Objective:To compare the effect of intraoral and extraoral approach for the sugical treatment of mandibular cysts in the angle and ramus. Methods:Cysts in the mandibular angle and ramus were treated by intraoral approach in 57 cases and extraoral in 18 cases. The following data were collected: operation time, peroperative blood loss, postoperative infection, mouth opening, recurrence rate, injury of the submandibular branch of the facial nerve and sensory function of the inferior alveolar nerve. The data of the two groups were compared statistically. Results:Average operation time (min) of intraoral and extraoral appoarch was 84.65?5.16 and 122.78?10.84(P0.05). Conclusion:Intraoral approach is effective in the treatment of cyst in mandibular angle and ramus.

Objective To compare the diagnostic value of CT and NE for lesions of nasal cavity and paranasal sinus area.Methods 80 cases of nasal and paranasal sinus diseases which were examined by both CT and NE at same period and proved by pathology.were reviewed.Results Compare with results of pathology,the accucy rate of both CT and NE was identical in diagnosing sinusitis and tumours of paranasal sinus,NE was higher than CT in nasal and paranasal sinus polyp and nasal cavity tumour,turbinate hyperplasia CT was higher than NE in paranasal sinus cyst and anatomic variations.Conclusion Pathologic biopsy can be taken under NE guide to understand the shape,texture and colour of the illness focus CT can show the size,shape and anatomy relation between lesion and its neighbor tissue.The diagnosis may more perfectly through NE combined with CT.

Objective To study 64-slice CT perfusion features of metastatic tumors of liver and its clinical value.Methods 23 cases (40 lesions) with liver metastases underwent CT perfusion scanning.Hepatic arterial perfusion index(HPI) parameters including blood flow perfusion(BF),patlak blood capacity (pBV),vascular permeability (P,permeability),arterial liver perfusion(ALP),portal venous perfusion( PVP ) were analyzed in comparison with that of normal liver .Results (1)BF, pBV , P , ALP , PVP and HPI in normal liver tissue were (47.85?8.11) ml?100ml-1?min-1,41.25?6.32 (1000:1), 64.25?11.10 (0.5 ml?100ml-1?min-1),(24.55?2.96) ml?100ml-1?min-1, (105.24?16.42) ml?100ml-1?min-1,(20.18?3.81),respectively.(2)BF,pBV,P,ALP and PVP between the normal hepatic tissue and the centre of lesions were of statistically significance (P

[Summary] Postoperative cognitive dysfunction ( POCD) is a common central nervous system complication after anesthesia and surgery.The mechanisms of POCD are not clear yet.The article reviewed several potential mechanisms that have been reported. Further researches are needed to identify the pathophysiologic progress of POCD, which have great clinical and economic values.

Congresses as Topic ; Humans ; Otorhinolaryngologic Surgical Procedures

Objective:To observe therapeutic effect of continuous renal replacement therapy (CRRT ) on different types of cardiorenal syndrome (CRS) .Methods :According to patient′s conclition ,a total of 247 CRS patients were divided into type 1 group (n=47) ,type 2 group (n=51) ,type 3 group (n=55) ,type 4 group (n=49) and type 5 group (n=45) .All patients received CRRT ,echocardiography and plasma level of N terminal pro B type natriuretic peptide (NT‐proBNP) detect to evaluate cardiac function status ;the 24h urine volume and endogenous creatinine clearance rate (Ccr) were measured to assess renal function status before and after treatment . Results:Compared with before treatment ,on one week after CRRT ,LVEF ,urine volume and Ccr level significantly rose ,NT‐proBNP level significantly reduced ( P<0.05 or <0.01) .Compared with type 4 and 5 group ,there were significant rise in LVEF [ (48.98 ± 1.55)% ,(44.67 ± 1.48)% vs .(55.13 ± 4.27)% ,(53.73 ± 3.52)% ,(57.95 ± 2.89)% ] ,urine volume [ (1118.83 ± 168.09 ) ml , (1125.47 ± 177.28 ) ml vs . (1655.67 ± 198.37 ) ml , (1697.47 ± 171.27 ) ml , (1702.72 ± 179.28) ml] and Ccr level [ (40.11 ± 1.79) ,(41.11 ± 1.39) vs .(52.33 ± 2.49) ,(50.97 ± 2.11) , (51.32 ± 2.01 )] , and significant reduction in NT‐proBNP level [ (3738.19 ± 118.77 ) , (3378.38 ± 121.82 ) vs . (2137.51 ± 123.59) ,(2421.12 ± 121.22) ,(2139.81 ± 147.28)] in type 1 ,2 and 3 group ,P<0.05 all .Conclusion:CRRT is effective on different types of CRS ,but it′s best on type 1~3 than those of type 4~5 , which may be re‐lated to different pathological mechanisms of CRS different types .

