3.Correlation of a disintegrin and metalloprotease 12 level in maternal serum during the first trimester with pregnancy outcome
Hong QI ; Xuming BIAN ; Yulin JIANG ; Shanying LIU ; Qi GUO
Chinese Journal of Obstetrics and Gynecology 2009;44(6):401-404
05). Conclusion The maternal serum level of ADAM 12 in the first-trimester is a potential marker for aneupolyhaploid screening and early fetal loss prediction, and is suggested to be tested at 9-12 gestational weeks as part of prenatal screening.
4.A Jarisch-Herxheimer reaction misdiagnosed as pneumonia after an operation for laryngeal papillary lymphoma.
Qing-jun LIU ; Guo-qi LIU ; Shi-you WANG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2011;46(4):341-342
Diagnostic Errors
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Humans
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Inflammation
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diagnosis
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etiology
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Laryngeal Neoplasms
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surgery
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Male
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Middle Aged
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Papilloma
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surgery
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Pneumonia
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diagnosis
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Postoperative Complications
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diagnosis
5.Virological surveillance and variability of influenza viruses in Hebei,2005~2006
Yanfang LIU ; Shunxiang QI ; Ruiling GUO ; Lanfen LIU ; Guangyue HAN
Chinese Journal of Disease Control & Prevention 2008;0(04):-
N)compared with B/HongKong/330/2001.Conclusions H1,H3 and B virus were circulated in Hebei from 2005 to 2006.Recent viruses were changing in genetic characteristics,while influenza B viruses varied more obviously.
6.Clinical effect study of Puji-Xuanfei-Xiaodu decoction on acute bronchitis of exterior cold and interior heat
Lai GUO ; Wensheng QI ; Xiujie YANG ; Ping LIU
International Journal of Traditional Chinese Medicine 2015;(4):324-326
Objective To study the relieving cough effect ofPuji-Xuanfei-Xiaodu decoction on acute bronchitis.Methods 87 patients with acute bronchitis of exterior cold and interior heat were randomly divided into two groups(44 cases in a therapy group and 43 cases in a control group).Puji-Xuanfei-Xiaodu decoction was given to the patients in the therapy group and acute bronchitis syrup was given to the control group, to observe the influence on symptoms of cough, sputum, fever and headache. The course of treatment was 7 days. Results On the reliving cough aspect, 28 cases (63.6%) showed cure effect and 13 cases (29.5%) effctive, the total effective rate was 93.2% in therapy group with 44 cases; while in control group (43 cases), 15 cases (43.9%) showed cure effect and 23 cases (53.5%) effctive, the total effective rate was 88.4%. The symptoms of cough, phlegm, fever, headache and aversion to wind were significantly decreased in two groups. In therapy group, the numbers of cure effect, remarkable effect and efficacy were 22 (50%) ,11(25%) and 8 (18.2%) cases respectively, the total effective rate was 93.19% while the numbers of cure effect, remarkable effect and efficacy were 14 (32.6%) ,8(18.6%) and 12 (27.9%) cases respectively, the total effective rate was 79.07% in control group. The total effective ratio of two groups had significant difference (P>0.05).ConclusionsPuji-Xuanfei-Xiaodu decoction is effective in relieving cough.
7.Risk factors for breast cancer-related upper extremity lymphedema:a meta-analysis
Yuhuan XIE ; Qi GUO ; Fenghua LIU ; Yaqun ZHU ; Ye TIAN
Chinese Journal of Radiation Oncology 2014;23(2):93-97
Objective To systematically evaluate the risk factors for upper extremity lymphedema after breast cancer treatment and the strength of their associations.Methods PubMed,Ovid,EMbase,and the Cochrane Library were searched to identify clinical trials published up to December 2012.The quality of included studies was assessed by the Newcastle-Ottawa Scale;data analysis was performed by Stata 10.0 and RevMan 5.2;the strength of associations between risk factors and breast cancer-related upper extremity lymphedema was described as odds ratio (OR) and 95% confidence intervals (CI).Results Twenty-two studies involving 10106 patients were included in the meta-analysis.The risk factors for upper extremity lymphedema after breast cancer treatment mainly included axillary lymph node dissection (OR =2.72,95% CI=1.06-6.99,P=0.038),hypertension (OR=1.84,95% CI=1.38-2.44,P=0.000),body mass index (OR =1.68,95% CI=1.22-2.32,P =0.001),and radiotherapy (OR =1.65,95% CI =1.20-2.25,P =0.002),while no significant associations were found for such factors as chemotherapy,age,number of positive lymph nodes,and number of dissected lymph nodes.Conclusions The incidence of upper extremity lymphedema is high among patients with breast cancer after treatment,and axillary lymph node dissection,hypertension,body mass index,and radiotherapy are the main risk factors for lymphedema after breast cancer treatment.
