Objective:To study the early predictive value of lung ultrasound score for bronchopulmonary dysplasia (BPD) in preterm infants with gestational age ≤32 w.Methods:From the establishment of the databases PubMed, Medline, Embase, Cumulative Index to Nursing and Allied Health (CINAHL), Cochrane Library, CNKI, CQVIP and Wanfang databases to February 17, 2022, studies on BPD with lung ultrasound score were searched. Literatures were screened according to the inclusion and exclusion criteria. The quality of the literature was evaluated and the eligible data were extracted. Stata 15.1 software was used for Meta-analysis.Results:Fourteen studies with a total of 1 645 preterm infants were included. The results showed that the sensitivity of the lung ultrasound score at 7 d of life predicting BPD was 0.71 (95% CI 0.64~0.77), the specificity was 0.83 (95% CI 0.74~0.89), and AUC was 0.81 (95% CI 0.78~0.84). At 14 d, the sensitivity was 0.64 (95% CI 0.59~0.69), the specificity was 0.89 (95% CI 0.72~0.96), and AUC was 0.68 (95% CI 0.64~0.72). Meta-analysis showed that sex, BA and birth weight were not sources of heterogeneity. Conclusions:Meta-analysis shows that lung ultrasound score has predictive value for BPD in preterm infants with GA ≤32 w, especially at 7 d of life. Lung ultrasound score is helpful in clinical decision-making.

Organ preservation fluid could mitigate cold ischemia injury and maintain normal function of the grafts. At present, how to reduce a series of injury caused by cold ischemia of donor liver and improve the preservation quality of grafts are the hot and challenging spots in this field. Currently, preservation fluid in clinical practice has not achieved ideal preservation effect, especially for the protection of marginal donor organs. In the context of severe donor shortage, the key solution is still to explore the optimal preservation protocol for donor liver to prevent grafts from cold ischemia injury. In this article, the mechanism of donor liver injury during cold ischemia, the classification and evolution of donor liver preservation fluid were summarized, the development direction and challenges of donor liver preservation fluid were discussed, aiming to provide novel ideas and references for the research and development of donor liver preservation fluid.