1.X-ray and CT Diagnosis and Differential Diagnosis of Nonossifying Fibroma:A Report of 29 Cases
Li LI ; Maofeng GUO ; Liang GUO
Journal of Practical Radiology 2001;0(06):-
Objective To study X-ray and CT diagnosis and Differential diagnosis of nonossifying fibroma.Methods 29 cases of nonossifying fibroma proved by pathology were included in this paper.29 cases underwent radiography and 12 cases underwent CT scan.There were 22 male and 7 female,with age ranged from 5~59 years(mean age 21.3 years),X-ray and CT findings of tumors were analysed.Results The tumors were located in long bone in 27 cases,in which 17 cases were located in metaphses,2 cases in diaphyses,8 cases in bone end and 2 cases in irregular bone.The maximum diameter of tumors ranged from 0.5~7 cm.The tumors were round,oral or mild lobular in 21 cases,the tumors were showed sclerotic borders in 26 cases.Septum was demonstrated in 22 cases on X-ray plain films,but only 2 cases on CT.Bone expansion was showed in 13 cases.Conclusion Most of nonssifying fibroma have characteristic X-ray and CT findings,the diagnosis be identified by X-ray and CT before operation.
2.Measurements and analysis of breast morphology changes after breast augmentation by 3D scanning
Liang GUO ; Dong LI ; Jianning LI
Chinese Journal of Medical Aesthetics and Cosmetology 2011;17(1):15-18
Objective To evaluate the application of three-dimensional (3D) scanning in the measurements and analyses of breast morphology changes that occur after breast augmentation. Methods Pre- and postoperative breast 3D images were obtained in 18 patients (36 breasts) undergoing augmentation mammaplasty by 3D scanning. All implants were round sillicone and planted under pectoral muscle. Average implant volume was 232.2 mL, and average projection was 3.46 cm. The number of implants in low profile implant group was 12( h < 3.0 cm), and 16 in moderate group ( 3.0 ≤ h < 4.0 cm), 8 in high group ( h ≥ 4.0 cm). The following parameters were measured by Geomagic 10.0: volume, projection, angle and distance of key landmarks, and symmetry degree. Results The increased volume of breast was corresponding with the implant volume (P >0.05). Postoperative breast projection was 12.9 %, less than expected projection (preoperative + implant projection). The values in low, moderate, and high profile group were 5.2 %, 15.1%, and 20.2 %,respectively. Conclusion 3D scanning is a quick, convenient, accurate and non-contact method for measurement of breast morphology, and it is promising in breast plastic surgery in the future.
3.Transplanting umbilical cord blood mesenchymal stem cells in ovarian cancer chemotherapy
Xia LI ; Donghui WANG ; Liang GUO
Chinese Journal of Tissue Engineering Research 2016;20(41):6151-6157
BACKGROUND:Existing evidence has confirmed that umbilical cord blood mesenchymal stem cel s have an effect on functional recovery of a variety of damaged cel s.
OBJECTIVE:To explore the effect of umbilical cord blood mesenchymal stem cel transplantation on ovarian cancer chemotherapy.
METHODS:Sixty healthy adult female Wistar rats were randomly divided into normal control group, damage group and treatment group (n=20/group). There was no treatment in the control group, and a rat model of ovarian cancer chemotherapy damage was made in the damage group and treatment group. After successful modeling, rats in the control group were given normal saline injection via the tail vein, and those in the damage and treatment groups were given paclitaxel chemotherapy and pacligaxel chemotherapy plus umbilical cord blood mesenchymal stem cel transplantation, respectively. After transplantation of 2 weeks, mRNA and protein expressions of XAF1 and Survivin in ovarian tumor tissues were detected by RT-PCR and western blot assay, respectively. Apoptosis in ovarian cancer cel s were detected using TUNEL method.
RESULTS AND CONCLUSION:Compared with the damage group, a significant up-regulation of XAF1 mRNA and protein but a remarkable down-regulation of Survivin mRNA and protein were obtained in the treatment group (P<0.05). A severe damage to the ovarian tissues was visible in the damage group, presenting with large hemorrhage and necrosis area. This damage was markedly reduced in the treatment group. Additional y, the apoptotic rate of ovarian cancer cel s was significantly higher in the treatment group than the damage group (P<0.05). Al these findings indicate that umbilical cord blood mesenchymal stem cel transplantation aids in ovarian cancer chemotherapy to promote ovarian tissue repair in rats, and XAF1 and Survivin cannot be ignored in tumor angiogenesis and ovarian cancer cel apoptosis.
4.Meta-analysis of Consciousness-Restoring and Orifice-Opening Acupuncture Manipulation in Treating Stroke
Hui LI ; Weixiong LIANG ; Xinfen GUO
Journal of Guangzhou University of Traditional Chinese Medicine 2001;0(03):-
Based on the principle of evidence-based medicine, the efficacy and safety of consciousness-restoring and orifice-opening (CROO) acupuncture manipulation in treating stroke are systematically assessed. All reports of clinical trials of CROO acupuncture manipulation in treating stroke were collected and random-effect model of Meta-analysis was performed by using the statistical software of Review Manager (RevMan4.1). Sensitivity and heterogeneity were analyzed and tested; funnel-plot analysis was used to identify the publication bias. Comprehensive efficacy (Odds Ratio, OR) of CROO acupuncture manipulation in treating stroke was: OR of cure and markedly effective rate between groups being 3.65 and 95% confidence interval (CI) in the range of 1.70~7.83, OR for decreasing long-term death rate being 0.21 and 95% CI in the range of 0.08~0.52. Stratified analysis showed that OR of stroke sequela was 4.01 and OR of cerebral vascular infarction was 4.45. Adverse drug reaction was not found in all of the reports. Funnel-plot analysis showed the possible existence of publication bias. [ Conclusion]CROO acupuncture manipulation has certain effect in treating stroke, especially in treating acute stage of cerebral vascular infarction, and could reduce long-term death rate of stroke. Heterogeneity may result from the difference of trial designs and inclusive criteria. Funnel-plot analysis shows the possible existence of publication bias. This conclusion is rather limited and will get more evidence if multi-center, double-blinded, randomized and controlled trials could be carried out.
