Clinical nutrition, medical treatment and nursing constitute the three pillars in searching for the best curative effect. In view of the fact that the management and overall construction of the nutrition department seriously lags behind medical and nursing work, which impairs the quality and image of the hospital and hinders its overall development, the authors, basing themselves on the realities and having their eyes on the future, explore the overall construction of the nutrition department from the perspectives of disciplinary orientation identification, management system, personnel training, and hardware construction. They argue that the key to the construction of the nutrition department lies in identifying disciplinary orientations and implementing policy favor; carrying out the manning quotas and laying solid organizational foundations; strengthening personnel training and grasping key development opportunities; streamlining the management system and safeguarding a healthy development.

To investigate the correlation between cerebral infarction and carotid atherosclerosis.Methods:Bilateral carotid atherosclerotic plaques,intima-media thickness (IMT),and stiffness coefficient (β) in 60 patients with cerebral infarction were detected by high-frequency color Doppler imaging,and they were compared with the control group (n=60).Results:The detection rate of plaque in the cerebral infarction group was significantly higher than that in the control group (90% vs 28%,P<0.005); the constituent ratio of soft plaques in the cerebral infarction group was significantly higher than that in the control group (P <0.01),and the constituent ratio of flat and hard plaques was significantly lower than that in the control group (P<0.005); IMT and β values in the cerebral infarction group were significantly higher than those in the control group (P<0.01).Furthermore,IMT had significant positive correlation with β values (P<0.01).Conclusions:Carotid atherosclerosis is closely correlated with cerebral infarction.

Objective:To investigate the importance and appropriate application of perioperative nutritional support in patients with obstruction caused by colon cancer.Methods:19 patients received parenteral or enteral nutritional support in the period of perioperation.When nutrition was applied,the nutritional indices,liver function and renal function were observed.Results:Hb,blood K~(+) and Na~(+) were significantly increased after nutritional support.The nutritional indices did not change and were kept within normal range during nutrition.Conclusion:The nutritional support is one of the important perioperative treatments in patients with obstruction caused by colon cancer.

Objective: The purpose of this study was to further investigate other effects of Xuezhikang Capsule than blood lipid decreasing,particularly its effect on the high sensitivity C reactive protein(Hs-CRP) in young adult patients with hyperlipemia.Methods: We treated 135 hyperlipemia patients aged 18-39 years with Xuezhikang Capsule at 0.6g tid for 8 successive weeks,followed by detection of the levels of serum Hs-CRP and blood lipid.Results: After Xuezhikang treatment,the level of serum Hs-CRP was significantly decreased in the young adult patients with hyperlipemia(P

Objectives: The research is designed to study the accuracy and characteristics of diagnostic methods for estimating the expansive type of gastric cancer in normal clinical practice, and to evaluate the clinical significance of this estimation. Methods: Preoperative Borrmann classifications of gastric cancer were diagnosed by endoscopies, barium studies and computed tomographies. The results were compared with Borrmann classifications from surgical specimens. Results:The diagnostic accuracy of endoscopy in small gastric cancers was better than that in large gastric cancers. The diagnostic accuracy of CT for type Ⅰ and Ⅳ, which have more obvious gross characteristics, was better, and for type Ⅱ and type Ⅲ, which need to be differentiated by local characteristics such as morphologic appearances of ulcers, was worse. The barium study estimated the expansive type of gastric cancer according to borders of tumors, characteristics of ulcers and whole figure, However, it was difficult to observe detailed changes. Conclusions: To improve the veracity of preoperative diagnosis for the expansive type of gastric cancer requires integrative use of endoscopies, barium studies and computed tomographies. The diagnosis of biological characteristics of gastric cancer reflects its quality, and the diagnosis of aggressive degree reflects its quantity. Only with the diagnosis of these two aspects, can we estimate the clinical pathological process of the gastric cancer completely and comprehensively, so as to select the most reasonable and desirable treatment.

Objective Cardiac valve replacement with cardiopulmonary bypass ( CPB ) can induce myocardial ischemia-reperfusion injury , which is bad for cardiac function recovery .The aim of the study was to evaluate the myocardial ischemia-reperfusion injury effect of breviscapine intravenously injected before CPB in patients undergoing cardiac valve replacement with CPB . Methods 40 patients scheduled for cardiac valve replacement were randomly divided into two groups :control group and breviscapine group ( n=20).Normal saline 15 mL and breviscapine 0.75 mg/kg was administered with pump within 30 mins after the induction of anesthesia in control group and breviscapine group respectively .Blood samples were taken from jugular vein at each of the five time points: before surgical incision (T0) and at 30mins, at 6, 12, 24h after aortic unclamping (T1-T4) for determination of plasma concentration of car-diac troponin-I (cTnI), creatine kinase isoenzyme (CK-MB) and superoxide dismutase (SOD). Results Compared with T0, the cTnI and CK-MB in both groups significantly increased at T 1-T4 and peaked at T 2 , the SOD in both groups significantly decreased at T 1-T4(P<0.05).Compared with control group, cTnI and CK-MB significantly decreased, while SOD activity significantly increased at T1-T4in breviscapine group (P<0.05). Conclusion The intravenous infusion of breviscapine 0.75 mg/kg before the staring of CPB can relieve myocardial ischemia-reperfusion injury in patients undergoing cardiac valve replacement with CPB , and the mechanism may be related to the anti-oxidative stress effect .

Objective To investigate the application of the mini nutritional assessment (MNA)in the malnutrition risk eval-uation of elderly inpatients with cardiovascular disease(CVD).Methods The MNA method was adopted to detect the MNA scores in 316 elderly inpatients with CVD.The inpatient′s nutritional status was evaluated according to the MNA scores.Results Among 316 cases,52 cases(16.46%)were malnutrition,60 cases (18.99%)had the malnutrition risk and 204 cases (64.56%)were in a good nutritional status;the occurrence rate of malnutrition and malnutrition risk in the female elderly patients were higher than those in the male patients,the differences were statistically significant(P <0.01);the occurrence rate of malnutrition and malnutri-tion risk in the elderly inpatients(≥80 years old)were higher than those in the low age patients(60~<80 years old),but the differ-ences had no statistical significance(P >0.05);the occurrence rate of malnutrition and malnutrition risk in the rural patients were higher than those in the patients lived in city,the differences were statistically significant(P <0.05).Conclusion Elderly inpatients with CVD have the higher prevalence of the malnutrition risk,the MNA can be applied in elderly inpatients with CVD for conduc-ting the nutritional status monitoring and early screening the malnutrition risk.

Objective:To investigate the role of apoptosis-associated speck-like protein(ASC) in non-apoptotic,non-necrotic cell death of neutrophils induced by ONO-AE-248.Methods:The morphological changes of neutrophil nuclei and DNA fragmentation of the cells were examined by confocal microscopy and terminal-deoxynucleotidyl transferase mediated nick end labeling(TUNEL).Neutrophils were stimulated with medium alone,LPS,TNF-? or ONO-AE248 respectively.Then expression of ASC was detected by Western blot.Results:ONO-AE-248-induced neutrophil death was negative in TUNEL assay.Western blot showed that the expression of ASC protein was down-regulated by ONO-AE-248.Conclusion:The DNA degradation of the neutrophils when stimulated by ONO-AE-248 is probably different from that of the typical apoptosis.ASC might be a crosslink point between the ONO-AE-248-induced neutrophil death and spontaneous apoptosis of neutrophils.