1.Education of Unergraduates of Exercise Rehabilitation in China: in Perspective of ICF
Chinese Journal of Rehabilitation Theory and Practice 2015;21(9):1002-1005
Based on International Classification of Functioning, Disability and Healthy (ICF), this paper discussed the education of exercise rehabilitation in the terms of the goal, knowledge system and practice system. It suggested that the framework of ICF could be used to develop course system. The professional undergraduate education of exercise rehabilitation should include knowledge of rehabilitation medicine, sports science, and skills in modern rehabilitation.
2.Mediastinal Tumors:Imaging Characters
Journal of Practical Radiology 2001;0(10):-
Objective To study the value of imaging characters in diagnosing mediastinal tumors.Methods X-ray and CT findings of pathologically proved mediastinal tumors in 58 cases were analysed,the findings enabling qualitative diagnosis were recommended. Results There were 40 cases of anterior mediastinal tumors including intrathoracic thyroid tumors [n=32,5 tyroid carcinomas and 1 thyroid cyst ,thymomas (n=3) and teratomas (n=5, 3 cases ruptured)]. All the other 18 cases in posterior mediastinum were neurogenic tumors.Conclusion Based on the combination of the mediastinal compartment knowledge, X-ray and CT findings of the tumors and the clinical information, the qualitative diagnosis of mediastinal tumors will be characterized correctly.
3.Study on Mechanism of Activities of Gastric Alcohol Dehydrogenases before and after Abetiuence of Alcohol.
Guoxiang WANG ; Xuqing ZHU ; Xin ZHANG
Journal of Medical Research 2006;0(01):-
Objective To study the mechanism of activity change of gastric alcohol dehydrogenases(ADH).We investigated ADH before and after ingestion of alcohol on rats.Methods Thirty-nine rats were divided into two groups at random:model ones(24 cases) and control ones(15 cases).Model group of rats were infused into stomaches by alcohol,and control ones by distill water.Structures of cell and sub-cell in gastric mucous membrane were observed by enzyme electron microscope and hematoxylin eosin(HE) stain.Results It was shown that there were dropsical degeneration of chief cells and parietal cells of stomaches by HE stain,and the mitochondria of parietal cells and the rough-surfaced endoplasmic reticulum(rER) of chief cells were destroyed by enzyme electron microscope in model groups after two months of ethanol perfusion.There were not change in control group.Conclusions The mechanism of activity alterations of gastric ADH may result from dropsical degeneration of chief cells and parietal cells of stomach,which result in degeneration,solution and breakage of construction of rER in the chief cells and mitochondria in parietal cells.
4.Roles of epithelial CTGF expression in airway remodeling in asthmatic rats
Guoxiang LIU ; Lei ZHANG ; Ying HUANG ;
Journal of Third Military Medical University 2003;0(20):-
Objective To investigate the roles of connective tissue growth factor(CTGF) in airway remodeling in asthmatic rats by observation of the changes of CTGF expression in the lungs of asthmatic rats. Methods Rats were sensitized and challenged continually with ovalbumin(OVA) for the purpose of induction of asthma in rats. The distribution and types of collagens were detected by Cirius red staining. Lung hydroxyproline content was determined by acid hydrolysis. CTGF expression in rat pulmonary tissues was detected by SABC immunohistochemistry. Results After continual challenging with OVA for 21 days, collagen hyperplasia was found in the airway wall and CTGF positive expression in airway epithelium. CTGF expression was closely associated with lung hydroxyproline content ( r =0.63, P
5.Sympathectomy for Raynaud disease
Guoxiang DONG ; Nengwei ZHANG ; Jun ZHAO
Chinese Journal of Minimally Invasive Surgery 2001;0(01):-
Objective To study the effect of thoracoscopic sympathectomy and/or chemical lumbar sympa- thectomy performed on patients with Raynaud disease. Methods Five patients, 1 male,4 females, aged from 30 to 65(mean 45. 3 ). Raynaud phenomenon appeared only on both hands in one patient, only on feet with a toe gangrene in another one , the other 3 cases on all limbs. Thoracoscopic symathectomy was performed for those whose hands were af- fected and chemical lumbar sympathectomy(12-3 ) was pererformed for those whose feet were affected. Results All patients were followed up from 12 to 48 months(mean 24 months). All experinced improvement with hands warm and satisfactory results after thoracoscopic sympathectomy. However, the original symptoms reccurred in two patients after postoperatire six months. All 4 patients performed chemical lumbar sympathectomy experienced improved symptoms with feet warm and satisfactory results and the symptoms did not recur up to now. The sympathectomy showed different results for hands and for feet. Conclusions Thoracoscopic sympathectomy for hands affected by Raynaud disease has efficiency temporarily, but is not satisfactory. The chemical lumbar sympathectomy for the feet affected by Raynaud disease has dramatically disappearence of symptoms and the results are very good
6.IL-1?,mIL-2R and IL-10 Levels in Peripheral Blood from Patients with Chronic Hepatitis B:Detection and Significance
Wenlong XU ; Guoxiang ZHANG ; Hongqi WANG
Chinese Journal of Nosocomiology 2006;0(07):-
