Objective To study the influence of cognitive behavioral intervention on the quality of marriage and family function in patients with depression. Methods 146 hospitalized patients with depression were divided into study group and control group according to the set sequence. The study group were given cognitive behavioral intervention and the control group were given routine nursing.All patients were assessed by Hamilton depression scale (HAMD), Hamilton anxiety scale (HAMA), family functioning (FAD), marriage quality questionnaire (ENRICH) to evaluate the depression and family function. Results The difference in ENRICH total score, marital satisfaction, conflict resolution, children and marriage, leisure activities and the relationship with family and friends,FAD total score, problem solving, emotional response was statistically significant between before and after the intervention of the study group ( <0.05) . In the 6th weeks, the difference in ENRICH total score, marital satisfaction, conflict resolution methods, children and marriage,leisure activities and the relationship with family and friends, FAD total score, problem solving,emotional response was statistically significant between the two groups ( <0.05);The difference in HAMD,HAMA score was statistically significant between the 0th and 6 th weeks of the two groups ( <0.05) . There was a negative correlation between HAMA and conflict resolution factor (=-0.48, <0.05) . There was a positive correlation between FAD and the HAMD total score (=0.43,<0.05) . There was a negative correlation between ENRICH and HAMD total scores (r=-0.46, <0.05) .Conclusion The cognitive behavioral intervention can improve the family function and the quality of marriage in patients with depression.

Objective To explore the effect of cognitive behavior intervention on the defense style of patients with depression. Methods One hundred and forty-six patients with depression in hospitalized were divided into study group and control group according to the set sequence. The study group and the control group were given cognitive behavioral intervention and routine nursing, respectively. All patients were assessed by Hamilton depression scale (HAMD), Hamilton anxiety scale (HAMA), Simplified Coping Style Questionnaire (SCSQ), and Defense Style Questionnaire (DSQ) . Results The differences of conceal type and positive coping factor were significantly before and after intervention in the study group ( < 0.05) . In the 6th week, the differences of conceal type and positive coping factor were significantly between the two groups ( < 0.05) . The differences of HAMD and HAMA scores were significantly between the 0 th and 6 th weeks of the two groups ( <0.05) . There was negatively correlated between HAMD and positive coping factor ( <0.05) . There were positively correlated between HAMD and the cover up defense mode ( <0.05),HAMA and the cover up defense mode ( <0.05) . Conclusion The cognitive behavior intervention could improve the depression and anxiety symptoms and defense style in patients with depression.

Disasters ; Emergency Medical Services ; Humans ; Wounds and Injuries ; therapy

Background and purpose: Langerhans cell histiocytosis (LCH) is a rare complex reticulocndotheliai disease that often invades the head and neck. There in no consensus of treatment. Radiation is one of the treatment options for the localized lesions. Our aim in the study was to analyze the radiotherapeutic efficacy for LCH in the head and neck region. Methods: 8 patients with eosinophilic granuloma (EG) and 1 case with Hand-Schuller-Christian disease (HSC) were treated with radiotherapy in our hospital from July 2000 to May 2007. Their clinical data were retrospectively analyzed. Results: 5 cases of EG were treated with tumor partial excision and radiation, while the other 3 cases of EG were given radiation alone after biopsy. The HSC was administered with radiation and endocrine therapy. All the patients were followed up for 1.5-8 years. The response rate was 89%. Conclusion: Radiotherapy of LCH is an effective modality, but the optimal dose needs to be further studied.

Objective To explore the CT and MR imaging features and differential diagnosis of the prostate sarcoma.Methods CT and MRI findings of prostate sarcoma in 4 patients confirmed by pathology were retrospectively analyzed with literature review.Results All cases underwent plain CT scan and one case underwent contrast-enhanced CT scan,MR imaging was performed in 2 cases.The prostates were increased obviously in volume,the average anterior-posterior diameter was 60.5 mm in all cases,lobulated heterogeneous low-density with lowest-density in the center and the tumors were undefinitive with surrouding structures in 3 cases,1 case showed oval homogeneous low-density with sharp margin on plain CT scan.On contrast-enhanced CT,the lesions appeared as heterogeneous enhancement in periphery of prostates and no enhanced at the centre.MRI showed heterogeneous hypo-signal intensity on T1WI and miscellaneous slight high-signal intensity at center and hyper-signal intensity at periphery on T2WI.Conclusion CT and MRI are the effective methods in diagnosing the prostatic sarcoma.

Objective To discuss CT and MRI manifestations and the differential diagnosis of hepatic tuberculosis.Methods The imaging manifestations of hepatic tuberculosis proved by pathology in 2 cases were analyzed retrospectively with literatures review.The plain and contrast-enhanced CT scans were performed in 2 cases and 1 case underwent plain MRI.Results On plain CT scan,the lesion was non-homogeneous low density with even more low density in the center in 1 case,and nearly isodensity in another case.On contrast-enhanced CT scan,the lesions were no enhancement in arterial phases,and slight enhancement in venous phase and balance phase.In 1 case,slight enhancement was also shown surrounding the necrotic area.On MR plain scan,the lesion demonstrated low signal intensity on T_1WI,iso-and high mixed signal intensity on T_2WI.Conclusion Hepatic tuberculosis is rare seen,so it is easy to misdiagnosis.CT and MRI scanning can demonstrate some features of hepatic tuberculosis,especially dynamic enhanced scanning is very helpful in diagnosis and differential diagnosis.

