1.Study on Iron,Zinc,Copper,Manganese and Selenium Contents in Serum of Patients Suffering From Acute Myocardial Infarction and Using Thrombolysis Therapy
Xiaolin GUO ; Guozhen MA ; Meilan ZHANG
Journal of Chinese Physician 2002;0(S1):-
By using thrombolysis therapy,34 patients suffering from acute myocardial infarction were treated.And by comparing iron.zinc,copper,manganese and selenium contents in serum of 34 patients suffering from acute myocardial infarction with that of control group and the contents between before-treating and after-treating,following results are revealed:before treating,iron,zinc,copper contents in serum of the patients increased while manganese and selenium contents decreased,there is great difference between the contents of the patients and control group(P
2.Family factors influencing dietary behavior of primary and secondary sch ool students in Guangzhou city
Wenjun MA ; Lin DU ; Guozhen LIN ; Yaqi REN ; Guansheng MA
Chinese Journal of Disease Control & Prevention 2001;5(2):125-127
Objective The purpose of the study was to explore influence of family factors on dietary behavior of primary and secondary studen t s in Guangzhou city, in order to provide suggestions for intervention of dietary behavi or. Methods The study population included 1 539 student-parent s pairs selected from Guangzhou city by using the method of stratified multistage cluster random sampling, and data were collected through questionnaires. Results The ratio of parents who often reminded and forced the ir children to eat some fo od they thought of as nutrition were 56.0% and 7.7%, and 39.7%, 29.2% of ch ildren complied with their parents, respectively. At dinner, 14.8% and 27.5% of parents often and sometimes criticized their children, and the ratio of childre n couldn't eat anything and only eat a little food were 5.9%,19.3%, respectively . Forty-two point three of primary and secondary school students watched televi sion wh en they had a dinner, which made 39.4% of students not eat seriously. C onclusions Dietary behavior of primary and secondary school students is influenced strongly by their parents and family environment, it is necessary for parents and themselves to grasp enough nutritional knowledge.
3.Effects of two methods for deep endotracheal sputum suction
Guozhen MA ; Shouzhen CHENG ; Pengjun JIANG ; Chun ZHONG ; Yongzhi DING
Modern Clinical Nursing 2014;(4):17-19
Objective To explore the effects of two methods for deep endotracheal suction.Methods Forty patients who had ineffective airway clearance or lung infections or refused suction were randomly divided into observation group (n=21) and control group (n=19).Temporay airway was established by using oropharyngeal airway.Then,the control group received subglottic suction after pading the shoulder with ordinary pillow (≤10cm),while the observation group received subglottic suction after pading the shoulder with homemade pillow (=15cm).The two groups were compared in terms of sputum suction effect and mucosal injury.Results There was no incidence of mucosal injury in the observation group but three in the control group.The times of suctioning in the observation group were fewer than those of the control group and the volume for suctioning was larger as well (allP<0.05).Conclusion Deep endotracheal suction through oropharyngeal airway,shoulder elevation for 15cm,temporary indwelling of suction tubes can achieve better suction effect without corresponding complications.
4.Effect of health education improvement on promotion of timely vaccination among migrant children in community
Guozhen MA ; Beirong MO ; Pengjun JIANG ; Honglin SHEN ; Junmei DENG
Chinese Journal of Nursing 2017;52(1):87-92
Objective To explore the effect of health education improvement on promotion of timely vaccination among migrant children in community and to provide references for community health service center.Methods A total of 155 migrant children's parents were recruited from July 2015 to February 2016,and improved health education intervention was carried out on the basis of routine health education to promote parents' health belief on timely vaccination.The compliance of parents' participation in health education activities,the health belief of parents themselves on timely vaccination at different stages of intervention and parents' satisfaction,and the rate of timely vaccination of migrant children before and after intervention were evaluated.Results Regarding the compliance of health education activities for parents in 12 weeks,the first 3 weeks was 85% ~ 91%,the last 4 weeks were 95% and above.Six months after intervention,the score of parents' health belief on timely vaccination was higher than that after 3 months of intervention and before intervention,and the difference was statistically significant (P<0.05).The timely vaccination rates in the study group for migrant children was higher than that in the historical groups (P<0.05).After intervention,the satisfaction rate for parents was 95.484%.Conclusion Health education improvement could effectively promote parents' health belief on timely vaccination,satisfaction rate and rate of timely vaccination among migrant children.
