1.The Relationship of Bone Mineral Densities and Period of Breast feeding in Premenopausal Women.
Eun Nam LEE ; Eun Ok LEE ; Gwang Hae LEE
Journal of Korean Academy of Nursing 2000;30(1):29-38
To determine whether personal history of lactation in premenopausal women influence bone mineral density, a cross-sectional study was conducted. One hundred eighty-four premenopausal women were selected from women who had been checked for bone mineral density by dual energy x-ray absortiometry in lumbar spine, femoral neck, Ward's triangle, and trochanteric site at general hospitals in Seoul and Pusan. They completed a questionnaire including life style factors and reproductive history. In the data analysis, Pearson correlation coefficients were used to test any association between individual variables and bone mineral density and a statistical comparisons between long term lactation(>24 months) and short term lactation(<24 months) were made by one way analysis of covariance. The results were summarized as follows: 1) There was no significant difference in the bone mineral density of the lumbar vertebrae in premenopausal women between the long term lactation group(>24months) and the short term lactation group(<24months). 2) There was no significant difference in the bone mineral density of the femur neck, Ward's triangle, and trochanteric site in premenopausal women between the long term lactation group (>24months) and the short term lactation group (<24months). Considering these results, we suggest prospective studies that measure bone mineral density before and after, in addition to those during lactation. We also suggest the further study with premenopausal women less than 35 who have achieved peak adult bone mass.
Adult
;
Bone Density*
;
Breast Feeding*
;
Breast*
;
Busan
;
Cross-Sectional Studies
;
Female
;
Femur
;
Femur Neck
;
Hospitals, General
;
Humans
;
Lactation
;
Life Style
;
Lumbar Vertebrae
;
Surveys and Questionnaires
;
Reproductive History
;
Seoul
;
Spine
;
Statistics as Topic
2.Clinical Study of Neonatal Adrenal Lemorrhage.
Gwang Hoon LEE ; Eell RYOO ; Kang Ho CHO ; Sang Hee KIM ; Kil Hyun KIM ; Hak Soo LEE ; Ji Hae KIM
Journal of the Korean Society of Neonatology 1997;4(2):246-252
PURPOSE: Neonatal adrenal hemorrhage is not rare disease which can be caused by such risk factors as sepsis, large baby, birth trauma and asphyxia. The clinical manifestations include jaundice, anemia, abdominal mass and differentiation from neuroblastoma, renal vein thrombosis and adrenal abscess is needed. Through the clinical assessment of presenting features, we hope that this study be of any help to early detection and proper management of neonatal adrenal hemorrhage. METHODS: The 16 subjects out of neonates admitted to our hospital from July 1991 to June 1997 were diagnosed as neonatal adrenal hemorrhage. The risk factors, clinical manifestations, diagnostic methods and prognosis of neonatal adrenal hemorrhage were evaluated in these 16 cases. RESULTS: 1) Among 16 cases, males were 10 (62.5%) and females were 6 (37.5%). Mean birth weight was 3.601.08kg and mean gestational age was 39.82+1.08 week, and all were fullterm babies. In modes of delivery, vaginal deliveries were 12 cases (75.0%) and cesarean sections were 4 cases (25.0%). 2) 13 cases (81.2%) were involved in right side, 2 cases (12.5%) in left side and 1 case (6.3%) bilaterally. 3) The risk factors include sepsis in 6 cases (37.5%), large baby in 5 cases (31.3%), birth trauma in 5 cases<31.3%) and asphyxia in 3 cases (18.8%). 4) The clinical manifestations include jaundice in 7 cases (43.8%), anemia in 7 cases (43.8%), fever in 6 cases (37.5%) and abdominal mass in 3 cases (18.8%). 5) In the time of diagnosis, until 7 days of birth were 9 cases (56.2%), 8-14 days were 3 cases (18.8%), 15-21 days were 2 cases (12.5%) and 22-28 days were 2 cases (12.5%). Follow-up studies were done in 13 cases (81.2%), and tha lesions all decreased without any specific complications or sequelae. CONCLUSION: Neonatal adrenal hemorrhage can be diagnosed by abdominal ultrasono- gram in the presence of suggestive manifestations of jaundice, anemia, fever and abdominal mass, with relatively good prognosis. Differentiation from other conditions as well as avoidance of unnecessary explorations can be achieved by serial follow-up examinations of abdominal ultrasonogram.
