1.Construction of Teacher's Professional Morality in Medical Colleges in the Perspective of a Harmonious Society
Chinese Medical Ethics 1995;0(04):-
Construction of teacher's professional morality is a major issue that matters the development of both teachers themselves and medical colleges,especially under the current circumstances of constructing a harmonious society.This article summarizes the phenomenon of absence in teacher's professional morality in market-oriented economy,elaborates theoretically the necessity of strengthening teacher's professional morality construction in medical colleges,and proposes briefly strategies to strengthen the construction of teacher's professional morality.
3.Method and Technic for Cluster Electrode Radiofrequency Hyperthermia Ablation of Liver Cancer by CT Guiding
Lijun SONG ; Guomin LIANG ; Ji ZHANG
Chinese Medical Equipment Journal 2003;0(10):-
Objective To evaluate the applied value of CT guiding the liver cancer ablation with cluster electrode radiofrequency hyperthermia. Methods 105 cases with local lung cancer were ablated with cluster electrode radiofrequency hyperthermia by whole body CT-ELSCINT 2400ELECT. Results Success rate of 105 cases CT guiding was 98.3% and the total remission rate was 82.8%. Conclusion It is with CT that the location of percutaneous puncture can be optimally selected, and the point view and depth of the electrode can been detected anytime; also, the internal local focus can be monitored. So, the CT guiding is the optimal method to guide cluster electrode radiofrequency hyperthermia ablation for lung cancer.
4.Evaluation of Equilibrated Reconstruction on DR Abdominal-imaging
Lijun SONG ; Guomin LIANG ; Ji ZHANG
Chinese Medical Equipment Journal 2003;0(10):-
Objective To study the difference between images of DR with or without equilibrated reconstruction. Methods 200 samples undergoing DR abdominal imaging from April 2003 are chosen orderly. Results All details of different tissue can be displayed in an image by adopting Equilibrated Reconstruction, while standard DR images should adjust the width and position of the window to get the same effect. Conclusion Equilibrated Reconstruction technology could improve image quality of different tissues without loss of details of other parts, and make DR more consummate and operation more convenient. It raise the ratio of displaying lesions.
5.Study on the short version of work attitude scale and its reliability and validity
Guomin CHEN ; Lijun WANG ; Suping MENG ; Kewen SONG ; Hongmei LI
Chinese Journal of Behavioral Medicine and Brain Science 2011;20(10):948-951
Objective To conduct item analysis on Work Attitude Scale(Wa) and to develop a short-versioned scale.Methods Wa and Symptom Checklist 90(SCL-90) were administered to 3767 recruits,item analysis of Wa was conducted and short version of Wa was developed based on the results of item analysis,Cronbach' s αcoefficient of the original scale and the short-versioned scale was calculated,criterion validity of the original scale and the short-versioned scale was analyzed using SCL-90 as the validity criterion.For other samples,16 Personality Factor Questionnaire (16PF),Eysenck Personality Questionnaire ( EPQ),and Self-Rating Anxiety Scale (SAS) were tested while the short-versioned scale was tested at the same time,criterion validity of the short-versioned Wa was analyzed using 16PF,EPQ,and SAS as the validity criterion.Results Difficulty of the original scale was from 0.03 to 0.87,27 items' difficulty was less than 0.20 or greater than.Discrimination index was from 0.04 to 0.56,22 items' discrimination index was less than 0.30.Correlation coefficient of the item score and the total score is from 0.02 to 0.52,18 items' correlation coefficient was less than 0.30.The short-versioned scale was made up of the 18 items with better quality.Cronbach' s α coefficient of the original scale and the short-versioned scale was 0.778 and 0.789,respectively.Both the total score of the original scale and the short-versioned scale were significantly correlated with the scores of SCL-90,and all the correlation coefficient were above 0.40.The correlation coefficient between the score of the short-versioned scale and that of the original scale was 0.934.The correlation coefficient between the score of the short-versioned scale and 16PF,EPQ,SAS was significant.Conclusion The short-versioned scale has a higher reliability and good validity.
