1.Nerepinephrine Secreting Pheochromocytoma in the Organ of Zuckerkandl With Epinephrine Granules in Cytoplasm
Eui Suk KIM ; Gang Ryong LEE ; Won Seok LEE ; Jeong Aa LEE ; Jie Jeong JANG ; In Cheol SUNWOO ; Dae Ha KIM ; Gwang Seob LEE
Journal of Korean Society of Endocrinology 1996;11(2):233-239
Extraadrenal pheochromocytomas developed from the paraganglia other than adrenal medulla are uncommon tumors. Such lesions have been reported that as much as 10% of retroperitoneal paragliomas arise outside the adrenal gland. But their incidence and prognosis are changing partly as a result of progression in developmental mechanism, diagnostic tools and concepts including ultrastructure, immunohistochemistry. The ultrastructure of chromaffine neoplasm from adrenal and extraadrenal tissues has been studied with chrarnaffine granule specificity and type of catecholamine content. With rare exceptions, extraadrenal chrornaffine tumor mainly has high concentration of norepinephrine which is suggested as dict relationship to numoruos electrone dense granular bodies in the cell cytoplasrn. High or intermediate level of epinephrine in tissue is associated with cytoplasmic granular bodies of much less density, Recently we experienced the exception, a case of norepinephrine secreting pheochrom-ocytoma in the organ of Zuckerkandl with epinephrine granules in cytoplasm and this discrepancy probably due to the plasticity
Adrenal Glands
;
Adrenal Medulla
;
Cytoplasm
;
Epinephrine
;
Immunohistochemistry
;
Incidence
;
Norepinephrine
;
Para-Aortic Bodies
;
Pheochromocytoma
;
Plastics
;
Prognosis
;
Sensitivity and Specificity
2.A Case of Total Anomalous Pulmonary Venous Confluence in Adult Diagnosed by Echocardiography.
Gwang Seob LEE ; Kwang Sub CHOI ; Sin Eung KIM ; In Chul SUN WOO ; Jong Mann KIM ; Mi Young JANG ; Chul Bum LEE
Korean Circulation Journal 1992;22(5):874-881
Total anomalous pulmonary venous confluence(TAPC), a rare cyanotic congenital anomaly of the heart especially in adult, is now diagnosed by echocardiography instead of cardiac catheterization with high sensitivity and specificity. The key points are identification of pulmonary veins, pulmonary venous confluence draining anomalously to the heart. RVDVO on M-mode, abnormal echo free space posterior to left atrium on 2D-echo are basic characteristics of TAPVC. Peak velocity and flow profile measurement on the doppler provide additional informations : obstruction and anomalous vessels. A case of 23 year old male with supracardiac type TAPVC diagnosed by echocardiography was corrected successfully by surgery.
Adult*
;
Cardiac Catheterization
;
Cardiac Catheters
;
Echocardiography*
;
Heart
;
Heart Atria
;
Humans
;
Male
;
Pulmonary Veins
;
Sensitivity and Specificity
;
Young Adult
3.A case of mycoplasma pneumonia which progressed to ARDS.
Eui Sook KIM ; Won Seok LEE ; Kang Ryung LEE ; Jeong Aa LEE ; Young Joo BAEK ; Gwang Seob LEE ; Incheol SUNWOO ; Dae Ha KIM ; Jie Jeong JANG
Tuberculosis and Respiratory Diseases 1996;43(4):645-650
Mycoplasma Pneumonia is a main cause of primary atypical pneumonia and may present in a variety of ways. One auther has stated that the infiltrate is of a lobar segmental type, while others have found the infiltrates to be mainly reticular or interstitial. We experienced a case of mycoplasama pneumonia, whic h progressed to ARDS pattern rapidly and recovered completely after ventilator care.
Mycoplasma*
;
Pneumonia
;
Pneumonia, Mycoplasma*
;
Ventilators, Mechanical
4.The Relationship between Stud Morphology and 5th Metatarsal Proximal Stress Fractures on Soccer Players.
