1.The research in the changes of design in the history taking exam of Phased Empirical Medical Licensing Examination
Chinese Journal of Medical Education Research 2016;15(5):437-440
History taking capability is a basic skill of clinician.During the Phased Empirical Research,NMEC redesigned the test station of History taking.On the basis of the same inquiry,we use SP,enlarge the question amount,score value,exam time,and also add the evaluation of comprehensive quality.By the new test,we can measure the history taking skill,communication talent and medical humanity competence of medical students.This paper raises a claim on humanistic quality education of medical students in order to prompt medical education to attach importance to the cultivation of medical humanity competence,to improve the medical humanistic education model,then improve the overall quality of medical students.
2.Problems and Countermeasure of IntroducingMedical Social Workers to Hospitals
Chinese Medical Ethics 2016;29(4):665-667
In China, health care system is not perfect,the trust is lack between doctors and patients. Introdu-cing medical social workers to hospitals is to manage social resources as a whole, optimize medical treatment service process,enhance the quality of medical service, and relieve the pressure of doctors and nurses. Under this back-ground, this paper gave an overview of the medical social work and its contents. Then, it analyzed the necessity of introducing medical social workers to hospitals and pointed out the existing plight of medical social work. Finally, it put forward the suggestions and countermeasures to promote medical social work.
3.Enhancement of tendon-bone healing of rotator cuff with recombinant human bone morphogenetic protein-2 in rabbits:a histological and biomechanical study
Guojian FU ; Anmin JIN ; Li ZHANG
Orthopedic Journal of China 2006;0(10):-
[Objective]To evaluate the effectiveness of recombinant human bone morphogenetic protein-2 in the repair of rabbit rotator cuff injury.[Method]Forty-eight male New Zealand rabbits,aged 8 months,received an rotator cuff acute injury and reconstruction of the insertion of supraspinatus tendon on greater tuberosity of humerus.The rabbits were randomly divided into 3 groups postoperatively:(1) rhBMP-2 group:fibrin sealant(FS) containing rhBMP-2 was applied to the interface between the bone-tendon interface; (2)FS control group:only FS was applied;(3)blank control group:untreated after the surgery.Harvested 36 specimens underwent biomechanical analysis at the 2nd,4th,8th postoperative weeks respectively.Harvested 12 specimens underwent histological analysis at the 8th postoperative week.[Result]Histological examination showed that Sharpey's fibers were found in the interface with the formation of four-layer indirect insertion in the rhBMP-2 group at the 8th postoperative week.In the FS control group and blank group,the tendon-bone interface was filled with granulation tissue and part of Sharpey's fibers and the newly generated bone tissue.Biomechanical analysis displayed that the tensile strength and stiffness of bone-tendon interface increased time-dependently in all groups,and it in the rhBMP-2 group was significantly higher than those in the other two groups at any time-points (both P
4.Evaluation of Residues of Chrysanthemum Ester Pesticides and Heavy Metals in Oolong Tea Samples
Wei HUANG ; Guojian LI ; Dongxing YUAN
Journal of Environment and Health 1992;0(02):-
Objective To analyze the residues of chrysanthemum ester pesticides and heavy metals in several typical Oolong tea samples for evaluating the drink safety. Methods The residues of chrysanthemum ester pesticides in the tea samples were extracted with ultrasonic method. Gas chromatography equipped with ECD was applied to determine the pesticide residues. The heavy metals in tea samples were analyzed with an inductively coupled plasma-mass spectrometer (ICP-Mass) and an atomic fluorescence spectrometer. Results The residues of chrysanthemum ester pesticides in the dry tea samples were 0.200-0.780 mg/kg, no residues was detected in the tea water. The content of heavy metals in the dry tea and tea water was very low, under the standard limits. Conclusion The Oolong tea samples chosen in the present investigation have not been polluted by chrysanthemum ester pesticides and heavy metals, according to the results, the Oolong tea made in the area is safe for drink.
