To evaluate the character, management and clinical results of the posterior capsular rupture during cataract surgery, we retrospectively studied the cataract surgeries that were performed between May 1989 and Decemeber 1991. We discovered 64 eyes in which the posterior capsule was torn. The overall incidence of this complication was 4.4%. Our chart review of these surgical procedure revealed that the tear occurred most frequently during the nucleus removal(44%), occured more frequently at the periphery than the center and the extent was mostly below one-third of the whole posterior capsular surface(75%). We performed vitrectomy(58%) and peripheral iridectomy(14%). Posterior capsular lenses were implallted in 56 cases. The predicted power of lens calculated with SRK-II fomula and manufacturer's A-constant was approximately 0.46 diopter less than actual postoperative refraction. Final visual acuity of 20/40 or better was achieved in 73% of the 64 cases. Our results revealed that when properly managed, a torn posterior capsule is compatible with an excellent visual outcome.
Cataract* ; Incidence ; Retrospective Studies ; Rupture* ; Visual Acuity

The clinical and statistical evaluations of 25 patients(29 eyes) with subluxated lenses which were extracted at St. Mary's hospital from October 1984 to June 1990. The results were as follows: 1. The average age was 41.3 years and the sex distribution was 23 males and 2 females. 2. The causes were divided by 17 eyes(58.6%) with trauma and 12 eyes(41.4%) without trauma. 3. The associated diseases were cataract(9 eyes; 31.0%), glaucoma(6 eyes; 20.7%), retinal detachment(4 eyes; 13.8%) and uveitis(2 eyes; 6.9%). 4. There were 9 eyes(31.0%) in superonasal, 4 eyes(13.8%) in inferotemporal direction of lens displacement. 5. The surgical procedures were intracapsular cataract extraction(22 eyes; 75.9% ), lens aspiration(3 eyes; 10.3% ), extracapsular cataract extraction(1 eye 3.5% ) and pars plana lensectomy with vitrectomy(3 eyes; 10.3%). 6. There were 9 eyes(28.0%) associated with vitreous protrusion and the vitrectomy were done in 20 eyes(62.5% ). 7. Postoperative corrected visual acuity improved fairly. It was the same as preoperative corrected visual acuity in 7 eyes(24.1%), improved in 21 eyes(72.4%) and worse in 1 eye(3.4%).
Cataract ; Female ; Humans ; Male ; Retinaldehyde ; Sex Distribution ; Visual Acuity ; Vitrectomy

Several kinds of non-contact tonometers have been used since the first non-contact tonometer was introduced in the 1970's in order to measure intraocular pressure with easiness and accuracy. However several problems were still remained because of:he inaccuracy of the non-contact tonometer in high and low range of intraocular pressure. A new non-contact tonometer (Model CT-20, Japan) was recently introduced by Topcon Company to evaluate the clinical efficacy of the non-ccntact tonometers. The authors measured the intraocular pressure with Topcon tonometer, AO tonometer and Pulsair non-contat tonometer and compared the results with those measured with Goldmann tonometer. The results were as follows: 1) The correlation coefficient between Goldmann and Topcon tonometer was 0.8452 (p=0.001), Goldmann and Pulsair tonometer was 0.7084 (p=O.OOl) and Goldmann and AO tonometer was 0.6048 (p=O.OOl) in the normal eyes. 2) The correlation coefficient between Goldmann and Topcon tonometer was 0.8651 (p=0.0001) in the ocular hypertensive or open angle glaucoma eyes. 3) The correlation coefficient between Goldmann and Topcon tonometer was 0.6987 (p=0.000l) in the low lOP eyes. 4) The correlation coefficient between Goldmann and Topcon tonometer was 0.6829 (p=0.0001) in the high myopic eyes. As above, a new-contact tonometer (Model CT-20, Japan) made by Topcon Company was relatively accurate in measuring not only the intraocular pressure of normal eyes but that of ocular hypertensive, low IOP and high myopic eyes.
Glaucoma, Open-Angle ; Intraocular Pressure

Malignant lymphoma is neoplastic transformation of cells that reside predominantly in lymphoid tissues. Malignant lymphoma involving the eye is a rare disease. Malignant lymphoma of the lid is extremely rare. The authors experienced a case of malignant lymphoma involving the lid in a 62 year-old male patient. At first visit, the patient complained of a palpable painless mass on the left upper eye lid. Later, the malignant lymphoma was confirmed by histopathologic examination. As for treatment, the lid mass excision was performed and 10 MeV electron beam 4000 rad radiotherapy was followed.
Eyelids* ; Humans ; Lymphoid Tissue ; Lymphoma* ; Male ; Middle Aged ; Radiotherapy ; Rare Diseases

The majority of cardiac myxoma occur sporadically as isolated lesions in the left atrium of middle-aged women. However, a familial form and a syndrome form of this lesion have also been identified. The syndrome myxoma can present itself with pigmented skin lesions and peripheral or endocrine neoplasms. The familial and syndrome forms of cardiac myxomas can usually be distinguished from the sporadic form by their occurrences at younger ages, their unusual locations, the multicentricity of the lesions, and the presence of rare pathological conditions. In addition, a higher rate of recurrent lesions is usually associated with the familial and syndrome forms of this disease. We present a case of complex cardiac myxoma with pigmented skin lesions and breast myxoma and report it with a review of literature.
Breast ; Female ; Heart Atria ; Humans ; Myxoma* ; Nipples* ; Skin

