1.Reflection on enhancing medical humanitarian activities in clinical teaching
Changyan LU ; Guozhong JI ; Jinfan WANG
Chinese Journal of Medical Education Research 2013;(2):187-190
Enhancing medical humanitarian activities in clinical teaching is demanded by modern medicine and education.It contains the modern values of constructing a harmonious doctor-patientrelationship and adjusting to medical education and modern medical model development.We put forward several countermeasures such as establishing concept of respect for people,improving teachers'humanistic caring ability,strengthening management to enhance students' sense of responsibility,enhancing students' doctor-patient communication skills,and abiding by relevant laws and regulations in the current situation which lacks humanistic care,doctor-patient communication and legal concept.
2.Properties and biocompatibility of collagen scaffold modified by genipin cross-linked L-lysine.
Donglin JIANG ; Junyu YANG ; Shengyang JIANG ; Guozhong LU ; Peng ZHAO
Journal of Biomedical Engineering 2014;31(4):816-821
Collagen (Coll), as the basic material of matrix scaffolds for cell growth, has been widely used in the field of tissue engineering and regenerative medicine. In this study, collagen protein was modified by L-lysine (Lys), and cross-linked by genipin (GN) to prepare the L-lysine-modified collagen (Lys-Coll-GN) scaffolds. Microstructure, pore size, porosity, stability and biocompatibility of Lys-Coll-GN scaffolds were observed. The results showed that the bond between L-lysine and collagen protein molecule was formed by generating amide linkage, and mouse embryo fibroblasts proliferation was not inhibited in the Lys-Coll-GN scaffolds. In the multiple comparisons of Coll-scaf- folds, Coll-GN scaffolds and Lys-Coll-GN scaffolds, Coll-scaffolds was the worst in mechanical characteristics while the highest in biodegradation rate. Compared to Coll-GN scaffolds, Lys-Coll-GN scaffolds had more fiber structure, higher interval porosity (P<0. 01). Although the tensile stress of Lys-Coll-GN scaffolds reduced significantly, its e- longation length extended when the scaffolds was fractured (P<0. 01). The percentage of Lys-Coll-GN scaffolds residual weight was lower than that of Coll-GN scaffolds after all the scaffolds were treated by collagenase for 5 days (P<0. 01). This study suggested that Lys-Coll-GN scaffold had good biocompatibility, and it improved the mechanical property and degradation velocity for collagen-based scaffold. This study gave a new predominant type of tissue engineering scaffold for the regenerative medicine.
Animals
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Biocompatible Materials
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chemistry
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Cell Proliferation
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Collagen
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chemistry
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Cross-Linking Reagents
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Fibroblasts
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cytology
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Iridoids
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chemistry
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Lysine
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chemistry
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Mice
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Porosity
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Tissue Engineering
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Tissue Scaffolds
4.Multi-functional Portable Bento for Single Field Soldier
Guozhong LU ; Yin-Sheng LIU ; Xiao-Dong LIU ;
Chinese Medical Equipment Journal 1989;0(02):-
Objective To design a multi-functional portable bento for single field soldier by reducing the health load of the army and improving the fighting capacity.Methods It is designed by selecting the suitable material and integrating the minimal volume with function.Results The bento can be designed on light material,small in size and used in water or waterless condition.Conclusion The bento is fit for the field army request to carry picnic tool and can improve the combat effectiveness of the force.
5.Application of Kangxiuke apozem in the treatment of severe burn shock
Liangliang CAI ; Longwei XIE ; Junjie YU ; Guozhong Lü ; Jingen LU ; Lingtao DING
International Journal of Traditional Chinese Medicine 2012;34(9):794-796
ObjectiveTo observe the clinical effect of Kangxiuke apozem in the treatment of severe bum shock.Methods40 patients of severe burn shock were randomly divided into a treatment group and a control group,with 20 patients in each group.All the patients were treated by the same route of counter-shock therapy,and the treatment group was additionally given Kangxiuke apozem (nasal feeding,qd,150 ml/d).Level of blood lactic acid,heart rate and urinary volume were evaluated by time.Main shock symptoms,including restlessness,hydrodipsia,perspiration and coldness,were observed.ResultsThe treatment group was significantly superior to the control group in the amelioration of blood lactic acid,heart rate and urinary volume ( t =10.485、3.219、7.429,P< 0.01 ).The symptomatic extinction of restlessness,hydrodipsia,perspiration and coldness in the extremities in the treatment group were significantly superior to those in the control group (x2=10.16、7.37、5.63、4.29,P<0.05).ConclusionAt the same time of routine counter-shock therapy,thereby prompt burn patients to smoothly go through shock period and decreas late complications.
