1.Misdiagnosis of allergic rhinitis patients with postnasal drip
Jidong ZHANG ; Xiaoli MA ; Liying GUO
Chinese Archives of Otolaryngology-Head and Neck Surgery 2006;0(11):-
OBJECTIVE To investigate the clinical manifestation and the reasons of misdiagnosis of allergic rhinitis patients with postnasal drip. METHODS The clinical data of 3 patients with allergic rhinitis who had the symptom of postnasal dr ip and were mi sdiagnosed were s tudied. RESULTS The three patients to be misdiagnosed as chronic sinusitis treated by antibiotics drugs, post cold cough syndrome without any treatment, and chronic rhinitis treated with partial inferior turbinectomy. The 3 patients were diagnosed allergic rhinitis and cured with budesonide nasal spray. CONCLUSION The reasons of misdiagnosis are listed as follows. 1. The clinic doctors don't listen to the patient's complaint comprehensively and get incorrect information. 2. The symptoms of allergic rhinitis are not typical. 3. Postnasal drip is the main complaint and cause irritable cough, pharyngeal itching, globus. 4. The symptoms of allergic rhinitis are covered by other simultaneous diseases.
2.Hypermethylated in cancer 1 and neoplasms
Shuqin GUO ; Jingjing MA ; Yunliang ZHANG
Journal of International Oncology 2012;(12):883-886
HIC1 (hypermethylated in cancer 1) encodes a transcriptional repressor,and extensively resides in various kinds of normal tissue.HIC1 gene is located in chromosome 17p13.3,in which loss of heterozygote or super-methylation is frequently found in a variety of human cancers.As a new tumor marker,HIC1 has been confirmed down-regulated in a wide variety of solid cancers because of HIC1 promoter hypermethylation,and may be associated with tumor prognosis.As a tumor suppressor,HIC1 participates in the development of tumor process through various ways,and is involved in cell proliferation,tumour growth,and angiogenesis.Therefore,the abnormal hypermethylation or the loss of expression of HIC1 in tumor cells or abnormal function could be one of the important mechanisms of tumor development,and may become a new potential therapeutic targets for cancer.
3.THE EXPERIMENTAL STUDY OF STRESS FRACTURE OF THE METATARSAL BONES IN NORMAL CHINESE ADULTS
Yuanying ZHANG ; Hongshun MA ; Weiqin GUO
Chinese Journal of Sports Medicine 1982;0(01):-
The stress fracture is often resulted from forced march, heel-and-toe walking race, trudge over a longdistance etc. The stress fracture in metatarsal bone is very common. After analysis of bearing-force onmetatarsal bone, the feet are simplified as weight-bearing-cantilever beam structure, while the metatarsalbone as lever units which support the bending cantilever. 16 metatarsal bones were taken from freshcadavers of normal Chinese adults. TYPE 2H cantilever stress teeting machine was used for the experiment.This study analyzes the injury mechanism of stress fracture theoretically, the defines limit of stress fractureof the metatarsal bone, and makes biomechanical analysis for the fracture types. This experiment providesthe data and materials for prevention and diagnosis of stress fracture and the possibility of methods andpaths for stress fracture experiment of the biomaterials.
4.Meta-analysis on relationship between ApoB gene XbaI polymorphism and cerebral infarction in Chinese population
Shuo ZHANG ; Yang GUO ; Yan MA
Journal of Clinical Neurology 1997;0(06):-
Objective The relationship between XbaI polymorphism of ApoB gene and cerebral infarction(CI)among Chinese population was assessed by Meta-analysis.Methods All related case-control studies were collected from all publications,the relevant studies were identified after eliminating those poor-qualified studies.Meta-analysis was conducted for investigating heterogeneity among individual studies,and summarizing the effects across studies.Results The combined data statistics revealed the frequencies of the X-X+/X+X+ genotypes showed no statistically difference(Z=1.72,P=0.08).Through the subgroup analysis,it was obviously increase the risk of CI in Chinese northern population(OR=2.66,95%CI:1.67~4.24),but no statistically difference in Chinese southern population(OR=1.26,95%CI:0.90~1.77).Conclusions ApoB gene XbaI polymorphism may be significantly associated with susceptibility of CI in Chinese northern population,but not a definite risk for Chinese southern population.
5.Rapid Determination of Trace Formaldehyde in Drinking Water by Oscilloscopic Polarography
Zhidong MA ; Zhong GUO ; Wende ZHANG
Journal of Environment and Health 1993;0(03):-
Objective To study a rapid method for determination of trace formaldehyde in drinking water by oscilloscopic polarography.Methods In the base solution of0.01mol/L H 3 PO 4 ,the reaction product of formaldehyde and phenylhydrazine hydrochloride on the drop mercury electrode revealed a sensitive second order derivative polarographic wave at a pick electric potential-0.76V(VS?SCE).The optimum conditions and interference by other coexisting ions were analyzed.Results The de-tection limit,linear range,recovery rate,relative standard deviation(RSD)of the method were0.002mg /L,0.005-0.25mg /L,94.0%-103.0%,and0.05).Conclusion The method was simple,rapid,sensitive and highly specific.The analytical speed was about 50-60samples /h,which was suitable for the determination of trace formaldehyde in drinking water.