Abscess
;
Anemia
;
Asphyxia
;
Birth Weight
;
Cesarean Section
;
Diagnosis
;
Female
;
Fever
;
Follow-Up Studies
;
Gestational Age
;
Hemorrhage
;
Hope
;
Humans
;
Infant, Newborn
;
Jaundice
;
Male
;
Neuroblastoma
;
Parturition
;
Pregnancy
;
Prognosis
;
Rare Diseases
;
Renal Veins
;
Risk Factors
;
Sepsis
;
Thrombosis
;
Ultrasonography
3.Acute Simultaneous Ruptures of the Anterior Cruciate Ligament and Patellar Tendon
Dong Hwi KIM ; Gwang Chul LEE ; Sung Hae PARK
The Journal of Korean Knee Society 2014;26(1):56-60
Acute simultaneous rupture of the anterior cruciate ligament (ACL) and patellar tendon is a rare injury. We present a case report of a 32-year-old male patient with ruptured ACL and ipsilateral patellar tendon rupture sustained while playing baseball. Surgery was performed on the patellar tendon and the ACL simultaneously. The clinical and radiological outcomes of the treatment were successful. We present this case with a review of the literatures.
Adult
;
Anterior Cruciate Ligament
;
Baseball
;
Humans
;
Male
;
Patellar Ligament
;
Rupture
4.Popliteal Artery Pseudoaneurysm after Anterior Cruciate Ligament Re-Revision Using a Rigidfix Cross Pin
Gwang Chul LEE ; Dong Hwi KIM ; Sung Hae PARK
The Journal of Korean Knee Society 2014;26(2):121-124
Popliteal artery injury is a very rare complication of anterior cruciate ligament (ACL) reconstruction. The authors experienced a case of popliteal arterial pseudoaneurysm after re-revision of ACL reconstruction using Rigidfix for femoral tunnel fixation. Pseudoaneurysm was detected in knee magnetic resonance imaging, which caused pain, limit of motion, common peroneal nerve palsy, leg swelling and symptoms similar to compartment syndrome. After excision and re-anastomosis of the popliteal artery using a greater saphenous vein graft, all symptoms were resolved within 3 months except for common peroneal nerve palsy. So we report on this case with a review of the literature.
Aneurysm, False
;
Anterior Cruciate Ligament
;
Compartment Syndromes
;
Knee
;
Leg
;
Magnetic Resonance Imaging
;
Paralysis
;
Peroneal Nerve
;
Popliteal Artery
;
Saphenous Vein
;
Transplants
5.Gastric adenocarcinoma with enteroblastic differentiation in a 67-year-old man in Korea:a case report
Hae Rin LEE ; Gwang Ha KIM ; Dong Chan JOO ; Moon Won LEE ; Bong Eun LEE ; Kyung Bin KIM
The Ewha Medical Journal 2024;47(2):e28-
We report a rare case of gastric adenocarcinoma with enteroblastic differentiation (GAED) that was treated with endoscopic submucosal dissection followed by additional distal gastrectomy with lymph node dissection. A 67-year-old man underwent endoscopic submucosal dissection for a gastric lesion, which was diagnosed as GAED with submucosal and lymphatic invasion. Histologically, GAED is characterized by a tubulopapillary growth pattern and clear cells that resemble those of the primitive fetal gut. Immunohistochemically, GAED variably expresses oncofetal proteins such as glypican-3, alpha-fetoprotein, and spalt-like transcription factor 4. Despite negative margins, additional gastrectomy with lymph node dissection was performed due to submucosal and lymphatic invasion.No residual tumor or metastasis was detected, and the patient remained disease-free for 2 years before dying from causes unrelated to GAED. Given its aggressive nature, frequent lymphovascular invasion, and high metastatic potential, clinicians should recognize the histopathological diagnosis of this rare tumor and its propensity for aggressiveness.