Jun Young LEE ; Gwang Chul LEE ; Young Kwan LEE ; Yi Kyu PARK ; Sang Soo PARK ; Jun Seob SONG
The Korean Journal of Sports Medicine 2012;30(1):41-46
This research sets out to define the relationship between stud morphology of soccer shoes and 5th metatarsal proximal stress fractures on soccer players by comparison and analysis. After the pre-survey of 132 soccer players in Gwangju, 107 players who seem to have a 5th metatarsal fracture were selected. We investigated the shape of the studs and asked whether they had ever had a 5th metatarsal proximal stress fracture. We also asked them some questions on factors, which cause stress fracture, such as what position they play, how long they have been playing soccer as athletes and average playing time. And we analyzed correlation between these several factors and whether they had ever had stress fracture using chi-square (x2) test and Logistic regression analysis. We concluded that soccer players who wore bar type studs shoes had a much greater possibility of stress fracture than soccer players who wore the round type. Also we learned that soccer players who play mid-fielder have a much greater possibility of stress fracture than soccer players who play other positions. And the result of logistic regression analysis of relevance between soccer shoes stud morphology and stress fracture shows a statistically significant odd ratio, 6.840. It has been suggested that the morphology of the soccer shoes stud has relevance to the occurrence of stress fracture. Therefore, according to the result of this study, soccer shoes with the round shape are more helpful in preventing 5th metatarsal proximal stress fracture than soccer shoes with the bar shape.
Athletes
;
Fractures, Stress
;
Humans
;
Logistic Models
;
Metatarsal Bones
;
Shoes
;
Soccer
5.A Case of Giant Lipoma Causing Chronic Recurrent Intussusception of the Colon.
Chang Seob LEE ; Mi Jin LEE ; Kyoung Lee KIM ; Yeon Soo KIM ; Gwang Ho BAIK ; Jin Bong KIM ; Dong Joon KIM ; Sang Hak HAN
Clinical Endoscopy 2012;45(2):165-168
Colonic lipomas, which often occur in elderly women, usually have small size and occur mainly in the cecum and ascending colon. Most colonic lipomas are asymptomatic and identified incidentally at the time of endoscopy or surgery. However, they may cause symptoms such as bleeding, obstruction or intussusception as their size increases. Intermittent episodes of intussusception are uncommon but may be caused by large pedunculated lipoma. In a 68-year-old woman suffering intermittent abdominal pain, 5.5x4.5x3.8-cm huge mass was found by colonoscopy at proximal ascending colon, which was intussuscepted to proximal transverse colon on abdominal computed tomography. Segmental right colonic resection was conducted. We report a case of symptomatic giant pedunculated colonic lipoma causing intussusception requiring surgical intervention, with a successful recovery after surgery.
Abdominal Pain
;
Aged
;
Cecum
;
Colon
;
Colon, Ascending
;
Colon, Transverse
;
Colonoscopy
;
Endoscopy
;
Female
;
Hemorrhage
;
Humans
;
Intussusception
;
Lipoma
;
Stress, Psychological
6.A case of single cervical tuberculous cold abscess associated with multi-loculated tuberculous pleurisy.
Jeong Aa LEE ; Eui Sook KIM ; Young Joo BAEK ; Gwang Seob LEE ; Incheol SUNWOO ; Dae Ha KIM ; Jie Jeong JANG ; Suck Min PARK ; Mi Kyung JI
Tuberculosis and Respiratory Diseases 1996;43(3):434-439
St. Francisco General Hospital, Seoul, Korea. Although the incidence of pulmonary tuberculosis is declining, the number of extrapulmonary tuberculosis has remained constant. Tuberculous Lymphadenitis accounts for over 50% of total inflammatory lymphadenitis and the most common site is cervical lymph node. We report a case of single cervical tuberculous cold abscess associated with multiloculated and septated tuberculous pleurisy. Intracavitary urokinase instillation via percutaneous catheter is indicated in loculated and septated pleural effusion. And our result was satisfactory without complication.
Abscess*
;
Catheters
;
Hospitals, General
;
Incidence
;
Korea
;
Lymph Nodes
;
Lymphadenitis
;
Pleural Effusion
;
Seoul
;
Tuberculosis
;
Tuberculosis, Lymph Node
;
Tuberculosis, Pleural*
;
Tuberculosis, Pulmonary
;
Urokinase-Type Plasminogen Activator
7.Safety and Tolerability of the Dual 5-Alpha Reductase Inhibitor Dutasteride in the Treatment of Androgenetic Alopecia.