Objective To determine whether the cyclooxygenase-2 (COX-2) selective inhibitor,{N-[2-(cyclohexyloxy)-4-nitrophenyl]-methane sulfonamide} (NS398),can inhibit proliferation of COX-2 negatively expressed human prostate cancer cell line PC-3 and induce its apoptosis in vitro. Methods The expression of COX-2 in cultured PC-3 cells was examined by RT-PCR and Western blot for mRNA and protein respectively.The proliferative inhibition of PC-3 cells by NS398 was observed by methyl thiazolyl tetrazolium (MTT) rapid photocolorimetric assay.PC-3 cells cultured in 100 ?mol/L NS398 medium for 24 h was marked with AnnexinV-FITC and PI for the cell apoptosis assay by flow cytometry. Results COX-2 was not expressed in PC-3 cell line at either mRNA or protein level.The inhibitory rate of NS398 on proliferation increased with the increasing concentration but was not time-dependent.Compared with the controls (10.563?2.582)%,PC-3 cells cultured in 100?mol/L NS398 medium for 24 h had significantly higher incidence (19.307?3.773)%] Objective To determine whether the cyclooxygenase-2 (COX-2) selective inhibitor,{N-[2-(cyclohexyloxy)-4-nitrophenyl]-methane sulfonamide} (NS398),can inhibit proliferation of COX-2 negatively expressed human prostate cancer cell line PC-3 and induce its apoptosis in vitro. Methods The expression of COX-2 in cultured PC-3 cells was examined by RT-PCR and Western blot for mRNA and protein respectively.The proliferative inhibition of PC-3 cells by NS398 was observed by methyl thiazolyl tetrazolium (MTT) rapid photocolorimetric assay.PC-3 cells cultured in 100 ?mol/L NS398 medium for 24 h was marked with AnnexinV-FITC and PI for the cell apoptosis assay by flow cytometry. Results COX-2 was not expressed in PC-3 cell line at either mRNA or protein level.The inhibitory rate of NS398 on proliferation increased with the increasing concentration but was not time-dependent.Compared with the controls (10.563?2.582)%,PC-3 cells cultured in 100?mol/L NS398 medium for 24 h had significantly higher incidence (19.307?3.773)%] of early apoptosis (P=0.01).Conclusions NS398 can inhibit proliferation of COX-2 negatively expressed human prostate cancer cell line PC-3 and induce its apoptosis in vitro,which suggests its COX-2 independent pathway.

Objective To compare the short-term follow-up cu ra tive effect of primary total hip replacement (THR) in treating fresh and old fem oral neck fractures. Methods Double follow-ups with an in terval of 13 months were performed in patients with femoral neck fractures under going THR in our department from January 1997 to October 1999. Results After a follow-up for 37-62 months (mean 44 months), we obtained f ull data of 47 patients [41-77 years old, (61.8?5.22) years old] with preoperative Harris score of 28.40?10.14 and postoperative score of 85.20?7. 91. The Harris score of patients with fresh femoral neck fractures (FFNF) incr eased from 21.60?8.73 preoperatively to 82.50?9.81 postoperatively〔at age of (63.50?5.53) years〕 and that of patients with old femoral neck fracture (O FNF) from 37.70?13.50 to 90.63?5.79, [at age of (58.90?7.81) years]. Of 47 patients, only one case had dislocation once within six weeks postoperative ly during function exercise and recovered after manual reduction. Another one wi th excellent function evaluation was given again internal fixation three years a fter THR because of femoral shaft fracture and obtained satisfactory recovery. N o complications were found in other patients. The mean Harris score in patients with OFNF was significantly higher than those with FFNF ( P

Objective To examined the relationship between the Fast Plasma Glucose(FPG) and the Postprandial Plasma Glucose(PPG) by analyzing 3 588 OGTT and IRT,and assessed the role of PPG in the diagnosis of type 2 diabetes.Methods Data of OGTT and IRT in 3 588 patients from 2000-Jan to 2007-June were collected and the distribution of the patients evaluated with cut-points of fasting plasma glucose by 5.6 mmol/L,6.1 mmol/L & 7.0 mmol/L and postprandial plasma glucose by 7.8 mmol/L and 11.1mmol/L were analyzed.T-test and corrected t-test of two independent samples have been done with SPSS 11.5.Results By WHO standard,3 097 T2DM were diagnosed.Of 2654 T2DM patients diagnosed by FPG≥7.0 mmol/L,54 patients showed 2 h PG0.05).202 cases were NGT(but hyperinsulinemia and/or delayed insulin secretion were found in 113 of them,55.94%).Other 289 cases were IFG and/or IGT.In the 291 cases diagnozed with 1 h PG≥11.1 mmol/L and 2 h PG

Objective To observe the expression of ? APP and SS in the hippocampus of the rat mode ls with the deficits of learning and memory function, and investigate its mechanism.Methods Using immunohistochemistry (IHC), we detected the expressions of ? amyloid precursorprotein(? APP) and somatostatin(SS) in the hippocampus of the rat brains,using HE staining method, we observed the shapes and structures of pyramidal cell layer neurons in hippocampus of the rats in the experimental group and the controls.Results The learning and memory functions were lower significantly in the experimental group than in the controls ( P