1.Diagnostic Value of Dual-phase Enhanced Scan in Detecting Pancreatic Adenocarcinoma with Dual Energy CT
Weiqun AO ; Guoqun MAO ; Guangzhao YANG ; Hongxia ZHANG ; Hongtao HOU
Chinese Journal of Medical Imaging 2016;24(12):909-912
Purpose To explore the diagnostic value of multiple image technique derived from dual-energy CT in arterial+parenchymal phase scan mode in detecting pancreatic adenocarcinoma so as to provide more valuable information for clinical treatment.Materials and Methods Thirty two patients with pancreatic adenocarcinoma proved pathologically underwent dual-phase scan with dual-source CT.Linear blend image,non-linear blend image and iodine map were acquired.The absolute enhancement value of tumor (AEV),the relative enhancement value of tumor (REV),enhancement ratio (ER) of tumor to pancreatic parenchyma,and the image contrast to noise ratio (CNR) were also calculated,so that the diagnostic value and the ability image in two phases to display the pancreatic adenocarcinoma lesions could be assessed.Results On arterial phase,the differences in AEV,REV and CNR value were significant among the three groups images (P<0.05).On parenchymal phase,the difference in REV,ER,and CNR value were also significant among the three groups (P<0.05).When the three sequences on the 2 phases were compared with each other,the differences in AEV and REV value of tumor tissues were significant among the groups (P<0.05).Moreover,the differences of ER value in linear blend image and CNR in the iodine map were significant in dual phase enhancement (P<0.05).Conclusion Dualenergy CT enhanced scan mode on dual phase combined with multiple sequences can improve the sensitivity in detection of pancreatic adenocarcinoma lesions.
2.Randomly comparative study on the therapeutic effects of Fufangkushen injection and Aidi injection on improving quality of life for patients with advanced lung cancer
Xuemin ZHANG ; Jie CHEN ; Xiaodong GUO ; Weiwei ZHANG ; Guoqun XIE ; Keqi HAN
Cancer Research and Clinic 2012;24(3):153-156
Objective To explore and compare the therapeutic effects of Fufangkushen injection and Aidi injection on improving quality of life for patients with advanced lung cancer. Methods 60 patients in late stage of lung cancer with pathological diagnosis were split into two groups randomly. 30 patients in Kushen group received Fufangkushen injection plus base therapy, 30 patients in Aidi group received Aidi injection plus base therapy.The data was analyzed on term of tumour size,clinical symptoms,Karnofsky score,cancer marker CA125,CEA,before and after treatment in two groups.The therapeutic effects were evaluated after two circles of treatment. Results Compared the short term therapeutic effect, Kushen group had the stability rate for 83.3 %(25/30),and 80.0 %(24/30) for Aidi group.There was no significant difference.(P>0.05).Compare the clinical therapeutic effect,Kushen group had the improving rate for 83.3 %(25/30),and 80.0 %(24/30) for Aidi group.There was no significant difference(P>0.05).Compare the Karnofsky score,two groups had equal increasing stability rate (P>0.05). Compare decreasing ratio of CEA and CA125 after treatment in two groups,there was no significant difference (P>0.05). Conclusion Fufangkushen injection and Aidi injection both have acceptable therapeutic effects in the treatment of patients with later stage lung cancer.The result is equal. As well as they have some other characters themselves to improve lung cancer related symptoms. Fufangkushen injection is better to improve symptoms of heat toxin, and Aidi injection is better to improve symtoms of deficiency Qi. For Fufangkushen injection, it can also adjust disorder of liver function and relieve pain.
3.Application of multi-slice spiral CT in the screening of coronary artery lesions in elderly patients with diabetes mellitus
Xiaoliang CHEN ; Xinliang CHEN ; Suqin ZHANG ; Guoqun MAO ; Mingfang LOU ; Huaguan ZHANG ; Yao CHEN ; Caigan ZHANG ; Wenyu WANG ; Linsheng WU ; Juan LI ; Min JIN ; Hongyan WANG
Chinese Journal of Geriatrics 2017;36(9):963-965
Objective To evaluate the clinical value of multi-slice spiral CT (MSCT)in the screening of coronary artery lesions in elderly patients with diabetes mellitus.Methods MSCT and coronary angiography(CAG)were performed in 136 elderly patients(68 patients with diabetes and 68 patients without diabetes).The number of diseased coronary segments and the plaque type (noncalcified,mixed and calcified)for each patient were determined.The characteristics of coronary lesions were compared between patients with and without diabetes.The sensitivity and specificity of MSCT were evaluated.Results More noncalcified and calcified plaques and few ermixed plaques were observed in patients with diabetes,compared with patients without diabetes(noncalcified plagues:10 cases or 14.7% vs.4 cases or 5.9%;calcified plagues:47 cases or 69.1% vs.39 cases or 57.4%)(P< 0.05).In addition,diabetic patients showed a significantly higher frequency of multivessel disease(P<0.05).Furthermore,MSCT was able to clearly show stenosis and plaque type in the trunk and branches of the coronary artery,with a sensitivity of 91.0%,a specificity of 95.0%,a positive predictive value of 93% and a negative predictive value of 96.0%.Conclusions Diabetes is associated with a higher risk of coronary artery disease.MSCT can effectively detect the characteristics of coronary artery disease in diabetic patients and is an effective,noninvasive,and safe screening method.
4.Appraisal preventive effects of meridian stretch stocking on postgynecological pelvic surgery to LEDVT
Huiling ZHOU ; Xiuhua CHENG ; Yanling GAN ; Meng HU ; Guoqun ZHANG
Chinese Journal of Modern Nursing 2016;22(1):80-84
Objective To explore the effects and influences of meridian stretch stocking for prevention of lower extremity deep vein thrombosis ( LEDVT ) after gynecological pelvic surgery. Methods A total of 210 patients,who conducted pelvic surgery at Department of Obstetrics and Gynecology, Wuhan Third Hospital from April 2010 to February 2013, were randomly divided into routine group (Group A), the common stretch stocking group ( Group B) and meridian stretch stocking group ( Group C) , 70 cases in each group,according to their check-in time. The patients of Group A followed routine nursing methods, and the patients of Group B complied with normal stretch stocking while the patients of Group C adopted meridian stretch stocking. The usage of stretch stockings was on the basis of conventional nursing methods and applied immediately after the surgery. Then a series of comparisons were made in terms of lower extremity venous blood flow velocity, foot dorsum skin temperature and the incidence of LEDVT, coagulation and fibrinolytic function, etc. Results Group C possessed the lowest LEDVT incidence in three groups and the differences were statistically significant (χ2 =6. 667,P<0. 05). Meanwhile Group C had the fastest posterior divisions superficial vein and popliteal fossa vein blood flow velocity with statistical significance compared with the other two groups (P<0. 01). The lower limb dorsal skin temperature of Group C was higher than that of Group A and Group B after two and four hours′ surgery ( P<0. 01). There was no statistical difference in blood coagulation and fibrinolytic function of the three groups (P>0. 05). Conclusions Meridian stretch stocking can advance venous blood flow velocity, improve lower limb dorsal skin temperature and reduce LEDVT incidence of patients with gynecological pelvic surgery.