6.Virulence genes in multidrug resistant Escherichia coil
Yiping WANG ; Guozhong CHEN ; Yong LU ; Jianfei YING ; Yanhong YU ; Minfei AN ; Chengjie ZHOU ; Mingyang. HE
Chinese Journal of Clinical Infectious Diseases 2012;05(1):19-23
Objective To investigate the distribution of virulence-related genes in multidrug resistant Escherichia coli.Methods Seven virulence genes papA,cnf1,cnf2,cfaB,ipaB,hofQ and ompT were detected by PCR in 20 strains of multidrug resistant Escherichia coli clinically isolated,and the positive genes were further searched in 31 strains of Escherichia coli in BioCyc database whose genomies had been fully sequenced.Results Virulence genes hofQ and ompT were detected in 20 strains of Escherichia coli with a positive rate of 95.0% (19/20) and 55.0% ( 11/20),respectively.Among 31 strains of Escherichia coli in BioCyc,21 (67.7%) were positive for hofQ gene and 15 (48.4%) were positive for ompT gene.Conclusion hofQ and ompT genes are prevalent in multidrug resistant Escherichia coli.
7.Percutaneous transluminal angioplasty and vacuum sealing drainage for patients with diabetic foot and arteriosclerosis obliteration of the lower extremity
Guozhong JIANG ; Lei LI ; Weili LIU ; Jianfei ZHAO ; Fuqing WEI ; Kai LU
Chinese Journal of General Surgery 2016;31(4):293-296
Objective To study the clinical efficacy of percutaneous transluminal angioplasty (PTA) and vacuum sealing drainage technique on patients with diabetic foot and arteriosclerosis obliteration of the lower extremity.Methods Sixty-four patients were divided into two groups.Group A (32 patients) were treated by traditional methods,while 32 patients in Group B treated by vacuum sealing drainage technique in addition to percutaneous transluminal angioplasty.Results One week after surgery,ABI in group A was 0.53 ±0.17 vs 0.85 ±0.27 in group B,P =0.00.Ulcer healing rate increased from 31.25% in group A to 81.25% in group B,P <0.01.The amputation rate decreased from 56.25% in group A to 18.75% in group B,P =0.00.Claudication distance extended and ulcer recurrence rate in group A was 40%,while in group B it was 0,P =0.00.Conclusion The combination of PTA and vacuum sealing drainage significantly improves the prognosis of patients with diabetic foot and arteriosclerosis obliteration of the lower extremity.
8.Impact of medical staff loyalty on patient satisfaction:a study based on structural equation model
Yuezhou ZHU ; Pei WAN ; Xiang LU ; Guozhong JI ; Hui FU ; Wanwen DAI
Chinese Journal of Hospital Administration 2017;33(3):190-193
Objective To learn the relationship and operating mechanism between medical staff's loyalty and patient satisfaction.Methods Medical staff and inpatients of a tertiary hospital in Nanjing were sampled at a 1:2 ratio for study,with 840 questionnaires released and 269 valid questionnaires recovered;medical staff service quality as perceived by inpatients served as the intermediate variable,with Mplus7.0 used to build a structural formula model for an empirical study of the relationship between staff loyalty and patient satisfaction.Results Staff loyalty exerts certain positive influence on patient satisfaction and staff service quality ( P < 0.001 ); service quality also exerts some positive influence on patient satisfaction (P<0.001);staff loyalty indirectly exerts positive influence(P<0.001)via the service quality as perceived by patients(mediation effect value 0.364 > direct effect value 0.143).Conclusions Structural formula model can reveal the relationship and extent of the influence of staff loyalty on patient satisfaction.This indicates that hospitals should enhance the loyalty,medical competence and communication skills of their medical staff for higher patient satisfaction.
