1.Research progress of isolated superior mesenteric artery dissection
Chinese Journal of Digestive Surgery 2015;14(9):773-776
Isolated superior mesenteric artery dissection (ISMAD) is a clinically common disease,of which multi-slice spiral computed tomography (MSCT) is effective method for screening and follow-up.The diagnosis and treatment should be made based on pathological changes of true or and false lumen.Most patients can relieve by medical treatment,and those with treatment failure can adapt endovascular treatment.Patients with aneurysm rupture or intestinal necrosis should undergo emergent surgical treatment.
2.Tumor lysis syndrome following transarterial chemoembolization for advanced hepatocellular carcinoma:report of one case
Zhongzhi JIA ; Feng TIAN ; Guomin JIANG
Journal of Interventional Radiology 2014;(9):835-837
Tumor lysis syndrome (TLS) results from a sudden and rapid release of nuclear and cytoplasmic degradation products from malignant cells. It is a rare complication in adult patients with solid tumors who are undergoing treatment. Herein, the authors present a case with advanced hepatocellular carcinoma (HCC) who developed TLS after transarterial chemoembolization (TACE), which was successfully treated with aggressive fluid administration, oral allopurinol and urine alkalization, hemodialysis and other supportive therapies. TLS following TACE should be suspected in HCC patients who has large and rapidly-growing lesion.
3.Design of Portable Medical Measure System on Palm
Shumin JIANG ; Guomin MO ; Yan WANG
Chinese Journal of Medical Physics 2010;27(2):1773-1776
Objective: This item presents a feasible scheme of home monitoring device which is a low power and miniaturization equipment for human signal detection, based on single-chip technology. Methods: Taking MSP430F149 as core, the realized functions of system contain real time data acquisition, data processing, data storage, LCD and alarming, keyboard as well as com-munication, replay and reproeessing by host computer. Results: The physiological and biochemical parameters are acquired by system and transmitted to host computer. Conclusions: This design provides a platform for multi-parameters portable detection just as dynamic ecg, ambulatory blood pressure, and so on. It has a good future for application.
4.Effects of mild hypothermia on neuron specific enolase following brain injury in rats
Guomin XIAO ; Weimin WANG ; Qizhou JIANG
Chinese Journal of Trauma 2003;0(09):-
Objective To observe the effects of mild hypothermia on the dynamic change of neuron specific enolase (NES) in serum, the damaged neuron number around the impact site and the content of brain tissue water following traumatic brain injury (TBI) in rats so as to provide a quantitative parameters to evaluate the protective effect of the mild hypothermia on the brain. Methods A total of 45 SD rats were subjected to a lateral moderate cortical impact injury caused by a free-falling object and divided randomly into three groups:⑴ sham operation group (Group A);⑵ normothermic group (Group B);⑶ hypothermia group (Group C). The Group C was treated with mild hypothermia and the Group B with normothermia immediately after injury. A series of samples were obtained directly 3, 6 and 24 respectively after trauma in three groups. Pathomorphological method was used to observe the number of the damaged cortical neurons around the impact site. The serum concentration of NSE and the water content of brain tissue water were measured by radio-immunoassay. Results Following TBI in rats, the serum level of NSE was significantly increased (P
5.Transcatheter arterial embolization for the treatment of advanced bladder cancer:clinical analysis of ;22 cases
Yulin WANG ; Rongkui HU ; Zhongzhi JIA ; Feng TIAN ; Guomin JIANG
Journal of Interventional Radiology 2015;(4):311-313
Objective To investigate the therapeutic efficacy of transcatheter arterial embolization (TAE) in treating advanced bladder cancer. Methods A total of 22 patients with advanced bladder cancer were included in this study. The clinical data and the imaging materials were retrospectively analyzed. The clinical efficacy of TAE in treating advanced bladder cancer was evaluated. Results TAE was successfully accomplished in all the 22 patients. The preoperative and the postoperative abdominal pain scores were 4.73± 1.91 and 2.45±1.29 respectively, the difference was statistically significant (P<0.01); the preoperative and the postoperative ECOG scores were 3.14±0.47 and 2.68±0.56 respectively (P<0.05); the preoperative and the postoperative hemoglobin levels were (61.4±11.8) g/L and (79.3±14.5) g/L respectively (P<0.01). Of 7 patients with urinary tract obstruction, after the treatment the obstruction disappeared in 5 and was improved in 2, although the urination was still not smooth. All patients were followed up for (7.1±3.0) months. The 6-month survival rate was 54.5% (12/22). No serious complications occurred in all patients. Conclusion TAE can not only effectively improve the hematuria and urinary tract obstruction symptoms caused by bladder cancer, but also effectively control the tumor growth, improve the quality of life and prolong the survival time as well.