6.Research in literatures about the deep vein thrombosis after hip replacement at home and abroad
Junxiao LIAN ; Yan WANG ; Guomin SONG ; Yuan ZHAO
Chinese Journal of Practical Nursing 2014;30(15):74-76
Objective To explore clinical progress about the deep vein thrombosis after hip replacement at home and abroad,and discuss the preventive effect of nursing intervention.Methods The documents about the deep vein thrombosis after hip replacement were retrieved from PUBMED,China National Network Knowledge Infrastructure (CNKI),Chinese Scientific Journal Database (VIP),Chinese Bio Medical Literature Database (CBM) and Wan fang Database.And the retrieving duration was from 1st Jan.2001 to 1st Sept.2013.The research progress about prevention of deep vein thrombosis after hip replacement was analyzed through the analysis of the same and the difference of comparative literatures at home and abroad.Results There were totally 228 Chinese documents and 5 English documents of the deep vein thrombosis after hip replacement,and the number of document showed an increasing trend year by year.In the past five years,the clinical progress about the deep vein thrombosis after hip replacement was obvious,the research methods used was accurate,the involving intervention measures was continuously improved,literature quality was increased.Conclusions The quality of the documents published in domestic Chinese journals needs to be improved,and we should improve the quality of research design,research new methods of intervention,formulate the optimal nursing measures in order to achieve optimal care.
8.The expressions of aquaporins in chronic stress depression model rat hippocampus and gastrointestinal mucosa
Weixi SONG ; Tingting CHEN ; Guang ZENG ; Yanping TANG ; Beiyang CHEN ; Guomin ZHANG
Chinese Journal of Behavioral Medicine and Brain Science 2013;22(9):794-796
Objective To study the mechanisms of depression by exploring expressional differences of AQPs in the tissues of chronic stress depression rats.Methods Depression model was replicated by unpredicted chronic stress.20 rats were randomly separated into normal control group and model control group,AQP4 and AQP3,AQP8 expressions on hippocampus and gastrointestinal mucosa of rat model with depression were detected by immunochemical staining method.Results Means of optical density of AQP4 of normal group and model group hippocampus were 0.28 ± 0.02,0.22 ± 0.06 respectively,and the difference between two groups was significant statistically(t value was 2.756,P<0.05).The expression of AQP3 on gastric mucosa and colonic mucosa between two groups had no significant statistically(t value were 1.814,1.812,P>0.05).Two groups'means of optical density of AQP3 on small intestinal mucosa were 0.15 ± 0.02,0.17 ± 0.02,and the difference was significant statistically (t value was 2.769,P<0.05).Two groups'means of AQP8 optical density in gastric mucosa were 0.15± 0.01,0.19 ± 0.04 ;0.16 ± 0.01 and 0.21 ± 0.04 in small intestinal mucosa;0.16 ± 0.01 and 0.22 ± 0.04 in colonic mucosa,and the differences were significant statistically(t values were 3.139,5.113,4.534,P<0.05,P<0.01,P<0.01).Conclusion The expression of AQP4 on depression model rat hippocampus are lower than those of the normal group ; and the expression of AQP3 on gastric mucosa and colonic mucosa are no change obviously,but it(')s up-regulation on small intestinal mucosa.The expressions of AQP8 on gastric mucosa and small intestinal mucosa and colonic mucosa are up-regulating.