5.Insertion of Inferior Vena Cave Filter in Treating Lower Extremity Deep Venous Thrombosis
Guojian LI ; Guokai YANG ; Xiaoming HE ; Ping LU ; Yong YANG
Chinese Journal of Bases and Clinics in General Surgery 2008;0(11):-
Objective To discuss and evaluate the value of insertion of inferior vena cava filter in treating lower extremity deep venous thrombosis(DVT).Methods Inferior vena cava filters were placed in 46 patients with lower extremity DVT prior treatment,20 in which were treated by therapy with anticoagulation and thrombolysis,and therapy with pressure gradient,and the other 26 patients by operation and thrombolysis therapy,and therapy with pressure gradient.Whether patients occurred pulmonary embolism was observed and the form and site of filters were monitored by periodic fluoroscopy.Results Inferior vena cava filters were placed successfully in all patients,38 cases were implanted permanence inferior vena cava filter,8 cases were implanted temporary inferior vena cava filter.Symptoms and signs of DVT disappeared or remitted in 44/46 patients after treatment.None of pulmonary embolism was occurred.Follow up 2-24 months(average 13 months) for 36 cases with permanence inferior vena cava filter,there was no complication of the filter and pulmonary embolism occurred.Conclusions The method of inserting inferior vena cava filter is simple and safe,which can prevent pulmonary embolism effectually to offer sufficient safeguard for the treatment of DVT.
6.The inspiration of the Chinese clinical medical national licensing examination on the medical educational reform in China
Yuan ZHAO ; Guojian LI ; Rui GAO ; Xiancheng WANG
Chinese Journal of Medical Education Research 2015;(1):52-54,55
The Chinese clinical medical national licensing examination is the profession ad-mittance exam, which is undertake the responsibility of selecting qualified physicians. It also promotes the medical education in China. The standard for examination, the examination content, methods for measuring the Chinese clinical medical national licensing examination as well as the reform and de-velopment, has a certaln guiding role to China's medical education and medical education reform. While reviewing the medical students' performance in the examination, we can discover the weakness in medical education, which is then conducive to the promotion of teaching reform and innovation. The competence based medical licensing examination reform in China, advocating the cultivation of clinical comprehensive ability as the core content to tralning and evaluating, is conducive to continuously im-proving the quality of medical education in China, and to tralning more qualified physicians in the country.
7.Radiosensitization of cyclooxygenase-2 selective inhibitor NS-398 in esophageal carcinoma cell and its mechanism
Shengbao LI ; Qingming WU ; Xiaohu WANG ; Guojian XIE
Chinese Journal of Radiation Oncology 1992;0(04):-
Objective Objective To study the influence of NS-398,a selective cyclooxygenase-2 inhibitor on the radiosensitivity of human esophageal carcinoma cell line EC9706 cell. Methods EC9706 cell, highly expressing COX-2, had been incubated with NS-398 at 10、20、50 and 100??mol/L for 24?h or 48?h before irradiation ranging from 0 to 10?Gy. Cell survival was measured by a standard clonogenic assay after 8 days of incubation. Apoptotic percentage was measured by FCM and DNA fragmentation by agarose electrophronesis. Results The senstization enhancement ratios (ratio of D_q) in EC9706 cell were 1.11, 1.24, 1.40, 1.54 at 10, 20, 50, 100??mol/L of NS-398 for 24?h pre-incubation and 1.11, 1.27, 1.58, 1.67 for 48?h pre-incubation, which showed a dose-dependant and time-dependant manner. FCM analysis revealed a higher sub-G_1 cell peak in NS-398 group after irradiation. Agarose electrophronesis showed a marked ladder. Radiation-induced apoptosis was enhanced by NS-398 (P
8.Discussion on astronomical background of yiyi calenders chronological era by heavenly stems and earthly branches
Jiucheng JIN ; Guojian GAO ; Hao JIN ; Ren LI
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(05):-
The traditional Chinese medicine deduces the 'Tianshi'based on the chronological era by heavenly stems and earthly branches,whose mechanism has been an eternal mystery.The references discussed the astronomical background of the chronological record of years by heavenly stems and earthly branches.In this paper,① A new law of the nature and human body is unitied was discovered.The relative position of the diurnal motion of the sun and the motion of five yao observed from the earth repeated with a precise period of 60 years,(1years,=360days).It lead the discussion of astronomical background for the chronological record of days and shichen by heavenly stems and earthly branches.② The yiyi calendar's chronological record of months by heavenly stems and earthly branches had the same astronomical background as the chronological record of years,i.e.the relative positions of yearly motion of the sun,the synodic month and the motion of five yao observed from the earth had an approximate cycle time of 60 years.③ The paper further discovered that the relative positions of the diurnal and yearly motion of the sun,the synodic month and the motion of five yao observed from the earth repeated every 240 years.This indicated the astronomical background for the fact that the yiyi calendar's sizhu heavenly stems and earthly branches group had a cycle time of 240 years.④ The traditional Chinese medicine should use the yiyi calendar's local time.
