1.Research progress on multiple mechanisms underlying visual hallucinations in schizophrenia patients
Yuchen JIANG ; Qiongyi HAN ; Xiaocui DU ; Guoting ZHEN ; Jindong TIAN ; Yao GAO ; Sha LIU ; Xinzhe DU
Chinese Journal of Nervous and Mental Diseases 2024;50(8):508-512
Visual hallucination(VH)is a common symptom of schizophrenia,the underlying mechanism has not been fully elucidated.It has been found that the dysfunction of dopamine(DA)system,the overactivation of α-amino-3-hydroxy-5-methyl-4-isoxazole-propionate(AMPA)receptor in glutamate system and the dysfunction of γ-aminobutyric acid(GABA)ergic neurons can induce VH in patients with schizophrenia.In addition,abnormalities in brain structural and functional networks and visual networks are also closely related to the occurrence of VH.The purpose of this paper is to review the neurochemistry and nerve injury mechanism of VH in schizophrenic patients to deeply understand the characteristics of VH,and make more accurate judgment in the early diagnosis,condition evaluation and treatment plan of schizophrenic patients.
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