6.Successful placement of nutrition tube via transhepatic route for duodenal obstruction due to pancreatic cancer:report of one case
Zhongzhi JIA ; Feng TIAN ; Kai WANG ; Guomin JIANG
Journal of Interventional Radiology 2015;(6):553-555
Usually the survival period of patients with duodenal obstruction caused by inoperable advanced pancreatic cancer is rather short. For such patients, minimally invasive treatment should be employed as the first choice. This paper reported a case with advanced pancreatic cancer complicated by biliary and duodenal obstruction. After implantation of biliary stent, the obstructive jaundice was relieved. Because of the insufficient cardiac function, the patient was not able to tolerate gastrojejuostomy; besides, as both DSA-guided stent implantation and endoscopic nutrition tube placement failed to success, implantation of nutrition tube via the trans-hepatic and biliary route, as a novel tube placement technique, had to be carried out, and the result in this case was satisfactory.
8.The efficacy of different embolic agents to block bronchial artery for massive hemoptysis secondary to bronchiectasis or pulmonary tuberculosis
Xin YUAN ; Feng TIAN ; Jun ZHOU ; Guomin JIANG ; Xiaowei YU
The Journal of Practical Medicine 2017;33(9):1464-1467
Objective To investigate the efficacy of gelatin sponge particles(GSP)or polyvinyl alcohol particles (PVA) for hemoptysis secondary to bronchiectasis or pulmonary tuberculosis. Methods The clinical data on 271 patients with bronchiectasis- or tuberculosis-induced hemoptysis were retrospectively analyzed. The efficacy and rates of recurrence and complications were analyzed. Results A total 271 patients were included in this study, 176 of whom suffered from bronchiectasis and the rest 95 had tuberculosis. One-week cure rate was signifi-cantly higher in bronchiectasis group than in tuberculosis group(73.3%vs. 46.3%,P<0.05),and one-year recur-rence rate was significantly lower in bronchiectasis group(17.6%vs. 26.3%,P<0.05). One-year recurrence rate was slightly higher in patients receiving GSP than in those undergoing PVA(bronchiectasis group:22.2%vs. 10.3%, P<0.05;tuberculosis group:28.8%vs. 22.2%,P>0.05). No severe complications occurred. Conclusions In-terventional artery embolization therapy for hemoptysis secondary to bronchiectasis is better than tuberculosis-induced hemoptysis,and PVA is more effective than GSP. Recurrence of massive hemoptysis mostly occurrs within one month ,and most of the patients are complicated with blood supply and have a history of hemoptysis.
9.Hepatitis B virus reactivation in HBV DNA-negative patients with hepatocellular carcinoma after transarterial chemoembolization
Kai WANG ; Caifang NI ; Guomin JIANG ; Yizhi LIU
Chinese Journal of Hepatobiliary Surgery 2017;23(3):166-168
Objective To evaluate risk factors of hepatitis B virus (HBV) reactivation after transarterial chemoembolization (TACE) in patients with HBV-related hepatocellular carcinoma (HCC) with undetectable HBV DNA levels.Methods From August 2012 to Sepemter 2015,all patients who underwent TACE for HBV-related HCC with HBV DNA level less than 103 copies/ml in the First Affiliated Hospital of Soochow University were enrolled into the study.These patients were followed-up for at least 6 months after TACE to assess HBV reactivation.Univariate and multivariate logistic regression analyses were done to evaluate the risk factors related to HBV reactivation in these patients.Results With predetermined inclusion and exclusion criteria,99 patients were enrolled into the study.Twenty-four patients (24.2%) developed HBV reactivation after TACE in the followed-up period.The level of transaminase was significantly higher in the HBV reactivation group than the non HBV reactivation group (P < 0.05).HBeAg positivity and tumors more than 3 in number were independent risk factors of HBV reactivation.Conclusion HCC patients with undetectable levels of HBV DNA had a significant risk of HBV reactivation after TACE.
10.Treatment of velopharyngeal insufficiency with a modified pharyngngeal flap
Guomin WANG ; Yushen YANG ; Liping JIANG ; Yousheng TANG ; Longhao YAO
Journal of Practical Stomatology 2000;0(06):-
Objective:To study the a feasibility of modified pharyngoplasty in the treatment of velopharyngeal insufficiency.Methods:30 cases of velopharyngeal insufficiency were treated with a modified pharyngoplasty followed by speech training.The effects of the treatment were evaluated by blowing test (BT),chinese articulation inteligibility test (CIT) and hypernasality observation(HO).Results:Before and after treatment BT was 1~26 and 8~40,CIT(%) 20~60 and 47~82,HO(cases) 30 and 3,respectively.Conclusions:The modified pharyngoplastic surgery is feasible in the treatment of velophayngeal insufficiency.