1.An Effervescent Disinfection Tablet with Low Chlorine Smell: Its R&D
Xuelian BIAN ; Shifang YU ; Guohui YANG ; Hui REN
Chinese Journal of Nosocomiology 2006;0(08):-
OBJECTIVE To study and develop an effervescent disinfection tablet with low chlorine smell.METHODS The specially tiny smashing technology and the high molecular complexon technology were applied to make the tablet after mixing the complex organic chlorine powder made by a special technoloy with the effervescent agent.RESULTS No chlorine was detected by examining the disinfection solution with 4000 mg/L available chlorine,but it was 0.997 mg/m3 for the symclosene(trichloroisocyanuric acid) disinfection tablet.The sterilization,toxicology,sanitary examination,etc all met the disinfectant standards made by the Ministry of Health.CONCLUSIONS "Aiershi" brand disinfection tablet is one kind of disinfectants with low chlorine smell.Its compound disinfection fluid,is without chlorine smell nearly.It is unharmful to the human body and the environment.And it highly praises by thousand hospitals using it for more than two years.It has been one of items of scientific and technological achievement of Shanghai municipal government.The use of low chlorine disinfection tablet could be expanded.
2.Overexpression of p21 Has Inhibitory Effect on Human Hematopoiesis by Blocking Generation of CD43+ Cells via Cell-Cycle Regulation
Jiahui ZENG ; Huifang ZHANG ; Yuanling LIU ; Wencui SUN ; Danying YI ; Lijiao ZHU ; Yonggang ZHANG ; Xu PAN ; Yijing CHEN ; Ya ZHOU ; Guohui BIAN ; Mowen LAI ; Qiongxiu ZHOU ; Jiaxin LIU ; Bo CHEN ; Feng MA
International Journal of Stem Cells 2020;13(2):202-211
Background and Objectives:
p21, an important member of the Cip/Kip family, is involved in inhibitory effects of RUNX1b overexpression during the early stage of human hematopoiesis.
Methods:
and Results: We established a human embryonic stem cell (hESC) line with inducible expression of p21 (p21/hESCs). Overexpression of p21 did not influence either mesoderm induction or emergence of CD34+ cells, but it significantly decreased the production of CD43+ cells and changed the expression profile of hematopoiesis-related factors, leading to the negative effects of p21 on hematopoiesis.
Conclusions
In RUNX1b/hESC co-cultures when RUNX1b was induced from D0, perturbation of the cell cycle caused by upregulation of p21 probably prevented the appearance of CD43+ cells, but not CD34+ cells. The mechanisms via which CD34+ cells are blocked by RUNX1b overexpression remain to be elucidated.
3.Key technologies in digital breast tomosynthesis system:theory, design, and optimization.
Mingqiang LI ; Kun MA ; Xi TAO ; Yongbo WANG ; Ji HE ; Ziquan WEI ; Geofeng CHEN ; Sui LI ; Dong ZENG ; Zhaoying BIAN ; Guohui WU ; Shan LIAO ; Jianhua MA
Journal of Southern Medical University 2019;39(2):192-200
OBJECTIVE:
To develop a digital breast tomosynthesis (DBT) imaging system with optimizes imaging chain.
METHODS:
Based on 3D tomography and DBT imaging scanning, we analyzed the methods for projection data correction, geometric correction, projection enhancement, filter modulation, and image reconstruction, and established a hardware testing platform. In the experiment, the standard ACR phantom and high-resolution phantom were used to evaluate the system stability and noise level. The patient projection data of commercial equipment was used to test the effect of the imaging algorithm.
RESULTS:
In the high-resolution phantom study, the line pairs were clear without confusing artifacts in the images reconstructed with the geometric correction parameters. In ACR phantom study, the calcified foci, cysts, and fibrous structures were more clearly defined in the reconstructed images after filtering and modulation. The patient data study showed a high contrast between tissues, and the lesions were more clearly displayed in the reconstructed image.
CONCLUSIONS
This DBT imaging system can be used for mammary tomography with an image quality comparable to that of commercial DBT systems to facilitate imaging diagnosis of breast diseases.
Algorithms
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Artifacts
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Breast
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diagnostic imaging
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Female
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Humans
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Mammography
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methods
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Phantoms, Imaging
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Radiographic Image Enhancement
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methods