OBJECTIVE To explore the relationship between cytokines(IL-1?,mIL-2R,IL-10) and hepatatis B virus(HBV) serum markers in patients with chronic hepatitis B(CHB).METHODS The serum level of IL-1?,mIL-2R and IL-10 in 65 patients with CHB was measured with chemiluminescence immunoassay(CLIA).RESULTS Of the patients with positive and negative HBeAg,the serum IL-1? and IL-10 levels were significantly higher than normal controls(P
7.Risk factors and association between cardio-ankle vascular index and carotid atherosclerosis in the patients with type 2 diabetes mellitus
Guoxiang TIAN ; Ling ZHANG ; Wei ZHANG ; Wanlin WEI
Clinical Medicine of China 2012;28(1):28-31
ObjectiveTo study the association between cardio-ankle vascular index (CAVI) and carotid atherosclerosis as well as the risk factors in patients with type 2 diabetes mellitus.MethodsSixty type2 diabetic patients and 60 non-diabetic patients at the same hospitalization period were selected.The clinical features,laboratory test results such as free blood glucose ( FBG),blood lipids and other biochemical markers were recorded.Carotid intima-media thickness (IMT) and CAVI were measured.The relationship between CAVI and carotid atherosclerosis were analyzed; a multivariate linear regression analysis was performed between CAVI and risk factors of type 2 diabetes mellitus.ResultsThe body mass index,triglycerides,FBG,HbA1 c,IMT,the incidence of carotid artery plaque and CAVI values of diabetic group were significantly higher than that of nondiabetic group.Difference between the two groups was statistically significant ( all P < 0.05 ) ; CAVI and carotid IMT was significantly correlated to each other( r =0.435,P < 0.01 ) ; Multiple linear regression analysis showed that CAVI was significantly correlated to age (β =0.458,P <0.01 ),triglycerides (β =0.058,P =0.012),FBG (β =0.168,P =0.002) and HbAlc (β =0.228,P =0.003).ConclusionCAVI inpatients with diabetes was positively correlated with carotid IMT.Age,diabetes,triglycerides,FBG and HbAlc are independent risk factors for arterial stiffness.
8.Plasma vitamin E and coenzyme Q10 levels and clinical significance in patients with autosomal recessive cerebellar ataxia
Xin ZHANG ; Weihong GU ; Guoxiang WANG ; Yuanyuan CHEN ; Jin ZHANG
Chinese Journal of Neurology 2016;49(6):463-466
Objective To analyze plasma vitamin E and CoQ10 levels in patients with autosomal recessive cerebellar ataxia for finding the evidence of the related pathogenesis research and therapeutic strategies.Methods The plasma vitamin E and CoQ10 levels were detected by high performance liquid chromatography (HPLC) with diode array detector in 123 probands of autosomal recessive cerebellar ataxia pedigrees.Quantitation was performed using vitamin E and CoQ10 external standard and two 5-point calibration curve;clinical manifestations were analyzed simuhaneously.Results Vitamin E and CoQ10 levels of healthy subjects in the plasma were (8.77 ± 2.28) μg/ml and (1.31 ± 0.38) μg/ml,respectively;the plasma vitamin E and CoQ10 levels of patients were (5.61 ± 2.04) μg/ml and (0.79 ± 0.26) μg/ml,respectively,which were significantly lower than those in healthy controls (t =11.87,13.15;all P< 0.01).Clinical manifestations were characterized by cerebellar symptoms,and gait instability was usually the first recognized abnormality.Most of early onset occurred before the age of 25 years (111/123);dysarthria and abnormal eye movement were observed,with cerebellar atrophy on MRI;concomitant symptoms were also present.Conclusions HPLC analysis shows that the plasma vitamin E and CoQ10 levels of patients with autosomal recessive cerebellar ataxia are generally lower than those in the healthy controls.Several patients with significant reductions in these two levels have genetic defects.The combination of clinical phenotypes,biochemical indexes and genetic analyses will be helpful for the establishment of diagnosis and specific treatment.
9.International academic conference promotes innovation in scientific research
Zongtao CHEN ; Dongxu ZHANG ; Dixiong XU ; Guoxiang LIU
Chinese Journal of Medical Science Research Management 2011;24(4):266-268
International academic conference is important for universities to participate in international cooperation and exchange. The several large-scale international conferences on military medicine held by the Third Medical Military University opened up international exchange in basic medical science, clinical medicine, military medicine, etc. We have adopted a diversity of means, such as taking initiative to hold international conference, facilitating conferences that conform to the current scientific trend and making use of all possible resources to gain the opportunities for holding the international conferences. As a result, we succeeded in absorbing the latest information in science and technology, building up academic reputation, promoting international cooperation, accelerating the training of personnels, creating a good atmosphere for international exchanges, et al.
10.Research on RCD of burned rats based on model of silicon microchannels-capillary
Wenxian ZHANG ; Xiaolin ZHENG ; Yanjian LIAO ; Chenglin PENG ; Guoxiang HE
Chinese Medical Equipment Journal 2003;0(12):-
The red cell deformability (RCD) has been taken as a diagnostic aid in recent years. The dilute red cell suspension passes through the silicon microch annels under constant suction pressure. Such three parameters of RCD are measure d as IF (filtration index), and The results show that the above-mentioned parameters can reflect the changes of cell rheological characteristics from dif ferent aspects. With the observation of the flow passage, the rehological charac teristics can be evaluated accurately and comprehensively.