6.The Effect of Congenital Gut Obstruction on Fetal Growth.
Hae Joong YOON ; Sang Hee KIM ; Gwang Hoon LEE ; Hyoung Won LEE ; Kye Hwan SEOL ; Kil Hyun KIM ; Seung Yeon CHO
Journal of the Korean Society of Neonatology 1997;4(2):233-237
PURPOSE: The human fetus is primarily dependent on the placenta for its nutrition. However, as the fetus matures, it swallows increasing amounts of amniotic fluid, which contributes to the growth of fetus. Accordingly fetuses with congenital obstruction of the gut at high level have a reduced capacity for intestinal absorption of amniotic fluid. We undertook a study to investigate the effect of congenital gut obstruction on fetal growth. METHOD: A retrospective review of the records of all patients presenting congenital gut obstruction over 6-year period (from 1992 to 1997) in Chung-ang Gil hospital was performed. Patients with a complete proximal obstruction were included in group A; patients with incomplete or lower obstruction were included in group B. RESULT: 1) The ratio of male to female was 1.5:1. The mean birth weight and gestational age were 2.89+/-0.60kg and 38.7+/-0.20weeks. The mean birth weight and gestational age in group A were 2.68+/-0.69kg and 37.8+/-0.25weeks. The mean birth weight and gesnal age in group B were 2.980.54kg and 39.1+0.17weeks. There was significant difference between group A and B (P<0.01). 2) Significant differences were found between group A and B in prematurity and growth retardation rate (P<0.01). No significant difference was found between group A and B in associated anomaly rate (P>0.05). 3) In group A, 3 (42.8%) of 7 patients with associated anomalies had IUGR, whereas 8 (40.0%) of 20 patients without associated anomalies had IUGR (P>0.05). The corresponding figures for group B were 23.0% and 14.8%, respectively (P>0.05). CONCLUSION: Congenital gut obstruction causes IUGR by reducing intestinal absorption of amniotic fluid and the effect of IUGR is more pronounced as the obstruction is proximal to jejunum rather than distal to it.
Amniotic Fluid
;
Birth Weight
;
Female
;
Fetal Development*
;
Fetal Growth Retardation
;
Fetus
;
Gestational Age
;
Humans
;
Intestinal Absorption
;
Jejunum
;
Male
;
Placenta
;
Retrospective Studies
;
Swallows
7.A case of abdominal actinomycosis that occured on psous muscle.
Gwang Hwy KIM ; Hong Soo LEE ; Kyung Hwan JIN ; Jun Sik KIM ; Bo Kyung JEONG ; Eun Hee LEE ; Hae Ran YANG ; Myung Hyun NAM
Korean Journal of Infectious Diseases 1992;24(3):221-225
No abstract available.
Actinomycosis*
8.Expression of Smad 2 and 3 on the Lesions of Leprosy.
Hyeon Sook LEE ; Jong Rok LEE ; Gwang Seong CHOI ; Jeong Hyun SHIN ; Hae Young CHOI
Korean Journal of Dermatology 2006;44(3):304-308
BACKGROUND: Leprosy is an infectious disease with two polar forms, tuberculoid leprosy (TT) and lepromatous leprosy (LL), that are characterized by strong cell-mediated immunity (CMI) and CMI anergy, respectively. Transforming growth factor-beta (TGF-beta) is a family of growth factors involved in essential physiological processes, including development, differentiation, tissue repair, cell growth control and inflammation. Cellular signaling by TGF-beta family members is initiated by the assembly of specific cell surface receptors that activate transcription factors of the Smad family. Deregulation of the TGF-beta-Smad signaling pathway has been implicated in developmental disorders and several human diseases. Recently, ELISA & immunohistochemistry revealed high expression of TGF-beta isoforms in LL. OBJECTIVE: The purpose of this study was to investigate TGF-beta-Smad signaling in various forms of leprosy. METHODS: We investigated the involvement of TGF-beta by immunohistochemical staining for Smad 2 and 3 in skin biopsies from six patients of BL and four patients of TT. RESULTS: The inflammatory cells, keratinocytes and fibroblasts in BL showed strong positivity for both Smad 2 and 3, whereas those in TT showed little positivity. CONCLUSION: The high expression of Smad 2/3 in BL could represent high expression of TGF-beta, which possibly contributes to local CMI anergy and other clinical characteristic features of leprosy.
