No abstract available.
Aeromonas*

It has been well known that liver cirrhosis, regardless of its etiology, is an important predisposing factor in hepatocarcinogenesis. However, the type of cirrhosis in hepatocellular carcinoma(HCC)-bearing liver varies not only by geographic areas but also with the cirteria applied for morphological classification of cirrhosis. To elucidate the relationship between the nodule size of HCC-bearing cirrhotic liver and clinicopathologic features, we measured cirrhotic nodule areas of 49 surgically resected HCC cases using image analyzer. The morphological type of cirrhosis was predominantly macronodular(49%), and followed by mixed(37%) and micronodular(14%). Seventy percent of the cases showed seropositivity for HBsAg. The average area of cirrhotic nodules was significantly larger in HBsAg-positive cases(mean: 6.14 mm2) than that of HBsAg-negative cases(mean: 2.5 mm2)(p<0.05), and their size was bigger in cases with grossly expansile pattern of HCC than those cases with infiltrative ones(p<0.05). Based on the above findings, we assume that seropositivity of HBsAg may influence on the regenerative activity of cirrhotic nodules and also subsequent increase of risk for further development of HCC. The presence of cirrhohsis and nodule size seem to be the important contributing factors to determine the growing patterns of HCC.
Carcinoma, Hepatocellular

Hepatoid adenocarcinoma of the stomach has been designated to a primary gastric adenocarcinoma with minimum criteria of elevated serum alpha-fetoprotein and its histological resemblance to neoplastic liver cells. Of the 1,500 consecutive cases of surgically resected gastric carcinomas during a period of 4 years, we retrieved 14 cases of adenocarcinoma which met the histologic features of hepatoid growth and compared them histologically with 400 consecutive cases of non-hepatoid gastric adenocarcinomas. The patient's age ragned from 32 to 80 years(non-hepatoid group: 25 to 81 years) and their male to female ratio was 3.7 : 1(non-hepatoid group: 1.8 : 1). Grossly, five case were Borrmann type II and another five cases type III. All three cases of early gastric carcinomas were the submucosal type IIc. The remaining one was an advanced gastric carcinoma mimicking early gastric carcinoma. Microscopically, the hepatoid portions varied in growing patterns and arranged in either compact, trabecular or pseudoglandular pattern and gave an immunoreactivity to alpha-fetoprotein and alpha-1-antichymotrypsin. Regardless of the tumor stage, the hepatoid areas were located in the deeper portion of the tumor mass and grew in an expanding/nodular pattern. The associated adenocarcinomatous areas were mostly papillotubular, moderately to well differentiated, and frequently revealed clear PAS-negative cytoplasm reminiscent of the differentiated embryonal carcinoma. Tumor emboli and nodal metastasis were the frequent associations. We assume that the hepatoid adenocarcinoma may develop from gastric'adenocarcinoma through embryonal carcinomatous growth.
Female ; Male ; Humans ; Adenocarcinoma ; Neoplasm Metastasis

A 56-year-old man received subtotal gastrectomy for an early gastric carcinoma type IIa+IIc with submucosal invasion. The tumor was made up of mixed papillo-tubular adenocarcinoma and solid carcinomatous portion, the latter comprising approximately four-fifths of the total tumor mass. The solid portion was confined within the submucosa and revealed a mixture of trabecular, compact and pelioid patterns of large polyhedra cells, resembling hepatocellular carcinoma of the liver(Edmondson-Steiner grade 2). Sinusoid-like vascular stroma of classical trabecular hepatocellular carcinoma intervened the tumor cell nests but was not associated with endothelial-cell lining. Immunohistochemical stainings with alpha-fetoprotein and alpha1-antitrypsin gave a strong reactivity in those areas of hepatoid differentiation and in the adjacent minute portion of adenocarcinoma. The findings suggest that a portion of gastric carcinoma may transdifferentiate into cells with hepatoid features along the line of endodermal lineage.
Male ; Humans ; Adenocarcinoma ; Carcinoma, Hepatocellular

