2.Combination of novel therapy for respiratory failure.
Chinese Journal of Pediatrics 2003;41(8):630-632
4.The role of focal adhesion kinase in the breast carcinoma 's adhesion and migration mediated by the coagulation factor Ⅶa/tissue factor
Yanli GUO ; Wenning WEI ; Shanjun SONG
Journal of Xi'an Jiaotong University(Medical Sciences) 2004;0(05):-
Objective To study the role of focal adhesion kinase in the breast carcinoma cell adhesion and migration mediated by coagulation factor Ⅶa combined with tissue factor to explore the mechanism of tissue factor promoting metastasis. Methods The count of adherent cells were detected by using colorimetric assay,cell migration was detected with modified Bodyen chamber,and the FAK and the tyrosine phosphorylation of FAK were detected by immunoprecipitation and Western blot.Results Factor Ⅶa combinaed with tissue factor induced the tyrosine phosphorylation of FAK,which took part in the cancer cell's migration.Conclusion FAK is an important message of the breast carcinoma's adhesion and migration mediated by TF.
5.Gene diversities of ESBLs in clinical isolates of Enterobacteriaceae
Qinglan GUO ; Shiduo SONG ; Wei QI
Chinese Journal of Infectious Diseases 2001;0(06):-
Objective To study the Genotype of local clinical isolates of Enterobacteriaceae producing extended spectrum ? lactamases. Methods K B test, conjugative transfer test, plasmid profile analysis, PCR, PCR RFLP, and DNA sequencing were used to detect the phenotype and genotype of 33 isolates of Enterobacteriaceae producing ESBLs. Results Eighty five percent of 33 isolates was resistant to cefotaxime which was obviously higher than that to ceftazidime. blaCTX M ESBLs was detected in 28 isolates by PCR, blaTEM DNA in 24 isolates, and blaSHV DNA in 9 isolates. Mutation of E104K was only identified in one TEM ? lactamase produced by EC98A7 by PCR RFLP. No substitution of G238S occurred in 9 SHV ? lactamases. DNA sequencing and DNA alignment showed the blaCTX M DNA fragments from 4 clinical isolates of EC98A7,EB56,CFR78 and, KP9941 belonged to CTX M type 1, with highest identity to blaCTX M 3 or blaCTX M 12 respectively. Conclusions CTX M ESBLs is carried in 85% isolates of Enterobacteriaceae producing ESBLs in this city. Most of the isolates carry 2 or more ? lactamases. E. coli EC98A7 produces two ESBLs, a TEM ESBL and a CTX M ESBL.
6.Pediatric Risk of Mortality Ⅲ Score and Pediatric Critical Illness Score
Journal of Applied Clinical Pediatrics 1992;0(06):-
The pediatric risk of mortality Ⅲ(PRISM Ⅲ) score and pediatric critical illness score(PCIS) are physiology-based scores for assessing the severity of illness and mortality risk in pediatric patients.The PRISM Ⅲscore was revised version of the PRISM and was first developed in 1996.It includes 17 physiologic variables subdivided into 26 ranges.It had been validated by numerous studies worldwide and is the most widely known and used at pediatrics intensive care unit(PICU).The PCIS was first developed in 1995 in China,which included 10 physiologic variables.It had been validated by numerous studies nationwide and was simple,effective and suitable to Chinese situations.The scoring systems also can be used for quality assessments,grading the severity of illness in clinical study,and(stu)-dies of ICU resource utilization and management.There were no such study for validating the PRISM Ⅲ at present,comparing the performance of the PRISM Ⅲ score and the PCIS in China.
8.Proposal for building a disaster-medicine rescue system in Hainan Province
Chuanzhu LV ; Jiahe LV ; Liping WANG ; Wei SONG ; Min GUO
Chinese Journal of Hospital Administration 2008;24(11):728-731
Based on the analysis of the status quo and development trends of disaster medicine system abroad along with a summary of the present conditions and inadequacies of the same system in China, this paper proposes to build such a system in Hainan Province. It studied, with reference to the specifics of Hainan Province, the characteristics of such a system in the province, involving such aspects as hospital setup, human resource development, construction of research centers, professional training,management of disease control centers, improvement of the hospital self-rescue system, reliable supply of drugs and medical devices, maintenance of disaster medicine information system, logistics support,improvement of assessment system, establishment of rescue-oriented culture, and psychology crisis intervention and promotions.
9.Effect of treatment with early blood purification combined with prednisone and cyclophosphamide for patients with acute paraquat poisoning.
Yong-song JI ; Kai-yang DU ; Wei-ping GUO
Chinese Journal of Industrial Hygiene and Occupational Diseases 2013;31(5):388-389
Acute Disease
;
Adolescent
;
Adult
;
Aged
;
Cyclophosphamide
;
administration & dosage
;
therapeutic use
;
Female
;
Hemoperfusion
;
Humans
;
Male
;
Methylprednisolone
;
administration & dosage
;
therapeutic use
;
Middle Aged
;
Paraquat
;
poisoning
;
Renal Dialysis
;
Retrospective Studies
;
Young Adult