Objective To explore the effect of positive pressure sealing intravenous indwelling catheter in the hepatocirrhosis patients by the Salvia lyophilized dilution in the apparatus infusionis .Methods Two hundred and one hepatocirrhosis patients with intravenous indwelling catheter were chosen and divided into three groups according to the random number table , each with 67 cases.The control group received the traditional positive pressure sealing tube through heparin solution (5 ml, 50 U/ml), and the test group 1 received the positive pressure sealing tube through Salvia lyophilized dilution (5 ml), and the test group 2 received the direct positive pressure sealing tube through the Salvia lyophilized dilution ( 5 ml, 4 mg/ml ) in the apparatus infusionis.The coagulation function, the rate of jamming, bleeding tendency, incidence rate and the average time of sealing tube of phlebitis were compared among three groups before the indwelling catheter and after the extubation catheter .Results The rates of jamming were respectively 6.2%, 10.8% and 7.6% in the control group, the test group 1 and 2, and the incidence rates of bleeding tendency were respectively 12.3%, 6.2%, and 13.8%, the incidence rates of phlebitis were respectively 9.2%, 4.6% and 7.7%, and the differences were not statistically significant (χ2 =0.83, 0.40, 0.48, respectively;P>0.05).The prothrombin time were respectively (18.16 ±4.82)s, (17.64 ±3.96)s, (17.28 ±3.89)s in the control group, the test group 1 and 2, and the differences were not statistically significant (F=0.71,P>0.05).The average time of sealing tube was (49.26 ±4.78)s in the test group 1, and was (33.41 ±3.91)s in the test group 2, and the difference was statistically significant (t=40.66,P <0.01).Conclusions Three kinds of methods of sealing intravenous indwelling catheter are safe and effective .The application of the direct positive pressure sealing tube through the Salvia lyophilized dilution in the apparatus infusionis can optimize nursing process , and relieve the economic burden of patients , their families and the society , and is worthy of the clinical promotion .

Lower extremity deep vein thrombosis (DVT) is one of the main complications in patients with traumatic fractures, and for severe patients, the DVT can even affect arterial blood supply, resulting in insufficient limb blood supply. If the thrombus breaks off, pulmonary embolism may occur, with a high mortality. The treatment and rehabilitation strategies of thrombosis in patients with lower extremity fractures have its particularity. DVT in traumatic fractures patients has attracted extensive attention and been largely studied, and the measures for prevention and treatment of DVT are constantly developing. In recent years, a series of thrombosis prevention and treatment guidelines have been updated at home and abroad, but there are still many doubts about the prevention and treatment of DVT in patients with different traumatic fractures. Accordingly, on the basis of summarizing the latest evidence-based medical evidence at home and abroad and the clinical experience of the majority of experts, the authors summarize the clinical treatment and prevention protocols for DVT in patients with traumatic fractures, and make this consensus on the examination and assessment, treatment, prevention and preventive measures for DVT in patients with different fractures so as to provide a practicable approach suitable for China ′s national conditions and improve the prognosis and the life quality of patients.

Chronic refractory wound (CRW) is one of the most challengeable issues in clinic due to complex pathogenesis, long course of disease and poor prognosis. Experts need to conduct systematic summary for the diagnosis and treatment of CRW due to complex pathogenesis and poor prognosis, and standard guidelines for the diagnosis and treatment of CRW should be created. The Guideline forthe diagnosis and treatment of chronic refractory wounds in orthopedic trauma patients ( version 2023) was created by the expert group organized by the Chinese Association of Orthopedic Surgeons, Chinese Orthopedic Association, Chinese Society of Traumatology, and Trauma Orthopedics and Multiple Traumatology Group of Emergency Resuscitation Committee of Chinese Medical Doctor Association after the clinical problems were chosen based on demand-driven principles and principles of evidence-based medicine. The guideline systematically elaborated CRW from aspects of the epidemiology, diagnosis, treatment, postoperative management, complication prevention and comorbidity management, and rehabilitation and health education, and 9 recommendations were finally proposed to provide a reliable clinical reference for the diagnosis and treatment of CRW.

Since December 2019, novel coronavirus pneumonia (NCP) has been reported in Wuhan, Hubei Province, and spreads rapidly to all through Hubei Province and even to the whole country. The virus is 2019 novel coronavirus (2019-nCoV), never been seen previously in human, but all the population is generally susceptible. The virus spreads through many ways and is highly infectious, which brings great difficulties to the prevention and control of NCP. Based on the needs of orthopedic trauma patients for emergency surgery and review of the latest NCP diagnosis and treatment strategy and the latest principles and principles of evidence-based medicine in traumatic orthopedics, the authors put forward this expert consensus to systematically standardize the clinical pathway and protective measures of emergency surgery for orthopedic trauma patients during prevention and control of NCP and provide reference for the emergency surgical treatment of orthopedic trauma patients in hospitals at all levels.