1.Analysis of curative effect of shenmai in treatment female patients with coronany heart disease
Xiaomei SUN ; Guangxian MA ; Guoling YAO
Chinese Journal of Primary Medicine and Pharmacy 2012;19(9):1306-1307
Objective To understand the effect of shenmai in treatment female patients with coronany heart disease.Methods 53 female patients with coronany heart disease were randomly divided into 2 groups(group A with normal treatment and shenmai,group B with normal treatment and water-soluble vitamins.Clinical effect was observed after 2 weeks.Results There are 13 cases effective in group A and 9 cases effective in group B,and the difference between the two groups is statistically significant (P < 0.05).Conclusion It's better for female patients to uss shenmai.
2.Correlation of coronary heart diseases with endogenous androgen level
Guoling YAO ; Hui JANG ; Chunde ZHANG
Chinese Journal of Primary Medicine and Pharmacy 2014;21(2):181-183
Objective To investigate the relationship between elderly male patients with coronary heart diseases (CHD) and endogenous androgen level and other related factors.Methods 28 male patients with acute coronary syndrome (ACS) were chosen as research group,28 male patients with stable angina pectoris (SAP) were chosen as observation group,and 28 healthy male people were selected as control group.All of three groups were checked by carotid artery Doppler ultrasonography and the peripheral blood concentration of testosterone (T),TC,LDL-C,Glu,CRP were measured,BMI was calculated in all three groups.Results Peripheral blood concentration of T,TC,LDL-C,Glu in ACS group and SAP group were significantly higher than those of the control group(P <0.05).IMT and number,quality of plaque in patients with ACS and SAP were significantly different compared with the control group (P < 0.05).T,Tc,LDL-C,CRP,BMI,IMT,unstable plaque were significantly different between ACS group and SAP group(P < 0.05).Glu had no statistical difference between ACS group and SAP group (P > 0.05).Conclusion Peripheral blood concentration of T was negatively correlated with arterosclerosis,unstable plaque,Tc,LDL-C,BMI in old male CHD patients
3.Prediction of H7N9 epidemic in China.
Zhaojie ZHANG ; Yao XIA ; Yi LU ; Jingchao YANG ; Luwen ZHANG ; Hui SU ; Lili LIN ; Guoling WANG ; Tongmei WANG ; Shao LIN ; Zhongmin GUO ; Jiahai LU
Chinese Medical Journal 2014;127(2):254-260
BACKGROUNDIn March 2013, human cases of infection with a novel A (H7N9) influenza virus emerged in China. The epidemic spread quickly and as of 6 May 2013, there were 129 confirmed cases. The purpose of this study was to analyze the epidemiology of the confirmed cases, determine the impacts of bird migration and temperature changes on the H7N9 epidemic, predict the future trends of the epidemic, explore the response patterns of the government and propose preventive suggestions.
METHODSThe geographic, temporal and population distribution of all cases reported up to 6 May 2013 were described from available records. Risk assessment standard was established by analysing the temperature and relative humidity records during the period of extensive outbreak in three epidemic regions in eastern China, including Shanghai, Zhejiang and Jiangsu provinces. Risk assessment maps were created by combining the bird migration routes in eastern China with the monthly average temperatures from May 1993 to December 2012 nationwide.
RESULTSAmong the confirmed cases, there were more men than women, and 50.4% were elderly adults (age >61 years). The major demographic groups were retirees and farmers. The temperature on the days of disease onset was concentrated in the range of 9°C-19°C; we defined 9°C-19°C as the high-risk temperature range, 0°C-9°C or 19°C-25°C as medium risk and <0°C or >25°C as low risk. The relative humidity on the days of disease onset ranged widely from 25% to 99%, but did not correlate with the incidence of infection. Based on the temperature analysis and the eastern bird migration routes, we predicted that after May, the high-risk region would move to the northeast and inland, while after September, it would move back to north China.
CONCLUSIONSTemperature and bird migration strongly influence the spread of the H7N9 virus. In order to control the H7N9 epidemic effectively, Chinese authorities should strengthen the surveillance of migrating birds, increase poultry and environmental sampling, improve live poultry selling and husbandry patterns and move from a "passive response pattern" to an "active response pattern" in focused preventive measures.
Animals ; Birds ; China ; epidemiology ; Influenza A Virus, H7N9 Subtype ; pathogenicity ; Influenza in Birds ; epidemiology ; Temperature