AIM:To analyze the effect of non-exchange transfusion therapy, including simple phototherapy or phototherapy combined with albumin therapy, on severe jaundice in full-term neonates.METHODS: The full-term neo-nates (n=110) with serum total bilirubin (TBIL) level over 342 μmol/L recewed simple phototherapy or phototherapy combined with albumin therapy.The changes of serum bilirubin levels and neurological signs of these neonates were ob-served.RESULTS:Serum TBIL and indirect bilirubin ( IBIL) levels in the 2 groups of hospitalized cases significantly re-duced after the first day of treatment and at discharged (P<0.01).The reduced degrees of TBIL and IBIL levels in the neonates given phototherapy combined with albumin therapy were higher than those in the neonates given simple photothera-py.All these neonates did not have bilirubin encephalopathy on admission or at discharged.CONCLUSION:Both simple phototherapy and phototherapy combined with albumin therapy treat severe jaundice effectively and prevent acute bilirubin encephalopathy in full-term neonates.

0.05). Conclusions These results suggest that NKX3.1 is prostate-specific homeobox gene,and it may play an important role in the development of prostatic carcinoma.It is shown that analysis of the expression of NKX3.1 in prostatic carcinoma will benefit the diagnosis and treatment of prostatic carcinoma.

OBJECTIVE To investigate the resistance of Pseudomonas aeruginosa strains to 5 ?-lactams.METHODS Susceptibility of 218 P.aeruginosa strains isolated from Anhui Province in 2005 to ceftriaxone,cefotaxime,ceftazidime,aztreonam,and piperacillin were tested by agar dilution method.RESULTS The resistance rate to ceftriaxone,cefotaxime,aztreonam,piperacillin,and ceftazidime were 59.2%,57.3%, 56.0%,51.8%,and 39.0%,respectively.There was statistically significant difference between ceftazidime and other 4 ?-lactams(P0.05).CONCLUSIONS Ceftazidime is the most susceptible antibiotic to P.aeruginosa strains among 5 ?-lactams tested.

Objective To develop a method for simultaneous determination of three kinds of anti-dandruff agents,namely ketoconazole,climbazole,piroctone olamine,in cosmetics by HPLC.Methods The cosmetics were extracted with acetonitrile by ultrasonic,then separated with high-speed centrifuge.The supernatant layer was filtrated through membrane with 0.45 ?m diameter.The filtration liquid was injected into HPLC for detection at ?=210 nm.Quantitative analysis was performed with external standard method.Results In the linear range of 1-250 mg/L,the regression equation of ketoconazole was y=32.23x+ 4.59,the detection limit was 0.069 mg/L.In the linear range of 1-500 mg/L,the regression equation of climbazole was y=13.76x+ 9.41,the detection limit was 0.12 mg/L.In the linear range of 10-500 mg/L,the regression equation of piroctone olamine was y= 24.83x-17.17,the detection limit was 0.71 mg/L.The recoveries and relative standard deviations were 91.8%-98.5% and 0.38%0.84%,respectively.Conclusion The experimental results show that the method is simple,precise and accurate and suitable for simultaneous determination of 3 kinds of anti-dandruff agents in cosmetics.

With the development and the expansion of higher medical education,lack of course resource became a “bottleneck” which restricted the development of medical schools.Teaching hospitals played some roles in medical education,but there was a huge gap in teaching ability between these hospitals and the hospitals affiliated with universities.The Clinical College analyzed the current situation of teaching ability in teaching hospitals and did the preliminary research for the solutions of this situation.

Our hospital has set up a relatively complete assessment methods after nearly 10 years of residents/medical specialist training, including the day-to-day assessment, periodic assessment,comprehensive assessment,and completed the corresponding management evaluation.

Residents(medical specialists)programmed education is an important aspect to fulfill the post-graduated medical education. It can remedy the clinical practice of young doctors,which ac-cords with the trend of international medical education .This article is to give advice for the resi-dents (medical specialists)programmed education according to the work and existing problems in our hospital.

Setting up medical specialists education system is the requirement of the re-form and development of medical sciences and health causes and is a must to train medical specialists. It is of significance to perfect medical education and standardize residency training and management in China,so as to promote medical education and talents management to be in line with the world.

We have established the model of English ability training on the residency training project,and have provided the systematic training plan to 29 residents who were employed in 2005.This paper summarizes the effect and points out the further reform perspectives.

AIM: To observe the effect and mechanism of Chinese traditional medicine JianNao mixture on function of learning and memory in memory disorder mice. METHODS: Step down test, step through test and "Y" maze test were used to examine the function of learning and memory in memory disorder mice induced by scopolamine, sodium nitrite and alcohol, and in dementia model mice induced by D galactose and aluminum chloride. Cholinesterase activity in brain, LPO and SOD in blood were measured. RESULTS: JianNao mixture could promote both the learning and memory function in impaired acquisition, consolidation and retrieval of memory in memory disorder mice induced by scopolamine, sodium nitrite and alcohol, respectively. It also could reduce wrong times and prolong latency in mice's step through test, depress cholinesterase activity of brain in aluminum chloride model mice, reduce wrong times in mice's "Y" maze test, enhance SOD activity of whole blood and decrease LPO content of brain in D galactose model mice. CONCLUSION: JianNao mixture can improve the function of learning and memory in memory disorder mice. The mechanism may be due to improve the cholinergic function and the balance of free radical in vivo.