Gwang Seong CHOI ; Joon Hyung KIM ; Shin Young OH ; Jung Min PARK ; Ji Soo HONG ; Yil Seob LEE ; Won Soo LEE
Annals of Dermatology 2016;28(4):444-450
BACKGROUND: After the approval of dutastride for androgenic alopecia (AGA) in 2009, Korean authority required a post-marketing surveillance to obtain further data on its safety profile. OBJECTIVE: The objective was to monitor adverse events (AEs) of dutasteride 0.5 mg in Korean AGA male patients in a clinical practice environment. METHODS: Open label, multi-center, non-interventional observational study was done from July 2009 to July 2013. AGA subjects (18~41 years of age) with no experience of dutasteride were enrolled. Dosage regimen was recommended according to the prescribing information. The incidences of any AEs, serious adverse events (SAEs), and adverse drug reactions (ADRs) were evaluated. Multiple logistic regression method was used to identify risk factors related to ADRs. Effectiveness was generally evaluated by physicians. RESULTS: During study period, 712 subjects were enrolled. The subjects of 29.3±6.0 years old exposed to dutasteride for 204.7±161.5 days. One hundred and ten (15.4%) of subjects reported 138 AEs. Four subjects (0.6%) reported 5 SAEs (right radius fracture, 2 events of chronic follicular tonsillitis, influenza infection, and acute appendicitis). Sixty-six subjects (9.3%) reported 80 ADRs. Most frequent ADRs were libido decreased (9 subjects, 1.3%), dyspepsia (8 subjects, 1.1%), impotence (7 subjects, 1.0%), and fatigue (5 subjects, 0.7%). Other interested ADRs were sexual function abnormality (4 subjects, 0.6%), gynecomastia (2 subjects, 0.3%), and ejaculation disorder (1 subject, 0.1%). Most subjects (78.6%) showed overall improvement after treatment of dutasteride in the effectiveness. CONCLUSION: Dutasteride 0.5 mg is to be well-tolerated in 18 to 41 years old AGA patients in a clinical practice environment.
Alopecia*
;
Drug-Related Side Effects and Adverse Reactions
;
Dutasteride*
;
Dyspepsia
;
Ejaculation
;
Erectile Dysfunction
;
Fatigue
;
Gynecomastia
;
Humans
;
Incidence
;
Influenza, Human
;
Libido
;
Logistic Models
;
Male
;
Methods
;
Observational Study
;
Oxidoreductases*
;
Palatine Tonsil
;
Radius Fractures
;
Risk Factors
;
Tonsillitis
;
Treatment Outcome
8.Acute Pancreatitis after Extracorporeal Shock Wave Lithotripsy for a Urolithiasis.
Jung Un HONG ; Byung Min JOHN ; Tae Seob JUNG ; In Young NOH ; Nam Kyu KANG ; In Sun MIN ; Ju Young LEE ; Hae Sung KIM
Korean Journal of Pancreas and Biliary Tract 2016;21(2):82-86
48-year-old woman was admitted to emergency room due to left flank pain. It was diagnosed with left ureteral stone and underwent extracorporeal shock wave lithotripsy (ESWL). However, 12 hours later, the patient complained acute upper abdominal pain with pulmonary edema and low blood pressure. A diagnosis of moderate acute pancreatitis with local complication was considered and we decided conservative therapy including fluid resuscitation, inotropics and antibiotics. It was suggested that ESWL was responsible for the acute pancreatitis. The patient gradually recovered and was discharged on 13th day of admission. ESWL is considered the standard treatment for urolithiasis. Although, it has proved to be safe and effective, serious complications have been reported in 1% of patients, including acute pancreatitis, perirenal hematoma, urosepsis, venous thrombosis, biliary obstruction, bowel perforation, lung injury, and cardiac arrhythmia. Although the possibility of post-ESWL acute pancreatitis is extremely low, physicians should take care of this complication.
Abdominal Pain
;
Anti-Bacterial Agents
;
Arrhythmias, Cardiac
;
Diagnosis
;
Emergency Service, Hospital
;
Female
;
Flank Pain
;
Hematoma
;
Humans
;
Hypotension
;
Lithotripsy*
;
Lung Injury
;
Middle Aged
;
Pancreatitis*
;
Pulmonary Edema
;
Resuscitation
;
Shock*
;
Ureter
;
Urolithiasis*
;
Venous Thrombosis
9.A Case of Congenital Cystic Adenomatoid Malformation of the Lung Containing Fungal ball-like movable Blood clots in Healthy Young Woman.
