2.PAY MORE ATTENTION TO THE RESEARCH ON WAR INJURIES IN TROPICAL REGION
Medical Journal of Chinese People's Liberation Army 1981;0(04):-
The research on war injuries in tropical areas is an important subject to be urgently dealt with at present in Chinese military medicine. Military medicine related to hot and humid environment is a significant branch of military environmental medicine. More efforts should be made in the research on care of war injuries as well as on military hygiene and military epidemiology so as to establish an integrated system involving basic and clinical science and art in military environmental medicine in hot and humid areas, which should be considered as an important task in the transition of our military strategy to win a war with improvement in the military medical support capability in a local high technicology conflict in such an area. In this paper, the significance of paying more attention to the research on the care of war injuries in hot and humid areas is emphasized, their features are highlighted, and main problems demanding further research are proposed.
3.CHANGES OF SOME CARDIAC PARAMETERS IN PATIENTS WITH PROLACTINOMA
Chinese Journal of Endocrinology and Metabolism 1986;0(03):-
normal value in 11 cases .All cases were young women without hypertension, coronary heart diesease, valvular heart disease, hyperthyroidism,, acromegaly, etc., and were followed up for 2 years after adenomectomy. In 14 cases with PRL
4.Tendency and strategy of tissue engineering in the 21th century
Chinese Journal of Orthopaedic Trauma 2004;0(07):-
With 20 years’ development, tissue engineering has proceeded to a new stage where the focuses of research are quite different from those at the initial stage. Clinical application and industrial development have been the chief concerns for tissue engineering. After brief comments on the current advances and future prospects, this paper suggests that the future tendencies and strategies will be the primary clinical application, industrial development of tissue engineering products, increasing integration of basic research and clinical application and industrial development, construction of bionic and intelligent tissues or organs, and reliability evaluation. This paper also puts forward some strategies.
6.THE STATUS QUO AND TENDENCY OF BONE TISSUE ENGINEERING RESEARCH
Medical Journal of Chinese People's Liberation Army 1981;0(06):-
Bone tissue engineering is the focus of recent research. Its status quo and tendency are discussed from scaffold, cell and tissue reconstruction. Based on this analysis, we want to shorten the distance before it's clinical application and give some reasonable methods.
7.Tissue engineering: opportunity and challenge in the 21st century
Chinese Journal of Orthopaedic Trauma 2002;0(01):-
Tissue engineering has been one of the most challenging and rapidly developing frontier fields of science in the recent 20 years. Being referred to as “a medical revolution of far-reaching significance”, “a new epoch of regenerative medicine”, it signals the coming of a period of reproduction of regenerative tissue and organs. It has drawn intensive attention and support from medical circles and governments all over the world because of its advantages in trauma repair, functional reconstruction, life saving and improving quality of life, as well as its huge social and economic values. Products of tissue engineered skin and cartilage with approval of the American FDA have been available. Hundreds of tissue engineering companies and research centers have been set up both abroad and at home. It is now possible to construct tissue-engineered tissues. Moreover, projects of complex organ construction by means of tissue engineering is being carried out vigorously in the world. Some tissue-engineered tissues have been put into trial use in clinic and resulted in encouraging outcome. All these forecast a bright and promising prospect for tissue engineering. As a new branch of science and technology that involves multiple specialties and fields, however, it is still at its initial stage. Many fundamental scientific problems are to be explored, and many technical difficulties to be overcome. Hope and difficulty coexist; opportunity and challenge stand side by side. We should seize the opportunity and meet the challenge with our creative and strenuous efforts to make tissue engineering benefit human beings as early and much as possible.
8.Significance of the application of polylactic acid sustained-release scaffold
Chinese Journal of Tissue Engineering Research 2005;9(46):178-180
OBJECTIVE: Polylactic acid (PLA) is a biodegradable polymer possessing good biocompatibility and biodegradability, and approved as a biomaterial for in vivo implantation by American Food and Drug Administration (FDA). The role of cytokines in promoting osteogenesis and vascularization for constructing tissue-engineered bones has received increasing attention.But exogenous cytokine has shorter half-life in vivo and can not reach and maintain relatively high local level for bone repair. This article reviews the present researches and analyzes the application prospect of PLA and its derivatives in bone tissue engineering to serve as the carrier for polypeptide and protein medicines with controlled release through its degradation.DATA SOURCES: Related articles published between 1993 and 2004were searched in Medline database with key words of "polylactic acid,bone morphogenetic protein, vascular endothelial growth factor, TGF- beta", limiting the language to English; meanwhile the related medical papers between 1993 and 2004 were also searched in the Chinese Periodical Database, limiting the language to Chinese.STUDY SELECTION: Related researches on PLA and its derivatives for constructing bone tissue-engineering Scaffolds and study of PLA scaffolds carrying cytokines were included with the obsolete literature and repetitive researches eliminated.DATA EXTRACTION: Altogether 96 related literatures on PLA and its derivatives for constructing bone tissue-engineering scaffolds were collected, 23 of which were included in this review.DATA SYNTHESIS: PLA/PLA-polyglycolic acid copolymer is a good biodegradable scaffold for controlled drug release, having the dual functions as scaffolds and sustained-release drug carrier. PLA is the earliest scaffold material in bone and cartilage tissue-engineering, and also the most widely used tissue-engineering material at present. BMP is the most frequently adopted cytokine in bone tissue-engineering, and PLA scaffolds carrying sustained-release BMP is studies most thoroughly, but researches on PLA scaffolds carrying vascular endothelia growth factor has not been conducted.CONCLUSION: Development and application of PLA scaffolds carrying various sustained-release cytokines has become the new interest in bone tissue-engineering researches.
9.Analysis of coronary angiography characteristics in cases with acute myocardial infarction complicated combined with diabetes mellitus
Chinese Journal of Postgraduates of Medicine 2009;32(31):20-22
Objective To investigate the coronary angiography characteristics of acute myocardial infarction (AMI) combined with diabetes mellitus (DM). Methods Forty-five AMI patients combined with DM and 45 AMI patients without DM all received coronary angiography and the results were compared retrospectively, then the differences of coronary angiography and electrocardiogram characteristics were analyzed. Results The ratio of triple vessel lesions and diffuse lesions of coronary artery were more higher in AMI patients combined with DM than those in AMI patients without DM [64.4%(29/45) vs 35.6%( 16/45) and 82.2%(37/45)vs 40.0%(18/45),P< 0.05]. Non-ST segment elevation myocardial infarction (NSTEMI) was more common seen in AMI patients combined with DM than that in AMI patients without DM [37.8% (17/45)vs 17.8% (8/45),P<0.05]. Conclusion AMI patients combined with DM often have NSTEMI with triple vessel lesions and diffuse lesions of coronary artery.
10.Current microsurgery:its obstacles and development strategy
Chinese Journal of Orthopaedic Trauma 2002;0(03):-
Microsurgery has been in a plateau period after a development of 4 decades. Now it has been faced with a difficult situation in China: shrinking scope and increasingly slow development. This may be an inevitable outcome of the spiral rising pattern of development of anything in the world, as well as a combined result of fierce impact of market economy, hysteresis of medical system, ideological deviation and investment deficiency. Recently, however, application of new and high technology, new devices and materials in microsurgery, such as nanometer techniques and materials, gene and tissue engineering, and computerization, has broadened a new development space. Microsurgery in the 21st century should make more efforts in expanding its application dimension, perfecting its therapeutic methods, enhancing basic research, raising technical proficiency of its personnel and improving the welfare of its workers. It should also be nourished with new ideas, interdisciplinary cooperation before it can realize its rejuvenation in the new century.