1.Performance verification of Sysmex XTˉ2000i hematology analyzer
Ping YANG ; Jinglan GUO ; Mei YANG
International Journal of Laboratory Medicine 2014;(24):3413-3414,3416
Objective To perform the performance verification of the Sysmex XT-2000i hematology analyzer.Methods Accord-ing to requirements of NCCLS EP5-A2,EP15-A2,EP6-A2,EP9-A2 documents,the accuracy,precision and linearity of the Symex XT-2000i hematology were evaluated and the detection results were compared with those detected by the Sysmex XE-2100i which participated in the external quality assessment(EQA)of Ministry of Public Health for long time.Results The accuracy,precision, linearity and contamination rate all are within the permissible range.Conclusion The performance of Sysmex XT-2000i is good,the determination results are reliable.As a perfect hematology analyzer,it can satisfy the hematological analysis of hospital clinical la-boratory.
2.Influence of Colon Hydrotherapy on Premature Infant with Jaundice
min, YANG ; ping, ZHANG ; guo-fei, LIN
Journal of Applied Clinical Pediatrics 1986;0(02):-
Objective To study the influence of colon hydrotherapy on premature infants with jaundice.Methods Based on intravenously infusing yinzhihuang and albumin and enzyme inducer,the warmed normal saline was poured into colon by 10 mL/kg per 8 hours in 40 preterm infants,and compared with 44 cases of control group.Serum bilirubin of all patients were measured at 24,72,120,168,216 hours,respectively.The days of meconiumbeing eliminated completely were recorded.Results The bilirubinemia level in trial group were lower in trial group than that in control group at every time and the rate of hyperbilirubinemia of the test group was lower(?~2=4.073 P
3.Preliminary Study on Personality Characteristics of Abused Children
Shi-chang, YANG ; Ya-lin, ZHANG ; Yu-ping, CAO ; Guo-ping, HUANG ; Guo-yi, GUO
Journal of Applied Clinical Pediatrics 2005;20(7):716-718
Objective To explore the personality characteristics of abused children in order to reduce the incidence of child abuse.Methods Two hundred and ninty five middle school students were investigated with general questionnaire and Eysenck Personality Questionnaire of children. Eighty six students experiencing child abuse (CA) last year as study group and one hundred and ninety six non-abuse children as controls (NCA) were analyzed by means of Eysenck Personality Questionnaire of children.Results The score of neuroticism in CA group was significantly higher than that in the control group (55.62±10.60/52.65±10.98,t=-2.114 P=0.035). The score of lie in CA group was significantly lower than that in control group (42.21±9.87/46.04±9.20,t=3.184 P=0.002). On the impact of different sex, the psychoticism score of male was significantly higher than that in the control group(52.37±11.49/48.04±9.97,t=-2.227 P=0.028), and the lie score was significantly lower than that in control group(41.03±9.18/46.18±8.79,t=3.125 P=0.002).The scores of those in the female were not significant.Conclusions There is a close association between the unstable emotion and child abuse in children, so training emotional self-control and emotional expression of children might be a intervention strategy in the future. In addition, the frequency of lie in children is probably one of factors that determine whether children are abused or not.
4.Analysis and design of signaling transfer mechanism based on third-party certification: quality prestige index of traditional Chinese medicine enterprises.
Guang YANG ; Nuo WANG ; Lan-Ping GUO ; Lu-Qi HUANG
China Journal of Chinese Materia Medica 2014;39(5):925-928
Traditional Chinese medicine market is a typical market with information asymmetry, which may lead to "lemons" problem. Third-Party Certification is efficient path to solve the problem of information asymmetry. For this reason geo-authentic and commodity classes certification seems to be very important. But as we know, information asymmetry happen in the stages of traditional Chinese patent medicines market. So a signaling transfer mechanism, which can deliver the quality signal, is badly needed in TCM market. This paper analysis and design of signaling transfer mechanism based on Third-Party Certification, which called quality prestige index of TCM enterprises (QPITCM). QPITCM can display quality information as a signal run through the TCM market.
