation ; Visual Analog Scale