8.Expression and signiifcance of PLTP and MIF in mice with bronchopulmonary dysplasia
Guifang LI ; Baohai SHI ; Guo YAO ; Junli LIU ; Chunhua QI
Journal of Clinical Pediatrics 2013;(9):876-879
Objective To study the expression and signiifcance of phospholipid transfer protein (PLTP) and macrophage migration inhibitory factor (MIF) in mice with bronchopulmonary dysplasia (BPD). Methods Ninety-six 4-day-old mice were randomly divided into oxygen group and air group. Mice in oxygen group were exposed to a FiO2 of 65%, and mice in air group were exposed to air. On day 7, 14, 21 and 28, blood and lung tissue samples from 12 randomly selected mice in each group were obtained. The serum levels of MIF and PLTP were measured by ELISA assay. The morphological changes of lung tissue were ob-served with HE staining. Results The mice in oxygen group showed thickened lung parenchyma and obvious pulmonary ifbrosis. The radioactive alveolar count was signiifcantly lower in oxygen group than that in air group (P<0.01). PLTP level in air group was increased gradually from day 7 to day 21, and began to decrease on day 28. PLTP level in oxygen group was increased from day 7 to day 14, and decreased on day 21 and day 28. MIF level in air group did not change during the experiment. MIF level in oxygen group was signiifcantly increased from day 7 to day 21, and began to decrease on day 28. Conclusions MIF and PLTP may be good biomarkers for the diagnosis of BPD.
9.Chemical constituents of Osmanthus fragrans fruits.
Wei YIN ; Jin-Qi LIU ; Guo-Sheng ZHANG
China Journal of Chinese Materia Medica 2013;38(24):4329-4334
By Silica gel, Sephadex LH-20 and other materials for isolation and purification and by physicochemical methods and spectral analysis for structural identification, 23 compounds were isolated and identified from ethyl acetate portion of alcohol extract solution of Osmanthus fragrans fruits. Their structures were identified as nicotinamide (1), D-allitol (2), 5-hydroxymethyl-2-furancarboxaldehyde (3), acetyloleanolic acid (4), benzoic acid (5), ergosta-7,22-dien-3-one (6), beta-sitosterol (7), borreriagenin (8), cerevistero (9), c-veratroylglycol (10), methyl-2-O-beta-glucopyranosylbenzoate (11), 3', 7-dihydroxy-4'-methoxyisoflavon (12), umbelliferone (13), caffeic acid methyl ester (14), oleanolic acid (15), (-) -chicanine (16), dillapiol (17), 3beta,5alpha, 9alpha-trihydroxyergosta-7-22-dien-6-one (18), 2alpha-hydroxy-oleanolic acid (19), betulinic acid (20), betulin (21), 3, 3'-bisdemethylpinoresinol (22), and lupeol (23). All compounds were isolated from the osmanthus fruit for the first time. Except for compounds 4, 7, 15, 19, 23, the rest ones were isolated from the this plant for the first time.
Drugs, Chinese Herbal
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chemistry
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Fruit
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chemistry
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Oleaceae
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chemistry
10.Clinical efficacy of benadryl cream and metronidazle cream in treatment of topical corticosteroid dependent dermatitis
Yuqing QI ; Guizhi ZHANG ; Guanglian GUO ; Hong JIANG ; Quanzhong LIU
Chinese Journal of Medical Aesthetics and Cosmetology 2009;15(4):220-222
Objective To assess the clinical efficacy and safety of 1% benadryl and 3 % metronidazle cream in the treatment of topical corticosteroid dependent dermatitis. Methods The study was conducted in a single-blind way. The 86 patients were divided into 3 groups: 1% benadryl and 3 %metronidazle cream (group A), loratadine (group B) and gluco-corticoids (group C). All preparations were applied twice daily for 8 weeks. Study visits took place at baseline and weeks 2, 4 and 8. Results The clinical response rate in the groups A, B and C was 86.20%, 73.33%, and 66.67%, respectively; the clinical response rate in group A was significantly higher than that in groups B and C (P<0.05). Conclusions 1% benadryl and 3 % metronidazle cream are effective and safe in the treatment of topical torticosteroid dependent dermatitis.