Adult ; Female ; Foreign Bodies ; surgery ; Humans ; Neck ; Oropharynx ; surgery

Dermatomyositis ; complications ; Humans ; Lung Diseases, Interstitial ; diagnosis ; etiology ; therapy

Objective To explore the effects of two air sampling methods including natural precipitation method and impacting method for detecting the bacterial count of indoor air of workplace of cosmetic plants. Methods The diameters of 44 glass bacteria-culture plates for those two sampling methods were measured. The indoor air of workplace of cosmetic plants were sampled by those two sampling methods simultaneously. The natural precipitation method was performed for 5- minute exposure ,the impacting method was performed by MAS-100 airborned bacteria sampler at flow rate of 100 L/min for 30 s,2 min,8 min respectively.All of the data on the bacterial counts of air obtained from various sampling ways were statistically analyzed.The measures for quality control of air sampling progress were put forward also. Results The diameters of 44 glass bacteria-culture plates were 8.39-8.70 cm,which were lower than the standard(9 cm?雪. The bacterial counts of air samples collected by natural precipitation method at the same location showed higher coefficient of variation,higher median,lower qualified rate compared with those by impacting method. The bacterial counts of air decreased,when the impacting sampling method was performed for 8 min continuously with sampling volume of 800 L. Conclusion The impacting method with advantages including mere influence from external environment and better precision could be primarily applied for air sampling in general condition,but it might show lower efficiency of collecting the airborne bacteria during the longer sampling period with higher sampling volume. The natural precipitation method with poor precision was suitable for longer term (8-30 min)air sampling in the relatively static environment with lower air flow and highly cleaned air. The bacterial counts of air obtained from natural precipitation method should be corrected if the diameters of glass bacteria-culture plates weren't meet the requirement of the national standard (9 cm?雪.

Objective To understand the distribution character of bacteria in the air of cosmetic workshops and present scientific data for the GMP establishment of cosmetic factories.Methods Of cosmetic factories 11 equipped with air depuration systems (ADS)(type I),13 with no ADS(type II)and 9 producing powder products (such as kermes,face mask,etc.) with no ADS(tyoe III)were chosen,distribution character of bacteria in the air was studied there.The bacteria samplings were conducted before and after operation and in winter and spring,summer and autumn respectively.Results The bacterial count in the three kinds of factories was:type I

Objective To know the air supply quality of central air-conditioning ventilation system in building before and after cleaning.Methods Three sets of central air-conditioning ventilation systems were selected from a building randomly and 3 air supply ways were selected in each system for the determination of inhalable particulate matter(PM10) and microorganisms in air before and after cleaning.Results After cleaning,the unqualified rate of air quality increased from 11.1%(before cleaning) to 77.8%.The mean value of PM10 increased from 0.051 mg/m3(before cleaning) to 0.083 mg/m3,the median of total account of bacteria and fungus increased from 150 cfu/m3 and 13 cfu/m2(before cleaning) to 570 cfu/m3 and 110 cfu/m3 respectively.Conclusion The air supply quality of central air-conditioning ventilation system in building may be damaged by cleaning if the operation is not in the right way.

Objective To explore the relationship between the tiny enhanced foci in hematoma and hematoma expansion at the acute stage of intracerebral hemorrhage (ICH).Methods CT routine and enhanced scan were applied in 36 ICH patients which onset ≤5 h,and CT examined again follow-up 1 or 2 d.The neurological function was evaluated by European Stroke Scale(ESS)at the 1st d and 21st d after onset.Results The tiny enhanced foci in hematoma were found in 11 csaes by the first CT scane.Follow up CT scane,the hematoma expansion was occurred in 10 cases,including 8 cases with tiny enhancing foci in hematoma.The incidence of hematoma expansion in ICH patients with tiny enhancing foci in hematoma(8 cases,72.7%) was significantly higher than in ICH patients without tiny enhancing foci in hematoma(2 cases,8.0%)(P

