Objective To evaluate clinical curative effect of debonding debridement trigonum submentale with needle-knife on vertebro-basilar artery insufficiency (VBI). Methods 131 cases of VBI sufferers were randomly recruited into a control group (63 cases) and a treatment group (68 cases). The treatment group was treated by debonding debridement trigonum submentale with needle-knife; while the control group was treated with puerarin intravenous injection. Observed the changes of clinical symptoms before and after the treatment and examine changes of average of blood flowing speed in left vertebral artery, right vertebral artery, and basilar artery by TCD. Results The total effective rate was 89.71% and 85.71% in the treatment group and the control group respectively. Blood flowing speed of the left vertebral artery, right vertebral artery,and basilar artery average showed remarkable change (P＜0.01) after the treatment in the treatment group,, whose effects were better than the control group (P＜0.05). Conclusion Debonding debridement trigonum submentale with needle-knife has remarkable curative effects on VBI.

Objective To investigate the clinical effect of treating avascular necrosis of femoral head with comprehensive therapy dominated by medical ozone. Methods Joint cavity of femoral articulation was performed blockage and injected with fluids for eliminating inflammation and reliving pain. After 5 to 10 minutes interval, if the patients did not show any abnormal reaction, medical Ozone with the concentration of 30%, 8 to 10ml, was injected to the joint cavity. Meanwhile, needle-knife therapy was used to reduce pressure inside the cavity. Traditional Chinese medicine was also used for the treatment. Results of all 183 femoral articulations of 135 cases, the therapeutic result of 38 articulations perfect, occupying 20.8% (38/183), 88 were good, occupying 48.1% (88/183), 31 were normal, occupying 16.9% (31/183) and 26 were bad, occupying 14.2% (26/183).The total effective rate was 85.8% (157/183). Conclusion The treatment of avascular necrosis of femoral head with comprehensive therapy dominated by medical ozone had outstanding therapeutic effects.

Objective To explore clinical significance of controlled mechanical ventilation under general anesthesia with blood gas analysis. Methods 90 adult patients who received operation under general anesthesia were ysis was made 30 min after anesthesia and per hour thereafter. The patients whose first arterial blood gas values were abnormal were made another blood gas analysis 25 min after adjusting their respiratory parameters. Results The fist blood gas analysis values of the patients showed that the average PaCO2 value was ( 33.6 ± 12.9 ) mm Hg, only 40. 0% were normal;The average pH value was(7.40 ±0.05) ,66.7% were normal. Ventilation parameters of 36 cases whose first PaCO2 were abnormal were adjusted according to their first PaCO2. The average PaCO2 value of the second blood gas analysis was ( 37. 1 ± 4.6) mm Hg,90. 0% were normal and higher than the first ( P < 0. 05 ). The average pH value was (7.38 ± 0. 02 ),91.1% were normal and it was higher than the first( P < 0. 05). Conclusion It was important for arterial blood gas analysis to direct controlled respiration under general anesthesia.

Objective: To compare body composition of girls aged 10 to 15 years with or without onset of menarche in Nanyang, and to provide a reliable basis for effective adolescent health care. Methods: From August to December 2020 and from March to October 2021, cluster random sampling was adopted in 13 areas of Nanyang City to select 1 523 girls. Questionnaire survey and body composition (Japan Bailida MC-180) were conducted. Results: BMI, body fat percentage, trunk fat percentage, muscle mass and bone mass of girls aged 10 to 15 years in Nanyang City gradually increased with age, the water content in the body decreased with age. BMI, fat percentage, trunk fat percentage, muscle mass and bone mass in girls experienced menarche were higher, while water content in the body was lower than those without menarche. Significant difference in BMI between the menarche and without menarche of girls were found in those aged 11 to 15 years( t =2.07, 2.03, 2.43, 2.45, 2.52, P <0.05). Significant differences in fat rate, trunk fat rate, muscle mass and bone mass between the menarche and without menarche were found in girls aged 12 to 15 years fat percentage, trunk fat percentage muscle mass bone mass( P <0.05). Among girls aged 10, 14 and 15 year old, significant difference in body water percentage were observed in the two groups of girls with or without menarche( t =2.75, 2.35, 2.37 , P <0.05). Average age at menarche showed significant urban rural differences among girls aged 10, 11 and 14 year old ( χ 2=4.34, 3.45, 6.73, P <0.05). Conclusion Changes in body composition including BMI, body fat percentage, muscle mass, bone mass and body water percentage during the transition to menarche in girls is helpful to predict menarche in girls. Age of menarche is related to nutritional status, BMI, physical exercise, snack and beverage intake.

BACKGROUND:The displacement change parameters of the bone structure of the first metatarsal bone at the two-dimensional level of hallux valgus deformity are of great significance for clinical diagnosis and treatment,while the quantitative analysis of the three-dimensional deformity index may have some influences on the postoperative efficacy. OBJECTIVE:To explore the quantitative change of the three-dimensional deformity index of the first metatarsal bone after routine osteotomy and orthosis for hallux valgus deformity and to provide reference for clinical work. METHODS:100 patients with hallux valgus deformity(foot)in Hengshui People's Hospital from October 2020 to April 2023 were selected and all of them underwent conventional osteotomy and orthosis.Foot function was assessed by the American Orthopedic Foot and Ankle Society Ankle-Hindfoot Scale 6 months after surgery.Anterolateral X-rays of the foot in weight-bearing position and CT images in simulated weight-bearing position were taken before surgery and 6 months after surgery.The three-dimensional deformity indexes of the first metatarsal bone before and after surgery were quantitatively analyzed in patients with different ages,genders and therapeutic effects,including first-second intermetatarsal angle,hallux valgus angle,distal metatarsal articular angle,tibial sesamaid position,and first metatarsal rotation α angle.The value of the difference of three-dimensional deformity indexes of the first metatarsal bone before and after operation in evaluating the curative effect was analyzed. RESULTS AND CONCLUSION:(1)Six months after operation,the American Orthopedic Foot and Ankle Society score was 75-98(88.25±4.14)points,among which 56 cases were excellent,28 cases were good,14 cases were average,and 2 cases were poor.The excellent and good rate was 84%(84/100).(2)Compared with the preoperative results,first-second intermetatarsal angle,hallux valgus angle,distal metatarsal articular angle,tibial sesamaid position,and first metatarsal rotation α angle were significantly improved in patients of different ages and genders 6 months after surgery(P<0.05).First-second intermetatarsal angle,hallux valgus angle,distal metatarsal articular angle,tibial sesamaid position,and first metatarsal rotation α angle were all lower in patients with good curative effect 6 months after surgery than those with poor curative effect,and the difference before and after surgery was greater than those with poor curative effect(P<0.05).(3)The area under the curve of the difference evaluation of the first metatarsal three-dimensional deformity index before and after surgery was above 0.7,and the area under the curve of the combined evaluation of all indexes was the largest(0.902),which was significantly greater than the first metatarsal rotation α angle and distal metatarsal articular angle(P<0.05).(4)The quantitative analysis of the three-dimensional deformity index of the first metatarsal in patients with hallux valgus deformity is related to the postoperative effect,which has important guiding significance for improving the accuracy and comprehensiveness of preoperative evaluation and improving the treatment plan.

Child ; Humans ; Case-Control Studies ; East Asian People ; Genetic Predisposition to Disease/genetics* ; Methyltransferases/genetics* ; Polymorphism, Genetic ; Wilms Tumor/pathology*