1.Application of digital artery island flap for soft tissue defects of finger
Chinese Journal of Minimally Invasive Surgery 2001;0(03):-
Objective To investigate the effectiveness of repair of soft tissue defects of finger by using the digital artery island flap.Methods A total of 25 cases of soft tissue defects of finger were treated by using the digital artery island flap in this department from August 2003 to November 2004.The flap was 2.0~3.0 cm ? 1.5~3.0 cm in size.Results The flap had survived in all the 25 cases.The operation time was 60~90 min(mean,75 min),and the intraoperative blood loss was 25~40 ml(mean,32 ml).The skin graft necrosed by one-third of area in 2 cases,which was cured by a re-grafting.Follow-up observations in 23 cases for 6~18 months(mean,13.5 months) revealed the flaps with normal color,elasticity,and appearance.The static two-point discrimination was 6.5~8.8 mm(mean,7.5 mm).The digital pain and temperature sensation had recovered to normal,and the patients reported satisfactory sensory and motor functions.Conclusions Characterized by simple performance and satisfactory outcomes,digital artery island flap is an ideal choice for the coverage of soft tissue defects of finger.
2.Application of APACHE Ⅱ scoring system in severe cerebral hemorrhage
Clinical Medicine of China 2011;27(11):1167-1169
Objective To evaluatethe application value of APACHE Ⅱ on the prognoses in prediction of pin hole multi-directional intracranial hematoma aspiration to cure severe cerebral hemorrhage.Methods APACHE Ⅱ scoring system was conducted in randomly collected 58 severe cerebral hemorrhage patients' data (30 patients underwent surgical treatment,28 patients underwent conservative treatment)to evaluate the disease severity,prognosis and effect of the pin hole multi-directional intracranial hematoma aspiration.Results The APACHE Ⅱ score of treatment group on the first day was 28.00 ± 1.92 and the predicted mortality was 0.86 ±0.03.The score was decreased obviously on the tenth day(8.20 ± 0.76)and the predicted mortality was 0.57 ± 0.05.The actual mortality was 33.33%.Conclusion APACHE Ⅱ scoring system is suitable for judging the disease severity and predicting the prognosis of severe cerebral hemorrhage patients,it proves that surgical treatment effect of the pin hole multi-directional intracranial hematoma aspiration is remarkable.
3.Inhibition of Bcl-2 Antisense Oligonucleotide Combined with Radiation against Lung Carcinoma Cells
Wei HU ; Guoping SHAN ; Changhui YU
Journal of Zhejiang Chinese Medical University 2007;0(01):-
[Objective] To study the inhibitory effect of bcl-2 antisense oligonucleotide(ASODN)combined with radiation on lung carcinoma cells NCI-H446.[Method]The cultured NCI-H446 lung carcinoma cells were divided into 5 groups:control,pure radiation,nonsense+radiation,lipofectin+radiation,ASODN+radiation.Every group except for control were assayed by MTT on the inhibition rates,24h,48h,72h after 10Gy irradiation respectively.[Results]The inhibitions of lung carcinoma cells NCI-H446 were observed in ASODN+radiation,lipofectin+radiation,nonsense+radiation and pure radiation groups.The differences between the ASODN+radiation group and the other three groups were significant(P
4.Balloon catheter dilation of benign esophageal stenosis in children.
Guoping FAN ; Juming YU ; Weixing ZHONG
Journal of Interventional Radiology 1994;0(03):-
Objective To evaluate the methods and effect of balloon catheter dilation of benign esophageal stenosis in children. Methods 9 cases had an anastomotic stenosis after surgical correction of esophageal atresia; 11 cases of esophageal stenosis due to ingestion of caustics; one case had an lower esophageal stenosis after Nissen surgery and one case after gastroesophagoplasty. Age ranged from 17 days to 7 years. Each case had a barium esophagram before balloon dilation. The balloon size varied from 3 to 10 mm in diameter. Results 21 cases were successful after dilation of balloon catheter. There were no esophageal perforation and complications. The satisfactory results maintained from six months to thirty months. Conclusions Balloon catheter dilation is a simple、safe and reliable method for the treatment of benign esophageal strictures in children as the first choice.
5.Balloon catheter dilation of esophageal caustic ingestion stenosis in children
Juming YU ; Guoping FAN ; Weixin ZHONG
Journal of Interventional Radiology 2001;0(05):-
Objective To evaluate the methods and effect of balloon catheter dilation of esophageal caustic ingestion stenosis in children. Methods We analysed 18 cases, including 10 cases of esophageal stenosis due to ingestion of sulphuric acid, 7 cases of esophageal stenosis caused by ingestion of sodium carbonate and the last one through ingestion of chemical materials include zinc sulphate. Barium esophagogram was taken before dilation for every patient and the balloon size varied from 4 mm?40 mm to 16 mm?40 mm or 20 mm?40 mm in diameter was selected for the procedure. Results 18 cases were all successful in dilation by balloon catheter, without esophageal perforation and other complications. The satisfactory results maintained from six months to thirty months with remarkable improvement clinicoly. Conclusions Balloon catheter dilation is a simple, safe and reliable method for the treatment of esophageal caustic ingestion stenosis in children, and should be recommended as the first choice.