OBJECTIVE:To establish a method for the determination of 1,1-ethanediol diacetate and acetic acid in flurbiprofen axetil. METHODS:Capillary gas chromatography was performed on the column of DB-FFAP capillary column by temperature pro-grammed,the inlet temperature was 150 ℃,flame ionization detector was chosen,detector temperature was 290 ℃,carrier gas was nitrogen at a flow rate of 1.0 ml/min,injection volume was 1.0 μl,and split ratio was 5∶1. RESULTS:1,1-ethanediol diacetate and acetic acid were well-separated;and the linear ranges was 0.78-19.55 g/ml(r=0.999 7)and 7.69-64.11 μg/ml(r=0.999 3),re-spectively;the limits of quantification were 0.78 μg/ml and 7.69 μg/ml,and limits of detection were 0.23 μg/ml and 2.56 μg/ml for 1,1-ethanediol diacetate and acetic acid respectively;RSDs of precision and reprocudibility tests were lower than 3%,and stability test was lower than 5%;recoveries were 97.6%-100.4%(RSD=0.94%,n=9)and 93.6%-100.4%(RSD=0.94%,n=9);and the test results for 3 batches of flurbiprofen axetil were met the specification. CONCLUSIONS:The method is simple,accurate and re-liable,and can be used for the determination of 1,1-ethanediol diacetate and acetic acid in flurbiprofen axetil.

Objective: To investigate the efficacy, toxicity and long-term outcome of hydroxycomptothecin (HCPT) combined concurrent hyperfractionated radiotherapy for unresectable stage III non-small cell lung cancer (NSCLC). Methods: Sixty patients were enrolled into this study and divied into experimental group (n = 30) and control group (n = 30). The patients in the experimental group were administered HCPT at 10 mg/d in NS 250 mL (iv, daily) on the first 5 days and the last 5 days during radiotherapy. The patients were given concurrent hyperfractionated radiotherapy at 1.2 Gy, twice daily. The total dosage of radiation was 62.4-67.2 Gy. Patients in the control group only received hyperfractionated radiotherapy. The long-term survival rate was estimated by Kaplan-Meier survival curve. Results: Fifty-eight patients finished the trial. The follow-up rate was 96%. The response rate was 80% in the experimental group and 66.7% in the control group, respectively (P > 0.05). There was no significant difference in hematologic and non hematologic toxicities between the two groups (P > 0.05). The predicted 1- and 3-year survival rates were 77.7% and 26.1% for the experimental group and 70.3% and 15.1% for the control group, respectively. There was no significant difference between two groups (P > 0.05). Conclusion: HCPT combined concurrent hyperfractionated radiotherapy has definite effects on unresectable stage III NSCLC. The efficacy of combined therapy is better than hyperfractionated radiotherapy, and but the difference was not significant. The toxicity could be torerated.

Objective To investigate the effectiveness of glucocorticoids in the treatment of granulomatous lobular mastitis (GLM), and to discuss the optimal stage to add glucocorticoids during the treatment. Methods Twenty-four patients having received the core needle biopsy were involved. Ten cases with the explicit pathological diagnosis received the glucocorticoids therapy following the subtotal excision after remission. Pathological diagnoses of the rest 14 patients were undefined. For these 14 patients, simple partial excisions were given and the postoperative pathological diagnoses were presented as the GLM. Of all the 14 patients who accepted the surgical treatment firstly, 8 patients received the postoperative glucocorticoids adjuvant therapy. For the rest 6 patients, steroid hormone therapy was not used after surgery, and they were followed up postoperatively. All patients' clinical and pathological information were collected and analyzed. Results All patients were followed up for 6-36 months (average 18) by the outpatient service. Of all the 10 patients who received the glucocorticoids therapy before surgery, only 1 patient of them got the GLM recurrence. For the 8 patients who received the postoperative glucocorticoids treatment, only 1 patient got the recurrence. For the 6 patients who received simple partial excision, the recurrence of the GLM may be up to 3. There was no statistical difference between the two groups who both received the 05). But compared with the pure surgery treatment, the difference was obviously (P<0.05). Conclusions The clinical presentation and imaging performance of GLM are unspecific, so the diagnosis of the GLM is difficult. There is no consensus regarding the optimal treatment for GLM. The glucocorticoids therapy may be necessary preoperatively or postoperatively. For the patient with clear preoperative biopsy diagnosis, preoperative glucocorticoids adjuvant chemotherapy followed by the wide excision may be an effective method.

Objective To study the difference in clinical characteristics and experimental profiles of primary Sj gren's syndrome(pSS)with a different onset age.Methods The clinical and laboratory data of 136 pSS patients were retrospectively analyzed.Results The prevalence of anti-SSA and anti-SSB antibodies de- clined with later onset.As compared with patients with disease onset older than 45,patients with disease onset younger than 45 had higher rheumatoid factor,circulating immune complex and lower C3.The prevalence of parotitis was higher in patients with disease onset younger than 45 than those with disease onset older than 45. The two groups had similar extra-glandular involvement.Conclusion The younger onset pSS patients have more abnomlalities in inmmnological parameters,and more parotiditis,implying that young onset pSS have more strong immune responses.