5.Post-traumatic Stress Disorder and Self-esteem Among Workers after Wenchuan Earthquake
Li GUO ; Huani LIANG ; Guihao LIU
Journal of Medical Research 2006;0(11):-
Objective To investigate the prevalence and symptoms of post - traumatic stress disorder(PTSD) and the self-esteem of the workers at mineral processing plant 45 days after Wenchuan earthquk. Methods PTSD Checklist Civilian version(PCL - C) , Self -Esteem Scale(SES) , Simplified Coping Style Questionnaire and a self- designed questionnaire were administered to a sample of 81 workers one and a half month after Wenchuan earthquake. Results The prevalence of PTSD among the workers was 26.3% , and the mean total scores of PCL - C was 39.63?10.73.The prevalence difference between the male and the female was not statistically significant (P =0.527). The top psychological activity was worry (86.8%). The mean self- esteem score had no statistical difference with domestic normal level(t = -0.484,P =0.630). Neither self - esteem(P =0.469) nor coping style(P =0.780) was associatied with PCL -C total scores. Conclusion To act more effectively in the intervention, it is important to exactly understand the normal stress response after severe disaster, and correctly grasp the key point in different stage.
6.Advancement of study on matrix metalloproteinase 3 and significance of its application in forensic medicine
Xiaochong GUO ; Rubo LI ; Hongxia LIANG
Chinese Journal of Forensic Medicine 1987;0(03):-
Matrix metalloproteinase 3 is one of matrix metalloproteinase family members, which degrades a wide range of components of the extracellular matrix and participates in tissue morphogenesis, wound healing and inflammation. In addition, matrix metalloproteinase 3 is involved in pathogenesis and progress of a spectrum of diseases and malignant tumors, such as rheumatic arthritis, arteriosclerosis, breast cancer, and so on. Recent studies have demonstrated that matrix metalloproteinase 3 may be a novel signaling proteinase from apoptotic neuronal cells to microglia, which results in degeneration of neurons in Alzheimer's disease and Parkinson's disease by activating microglia. There is also an association between genetic polymorphisms of matrix metalloproteinase 3 at promoter region 5A/6A and susceptibility of myocardial infarction. Decrease in serum concentration of matrix metalloproteinase 3 after myocardial infarction may be a useful parameter for diagnosing sudden death due to myocardial infarction in forensic practice. Expression of matrix metalloproteinase 3 varies with different types of brain injuries, suggesting that it may contribute to synaptic plasticity during functional recovery. To elucidate the time-dependent expression of matrix metalloproteinase 3 may provide a new way for wound age determination in the brain.
7.Foundation and Management of Medical Ethics Evaluation Institution will Benefit Long-term Medical Ethics Mechanism
Hongjuan LIANG ; Gang LI ; Zhaojiang GUO
Chinese Medical Ethics 1994;0(05):-
Evaluation of medical ethics aims to combine the estimation forms and the administration.Foundation and management of medical ethics evaluation institution will benefit long-term medical ethics mechanism.More attention should be paid to the following aspects as follows.First,much education is in need to elucidate the essence and importance of medical ethics evaluation institution as well as long-term medical ethics mechanism.Second,stringent management is required to have medical ethics mechanism work well.Third,continuous supervision of the faculty will promoting the long-term medical ethics construction.
8.Document Management of Medical Ethics Evaluation and Its Practical Application
Hongjuan LIANG ; Gang LI ; Zhaojian GUO
Chinese Medical Ethics 1994;0(06):-
Document management of medical ethics evaluation includes medical staff's correlated information showed in medical practice.The information conveyed in the documents can be applied in many fields including medical ethics research,medical ethics management,and professional ethics construction,etc.The establishment,application and management of the document are of great importance for medical ethics construction.
9.Clinical assessment of one-visit root canal therapy for vital teeth
jian-hui, DONG ; guo-liang, LI
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(07):-
0.05).It was revealed that all the patients followed up 3 to 6 months after treatment were free from complaints of the involved teeth,with nomal food intake and mastication.No abnormal adjacent tissues of dental roots were detected by imaging examination.Conclusion For the vital teeth,the similar clinical effect may be obtained by one-visit RCT and multi-visit RCT.
10.Reflection on the Implementation of Medical Ethics Evaluation
Hongjuan LIANG ; Gang LI ; Zhaojiang GUO
Chinese Medical Ethics 1995;0(03):-
In the evaluation procedure of medical ethics,it is important to inspect and estimate objectively medical staff's correlated information showed in medical events.Satisfying evaluation of medical ethics can be attributed to the following premises including scientific evaluation regimes,just administration,objective and comprehensive evaluation procedures,just evaluation criteria and archives of medical ethics evaluation.