5.Dynamic Contract-Enhanced MRI Study of Perfusion Change in SHCC
Suhua GOU ; Guozhen QING ; Hanbin DONG ; Daguang SHEN ; Qinhua MA
Journal of Practical Radiology 2001;0(05):-
Objective To study the manifestations of perfusion change in small heptic cell cancer(SHCC) on dynamic contract-enhanced MRI. Methods 18 cases of SHCC(21 lesions) proved by pathology were presented. Dynamic contrast-enhanced MRI was performed using 2D T_1-turbor-FLASH sequence for 18 SHCC.Results Among all 18 cases of SHCC, 17 cases were obvious enhanced, and one case was no enhancement. In 17caese of enhanced tumors, the maximal peak of enhancement was in the first set (6~23 s) in 2 cases and in the second set (33~51 s) in 15 cases. The average maximal peak of contrast-enhanced time was 42.5 s(23~50.5 s),and the average maximal peak of signal intensity increased up to 30.5 (19.5~45.0). The pattern of time-intensity curve was rapid wash-in followed by washout in 17 cases.Conclusion Dynamic contract-enhanced MRI is important on study and diagnosis of SHCC.
6.Effects of active ingredients from Coleus forskohlii on human neutrophil
Xiaoning PEI ; Chen QING ; Guozhen CHEN ; Yunlong XU ; Qiduan JING ; Limei MA ; Weimin YANG
Chinese Journal of Emergency Medicine 2008;17(12):1266-1270
Objective To study the effect of plant Coleus forskohlii active elements Isoforskolin(ISOF)and CT-E(analogs mixture of Isoforskolin)on human neutrophill(PMN)in vitro in order to uncover the mechanism of their properties of mitigating acute lung injury(ALI).Method The effects of ISOF and CF-E on PMN aggregation induced by N-formyl-methiony-leucyl-phenylalanine(fMLP)was performed by using a 4-channel platelet aggregometer.Cytometry Was applied to analyze the effect of tested samples on adhension between PMN and endothelial cells(ECV-304)activated by using lipopolysaccharides(LPS).Expression of LPS-induced PMN adhension molecules was determined with flow cytometry.Radioimmunoassay Was applied to detect the level of TNT-α liberated bv PMN and intracellular cyclic adenosine monophosphate(cAMP)level of PMN.Results It was found that ISOF(25,50,100 μmnol/L)and CF-E(1.25,2.5,5 mg/ml)inhibitted PMN aggregation induced by fMLP,PMN adhemion to ECV-304 indeed by LPS,expression of PMN adhesion molecules,and TNF-α level released by PMN.ISOF and CF-E also increased intracellular cAMP level of PMN.Condusions ISOF and CF-E inhibit PMN aggregation,adhension and adhension molecules,and TNF-α released by PMN,while they increase intracellular cAniP level of PMN.It suggests that their specific alleviating the ALI by the mechanism of the modulation of PMN function.
7.Assessment of diagnostic value of human epididymis secretory protein versus CA125 for endometrial cancer
Jinghua LI ; Tie ZHANG ; Guozhen WANG ; Haibo MA ; Xinhui JING ; Yongtong CAO
Chinese Journal of Geriatrics 2014;33(5):514-517
Objective To assess the diagnostic value of human epididymis secretory protein (HE4) versus CA125 for endometrial cancer.Methods Serum HE4 and CA125 levels were measured by enzyme-linked immunosorbent assay (ELISA) and electrochemiluminescence immunoassay (ECLI) in 35 patients with endometrial cancer,48 patients with benign endometrial disorders and 40 healthy controls.The best cutoff value,sensitivity and specificity were calculated with pathological results as golden standard.Receiver operating characteristic curves were plotted,and areaunderthecurve (ROC-AUC) was used to compare diagnostic value of HE4 and CA125.Results The median value in HE4 in endometrial cancer were 51.46 pmol/L,which was significantly higher than in the healthy and benign disorder controls (25.65 pmol/L and 27.92 pmol/L).However,CA125 levels did not show statistically significant difference among the 3 groups.The ROC-AUC of HE4 for discriminating endometrial cancer between healthy controls and benign disorder controls were 0.922 and 0.759,respectively,which showed higher diagnostic value than CA125 (ROC-AUC of 0.590 and 0.457,respectively).HE4 had a specificity/sensitivity of 87.5% /86.1% for distinguishing healthy controls from endometrial cancer,and 95.5% /50% for differential diagnosis with benign disorders.Conclusions Measurement of HE4 can be used as a tumor marker for diagnosis of endometrial cancer.