9.Influence of swimming training on the expression of nerve growth factor and neurotrophins-3 in rats with cerebral infarction
Guojian SUN ; Junting MA ; Zhanbiao LI ; Qiang WANG
Chinese Journal of Physical Medicine and Rehabilitation 2015;37(8):561-564
Objective To observe the influence of swimming training on the expression of nerve growth factor (NGF) and neurotrophins-3 (NT-3) in rats with cerebral infarction,and to explore the underlying neuroprotection mechanism of exercise training on cerebral infarction.Methods Forty-five healthy male Sprague-Dawley rats were randomly divided into a sham-operation group,a control group and a training group,with 15 rats in each group.Each group was further divided into a 3-day,7-day and 14-day subgroups,which amounts to 9 groups.To establish animal model of cerebral ischemia-reperfusion in rats,the intraluminal thread method was applied to cause left middle cerebral artery occlusion (MCAO) for 2 h before reperfusion.The rats of the training group were given swimming training for 10 min,once daily,while those of the sham-operation and control groups were not given any training.Neurological deficits were assessed using Bederson scores.The expression of NGF mRNA and NT-3 mRNA in the ischemiareperfusion pallium was examined using reverse transcription-polymerase chain reaction (RT-PCR).Results The rats of the sham-operation group showed no neurological deficits.At the same time points,the average Bederson scores of the training group were significantly lower than the control group,but significantly higher than the sham group.Moreover,the 14 d training group had the lowest Bederson score (1.20 ±0.45),compared to the value 3 and 7 days after modeling.The expression of NGF mRNA and NT-3 mRNA of ischemic cerebral cortex in the training group was significantly improved when compared to the sham-operation group or the control group.On day 14,the expression of the NGF mRNA (0.66 ± 0.07),and the NT-3 mRNA (0.79 ± 0.06),were significantly higher than those on day 3 and 7.Conclusions Swimming training could increase the expressions of NGF mRNA and NT-3 mRNA in the ischemic cerebral cortex.It might be one of the key mechanisms that exercise training could promote the recovery of damaged neurological function in rats with cerebral infarction.
10.A preliminary study on the relationship between the length of A2 type objective test questions and the degree of difficulty and discriminative power in medical examination
Guojian LI ; Ju HE ; Yimin DING ; Dongqi ZHANG
Chinese Journal of Medical Education Research 2017;16(7):653-656
Objective In a large-scale clinical medical examination, A2 type best multiple-choice test questions to the same knowledge were used respectively in simple and complex form, to compare the difficulty and discrimination indices of the two forms of test questions and provide evidence to the improve-ment of clinical medical examination. Method In a large-scale clinical medical examination more than 4000 candidates participated, and 20 questions to different knowledge points were randomly selected and used in the examination respectively in simple and complex A2 type best multiple-choice test questions. The difficulty and discrimination indices of the two forms of test questions were compared. Results The average difficulty coefficient of the 20 simple test questions (65.5 words per question in average) is 0.6829, and the average discriminative powers are 0.2675 and 0.2579 respectively using identification index method and point biserial correlation method. The average difficulty coefficient of the 20 complex test ques-tions (135.5 words per question in average) is 0.7095, and the average discriminative powers are 0.3065 and 0.2967 respectively using identification index method and point biserial correlation method. Conclusion To the same knowledge points, the average difficulty of complex A2 type best multiple-choice test questions is slightly lower than the simple ones, while the average discriminative power is increased in the complex questions. The complex A2 type test questions are of higher quality and more in line with the requirements of the medical entrance examination, medical education and examination reform.