1.The application of the new assistance chemotherapy in breast cancer
Chinese Journal of Primary Medicine and Pharmacy 2010;17(22):3072-3073
Objective To summarize the application of new assistance chemotherapy(NCT) in the surgeriable breast cancer,to study the security of NCT in the near future curative effects and the influence to surgery way.Methods The clinical date of 36 cases with Ⅰ~Ⅲ breast cancer were retrospectively analyzed. Results There are 8 examples of CCR, 19 examples of CPR,3 examples of PCR in the total cases. The total effective rate is 83.3%.There is no obvious side reaction. Conclusion As a result of the safety and effectiveness, NCT is an important way for treating breast neoplasms.
2.A study of the effects of auricular point plaster therapeutic time on pain caused by cyclomastopathy
Chinese Journal of Primary Medicine and Pharmacy 2015;(5):670-672,673
Objective To observe the effects of auricular point plaster therapeutic time on pain caused by cyclomastopathy .Methods 90 patients who visited breast surgery outpatient clinic and were diagnosed as cyclomas -topathy due to stagnation of liver -QI were randomly divided into the three groups by numerical table:3 days ( group A),5 days(group B),7 days(group C) ear acupoint therapy group,30 cases each.Improved pain symptoms of cyclo-mastopathy were compared among the three groups .Results There was statistical significance to reduce pain symp-toms in the three groups[before the treatment:(4.57 ±1.74)points,(4.63 ±1.83)points,(4.81 ±1.57)points;after the treatment:(3.45 ±1.52)points,(1.82 ±0.96)points,(2.45 ±1.03)points.t=2.66,7.45,6.88,all P<0.05].There was obvious statistical difference between group B and group C (t=7.45,6.88,all P<0.01),and low recurrence rate .Conclusion 5 days auricular point plaster therapy is worthy of clinical popularization because which can improve pain symptom of cyclomastopathy ,shorten time of therapy with high compliance and low recurrence rate .
3.Several reflections on the legislation of euthanasia in China
Chinese Journal of Hospital Administration 1996;0(01):-
Euthanasia, which involves medicine, law, sociology, philosophy, ethics and various other aspects, has become a universal issue. With social progress and development, people have come to focus their attention not only on eugenics but also on euthanasia. The paper analyzes the issue of euthanasia legislation in China from six aspects, including the principles of law, ethics and the significance of adopting euthanasia.
4.Nursing of three patients with continuous ambulatory peritoneal dialysis complicated by abdominal fistula
Modern Clinical Nursing 2015;14(9):65-67
Objective To investigate nursing of patients with continuous ambulatory peritoneal dialysis (CAPD) complicated by abdominal fistula. Methods Three patients with CAPD complicated by abdomial fistula who were treated in the nephrology department from January 2013 to September 2014 were nursed, including disease observation, chest drainage, measurable CAPD and health education. Result Two patients eventually turned to hemodialysis and 1 cases took pleural elemene injection 20 mL +lidocaine 5 mL, suspended peritoneal dialysis for 4 weeks to continue to receive the peritoneal dialysis treatment. Conclusions Abdominal fistula can be detected early based on clinical manifestations. Doctors and nurses in coordination, early treatment can reduce the pain of patients and the occurrence of complications.
5.Quality Evaluation of Yinhuang Tablets via Digitized and Quantified Fingerprints by High Performance Liquid Chromatography and Seven Components Detection
Herald of Medicine 2015;(3):371-376
Objective To establish the quality control of Yinhuang tablet (YHT) by using sever ingredients determina-tion and tri-wavelength fingerprint analysis technologies. Methods The chromatographic fingerprints were developed by using Agilent Poroshell 120 SB C18(4. 6 mm×150 mm, 2. 7 μm) as the separation column and 0. 2% H3 PO4-methanol as the mobile phase. The flow rate was 0. 5 mL·min-1 , the UV absorbance was monitored at 214, 278 and 326 nm by injecting 5 μL of the sample solution and the column temperature was maintained at (35. 00±0. 15) ℃ . The chromatographic fingerprints were charac-teristically evaluated for quality ranking of 13 batches of YHT by the 4. 0 software of the digitized evaluation system of traditional chinese medicine fingerprint with the super information characteristics. Seven marker compounds including chlorogenic acid, caf-feic acid, baicalin, wogonoside, baicalein, wogonin and scutellarin were simultaneously determined to compare the variation a-mong five different manufacturers. Results The tri-wavelength fingerprint high performance liquid chromatography method was established. A total of 28(214 nm),29(278 nm)and 26(326 nm)common peaks were identified at respective wavelengths, using baicalin (BCL) as the referential peak. The software was applied to evaluate the YHT-HPLC fingerprints and identify the quality of 13 batches of YHT by systematically quantified fingerprint method (SQFM). The results showed that the content from the dif-ferent manufacturers varied greatly. Conclusion The quality of YHT varies between different makers, and is necessary to es-tablish the criterion for quality control. This method can provide a new reference for the quality control of YHT.