8.Relationships between nutrition status, sleep quality, anxiety and depression in patients with chronic heart failure
Yuanyuan CHEN ; Guozhen SUN ; Xiaoran MA ; Wei YAN
Modern Clinical Nursing 2017;16(10):12-16
Objective To investigate the nutrition status, sleep quality, anxiety and depression in patients with chronic heart failure (CHF), and to analyze the relationships between them. Method Hospital anxiety and depression scale (HADS), mini nutritional assessment (MNA) and Pittsburgh sleep quality index (PSQI) were used to assess anxiety and depression, nutrition status and sleep quality in 118 CHF patients who were selected by convenience sanpling respectively. Results The score of anxiety of the patients was with a median of 5 (3, 8) and the score of depression was with a median of 5 (2, 8). Anxiety was present in 47 cases (39.8%). Depression was present in 48 cases (40.7%).MNA score was with an average of 21.5 ±3.5, 19 patients (16.1%) were malnourished, 59 patients (50.0%) were at risk of malnutrition and 40 (33.9%)well nourished. The MNA scores of patients with anxiety or depression were significantly lower than those with no anxiety or depression (P<0.001). The PSQI score in 118 patients was 6(4, 10), where 42(35.6%) were with sleep disorder and patients with depression and anxiety were higher than those without (P<0.01). The MNA score was negatively correlated with anxiety and depression (all P<0.001). The PSQI score was positively related with anxiety and depression (all P<0.01). Conclusions The prevalence of anxiety and depression was high in CHF patients. Both nutrition status and sleep quality were related to them. In the clinic work, medical workers should pay attention to the treatment of heart failure and the assessment of psychological status in heart failure patients with malnutrition or sleep disorders.
9.A retrospective study of the treatment for epithelial-myoepithelial carcinoma
Jianghu ZHANG ; Xiaodong HUANG ; Li GAO ; Junlin YI ; Lin YANG ; Peiqing MA ; Guozhen XU ; Jingwei LUO ; Jiangping XIAO ; Kai WANG ; Yuan QU ; Shiping ZHANG
Chinese Journal of Radiation Oncology 2017;26(5):513-516
Objective To evaluate the risk of locoregional recurrence (LRR) and the influencing factors for long-term survival in patients with epithelial-myoepithelial carcinoma (EMCa).Methods A retrospective analysis was performed for 18 EMCa patients, who received initial therapy or initial adjuvant therapy in our hospital from 1999 to 2015, to investigate their survival.Among these patients, 8(44%) underwent surgery alone, 9(50%) received adjuvant radiotherapy, and 1(6%) received radical concurrent chemoradiotherapy.Locoregional recurrence-free survival (LRFS) and overall survival (OS) rates were compared between these groups.The Kaplan-Meier mtthod was used to calculated survival rates and log-rank test was used to compare the LRFS.Results With a median follow-up time of 46 months, 5 patients developed LRR, and the 5-year LRFS and OS rates were 69% and 93%, respectively.The patients treated with radiotherapy had a significantly higher 5-year LRRFS rate than those not treated with radiotherapy (71% vs.57%, P=0.569).Conclusions LRR is the main failure mode of EMCa treatment, and further improving local control is the key to improved survival.
10.Impact of air temperature on years of life lost among residents in Guangzhou and Zhuhai:a ;time-series study
Zhihao LI ; Yanjun XU ; Guozhen LIN ; Deyun LI ; Tao LIU ; Hualiang LIN ; Jianpeng XIAO ; Weilin ZENG ; Xing LI ; Wenjun MA
Chinese Journal of Epidemiology 2015;(7):720-724
Objective To evaluate the impacts of air temperature on years of life lost(YLL) among the residents in Guangzhou and Zhuhai,Guangdong province. Methods Daily mortality and meteorology data in Guangzhou and Zhuhai were collected,and distributed lag non-linear model (DLNM)was used to evaluate the cumulative and delayed effects of daily air temperature on YLL of total non-accident mortality. The accumulative effect of air temperature on mortality under the extreme high temperature(0-1 days)and extreme low temperature(0-13 days)situation in Guangzhou and Zhuhai were analyzed respectively. Results The average YLL was 1 928.0 in Guangzhou and 202.5 in Zhuhai. The exposure-response functions seemed to be non-linear. The hot effect seemed to be acute and reached the peak at the same day,while the cold effect reached the peak at 5th days and lasted for about two weeks. Low temperature had stronger gross effect than high temperature had. The cold effect among males was greater than that among females in Guangzhou. The hot/cold effect on YLL was greater in people aged ≥65 years than in people aged <65 years and in people suffering from respiratory disease than in people suffering from cardiovascular disease in both Guangzhou and Zhuhai. Conclusion The effects of high and low temperatures on YLL were obvious,and the impact of low temperature was greater. The elderly and people suffering from respiratory disease or cardiovascular disease are the vulnerable populations.