Although causes of restriction of knee extension in osteoarthritis are thought to be contractures involving the posterior capsule and the hamstring muscles, intercondylar notch stenosis, osteophyte, loose body, and displacement of ruptured meniscus, few studies have investigated incidence and treatment. The purpose of this study is to consider intercondylar notch stenosis and anterior impingement as major causes of flexion contracture in osteoarthritic knee and to assess their relationship through arthroscopic notchplasty. We performed arthroscopic notchplasty and debridement in sixty patients (sixty-eight cases) with more than Sflexion contracture for early osteoarthritic knee and compared flexion contracture before and after operation. The average flexion contracture was 13degrees (5degrees-35degrees) before operation and 4degrees (0degrees- 25degrees) immediately after. An average of 9degrees improvement was shown, with 29 cases ( 48% ) showing improvement of over 5degrees. Our study indicates that flexion contracture in the 29 cases (48%) improved by arthroscopic notchplasty was caused by intercondylar notch stenosis and anterior impingement. Arthroscopic notchplasty may beneficially affect those with flexion contracture in early osteoarthritic knee when conservative management of this disease has failed. This is a preliminary study on the immediate postoperative outcome, therefore, long-term follow-up and recurrence rate should be investigated in future studies.
Constriction, Pathologic ; Contracture ; Debridement ; Follow-Up Studies ; Humans ; Incidence ; Knee* ; Muscles ; Osteoarthritis ; Osteophyte ; Recurrence

Purpose: This study is a qualitative study that investigated the nature of Koreans’ spiritual health using a hybrid model, clarifying the definition and attributes of the concept. Methods: The nature and definition of Koreans’ spiritual health were identified through a review of the extensive literature at the theoretical stage and then compared with an analysis of the in-depth interview data conducted by the researcher in the fieldwork stage. Results: Koreans’ spiritual health comprised nine attributes: awareness of the meaning and purpose of life, self-awareness, self-acceptance and recognition, self-transcendence, self-integration, harmony of relationships, self-actualization and development, the inner affective attributes of hope, happiness, fulfillment and thankful mind, and the interpersonal affective attributes of one connected mind, compassion, generosity and humility. The scope of the Absolute is expanded to ‘heaven’ and ‘ancestors’, and harmony with the community is emphasized. Conclusion We have found that Koreans’ spiritual health is important for total nursing care and that mental, social and physical health can be improved if spiritual health is promoted. Considering this point, personal and organizational efforts are needed to ensure that spiritual nursing is positively applied in community and clinical settings.

Purpose: The purpose of this study was to investigate drinking as a health behavior during pregnancy. Methods: Secondary data obtained from the 2018 Korean Community Health Survey were analyzed using descriptive statistics, t-tests, Pearson correlation coefficients, and multiple regression analysis via the software IBM SPSS Statistics ver. 21.0. Results: The multiple regression analysis revealed that age, monthly income, job, depression, lifetime smoking habit, breakfast frequency, and experiences of unmet medical needs were significant drinkingrelated factors connected with health behaviors during pregnancy. Conclusion Several factors are associated with drinking during pregnancy. To improve health promotion during pregnancy, alcohol prevention programs should be developed that consider one’s socioeconomic status and health behaviors.

Purpose: This study is a qualitative study that investigated the nature of Koreans’ spiritual health using a hybrid model, clarifying the definition and attributes of the concept. Methods: The nature and definition of Koreans’ spiritual health were identified through a review of the extensive literature at the theoretical stage and then compared with an analysis of the in-depth interview data conducted by the researcher in the fieldwork stage. Results: Koreans’ spiritual health comprised nine attributes: awareness of the meaning and purpose of life, self-awareness, self-acceptance and recognition, self-transcendence, self-integration, harmony of relationships, self-actualization and development, the inner affective attributes of hope, happiness, fulfillment and thankful mind, and the interpersonal affective attributes of one connected mind, compassion, generosity and humility. The scope of the Absolute is expanded to ‘heaven’ and ‘ancestors’, and harmony with the community is emphasized. Conclusion We have found that Koreans’ spiritual health is important for total nursing care and that mental, social and physical health can be improved if spiritual health is promoted. Considering this point, personal and organizational efforts are needed to ensure that spiritual nursing is positively applied in community and clinical settings.

From March in 1991, central photorefractive keratectomy(CPRK) have performed to correct the 700 myopic eyes. With the example of 310 eyes posibly observed over 6 months after CPRK, studed whether it was corrected by retrospective examining. Especilly in the study of 150 patients collected by answering sheet then studied how discomfort they took through complication, and analyzed the cause of change and Indivisual degree of sansfaction with their myopic degree and postoperative permd. This study led to a conclusion that the milder myopia and the longer postoperative period, the more patients sansfaction increased. This is because the change of refractive power become stable and corneal haze decresase with time, Futhermore we dunk that corneal haze and regression occur more frequently in higher myopla, The CPRK is promising surgical treatment for patients with higher myopia but considerable further investigation and longer-term studies are needed to increase satisfaction.
Glare ; Humans ; Lasers, Excimer* ; Myopia ; Postoperative Period ; Retrospective Studies

No abstract available.
Escherichia coli* ; Escherichia*