Gang Ryong LEE ; Kun Sun LEE ; In Kyu JOO ; Seung Jun CHOI ; June Ock PARK ; Won Seok LEE ; Eui Sook KIM ; Dae Ha KIM ; Gwang Seob LEE ; Young Sook HAN ; Mi Kyeng JEE ; Jung Woong PARK
Tuberculosis and Respiratory Diseases 1999;46(1):129-135
We describe unusual manifestations of congenital cystic adenomatoid malformation ( C.C.A.M.) of the lung, such as movable fungal ball-like intracystic blood clots and hemoptysis, which were detected in previously healthy 23 years-old woman. We identified blood clots only after left upper lobectomy and could not distinguish from fungal ball with radiographic methods. CCAM of the lung, rare and lethal form of congenital pulmonary cystic disease, was initially introduced by Ch'in and Tang in 1949. The histogenesis of this lesion is characterized by polypoid glandular tissue proliferation and overgrowth of mesenchymal elements due to cessation of bronchiolar maturation which occured in after 16weeks intrauterine period. In 80-95% of reported cases, the lesion was confined to a single lobe and there was no lobe and right and left lung predilection. The clinical presentation may be widely variable, ranging from intrauterine fetal death to late discovery in childhood with recurrent pulmonary infection. But there's no reports which were misdiagnosed with intracystic fungal ball. The treatment choice is lobectomy of affected lobe. There's a few case reports with rhabdomyosarcoma, bronchiolar cell carcinoma and myxosarcoma arising in CCAM patients. Therefore, early resection is recommended even if asymtomatic cases. We experienced a rare case of CCAM of the lung in 23 years old female, and there were intracystic fungal ball-like movable blood clots in lower portion of left lung. After left upper lobectomy was performed, now she is discharged and followed up without any complications.
Cystic Adenomatoid Malformation of Lung, Congenital*
;
Female
;
Fetal Death
;
Hemoptysis
;
Hemorrhage
;
Humans
;
Lung*
;
Myxosarcoma
;
Rhabdomyosarcoma
;
Young Adult
10.A Case of Congenital Cystic Adenomatoid Malformation of the Lung.
Young Joo BAEK ; Jeong Aa LEE ; Eui Sook KIM ; Won Seok LEE ; Kang Ryang LEE ; Gwang Seob LEE ; Synn Eung KIM ; In Cheol SUNWOO ; Dae Ha KIM ; Jie Jeong JANG ; Young Sook HAN ; Mi Kyeng JEE
Korean Journal of Medicine 1997;52(1):143-147
Congenital cystic adenomatoid malformation(C.C. A.M.) is a rare variant of congenital pulmonary cystic diseases. C.C.A.M. was first distinguished from other pulmonary cystic lesions by Ch`in and Tang in 1949. It is characterized by cessation of bronchiolar maturation with an overgrowth of mesenchymal elements and proliferation of polypoid glandular tissue in the absence of normal alveolar differentiation. In 80% to 95% of cases, C.C.A.M. of the lung is confinded to a single lobe and there is no lobe predilection and right and left predominance. The clinical presentation may be widely variable, ranging from intrauterine fetal death secondary to nonimmune hydrops fetalis to discovery in childhood after recurrent pulmonary infections. Definitive treatment is removal of affected lobe. In rare instances, there is cases of myxosarcoma, embryonal rhabdomyosarcoma. Bronchoalveolar carcinoma arising in C.C.A.M.. So, resection is recommended even if they are asymtomatic. We have experienced a case of congenital cystic adenomatoid malformation (type II) of the lung in 15 year old man with pneumonia. After the improvement of pneumonia, surgical operation was performed. A brief review of the related literature is presented.
Adolescent
;
Cystic Adenomatoid Malformation of Lung, Congenital*
;
Fetal Death
;
Humans
;
Hydrops Fetalis
;
Lung*
;
Myxosarcoma
;
Pneumonia
;
Rhabdomyosarcoma, Embryonal