Acupuncture Therapy ; Adult ; Alcoholism ; therapy ; Humans ; Male ; Medicine, Chinese Traditional ; Middle Aged ; Peripheral Nervous System Diseases ; therapy

Objective: To investigate the effects of supplementing multivitamins on the growth and development of children. Methods: A total of 24 000 children (6 8 years old) from Shanghai, Beijing and Guangzhou were divided into 2 groups. One group was given multivitamin tablets and another was without any treatment for 12 weeks. Each tablet contains VA 5 000 IU, VD 400 IU,VE 30 IU,VB 1 1.5 mg,VB 2 1.7 mg,niacin 20 mg,VB 6 2 mg,VB 12 6 ?g,folic acid 0.4 mg and VC 60 mg. Height, body weight, skinfold thickness, mid arm muscle circumference and serum VA, 25 OHD 3, Hb, IgA,IgG and IgM were measured before and after supplementing multivitamins.VB 1, VB 2 and VC were evaluated by four hours loading test. Results: It was found that vitamin deficiencies, especially that of VA, VB 2 and VB 1, existed in the children. After supplement, the net increase of height and weight was significantly higher than that of control group. Levels of serum VA, 25 OHD 3 and Hb in supplemented group were significantly increased and the urinary excretion of VB 1, VB 2 and VC was also significantly increased in supplemented group. Conclusion: The results indicate that the multivitamins is conductive to improvement of vitamin status and nutritional anemia, and to growth and development. It is necessary for children with routine diet to supplement multivitamins. [

Objective To study the association of sex, body mass index and insulin resistance with serum leptin in patients with type 2 diabetes. Methods one hundred and eight patients were divided into two groups according to BMI: diabetic obese group and diabetic normal BMI group.Their weight and height were measured. Fasting plasma glucose(FPG),fasting true insulin(FTI),postprandial true insulin(PTI),and fasting serum leptin(LEP) were also measured. ISI=1/(FPG?FTI) as insulin sensitivity index were used to analyse the relation between leptin and insulin resistance. Results ⑴The serum leptin,body mass index,FTI and PTI were significantly higher in diabetic obese group than diabetic normal BMI group. ISI was significantly lower in diabetic obese group than diabetic normal BMI group. ⑵Female serum leptin levels were significantly higher than male serum leptin levels in diabetic obese group and diabetic normal BMI group. ⑶Fasting leptin was correlated with sex. Leptin was positively corrected with body mass index,FTI and was negatively corrected with ISI. Serum leptin wasn't correlated with FPG. Conclusin Serum leptin level is associated with sex,BMI and insulin resistance in patients with type 2 diabetes.

This paper studies the differences of rational use of drugs policy between China and America,mainly focusing on the differences in the policy of clinical pharmacists,the research and development process of substitute for drugs,the guarantee system of medical treatment.In addition,it naturally analyzes the reasons for these kinds of differences from the view of culture and value.At last,it deeply summarizes the humanism positions and justice principles based on which the Rational Use of Drugs was drawn up from the angle of ethics.

OBJECTIVE: To optimize the therapeutic regimen for acute cerebral infarction for clinical reference. METHODS: Medical records of patients in who acute cerebral infarction occurred for the first time in a hospital during 2003～2006 were analyzed statistically in respect of drug use. RESULTS: In terms of DDDs, dehydrants, diuretics, platelet aggregation inhibitors, promoting cerebral circulation agents and supportive drugs took the lead in this hospital. The DDDs of drugs used for complications in descending order were antiinfectives, hypotensors, and drugs for heart diseases. CONCLUSION: The drugs used for inpatients with acute cerebral infarction varied in kinds; therefore, clinical choice of drugs and the rationality of drug use remain to be further studied.

Flavonoid Pilulae from Gegen were prepared by melting method. Using PEG 4000 and PEG 6000 as carrier. Serious of studies on the in yitro release kinetics were carried out.PEG4000 ; PEG6000 ratio had no effect on the release kinetics. PEG 4000: flavonoids ratio had an evident effect on the release properties of the pilulae, the higher the ratio,the faster the release rate. But when the PEG 4000, flavonoids ratio exceeded 10: 1, a reverse effect could be seen. Compared with "Gegen flavonoids" tablets, "Yufengingxin" tablets(release half time, T50= 94.79min), the pilulae gave a much fast release characteristic (T50 = 11. 56min).

Damaged articular cartilage has a limited intrinsic capacity to heal itself,especially in adults,It represents a clinical challenge.Novel gene therapy can introduce particular beneficial gene into the seeded sells and express growth factors or other therapy proteins at the repair site.Gene therapy focuses on selecting proper gene,target cells and the transferring systems. The tissue engineering cartilage with gene-modified seeding cells and transferring objective gene to target sells locally present new therapeutic regimens for repairing defects in articular cartilage.

Objective Statistics the distribution regularity of algae literature in biomedical periodicals written in Chinese. Methods The specialized articles on algae are distributed in 285 types of Chinese periodicals with total 914 articles after retrieving Chinese Biomedical Literature Database(from 1995 to March of 2004). According to Bradford' law and Bradford zone method, three zones are divided into an approximately equal quantity of articles. The zone division is based on the quantity of articles in the periodicals and a digressive sequence as well. Results There are 14 periodicals in the first zone with 308 articles published, which are 4.91% of the total periodicals and 33.7% of the total articles. It could provide the 1/3 information and it is the Core Journals. Conclusion The articles published in Chinese Journal of Marine Drugs are the most, which reaches 90 and occupies 9.8% of the total; therefore, it shall be given priority when alga articles are selected. The scientific comments on periodicals can direct researchers on algae to attain necessary information.

Cartilage lesions resulting from acute or chronic injury are one of the major factors leading to joint disease and disability ,and eventually osteoarthritis. It is well known that articular cartilage in adults has a limited ability for self-repair,and represent a clinical management challenge. Numerous methods have been devised to augment its natural healing response. The most appropriate treatment option for an individual patient should be based on the pathologic characteristics of the lesion and the patient's symptoms, age and expectations. This review presents the current articular cartilage management and the direction in future therapeutic regimens.