6.Research on information support services of hospital research projects
Lili WANG ; Guoping YU ; Peiguo XU
Chinese Journal of Medical Science Research Management 2011;24(2):131-132
This paper analyzes the needs for and feasibilities of information support services at hospital libraries for scientific research.It also explores the major contents of hospital information support services,hoping to find a more reasonable information services model to meet the needs of the rapidlygrowing research projects.
7.Determination of Dracorhodin and Curcumin in Dieda Pills by UPLC
Chunhui ZHANG ; Yu YU ; Guoping WANG ; Chao FU ; Youlan WANG
China Pharmacist 2016;19(6):1206-1208
Objective:To determine the content of dracorhodin and curcumin in Dieda pills by UPLC .Methods:A UPLC method was adopted.The determination was performed on a Waters Acquity UPLC BEH C 18 column(100 mm ×2.1 mm,1.7 μm) with the mobile phase consisting of acetonitrile-0.05 mol· L-1 NaH2PO4(50 ∶50).The detection wavelength was 440 nm for dracorhodin and 431 nm for curcumin, the column temperature was 30℃and the flow rate was 0.1 ml· min-1 .Results:There was a good linear range of 0.001 8-0.036 4 μg(r=0.999 9)for dracorhodin and 0.000 8-0.015 6 μg(r=0.999 9) for curcumin.The average recovery for dracorhodin was 97.94%(RSD=0.89%) and that for curcumin was 98.45%(RSD=0.91%).Conclusion:The method is simple, rapid and reproducible ,which can be used for the determination of dracorhodin and curcumin in Dieda pills .
8.Interventional treatment of intracranial arteriovenous fistula in infants
Juming YU ; Guoping FAN ; Weixing ZHONG ; Ming ZHU
Journal of Interventional Radiology 2006;0(08):-
Objective To evaluate the efficacy and safety of embolization therapy with NBCA for intracranial arteriovenous fistula (AVF) in infants. Methods Four patients with cerebral arteriovenous fistula were reported, including 3 males and 1 female with nonspecific symptoms and signs, and the diagnosis was made by DSA. Three of them were treated by embolization therapy with NBCA. Results Three of the cases were treated by NBCA, neither death nor complication occurred. Conclusion Intracranial AVF is rare in childhood. Endovascular treatment with NBCA is effective and safe, but the long-term effect has to be comfirmed by follow-up study. (J Intervent Radiol, 2006, 15: 451-452)
9.Interventional therapy for post-anastomotic stenosis in congenital esophageal atresia
Juming YU ; Guoping FAN ; Weixing ZHONG ; Ming ZHU
Journal of Interventional Radiology 1994;0(04):-
Objective To report the results of balloon catheter dilation in 13 infants with anastomotic stenosis after surgical correction of esophageal atresia. Methods Thirteen cases of anastomotic stenosis after surgical correction of esophageal atresia were enrolled, age ranging from 3 to 10 years. Barium esophagography before balloon dilation showed the diameter of esophageal stenosis ranging 1 to 3 mm and the stenosis was dilated by using balloons of 6 to 12 mm diameter. Results All the 13 cases obtained complete resolution of the stenosis after dilation for twice or thrice. There was no esophageal perforation or other complications with a period of clinical symptomless of 6 to 30 months. Conclusions Ballon catheter dilation is a simple, safe and reliable method for treating anastomotic esophageal stenosis in infants.
10.Clinical evaluation of urinary interventional therapy in children
Guoping FAN ; Juming YU ; Weixing ZHONG ; Ming ZHU
Journal of Interventional Radiology 1994;0(04):-
Objective To evaluate the role of interventional therapy in Wilm's tumor, renal vascular lesions and ureter stricture in children. Methods Thirty-eight cases were analysed, including 18 cases of Wilm's tumor treated with preprocedural chemotherapy and embolization through renal artery, and 13 cases of unknown-reason hypertension with selective renal arterial angiography for venous blood renin including undergone some patients PTA. Six cases of ureter stricture were dilated with balloon and 1 with hematurea by small aerial embolization. Results After embolization, Wilm's tumors showed reduction in vascularization and reduction in size too. The surrounding tissue of the tumor had a clear demarcation with the normal tissue, decreasing the dissemination to blood and distal metastasis. Renal vascular hypertension was clearly diagnosed and treated, and the increase of renin was helpful to the diagnosis of unknown-reason hypertension. And the obstruction of ureter was improved. Conclusions Interventional therapy is feasible in the application of urinary system diseases with great significance clinically.