Biopsy
;
Communicable Diseases
;
Enzyme-Linked Immunosorbent Assay
;
Fibroblasts
;
Humans
;
Immunity, Cellular
;
Immunohistochemistry
;
Inflammation
;
Intercellular Signaling Peptides and Proteins
;
Keratinocytes
;
Leprosy*
;
Leprosy, Lepromatous
;
Leprosy, Tuberculoid
;
Physiological Processes
;
Protein Isoforms
;
Receptors, Cell Surface
;
Skin
;
Transcription Factors
;
Transforming Growth Factor beta
9.A Case of Mastocytosis in Three-month-old Female Infant.
Gwang Cheon JANG ; Jong Won LEE ; Eun Kyoung YOU ; Hae Young YOUM ; Kyu Earn KIM ; Soo Chan KIM
Pediatric Allergy and Respiratory Disease 2001;11(1):67-71
Mastocytosis is rare disorder characterized by the overproliferation and accumulation of tissue mast cells and spontaneous regression before adolescence in childhood, almost. Clinical features are vary and depend on local accumulation of mast cells in different organs and the effects of their mediators. Mast cell disease is commonly involved in the skin, and occasionally gastrointestinal tract, bone marrow, liver, spleen and lymphoid organs as well. Mastocytosis occurs equally in persons of each gender and it affects all age groups. The incidence is unknown and familial tendency is unusual. We are reporting a case of mastocytosis confirmed by skin biopsy who was visited for skin lesions that skin rashes at 10 days after birth, change to bullar at 3 month later.
Adolescent
;
Biopsy
;
Bone Marrow
;
Exanthema
;
Female*
;
Gastrointestinal Tract
;
Humans
;
Incidence
;
Infant*
;
Liver
;
Mast Cells
;
Mastocytosis*
;
Parturition
;
Skin
;
Spleen
10.A Case of Pulmonary Inflammatory Pseudotumor.
Hong KOH ; Hyun Wook CHAE ; Su Jin LEE ; Bong Shik YOON ; Gwang Cheon JANG ; Kyung Hoon KANG ; Jeong Hae KIE
Pediatric Allergy and Respiratory Disease 2006;16(3):248-252
Inflammatory pseudotumor of the lung is considered to be a rare, benign, neoplastic lesion, consisting mainly of spindle mesenchymal cells, sometimes in such a way that its histological appearance mimics that of a spindle cell sarcoma, fibrous histiocytoma or fibrosarcoma. A case of inflammatory pseudotumor of the lung occurring in a 13-year-old boy is reported with pathologic findings, including its ultrastructure. The patient had had no symptoms and accidentally discovered his condition after a chest X-ray examination at a regular school physical check up. The mass was located in the suprahilar area of the left lung. Exploratory thoracotomy revealed a large mass that was removed, together with the left upper lobe of the lung. Microscopically, the mass was composed of numerous interstitial inflammatory cells, mainly lymphoplasma cells. Ultrastructurally, the spindle-shaped mesenchymal cells were arranged haphazadly and the normal pulmonary structure was nearly totally destroyed. Emphasis is given to complete resection of the tumor for both diagnostic and therapeutic purposes.
Adolescent
;
Child
;
Fibrosarcoma
;
Granuloma, Plasma Cell
;
Histiocytoma, Benign Fibrous
;
Humans
;
Lung
;
Male
;
Plasma Cell Granuloma, Pulmonary*
;
Sarcoma
;
Thoracotomy
;
Thorax