Certification
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Drugs, Chinese Herbal
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economics
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standards
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Medicine, Chinese Traditional
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economics
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standards
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Quality Control
5.Clinical Usage and Analysis of Nutrition Drugs in 34 Hospitals from Shanghai during 2011-2013
Jianping ZHANG ; Quanjun YANG ; Liqiong ZONG ; Ping ZHANG ; Cheng GUO
China Pharmacy 2015;(29):4051-4054
OBJECTIVE:To provide reference and evidence for rational use of clinical nutrition. METHODS:The types of en-teral and parenteral nutrition and the cost of prescription were analyzed statistically in 17 third grade class A general hospitals,3 third grade class A special hospitals and 14 secondary general hospitals from Shanghai area during 2011 to 2013. RESULTS:Nutri-tion preparations were mainly used by hospitalized patients. Total cost of nutrition preparations in outpatient and emergency depart-ment respectively occupied 8.14%,8.77% and 8.89% of total cost of nutrition preparations in the hospital during 2011-2013. The parenteral nutrition was the main form of nutritional support. There were only three kinds of enteral nutrition in top ten nutrition preparations in the list of prescription cost. Although seven out of ten kinds of nutrition preparations were given enterally which was the main mode for outpatients and emergency patients,the cost of prescriptions of parenteral nutrition increased faster compared to enteral nutrition,especially alanyl-glutamine. CONCLUSIONS:Parenteral nutrition is the main mode of nutrition support,especial-ly for inpatients;great attention should be paid to the increase of the cost of prescriptions about parenteral nutrition in outpatients and emergency patients.
6.A clinical analysis of intensive gastrointestinal lavage method for treatment of 100 severe cases with stress ulcer bleeding in neurosurgery department
Guo-Ping YANG ; Qiang MIN ; Jun-Wu WEI ;
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care 2006;0(05):-
Objective To discuss the intensive gastric cavitary lavage method in treatment of stress ulcer bleeding(SUB).Methods The therapeutic effects of 100 patients with severe SUB in intensive care unit (ICU)from July 2005 to February 2008 treated with intensive gastric cavity lavage method were observed and analyzed.Results In these 100 cases,the bleeding was stopped successfully in 97 cases,the therapeutic effective rate being 97%;there were 17 cases died of complicated pulmonary infection(17%)and 3 cases of bleeding(3%),the total fatality rate being 20%.All the other cases were cured.Conclusion Intensive gastrointestinal lavage therapy is an effective method as acid inhibitor for treatment of SUB,but it can decrease the inhabitant flora in the stomach to pass through gastric-pulmonary route,thus the incidence of pulmonary infection was reduced.
7.The effect of autologous stem cell transplantation in multiple myeloma
Li-Ping YANG ; Yi-Xiao ZHANG ; Pei-Jing GUO ;
Cancer Research and Clinic 2006;0(11):-
There are many progresses in the therapy of MM with ASCT. ASCT improves the ratio of CR,EFS and OS,compared with conventional chemotherapy.Myeloma patients with renal failure or old age also can be candidate for ASCT.Tandem autologous transplantation improves the ratio of CR. Its impact to long-term EFS and OS still need to be judged.To improve conditional project,to choose suitable time,and- toselect consolidation schedule can boost therapeutic effect.
8.Clinical effect study of Puji-Xuanfei-Xiaodu decoction on acute bronchitis of exterior cold and interior heat
Lai GUO ; Wensheng QI ; Xiujie YANG ; Ping LIU
International Journal of Traditional Chinese Medicine 2015;(4):324-326
Objective To study the relieving cough effect ofPuji-Xuanfei-Xiaodu decoction on acute bronchitis.Methods 87 patients with acute bronchitis of exterior cold and interior heat were randomly divided into two groups(44 cases in a therapy group and 43 cases in a control group).Puji-Xuanfei-Xiaodu decoction was given to the patients in the therapy group and acute bronchitis syrup was given to the control group, to observe the influence on symptoms of cough, sputum, fever and headache. The course of treatment was 7 days. Results On the reliving cough aspect, 28 cases (63.6%) showed cure effect and 13 cases (29.5%) effctive, the total effective rate was 93.2% in therapy group with 44 cases; while in control group (43 cases), 15 cases (43.9%) showed cure effect and 23 cases (53.5%) effctive, the total effective rate was 88.4%. The symptoms of cough, phlegm, fever, headache and aversion to wind were significantly decreased in two groups. In therapy group, the numbers of cure effect, remarkable effect and efficacy were 22 (50%) ,11(25%) and 8 (18.2%) cases respectively, the total effective rate was 93.19% while the numbers of cure effect, remarkable effect and efficacy were 14 (32.6%) ,8(18.6%) and 12 (27.9%) cases respectively, the total effective rate was 79.07% in control group. The total effective ratio of two groups had significant difference (P>0.05).ConclusionsPuji-Xuanfei-Xiaodu decoction is effective in relieving cough.