7.Study on Iron,Zinc,Copper,Manganese and Selenium Contents in Serum of Patients Suffering From Acute Myocardial Infarction and Using Thrombolysis Therapy
Xiaolin GUO ; Guozhen MA ; Meilan ZHANG
Journal of Chinese Physician 2002;0(S1):-
By using thrombolysis therapy,34 patients suffering from acute myocardial infarction were treated.And by comparing iron.zinc,copper,manganese and selenium contents in serum of 34 patients suffering from acute myocardial infarction with that of control group and the contents between before-treating and after-treating,following results are revealed:before treating,iron,zinc,copper contents in serum of the patients increased while manganese and selenium contents decreased,there is great difference between the contents of the patients and control group(P
8.Ancient literature on the heat control of umbilicus fumigation method and the modern clinical research.
Xiaoning ZHANG ; Xin GUO ; Baoluo YU ; Na ZHANG ; Yuxia MA
Chinese Acupuncture & Moxibustion 2016;36(1):71-73
In order to improve the clinical efficacy of the umbilicus fumigation method, the ancient literature with the heat control of umbilicus fumigation method involved is collected extensively and analyzed systematically, and the heat control, precautions and contraindications of this method are discussed. In association with the cases and the present clinical experience, the main factors to the heat control are introduced, such as preparation of doughnuts, filling quantity, size of moxa cone and numbers of moxa cones so that the clinical application of the umbilicus fumigation method can be promoted and enhanced.
Biomedical Research
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China
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Drugs, Chinese Herbal
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chemistry
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pharmacology
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Fumigation
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History, Ancient
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Hot Temperature
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Humans
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Medicine in Literature
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Medicine, Chinese Traditional
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history
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methods
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Umbilicus
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physiopathology
9.Investigation of self-efficacy and countermeasures for the nursing activities of nurses in operation room
Yueling ZHANG ; Jinrong GUO ; Hongfen ZHANG ; Hongxia MA
Chinese Journal of Practical Nursing 2012;28(19):1-3
Objective To investigate the self-efficacy for the nursing activities of nurses in the operation room and explore the ways of improving the self-efficacy of nursing activities of nurses in the operation room.Methods 160 nnrses in the operation rooms of four hospitals in Binzhou city were chosen as the observation group.160 non-operation room nurses in these four hospitals were chosen as the control group.The self-efficacy of nursing activities questionnaires were used to survey the self-efficacy of nurses.According to the analysis of survey results,measures to improve the self-efficacy of nursing activities were discussed.Results The self-efficacy scores for 160 operation room nurses were lower than those non-operation room nurses.Among 5 dimensions,nursing skill was with the lowest score in 160 nurses who had been investigated.The difference of self-efficacy scores of care activities for nurses in operation rooms of different hospitals was significant.Conclusions Nursing activity in the operation room has its own specialty.The self-efficacy of nursing activities was lower than non-operation room nurses generally,especially in nursing skills.Improving leadership and working environment of nurses,giving positive social support and re-education programs are the scientific ways to improve self-efficacy of nursing activities in the operation room.
10.Relevant factors of survival within 1 year of femoral head replacement in aged patients
Dangfeng ZHANG ; Wei MA ; Zhaohui GE ; Fei ZHANG ; Chihua GUO
Chinese Journal of Tissue Engineering Research 2015;(26):4127-4131
BACKGROUND:The age, complication, injury to operation time, and pain level are important factors that affect patients with postoperative mortality, but many scholars disagree. Factors affecting death in elderly patients after femoral head replacement stil need further study. OBJECTIVE:To observe factors related to the survival status of elderly patients within 1 year after receiving femoral head replacement. METHODS:A total of 96 elderly patients receiving femoral head replacement at Department of Orthopedics, the First Affiliated Hospital of Xi’an Jiaotong University from January 2011 to January 2014 were selected. On admission, patients’ age, sex, time from injury to operation, injury to admission time, pain classification, admission hemoglobin, serum albumin content of admission, admission lymphocyte count, and the amount of blood transfusion and preoperative complications were recorded. Fisher test was used to analyze the factors affecting survival status within 1 year after replacement in patients with femoral head replacement using one-way analysis of variance. Multivariate Cox test was utilized to perform multi-factor analysis. RESULTS AND CONCLUSION: The injury to hospital time was > 5 days. Pain classification was grades III and IV. The hemoglobin content was < 120 g/L on admission. The volume of blood transfusion was > 1 000 mL. Serum albumin content was < 35 g/L, which was associated with the increased mortality (P < 0.05). The mortality was significantly higher in patients with more than 86 years old than in patients with 70-85 years old (P < 0.05). The mortality of patients with the time from injury to operation > 7 days was significantly higher than patients with the time from injury to operation < 7 days (P < 0.05). The serum albumin content < 35 g/L and grades III and IV of ASA classification were factors related to patient’s death (P < 0.05). Results confirm that the risk factors for survival status within 1 year of femoral head replacement contain intraoperative volume of blood transfusion, admission to operation time, hemoglobin content, and grading of pain.