1.Intraoral approach for surgical treatment of mandibular cyst in the angle and ramus
Journal of Practical Stomatology 2000;0(06):-
Objective:To compare the effect of intraoral and extraoral approach for the sugical treatment of mandibular cysts in the angle and ramus. Methods:Cysts in the mandibular angle and ramus were treated by intraoral approach in 57 cases and extraoral in 18 cases. The following data were collected: operation time, peroperative blood loss, postoperative infection, mouth opening, recurrence rate, injury of the submandibular branch of the facial nerve and sensory function of the inferior alveolar nerve. The data of the two groups were compared statistically. Results:Average operation time (min) of intraoral and extraoral appoarch was 84.65?5.16 and 122.78?10.84(P0.05). Conclusion:Intraoral approach is effective in the treatment of cyst in mandibular angle and ramus.
2.Comparative Study of CT and Nasal Endoscope(NE) in Diagnosis of Lesions of Nasal Cavity and Paranasal Sinu
Ying GUO ; Dapeng SHI ; Guangke WANG ; Zhenling YANG ; Anqi GUO
Journal of Practical Radiology 2001;0(06):-
Objective To compare the diagnostic value of CT and NE for lesions of nasal cavity and paranasal sinus area.Methods 80 cases of nasal and paranasal sinus diseases which were examined by both CT and NE at same period and proved by pathology.were reviewed.Results Compare with results of pathology,the accucy rate of both CT and NE was identical in diagnosing sinusitis and tumours of paranasal sinus,NE was higher than CT in nasal and paranasal sinus polyp and nasal cavity tumour,turbinate hyperplasia CT was higher than NE in paranasal sinus cyst and anatomic variations.Conclusion Pathologic biopsy can be taken under NE guide to understand the shape,texture and colour of the illness focus CT can show the size,shape and anatomy relation between lesion and its neighbor tissue.The diagnosis may more perfectly through NE combined with CT.
3.Clinical Application of 64-slice CT Perfusion Imaging in Hepatic Metastases
Yuli WANG ; Shunlin GUO ; Jigang GUO ; Baozhi YANG
Journal of Practical Radiology 2001;0(08):-
Objective To study 64-slice CT perfusion features of metastatic tumors of liver and its clinical value.Methods 23 cases (40 lesions) with liver metastases underwent CT perfusion scanning.Hepatic arterial perfusion index(HPI) parameters including blood flow perfusion(BF),patlak blood capacity (pBV),vascular permeability (P,permeability),arterial liver perfusion(ALP),portal venous perfusion( PVP ) were analyzed in comparison with that of normal liver .Results (1)BF, pBV , P , ALP , PVP and HPI in normal liver tissue were (47.85?8.11) ml?100ml-1?min-1,41.25?6.32 (1000:1), 64.25?11.10 (0.5 ml?100ml-1?min-1),(24.55?2.96) ml?100ml-1?min-1, (105.24?16.42) ml?100ml-1?min-1,(20.18?3.81),respectively.(2)BF,pBV,P,ALP and PVP between the normal hepatic tissue and the centre of lesions were of statistically significance (P
4.APPLICATION OF COLLOIDAL GOLD-TECHNIQUE FOR LOCALIZATION OF CON A RECEPTORS IN HUMAN SPERM
Longshen WANG ; Rengyu GUO ; Shaoyi YANG ;
Acta Anatomica Sinica 1953;0(01):-
Intact and gossypol-treated spermatozoa from healthy man were labeled withCon A-HRP-G two-step method.Comparative observations of these sperms were doneunder LM,TEM and SEM.Results show that there are gold particles on spermsurface membrane.Their distribution is more dens on plasma membrane of spermhead and middle piece.On the intracellular membrane structures of sperm which plasmamembrane was damaged by gossypol the gold particles also can be seen,especially onthe membranes of acrosome and mitochondria.It was proved that Con A receptorsare present not only on plasma membrane of sperm,but also on the membrane ofacrosome and mitochondrion.The significance of Con A receptors on sperm struc-tures,advantages of Con A-HRP-G two-step labeled method and comparativeobservations under LM,TEM and SEM were discussed.
5.Research Progress of Pathogenesis Mechanisms of Postoperative Cognitive Dysfunctions
Yang ZHOU ; Jun WANG ; Xiangyang GUO
Chinese Journal of Minimally Invasive Surgery 2015;(7):658-662
[Summary] Postoperative cognitive dysfunction ( POCD) is a common central nervous system complication after anesthesia and surgery.The mechanisms of POCD are not clear yet.The article reviewed several potential mechanisms that have been reported. Further researches are needed to identify the pathophysiologic progress of POCD, which have great clinical and economic values.
6.Absorption and transport of 6 coumarins isolated from the roots of Angelica pubescens f. biserrata in human Caco-2 cell monolayer model.
