Objective To study clinical characteristics of the patients with enosinophilic gastroenteritis(EG) and analyze the cause of misdiagnosis.Methods 6 cases of EG were analyzed in clinical characteristics,laboratory tests and endoscopy.The clinical characteristics of EG and the possible cause of misdiagnosis were studied.Results ⑴EG have a various clinical manifestation.The mucosal type have the commonest symptoms,such as epigastric pain,diarrhea.The serosal type was presented with abdominal pain,bloating.and ascites,accompanied with nausea,vomiting and low fewer.The patients in the muscular type had bowel obstruction symptom.⑵Enosinophilic counts in peripheral and bone marrow had high level(43 5?20 5)%,and it was related with condition of illness.⑶ESR,CRP and FIB were in normal range,but the IgG was low level.⑷The ascites were effusion with eosinophilia.⑸Endoscopies showed erosion and edema in antrum,duodenum and cecum,accompanied with eosinophilia infiltration in mucosa.⑹The steroid hormone therapy responsion was sensitive and all symptoms were relieved and eosinophils was recovered to normal value within one week.⑺Though their symptom recurrence was probable,good prognosis was got.Conclusions The key point for diagnsos is eosinophilia counts in peripheral blood and ascites.The biopsy of the gastrointestinal tract mucosa is also very important and helpful.

Objective To study the risk factors of acute exacerbation of chronic obstructive pulmonary disease(AECOPD) induced by community-acquired Pseudomonas aeruginosa(PA) infection which provides the basis for early clinical intervention in high-risk patients.Methods Retrospective analysis of clinical data from 236 patients with acute exacerbation of COPD was conducted in Department of Respiratory Medicine of our hospital from January 2015 to December 2015.The patients were divided into PA group(n=44)and the non-PA group(n=192)according to respiratory tract pathogen infection.The univariate analysis and multivariate logistic regression analysis were performed between the two groups to analyze risk factors for AECOPD induced by PA infection.Results Univariate analysis showed that hypoalbuminemia,AECOPD-induced hospitalization in the recent one year,application of broad spectrum antibiotic within recent 90 days,intermittent use of systemic corticosteroids within recent 90 days,lung function grading of GOLD3/4 level in COPD,acute exacerbation frequency＞ 1 time in last year,the BODE index,walking distance during six minutes,mMRC grading,and CAT scores were significantly correlated with occurrence of community acquired PA-induced AECOPD(all P＜ 0.05).Logistic regression analysis showed that higher BODE index,AECOPD-induced hospitalization in the last year,the use of broad spectrum antibiotic within 90 days and hypoalbuminemia were independent risk factors for community acquired PA induced-AECOPD(OR =14.573、18.958、4.170、5.112,all P＜0.05).Conclusions We suggest that the COPD patients having a higher BODE index scores should be clinically intervened early to reduce the occurrence of AECOPD-induced hospitalization,should receive active etiology examination,and should receive therapies for community-acquired Pseudomonas aeruginosa (PA)infection with specific narrowspectrum antibiotics according to the drug susceptibility and multiple comprehensive measurements,and for correcting hypoalbuminemia.

Objective: To explore influence of exercise training and angiotensin-converting enzyme inhibitor (perindopril) on blood pressure, aortic compliance and cardiovascular tissue structure in spontaneously hypertensive rats (SHR). Methods: A total of 38 SHR aged seven weeks were divided into control group (C group, n=9), exercise group (Exe group, n=9), perindopril group (Per group, n=10) and perindopril + exercise group (Per＋Exe group, n=10). SHRs were observed for eight weeks, and tail-cuff method was used to measure systolic blood pressure（SBP）once a week. When rats were 15 weeks old, regression line（once linear function）was obtained by single regression analyzing the relation between blood pressure and pulse wave velocity（PWV）. The b of this once linear function was used as index of aortic compliance（there was negative relationship between b and aortic compliance）. The left ventricular mass （LVM）/body weight（BW）was used to evaluate ventricular thickening, and aortic weight （AO）/ BW was regard as index of vascular thickening. Results: Compared with C group, SBP of Exe group significantly decreased on 12 weeks old (P<0.01) and 13 weeks old (P<0.05), but decrease of SBP was no significant on 14 weeks old（P＞0.05）. SBP of Per group and Per+ Exe group on eight weeks old immediately decreased to level of seven weeks old (P<0.0001),but there was no significant difference between the two group（P>0.05）. On 15 weeks old, the LVM/BW [(2.19±0.36) mg/g, (2.16±0.32) mg/g ] and AO/BW [(0.20±0.01) mg/g, (0.19±0.01) mg/g] of Per group and Per+ Exe group significantly decreased compared with C group [(2.95±0.58) mg/g, (0.26±0.01) mg/g], P<0.05 all, but there was no significant difference in these indexes between Per group and Per+ Exe group and between C group and Exe group（P＞0.05 both）. The b （index of aortic compliance）were [（C group ：（21.2±1.2）, Exe group：（20.5±1.4）, Per group：（14.8±1.6），Per＋Exe group：（15.0±1.3）] respectively, there was no significant difference between Per group and Per+ Exe group and between C group and Exe group（P＞0.05 both）. Conclusion: The exercise training of eight weeks possesses certain lowering blood pressure tendency, but no significant influence yet for aortic compliance and cardiovascular tissue structure in spontaneously hypertensive rats.