ObjectiveTo observe the expression of apoptosis factor, the mechanism of neuronal apoptosis and profective effect of recombinant Human Erythropoietin (rHu EPO) after spinal cord injury (SCI) in SD rats.Methods30 SD rats were divided into four groups including control group, SCI group, treatment groups A and B.The animal SCI model was established with Allen's method. The changes of nerve functions of rats of 4 groups were observed before and after treating with rHu EPO. The expressions of apoptosis factors (Bcl-2,Bax,Fas) were tested with immunocytochemistry technique, and apoptosis neurones were labeled with TUNEL dyeing.ResultsThe grade of nerve function was improved distinctly in treatment groups, but group B was better than group A.The number of the positive cells for Fas and Bax in SCI group was more than that in treatment groups (P<0.05), and group A was more than group B. The number of Bcl 2 positive cells in the treatment groups was greater than that in SCI group (P<0.05).ConclusionApoptosis is a important death mode of neuron after SCI. rHu EPO can distinctly improve the comeback of the nerve function and protect the nerve tissue.

ObjectiveTo investigate the expression of caspase-3 in the brain of acutely pentylenetetrazole(PTZ)-kindled rats.MethodsThe caspase-3 positive cells were revealed using immunohistochemical SP method. CMIAS image analysis system was used to analyse the expression of caspase-3 hemi-quantitatively. ResultsFollowing PTZ induced epilepsy, the expression of caspase-3 increased both in the hippocampus and in the cortex, and that was more remarkable in the hippocampus than in the cortex.ConclusionCaspase-3 may be activated during neuronal apoptosis after epilepsy. Hippocampus is more sensitive to the neuronal damage due to epilepsy than the cortex is.

Objective To evaluate the usefulness of magnetic resonance spectroscopic imaging in detecting local recurrence in patients with T3N0M0 prostate cancer after cryotherapy.Methods Sixty-five patients with T3N0M0 prostate cancer underwent cryotherapy.The preoperative data of conventional MRI,MRS,transrectal ultrasound (TRUS)-guided prostate biopsy were collected.After cryotherapy,the prostate specific antigen (PSA) of all patients was detected monthly.If PSA ＞5 μg/L,MRI,MRS,and TRUS-guided prostate biopsy were planned within a week.If PSA was unremarkable,MRI,MRS,and TRUS-guided prostate biopsy were planned 12 months after cryotherapy.The prostate was divided 6 regions and the cancerous and noncancerous were marked.The signal-to-noise ratio(S/N) of choline (Cho),citrate (Cit)and the ratios of Cho + creatine ( Cre)/Cit of each regions were measured in pre-operation and postoperation.The patients were divided into non-recurrence and recurrence group according to TRUS-guided biopsy.The S/N of Cho,Cit,and the ratio of Cho + Cre/Cit were compared between the groups before and after cryotherapy by using independent samples t-test.Results ( 1) Fifteen patients were confirmed local recurrence 12 months after cryotherapy,including 11patients with an evaluate PSA level and 4 patients with PSA umemarkable.(2) The S/N of Cho,Cit and the ratios of Cho + Cre/Cit in the cancerous and noncancerous regions before cryotherapy in the sixty-five patients were 25 + 9,11+ 5,and 18 + 5,and 39 ±12,2.33 +0.60,and 0.53 ± 0.19.There had significant difference between that of two groups ( t values were 11.36,9.81,and 13.39,respectively,P =0.00).(3) In the patients with non-recurrence,The S/N of Cho,Cit in the cancerous and noncancerous regions were 4 ± 2 and 3 ± 2 ( t =1.024,P =0.305 ),and 2 +2 and 4 ±3 (t =1.147,P =0.178) and no difference was found.In necrotic area,the ratios of Cho + Cre/Cit could not be calculated because of low level of the S/N of Cho and Cit.(4)In the patients with local recurrence after cryotherapy,the S/N of Cho and Cit in the cancerous and noncancerous regions were 17 ±3 and 3 ± 2 ( t =17.24,p =0.00 ),9 ± 2 and 3 ± 3 ( t =23.66,P =0.00 ) and a significant difference was found.The ratio of Cho + Cre/Cit in the recurrent area was no significant different compared with that of preoperation(t =1.214,P =0.256 ).In necrotic area,the ratios of Cho + Cre/Cit could not be calculated because of low level of the S/N of Cho and Cit.Conclusions MRS is a useful tool to evaluate the changes of the S/N of Cho and Cit,the ratios of the Cho + Cre/Cit and help diagnosis of local recurrence.