2.Protocols designing of treating varicose veins of the lower extremity by combining surgery and sclerotherapy, report of 31 cases
Hao ZHANG ; Peng WANG ; Xingyou GUO
Chinese Journal of General Surgery 2016;31(4):277-280
Objective To evaluate combination of traditional surgery and sclerotherapy in treating varicose veins of the lower extremity.Method This protocol includes high ligation of the great saphenous vein (GSV),stripping or laser closing of GSV above knee,injection of sclerosing agent into GSV below knee;ligating the perforator veins;sclerosing agent injection for varicose vein in 31 cases of varicose vein of the lower extremitis,among them seven were recurrent cases from April 2015 to June 2015.The clinical classification was as follows:nine cases of C2,four cases of C3,seventeen cases of C4,and one case of C6.All the perforator veins were located before the operation by color ultrasound.Results The number of perforator veins varied significantly (P <0.01) among the inner and back side of calfs (4.16 ± 1.86),the lateral calfs (1.29 ± 1.10),and thighs (0.16 ± 0.45).Twenty-four patients received high ligation of GSV combined with stripping of above-knees.Two patients received high ligation of GSV combined with the laser closing of above-knees.Five cases were treated conservatively (in which four have stripped or closed and one was on normal condition).Below-knee GSV were treated by sclerosing foam in 27 cases,and four cases were untreated (in which three have closed and one was normal).All the thirty-one cases underwent mini-incision for ligating the perforators and having the varicose veins closed using the sclerosing foam.All patients' GSV with sclerotherapy have got sclerosed.There were no complications of deep vein thrombosis,pulmonary embolism,or visual disturbance.Conclusion This operation design ensures the effect and prevents the recurrence of varicose vein,as well as reduces surgical trauma.
3.Diagnosis value of vascular ultrasound examination in detection of carotid artery disease
Hongchun ZHANG ; Tao PENG ; Lei GUO
Chinese Journal of Primary Medicine and Pharmacy 2010;17(17):2324-2325,后插一
Objective To study the clinical value of vascular ultrasound examination in detection of carotid artery disease. Methods 53 cases of ischemic cerebrovascular disease who served as experimental group,tested 387 vessels; and used the same period 55 cases of healthy persons as control group, tested 394 blood vessels. Comparison of two blood flow parameters between groups with differences in plaque detection. Results The results of vascular ultrasound examination could detect the visual display and quantitative carotid artery lesions in the experimental group a significant thickening of carotid artery IMT,carotid artery plaque prevalence was significantly higher than control group (P <0.01). Conclusion Vascular ultrasound examination was an effective screening method to detect ischemic cerebrovascular disease.
4.Vagal effects on atrial fibrillation thresholds of pulmonary veins after autonomic denervation
Peng LIU ; Jihong GUO ; Haicheng ZHANG
Chinese Journal of Practical Internal Medicine 2006;0(20):-
Objective To investigate vagal effects on atrial fibrillation(AF)thresholds at different sites of pulmonary veins after autonomic denervation.Methods In 10 mongrel dogs,the cervical vagal trunks were isolated bilaterally and decentralized from Oct 2004 to May 2005.The ansae subclaviae were exposed bilaterally as they exited from the stellate ganglia,doubly ligated,and cut.Local rapid electrical stimulation(S1S1=80 ms,impulse duration 0.5 ms)was performed to right appendage(RAA)、left appendage(LAA)、left atrium(LA)and different sites of 4 pulmonary veins.AF threshold was determined at each site in the baseline state,during bilateral cervical vagal stimulation(VNS,12.5 Hz,impulse duration 0.5 ms,stimulation voltage 5~8 V)and during infusion of atropine.Results During VNS,a lower AF threshold was observed at all sites,especially at distal of 4 pulmonary veins(P0.05).Conclusion Vagal nerve not only contributes to the maintenance of AF originating from pulmonary veins,but also greatly promotes the initiation of AF.
5.Clinical significance of (18)F-FDG PET-CT in evaluation of the therapeutic efficacy of chemotherapy for lung cancer.
Peng JIA ; Wan-hua GUO ; Ying ZHANG
Chinese Journal of Oncology 2009;31(3):235-236
Adult
;
Aged
;
Antineoplastic Combined Chemotherapy Protocols
;
therapeutic use
;
Carcinoma, Non-Small-Cell Lung
;
diagnostic imaging
;
drug therapy
;
Female
;
Fluorodeoxyglucose F18
;
Humans
;
Lung Neoplasms
;
diagnostic imaging
;
drug therapy
;
Male
;
Middle Aged
;
Positron-Emission Tomography
;
Small Cell Lung Carcinoma
;
diagnostic imaging
;
drug therapy
;
Tomography, X-Ray Computed
6.Alzheimer's disease and sleep disorders
Rongyan ZHU ; Peng GUO ; Wei ZHANG
Chinese Journal of Geriatrics 2017;36(1):1-4
8.Treatment and correction for SPECT image fault
Yong GUO ; Jing PENG ; Kunfeng ZHANG ; Yang ZHANG ; Ying ZHOU
Chinese Medical Equipment Journal 2004;0(07):-
This paper analyzes the reason of spurious image and discusses how to control quality and correct image for the requirement of quality control.
9.Association of (CCTTT) n microsatellite polymorphism of iNOS gene with diabetic nephropathy in Chinese Hans
Zheng ZHANG ; Huimin PENG ; Suhua ZHANG ; Fengjin GUO ; Ning YAN
Chinese Journal of Endocrinology and Metabolism 2000;0(06):-
The frequency of inducible nitric oxide synthase (iNOS) gene (CCTTT) 14 allele was significantly lower in diabetic nephropathy group (0.044) than that in diabetics without nephropathy (0.170, P
10.Study of effect and mechanism of cyclooxygenase-2 on the prostatic hyperplasia in rats
Qian ZHANG ; Jing PENG ; Xianghua ZHANG ; Yinglu GUO ; Jie JIN
Chinese Journal of Urology 2001;0(07):-
Objective To investigate the effect and molecular mechanism of cyclooxygenase-2 (COX-2) on the benign prostatic hyperplasia (BPH) in rat model. Methods Thirty-six SD rats were randomly divided into 3 groups:normal control (group A,n=12),BPH model (group B,n=12) and BPH+selective COX-2 inhibitor celecoxib (group C,n=12). At the 5th week after treatment, the weight of the prostates was measured, and the morphological changes were examined under light microscope.Detection of ki-67 and TUNEL in prostatic epithelial and stromal cells was undertaken to assess the proliferation and apoptosis status.The protein and mRNA expression of COX-2,epidermal growth factor (EGF),basic fibroblast growth factor (bFGF) and transforming growth factor-?1 (TGF-?1) were analyzed by means of immunohistochemisty and RT-PCR. Results The prostate index [prostate wet weight (mg)/rat body weight (g)] of group B was significantly higher compared with those in groups A and C (1.88?0.17 vs 1.70?0.09 and 1.74?0.16,P0.05). Conclusions The increased expression of COX-2 may play an important role in the pathogenesis of BPH by modulating the expression of growth factors and affecting the proliferation and apoptosis of prostate cells.