9.Physical fitness of four minority middle school students in Yunnan Province
Chinese Journal of School Health 2020;41(4):558-562
Objective:
To understand physical fitness of middle school students from 4 minorities in Yunnan Province and to provide the basis for the development of physical health promotion for minority middle school students.
Methods:
Data of physical fitness of students aged 13-18 years from the nationality of Jino, Lahu, Blang, Jingpo and Han in Yunnan Province collected during Sept. to Nov. of 2014 were analyzed. Comparative analysis was performed regarding body shape, function and quality indexes.
Results:
For total scores of physical fitness test, proportions of excellent and good scores were highest in the Jingpo nationality (10.8%, 57.7%), followed by the Jino nationality (6.7%, 57.4%), the Blang nationality (3.0%,30.3%) and the Lahu nationality (0.9%, 15.9%); proportions of excellent and good scores in boys were highest in the Jingpo nationality (20.1%, 54.0%), followed by the Jino nationality (6.4%, 43.9%), the Blang nationality (5.0%, 29.8%) and the Lahu nationality (1.5%, 18.1%); for girls, highest in the Jino nationality (7.1%, 71.1%), followed by the Jingpo nationality (2.4%, 61.0%), the Blang nationality (1.5%, 30.7%) and the Lahu nationality (0.5%, 14.4%). When compared with students from the Han nationality (5.1% excellent, 40.0% good), the Jingpo nationality and the Jino nationality showed higher overall scores while the Blang nationality and the Lahu nationality showed lower overall scores(Z=9.50,11.92,-11.54,-28.34,P<0.01).
Conclusion
Significant differences in physical fitness are observed in students with different minority background. Targeted measures should be proposed to promote physical health for minority students.
10.Correlation of right ventricular wall fatty infiltration or fibrosis degree and function and volume of right ventricle in arrhythmogenic right ventricular cardiomyopathy
Guozhong LI ; Jun PANG ; Fuhai WANG ; Minjie LU
Chinese Journal of Medical Imaging Technology 2018;34(5):678-682
Objective To investigate the correlation of right ventricular wall fatty infiltration or fibrosis degree and function and volume of right ventricle in patients with arrhythmogenic right ventricular cardiomyopathy (ARVC).Methods Twenty ARVC patients were enrolled.Multi-sequences of MR scanning were performed,and the transverse diameter of outflow tract of right and left ventricle,end-diastolic dimension (EDD),ejection fraction (EF),end-diastolic volume index (EDVI),end-systolic volume index (ESVI),cardiac output index (CI),as well as right ventricular myocardial mass index (MASSI) and fat and fibrosis tissue characteristics were quantitatively evaluated.The correlation between right ventricular wall fatty infiltration or fibrosis and right ventricular function and volume were analyzed.Results The right ventricular outflow tract transverse diameter was (52.42±11.80)mm,and right ventricular EDD,EF,EDVI,ESVI,CI and MASSI was(50.13 ± 8.71) mm,(18.13± 6.71)%,(169.13 ± 72.11) ml/m2,(117.01 ± 67.31) ml/m2,(1.81±0.20) L/(min · m2) and (17.62 ±1.80)ml/m2,respectively.The right ventricular free wall/anterior wall involvement was observed in all 20 cases,while inferior wall involvement,apical involvement and right ventricular outflow tract involvement was noticed in 10,14 and 15 cases,respectively.The right ventricular wall fat infiltration or fibrosis index was (70.00±22.33) %,correlated with right ventricular EF (r=-0.627,P =0.003),EDVI (r=0.695,P=0.001)) and ESVI (r=0.676,P=0.001).Conclusion The correlation of right ventricular wall fatty infiltration or fibrosis degree and function and volume of right ventricle may reflect changes of cardiac function in ARVC patients.