9.Effects of Bushen Huoxue Prescription on Granulosa Cell Apoptosisi of Premature Ovarian Failure Mice
Huiping LIU ; Yi XIAO ; Ling LI ; Peng QI ; Yan SONG ; Jiajun LI ; Haiqing YI ; Chao KE ; Guomin ZHANG
Chinese Journal of Information on Traditional Chinese Medicine 2015;(4):47-50
Objective To discuss Bushen Huoxue Prescription mechanism of action on follicular granulosa cell apoptosis of premature ovarian failure (POF) mice. Methods The mouse zona pellucida 3 as the antigen, multi-point injection of subcutaneous immunization BALB/c to female mice was used to establish autoimmune POF model. Forty clean female mice were randomly divided into blank group, model group, Estradiol Valerate group and Bushen Huoxue Prescription group. All medicine groups were given relevant medicine for gavage, while model and blank groups were given normal saline with the same amount for gavage for 15 days. After the treatment, ovary, uterus, and thymus were weighed, and the viscera index was calculated. An ovarian slice was taken and HE staining was used to observe granulosa cell apoptosis. The levels of E2, LH, and FSH were detected by using the radioimmunoassay method. RT-PCR was used to analyze Fas and Fas-L mRNA expressions in ovarian granulosa cells. Results Compared with blank group, the weight of ovary, thymus, and uterus decreased significantly (P<0.05, P<0.01);Serum E2 level dropped (P<0.01);levels of FSH and LH, and expressions of Fas and Fas-L mRNA increased significantly (P<0.01). Compared with model group, granulosa cell apoptosis significantly decreased, and ovary index, uterus index, and thymus index increased (P<0.05);serum E2 level increased (P<0.01);levels of FSH and LH, and expressions of Fas and Fas-L mRNA significantly decreased (P<0.05). Conclusion Bushen Huoxue Prescription can decrease expressions of Fas and Fas-L mRNA to inhibit cell apoptosis by adjusting the hormone level of hypothalamus-pituitary-ovarianaxis.
10.Correlation between serum miR-122-5p and FOXO3 levels and osteoporosis in postmenopausal women with non-alcoholic fatty liver disease
Fangjie ZHANG ; Song WANG ; Guomin ZHANG ; Ruijuan ZHAO ; Yaomin LIU
Chinese Journal of Endocrine Surgery 2023;17(6):748-752
Objective:To investigate the correlation between serum miR-122-5p and FOXO3 levels and osteoporosis (OP) in postmenopausal women with non-alcoholic fatty liver disease (NAFLD) .Methods:The clinical data and serum of 30 postmenopausal women with NAFLD and 48 postmenopausal women with no-NAFLD were collected. The levels of miR-122-5p and FOXO3 in serum were detected by qRT-PCR. Triglycerides, high-density lipoproteins, and low-density lipoproteins were detected by biochemical autoanalyzer. The bone mineral density of lumbar vertebrae 1-4, Wards triangular bone, femoral neck, greater trochanter and total hip was detected by bone mineral density analyzer. The correlation between the above clinical indicators and OP was analyzed.Results:The expression of miR-122-5p in postmenopausal female NAFLD patients (0.76±0.28) was lower than that in non-NAFLD patients (1±0.31) ( t=3.43, P=0.001) . The downstream target gene FOXO3 of miR-122-5p was identified by bioinformatics website analysis. The expression of FOXO3 in postmenopausal female NAFLD patients (1.31±0.30) was higher than that in non-NAFLD patients (1±0.27) ( t=4.73, P<0.001) . Student’ s t test and Logistic regression analysis showed that triglyceride, miR-122-5p and FOXO3 levels were risk factors for NAFLD (all P<0.05) . Pearson correlation coefficient showed that miR-122-5p level was significantly positively correlated with BMD of femoral neck ( r=0.488, P=0.006) , greater trochanter ( r=0.367, P=0.046) and whole hip ( r=0.404, P=0.027) . FOXO3 level was negatively correlated with bone mineral density of femoral neck ( r=-0.445, P=0.014) and whole hip ( r=-0.507, P=0.004) , while other indexes were not significantly correlated (all P>0.05) . Conclusion:Decreased serum miR-122-5p level and increased FOXO3 level in postmenopausal women with NAFLD may increase the risk of OP.