Xiuwei YANG ; Qingmei GUO ; Ying WANG
Journal of Integrative Medicine 2008;6(4):392-8
To study the absorption and transepithelial transport of six coumarins (umbelliferone, osthole, columbianadin, columbianetin acetate, angelol-A and angelol-B, isolated from the roots of Angelica pubescens f. biserrata) in the human Caco-2 cell monolayer model.
7.New drug delivery systems and the function of camptothecin
Jing DONG ; Shenglei GUO ; Yang WANG
Chinese Journal of Tissue Engineering Research 2007;0(23):-
Camptothecin is known to possess a broad spectrum of anticancer activities, however due to its high toxicity and low solubility in water, camptothecin is severely limited in clinic. To optimize the effects of camptothecin in the treatment of malignancies, besides the structural modification and reconstruction of camptothecin, the establishment of new drug delivery systems becomes a hot topic in the camptothecin research. This paper aims to summarize the advanced progress in the delivery system and function of camptothecin at recent years. The advances in improving the poor solubility, lactone ring instability, controlled release systems and targeting delivery systems of camptothecin are also reviewed. As the related methods and technologies are improved and developed, camptothecin will be a group of prospective anticancer drugs.
8.Analysis of the Working Principle and Maintenance of Evita 4 HPSV Valves
Yueqi YANG ; Ying WANG ; Dan GUO
Chinese Medical Equipment Journal 2003;0(12):-
By analyzing the structure and the working principle of Evita 4 HPS valve (HPSV=high-pressure servo-valve) in the mixer unit, and introducing detailed status of troubleshooting to give the solvents. The repairing examples and some effective ways about maintenance of the HPSV are provided at last.
9.Proliferation of scar tissues following fresh versus preserved amniotic membrane transplantation with trabeculectomy
Jing GUO ; Hongwei WANG ; Xuefang YANG
Chinese Journal of Tissue Engineering Research 2010;14(18):3323-3326
BACKGROUND: Fresh amniotic membrane has been extensively used in treating ocular surface disease, which can inhibit fibrous tissue proliferation, inhibit neovascularization, and relieve inflammation. However, its application in treating glaucoma is rarely reported.OBJECTIVE: To explore the antiproliferative effect of fresh amniotic membrane on postoperative scar and compared with preserved amniotic membrane.METHODS: A total of 36 New Zealand white rabbits were randomly divided into 3 groups. Fresh amniotic membrane and preserved amniotic membrane combined with trabeculectomy separately underwent fresh amniotic membrane and preserved amniotic membrane transplantation. The control group was subjected to trabeculectomy alone. After 1, 2, 3, and 4 weeks, the morphology and function of filtering bleb were checked, and the platelet-derived growth factor (PDGF) of surrounding tissue was determined by immunohistochemical method.RESULTS AND CONCLUSION: Fresh amniotic membrane and preserved amniotic membrane groups displayed bulged filtering bleb with good filtering function. Pathological observation showed that fibroblasts of the filtration pathway had less, but more sparse scar tissues than control group, but inflammatory infiltration was observed in all groups. The cavity of different sizes and shapes were detected in filtration pathway of control group, which was replaced by fibrous tissue hyperplasia, with a large number of fibroblasts. Immunohistochemical results showed that the expression of PDGF was significantly less in fresh amniotic membrane and preserved amniotic membrane groups compared with the control group, and the PDGF expression was less in fresh amniotic membrane group than the preserved amniotic membrane group. Fresh and preserved amniotic membrane can improve the filtering bleb function, reduce scar formation, and maintain the patency of filtering pathway. Moreover, the effects of fresh amniotic membrane is better than preserved amniotic membrane.
10.Short-term follow-up effect of total hip replacement in fresh and old femoral neck fractures of middle-aged and old patients
Liu YANG ; Lin GUO ; Wenliang WANG
Chinese Journal of Trauma 2003;0(11):-
Objective To compare the short-term follow-up cu ra tive effect of primary total hip replacement (THR) in treating fresh and old fem oral neck fractures. Methods Double follow-ups with an in terval of 13 months were performed in patients with femoral neck fractures under going THR in our department from January 1997 to October 1999. Results After a follow-up for 37-62 months (mean 44 months), we obtained f ull data of 47 patients [41-77 years old, (61.8?5.22) years old] with preoperative Harris score of 28.40?10.14 and postoperative score of 85.20?7. 91. The Harris score of patients with fresh femoral neck fractures (FFNF) incr eased from 21.60?8.73 preoperatively to 82.50?9.81 postoperatively〔at age of (63.50?5.53) years〕 and that of patients with old femoral neck fracture (O FNF) from 37.70?13.50 to 90.63?5.79, [at age of (58.90?7.81) years]. Of 47 patients, only one case had dislocation once within six weeks postoperative ly during function exercise and recovered after manual reduction. Another one wi th excellent function evaluation was given again internal fixation three years a fter THR because of femoral shaft fracture and obtained satisfactory recovery. N o complications were found in other patients. The mean Harris score in patients with OFNF was significantly higher than those with FFNF ( P