Hemophagocytic lymphohistiocytosis (HLH) is characterized by hemophagocytosis and a reactive process resulting from prolonged and excessive activation of antigen presenting cells (macrophages,histiocytes) and CD8+ T cells.The majority of genetic causes identified to date affect the cytotoxic function of NK and T cells,crippling immunologic mechanisms that mediate natural immune contraction.The predominant clinical findings of HLH are fevers (often hectic and persistent),cytopenias,hepatitis and splenomegaly.Due to the life-threatening implications of the diagnosis of genetically determined HLH,antiinflammatory therapy,often consisting of steroids,etoposide or antithymocyte globulin,should be instituted promptly,followed by curative hematopoietic cell transplantation.Secondary HLH,associated with autoimmune disorders or viral infections in teens and adults,should control the primary inflammatory.

Objective A solution of serial communication in Multi-Axis Controller which uses programmable multi-axis controller (PMAC) as down processor and PC as up processor is introduced. By the PComm32.dll provided with Delta Tau Data Systems Inc., the serial communication between PC and PMAC is realized based on .NET. Methods In order to realize the programming techniques of serial communication, a new method that managed codes invoked the unmanaged codes in Common Language Runtime environment by using Platform Invocation Services was adopted. The serial communication program was designed by using the program language C#. Besides the single axis locomotion,the debugging procession of the multi-axis joint locomotion was also recounted based on the five-DOF robot. Results The results indicated that the serial communication between PC and PMAC was completely realized. Conclusion The developed serial communication software module is of good correctness, stability and reliability, and also shows that the software is convenient and easy to use, which can accord with system requirements.

The current situation of medical metrology is expatiated and the advantages of medical metrology room is introduced. Some kinds of equipment can't be measured. Doctors and nurses don't attach enough importance to medical metrology work. Countermeasures are put forward.

In order to enable centralized oxygen supply a healthy development,this paper introduces five kinds of mistakes in the application of centralized oxygen supply technique.

Solid internal pressure is one of the important parameters in traffic bridge and defense field.However, the existing testing equipments have the defects of serious electromagnetic interference, poor reliability, and poor accuracy.To overcome the above problems, a fiber bragg grating (FBG) high pressure solid pressure sensor which used thin plates as elastic bearing diaphragm and applied the deflection under pressure to pull the pressure sensitive grating to realize pressure sensing axial displacement was designed.By calculating on the structure according to the measurement range and finite element simulation, its feasibility was confirmed.In the laboratory with constant temperature, the pressure calibration experiment was carried out, and the temperature compensation was performed by the temperature compensation grating in the same temperature field to correct the temperature drift of strain grating.Experimental results showed that the newly devised FBG pressure sensor could sense the pressure as high as 50 MPa, with a linearity of 99.2%.

PurposeTo analyze fluorodeoxyglucose (FDG) PET/CT images in patients with probable sporadic Creutzfeldt-Jakob disease (sCJD) and the affected encephalic regions by statistical parameter mapping (SPM) so that image information can be provided for early clinical diagnosis.Materials and MethodsSeven patients with probable sCJD diagnosed according to the WHO criteria and 2009 clinical diagnosis criteria and 7 controls at the matched age were enrolled in the study. Both groups underwent FDG PET/CT scan and the images were analyzed visually and by SPM.ResultsThe visual analysis showed that the patients with probable sCJD had a hypometabolism in the wide pallium and basal ganglia region and that a portion of patients mainly had a lateral decrease. The SPM analysis exhibited that patients in sCJD group had a pattern of hypometabolism that affected bilateral parietal, frontal, occipital cortices and head of caudate (P<0.05) and indicated that the patients with lateral hypometabolism existed crossed cerebella diaschisis (P<0.05).ConclusionFDG PET/CT image features of sCJD patients present a hypometabolism in the wide pallium and basal ganglia region, which may be helpful in the diagnosis of sCJD in certain clinical situations.

Objective To examine the association between baseline body mass index (BMI) and overall survival (OS) in lymph node negative breast cancer patients. Methods From Jan. 1st, 1998 to Dec. 30th, 2008, 662 patients with lymph node negative breast cancer were treated at the Breast Center of Peking University Peo-ple’s Hospital. The clinical factors such as menopause status, tumor stage, body mass index (BMI), total triglyc-eride (TG), total cholesterol (TC) and glucose (GLU) were collected. The chi-square test was used to assess the association between obese and other factors. Log-Rank test and Cox regression analysis were performed to make univariate and multivariate analysis. Results The median follow up was 82 months (ranging from 2 to 209 months). The 5-year and 10-year survival was 93% and 82%. Obesity was associated with GLU and tumor stage (χ2=5.224, P=0.031; χ2=6.007, P=0.14), whereas there was no relationship between obesity and other factors. The Log-Rank test revealed statistically significant better survival for non obesity (χ2=4.693, P=0.030), normal GLU (χ2=4.678, P=0.031) and HR positive patients (χ2=7.837, P=0.005). COX regression analysis showed that BMI (χ2=3.874, P=0.049) and HR status (χ2=6.782, P=0.030) had independent influence on overall survival of node negative breast cancer patients. Conclusion Obesity is an adverse prognostic factor for lymph node negative breast cancer patients, which may be associated with obesity-related disorders such as high blood GLU.