9.Effect of Intravenous Injection of Dezocine on the Incidence of Adverse Reactions during the Operation of Cesarean Delivery
Ping LIU ; Fan YANG ; Hong HUANG ; Xuejun GUO
Journal of Kunming Medical University 2016;37(7):62-65
Objective To observe the effect of Dezocine in preventing the adverse reactions during the operation of cesarean delivery.Methods We selected 60 pregnant women in the ASA level Ⅰ who were going to undergo the operation of cesarean delivery.Then we divided them into two groups in random:group A (studying group) and group B (control group),each group had 30 patients.After the fetus were delivered,the patients in group A were given intravenous injection of 1mg of dezocine,and the patients in group B were only given 1 ml saline.Then we observe the heart rate (HR),systolic blood pressure (SBP) and the degree of blood oxygen saturation (SpO2) in seven time points,and analyzed the incidence of contraction pains,chills,nausea and vomiting during the operation in both groups.The time points were when patients entered the operation room (T0),the level of anesthesia was established (T1),5 minutes after fetus were delivered (T2),10 minutes after fetus were delivered (T3),15 minutes after fetus were delivered (T4),30 minutes after fetus were delivered (T5) and the end of operation (T6).Results Compared with group A,the SBP at T2,T3 and T4 were obviously higher than those in group B (P<0.05).And the HR increased at T2 to T6 in control group (P<0.05) as compared with group A.The incidence of contraction pains were milder in group A than group B (P<0.05).In group A,the incidence of chills was13.3%,and in group B,the rate was 30%.Conclusion Dezocine can prevent the adverse reactions during the operation of cesarean delivery.
10.Rosuvastatin inhibits homocysteine-induced smooth muscle cell phenotype transformation and its signal pathway
Bo YANG ; Ping LI ; Liping MENG ; Hangyuan GUO
Journal of Xi'an Jiaotong University(Medical Sciences) 2016;37(4):506-512
ABSTRACT:Objective To verify whether rosuvastatin can inhibit homocysteine (Hcy)‐induced rat aortic vascular smooth muscle cell (VSMC ) phenotype transformation and its potential mechanism .Methods The primary culture and identification of rat VSMCs were conducted , using VSMCs in passage4‐7 for the following experiments .The VSMCs were divided into 4 groups:control group ,Hcy (100μmol/L) group ,Hcy+ rosuvastatin group ,and Hcy+ rapamycin group .MTT was used to investigate the proliferation of VSMCs .Transwell chambers and wound healing were employed to test the migration ability of VSMCs . ICC was used to detect the VSMCs'morphology .Western blotting was used to investigate the expressions of SM‐actin ,SM‐MHC ,calponin ,OPN ,and p‐P70S6K1 in VSMCs of each group .Results Compared with those in control group , the proliferation and migration ability of VSMCs were significantly increased in Hcy modulation group (P< 0 .01) .The expressions of SM‐MCH and calponin increased but those of OPN and p‐P70S6K1 decreased in Hcy group compared with control group (P<0 .01) .The expression of SM‐actin did not significantly differ between the groups .Compared with those in Hcy modulation group , the proliferation and migration ability of VSMCs were significantly decreased in rosuvastatin and rapamycin groups ( P<0 .01) .The expressions of SM‐MCH and calponin increased while OPN and p‐P70S6K1 expressions decreased in rosuvastatin and rapamycin groups compared with Hcy group ( P< 0 .01 ) . Conclusion Hcy can induce the dedifferentiation of VSMCs ,and rosuvastatin can inhibit this effect of Hcy .Its potential mechanism may be realized via the mTOR/P70S6K1 signal pathway .