PURPOSE: To evaluate segmentation reliability in diabetic macular edema (DME) estimates between a Cirrus™ HD-OCT image analysis algorithm and an Iowa reference algorithm, which are an automatic segmentation software. METHODS: Thirty eyes from 23 patients diagnosed with DME were included and underwent spectral-domain optical coherence scans (Cirrus™ HD-OCT). Central foveal thickness (CFT) and ganglion cell layer-inner plexiform layer segmentation data were compared with those produced by the Cirrus™ HD-OCT segmentation algorithm and Iowa reference algorithm. Measurement agreement was assessed using intraclass correlation (ICC) and segmentation errors were confirmed by 2 ophthalmologists. RESULTS: The mean CFT in the 1-mm central area determined by the manufacturer-supplied Cirrus software and Iowa reference algorithm was 512.07 ± 182.35 µm and 476.53 ± 32.36 µm, respectively (p < 0.05). The mean paired difference was 35.53 ± 92.46 µm (ICC, 0.929). Segmentation errors were demonstrated in eyes with a CFT less than 400 µm, specifically for 45% of scans obtained by the Cirrus algorithm and 9% from the Iowa algorithm; in eyes with a CFT equal to or higher than 400 µm, the error rates were 95% and 42%, respectively. CONCLUSIONS: CFT measurement in eyes with diabetic macular edema using the Cirrus algorithm and Iowa algorithm showed relatively high degrees of agreement and significant correlation. In eyes with a CFT equal to or higher than 400 µm, the Iowa algorithm showed higher reliability in retinal segmentation than the Cirrus algorithm.
Ganglion Cysts ; Humans ; Iowa ; Macular Edema* ; Retinaldehyde ; Tomography, Optical Coherence

Choledochal cysts in neonates and young infants take two forms: the choledochal cyst associated with biliary atresia (CCBA) and the choledochal cyst in the absence of biliary atresia (CC). Infants in both groups usually have similar clinical symptoms at presentation, but management and prognosis are different. While early portoenterostomy is required for CCBA, cyst excision with hepaticojejunostomy or choledochojejunostomy is usually performed for CC. The former shows a relatively poor prognosis, and the latter shows a better prognosis. Two infants who presented with clinical features of neonatal cholestasis, and clinically suspected to have choledochal cysts, were found on imaging studies and surgery to have extrahepatic bile duct atresia in association with choledochal cysts.
Bile Ducts, Extrahepatic ; Biliary Atresia* ; Choledochal Cyst* ; Choledochostomy ; Cholestasis ; Humans ; Infant ; Infant, Newborn ; Prognosis

OBJECTIVE: Comparison of protein expressions by two-dimensional gel electrophoresis (2-DE) in normal cervix and squamous cell carcinoma tissues in Korean women. METHODS: Normal cervix and squamous cell carcinoma tissues were solubilized with 2-DE buffer and the first dimension of PROTEAN IEF CELL, isoelectric focusing (IEF), was performed using pH3-10 linear IPG strips of 17 cm. And then running 12% sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) and sliver stain. Scanned image was analyzed using PDQuest 2-D softwareTM. Protein spot spectrum was identified by assisted laser desorption/ionization-time of fighting (MALDI-TOF) and the protein mass spectrum identifications were performed by searching protein databases of Swiss-prot/TrEMBL, Mascot and MS-FIT. RESULTS: We found 9 up-regulation proteins (Alpha enolase, Keratin 19 type I, Keratin 20 type I, Keratin 13 type I, beta-actin, Aflatoxin B1 aldehyde reductase 1, Annexin A2, Squamous cell carcinoma antigen 2, unknown), 7 down-reguation proteins (Annexin 1, Myosin regulatory light chain 2, 14-3-3 protein epsilon, Heat shock 27 kDa protein, Hypothetical protein (DKFZP434C1715), Tumor necrosis factor receptor superfamily member 13B, Smoth muscle protein 22-alpha) and 6 up and down-regulation proteins (Tropomyosin 1, Tropomyosin 2, Tropomyosin 3, Serine (or cysteine) proteinase inhibitor, Phosphatidylinositol transfer protein alpha isoform, Src homology 3 domain-containing protein HIP-55) between normal cervix and squamous cell carcinoma cell tissues. CONCLUSION: 2-DE offers total protein expressions between normal cervix and squamous cell carcinoma cell tissues, and searching of differently expressed protein for the diagnostic markers of squamous cell carcinoma tissue.
14-3-3 Proteins ; Actins ; Aflatoxin B1 ; Aldehyde Reductase ; Annexin A2 ; Carcinoma, Squamous Cell ; Cervix Uteri ; Databases, Protein ; Down-Regulation ; Electrophoresis, Gel, Two-Dimensional* ; Electrophoresis, Polyacrylamide Gel ; Female ; Hot Temperature ; Humans ; Isoelectric Focusing ; Keratin-13 ; Keratin-19 ; Keratin-20 ; Mass Spectrometry* ; Muscle Proteins ; Myosin Light Chains ; Phospholipid Transfer Proteins ; Phosphopyruvate Hydratase ; Receptors, Tumor Necrosis Factor ; Running ; Serine ; Shock ; Sodium Dodecyl Sulfate ; Tropomyosin ; Up-Regulation ; Uterine Cervical Neoplasms*