6.Effects of taurine on platelet aggregation induced by benzo pyrene in vitro activation function
Acta Universitatis Medicinalis Anhui 2015;(1):116-118
The peripheral renous blood which were taken from healthy volunteers and platelet was isolated. Platelet samples were randomly divided into six groups. The effects of different concentration of taurine( Tau) on benzo py-rene( BAP) induced platelet aggregation in vitro activation function were investigated by detecting the maximum platelet aggregation rate, the positive expression rates of platelet membrane surface CD62P and PAC-1. The results showed that platelet maximum aggregation rate had significant differences between each concentration of BAP-Tau groups and solvent control group in adenosine diphosphate(ADP) and collagen induced (P<0. 01). The positive expression rates of platelet membrane surface CD62 P and PAC-1 in BAP-Tau high concentration group had signifi-cant differences compared with solvent control group ( P<0. 01 ) . Different concentration of Tau could antagonize platelet function damage induced by BAP with a concentration gradient change.
7.The de-escalation therapy combined bronchoalveolar lavage in treatment of acute stroke complicate pulmonary infection
Chinese Journal of Practical Internal Medicine 2006;0(21):-
Objective To evaluate the effect of the de-escalation therapy of antimicrobial agents combined bronchoalveolar lavage on the treatment of acute stroke complicate pulmonary infection.Methods 80 patients of acute stroke complicated pulmonary infection were randomized into two groups.The method of the de-escalation therapy of antimicrobial agents combined bronchoalveolar lavage was used in therapeutic group(n=40)while the patients in control group(n=42)received routine therapy of antimicrobial agents.The effective rate,the bacteria1 eradication rat,the average time of pneumonia absorption and the average time NICU stay between two groups were compared and analyzed.Results The effective rate and the bacteria1 eradication rat in therapeutic group were significantly higher than those in control group(P
8.Medical rescue and emergency management of natural disasters
Guoxiang ZHAO ; Shengyong WANG
Chinese Journal of Disease Control & Prevention 2008;0(05):-
China is one of the countries with most serious natural disasters lose all over the world.Natural disasters are a public emergency.Human society can't avoid the natural disasters today,so the global target of a struggle is to reduce the loss of natural disasters.The natural disasters loss will be reduced to a minimum,once the system is established of medical rescue and emergency management by the government.
9.Mediastinal Tumors:Imaging Characters
Journal of Practical Radiology 2001;0(10):-
Objective To study the value of imaging characters in diagnosing mediastinal tumors.Methods X-ray and CT findings of pathologically proved mediastinal tumors in 58 cases were analysed,the findings enabling qualitative diagnosis were recommended. Results There were 40 cases of anterior mediastinal tumors including intrathoracic thyroid tumors [n=32,5 tyroid carcinomas and 1 thyroid cyst ,thymomas (n=3) and teratomas (n=5, 3 cases ruptured)]. All the other 18 cases in posterior mediastinum were neurogenic tumors.Conclusion Based on the combination of the mediastinal compartment knowledge, X-ray and CT findings of the tumors and the clinical information, the qualitative diagnosis of mediastinal tumors will be characterized correctly.
10.Determination of the four components in Ginkgo-Leaf-Extract Dipyridamole Injection by HPLC
Chinese Traditional Patent Medicine 1992;0(11):-
AIM: To simutaneously determinate the four components of dipyridamole, quercetin,kaempferol and isorhamnetin in Ginkgo-Leaf-Extract Dipyridamole Injection by the reversed-phase high performance liquid chromatographic (RP-HPLC). METHODS: Ginkgo-Leaf-Extract Dipyridamole Injection was determined by RP-HPLC on Scienhome Kromasil C_ 18 (250 mm? 4.6 mm, 5 ?m) column. The mobile phase consisted of methanol and 0.4% phosphoric acid solution (55∶ 45, v/v), the flow rate of 0.80 mL/min and UV detection wavelength at 360 nm were set to determine the contents of the four components. RESULTS: There were good linear relationships between peak area and concentration of the four components, and the calibration curves were linear in the ranges of 21.7 -261.0 ?g/mL for dipyridamole, 8.0 -96.0 ?g/mL for quercetin, 7.75 -93.0 ?g/mL for kaempferol, 5.75 -69.0 ?g/mL for isorhamnetin. The precisions for dipyridamole, quercetin, kaempferol and isorhamnetin were 1.16% , 1.35% , 1.21% and 1.58% , respectively. The average recoveries were 100.3% , 100.0% , 99.86% and 99.80% , respectively. CONCLUSION: The four components of the dipyridamole, quercetin, kaempferol and isorhamnetin in Ginkgo-Left-Extract Dipyridamole Injection are determined at the same time, and the method is simple, sensitive and accurate.