China ; Combined Modality Therapy ; Esophageal Neoplasms ; pathology ; surgery ; therapy ; Esophagectomy ; methods ; Humans ; Lymphatic Metastasis ; Neoplasm Staging ; Survival Rate

BACKGROUND:Recent studies have shown that osteoclast differentiation factor is closely related to osteoclast differentiation, formation and function in bone remodeling during orthodontic tooth movement. OBJECTIVE:To observe the effects of three kinds of orthodontic appliances on the expression of osteoclast differentiation factor at the pressure side of rat periodontal tissue during remodeling process and to explore the biocompatibility of the orthodontic appliances with the host tissues during orthodontic treatment. METHODS:Eighty healthy Wistar rats were selected to establish animal models of orthodontic tooth movement, and then randomly divided into four groups: control group, MBT group, Begg group, Damon Ⅲ appliance group. Four animal from each group were sacrificed at 3, 7, 14 days after wearing orthodontic appliances. The tartrate-resistant acid phosphatase staining was used to count the osteoclasts at the pressure side of alveolar bone tissue; real-time quantitative PCR detection to detect mRNA expression of osteoclast differentiation factor at the pressure side of periodontal tissue and time distribution characteristics. RESULTS AND CONCLUSION:Compared with the control group, the number of positive osteoclasts and mRNA expression of osteoclast differentiation factor at the pressure side of the alveolar bone tissue were increased with orthodontic time, reached the peaked at 7 days and then gradualy decreased. The number of positive osteoclastsand mRNA expression of osteoclast differentiation factor at the pressure side of the alveolar bone tissue were significantly higher in the Damon Ⅲ group than the other three groups at 7 days after orthodontic treatment (P < 0.05). These findings indicate that, during the bone remodeling, the number of positive osteoclasts changed in accordance with the mRNA expression of osteoclast differentiation factor, and at 7 days, the number of positive osteoclasts and mRNA expression of osteoclast differentiation factor were highest in the Damon Ⅲ group.

BACKGROUND:There is no design that can completely rule out the intermittent impact damage to implants, therefore, a new bal attachment-retained implant system is constantly updated and developed. OBJECTIVE:To evaluate the clinical effectiveness of an implant-supported mandibular overdenture retained with a bal attachment. METHODS: We searched the Cochrane Library, PubMed, Medline, EM-base, WanFang Data, CNKI, VIP and other databases by computer to colect randomized controled trials addressing the implant-supported mandibular overdenture retained with a bal attachment and other control methods for dentures. The time limit was from database creation to February 2014. Two researchers independently completed literature screening according to inclusion and exclusion criteria, data extraction and quality assessment. RevMan 5.1 software was used for meta-analysis. RESULTS AND CONCLUSION: There were 10 studies included in result analysis, including 7 from China and 3 from other countries. Analysis results showed that statistical heterogeneity was remarkable in included studies, and there was no significant difference in patient’s satisfaction, clinical and objective indicators, and complications, suggesting that this approach continues to be explored in clinic. The implant-supported bal attachment-retained mandibular overdenture is relatively expensive, which is identical with the current research progress that is in the exploration stage worldwide. Due to the limited quantity and quality of included studies, the conclusions of this systematic review only provide references for clinical practice and research. The implant-supported bal attachment-retained mandibular overdenture stil needs further exploration and improvement.

Cardiac Surgical Procedures ; methods ; Child ; Child, Preschool ; Combined Modality Therapy ; Coronary Aneurysm ; diagnosis ; etiology ; therapy ; Coronary Artery Disease ; diagnosis ; etiology ; therapy ; Coronary Thrombosis ; prevention & control ; Echocardiography ; Humans ; Mucocutaneous Lymph Node Syndrome ; complications ; Platelet Aggregation Inhibitors ; therapeutic use ; Thrombolytic Therapy ; methods ; Troponin I ; analysis

Objective This study was conducted to investigate the clinical outcomes and safety of primary percutaneous coronary intervention(PCI) combined with tirofiban therapy in patients with acute ST segment elevation myocardial infarction(STEMI). Methods Seventy-one consecutive patients with acute STEMI were divided by random number table to primary PCI combined with tirofiban therapy group(Tirofiban group,25 cases) and primary PCI treatment alone group(Control group,46 cases). Left ventricular ejection fraction(LVEF) and major adverse cardiac events rates(MACE) during hospitalization period and at 30 days discharge and 180 days after discharge were compared between the two groups. Results TIMI grade flow was significantly different between the tirofiban group and control group after surgery. The LVEF and MACE were significantly different between two groups during hospitalization period and at 30 days after discharge. The MACE at 180 days followup was relatively reduced and LVEF was relatively improved in tirofiban group, but there was not significantly different. Conclusion Adjunctive therapy with tirofiban for patients with acute STEMI who underwent primary PCI was safe and effective.

Objective To explore the mechanism of personality between attachment and defense style in college students. Methods 291 students were surveyed with Eysenck Personality Questionnaire-R Short Scale (EPQ-RSC, Chinese Adaptation), Experience of Close Relationship Inventory(ECR, Chinese Adaptation) and Defense Style Questionnaire ( DSQ). Results ①Unmature defense style had significant positive correlations with anxiety, avoidance, neurotism and psychoticism(r = 0. 19,0.45,0.51,0. 19, P<0.01) ,and had significant negative correlation with extroversion(r= -0. 25, P<0. 01 ) . ②Extroversion acled as part meditator between attachment and unmature defense style. ③Neurotism served as part meditator between anxiety and unmature defense style. Conclusion Attachment is a remarkable predictor of unmature defense style and has indirect influence on it through neurotism and psychoticism.

Objective To analyze the effect of Evidence-based Care on the complication rate and comfort in patients with coronary heart disease after intervention therapy, and to provide reference for clinical care. Methods One hundred and twenty-two patients with interventional treatment of coronary heart disease in hospital from May 2013 to April 2015 were selected, patients were divided into control group (61 cases) and intervention group (61 cases) according to the care methods. Control group patients were given careful routine care, Intervention group patients were given Evidence-based Care, the complication rate and comfort of the two groups were compared. Results The incidence of postoperative complications in the intervention group (11.5%) was significantly lower than the control group (76.6%),P<0.05. The intervention group after 6h (61.5 ± 5.3), 12h (70.2 ± 4.5), 24h (87.5 ± 3.5) comfort were significantly higher than control group 6h (52.6 ± 6.8), 12h (61.2 ± 5.3), 24h (73.5 ± 4.2), P<0.05. The incidence of bad mood of intervention group were significantly lower than the control group, P<0.05. The intervention group patient care satisfaction (96.7%) was significantly higher than control group (86.9 %), P<0.05. Conclusion Evidence-based nursing for the patients with coronary heart disease undergoing PCI can greatly decrease vascular complications and improve comfort value.

China ; Esophageal Neoplasms ; surgery ; Esophagectomy ; history ; History, 20th Century ; History, 21st Century ; Humans ; Lung Neoplasms ; surgery ; Thoracic Surgical Procedures ; education ; history

Objective Look into the therapy of Chinese traditional medicine for agedness osteoarthritis and osteoporosis. Methods 56 osteoporosis suffers take the Chinese traditional medicine orally three months. Look into the suffers symptom, bone density and biochemical markers. Results For three months treatment, the suffers symptom is catabatic. The serum calcium, serum phosphorus and bone density are higher than before, t-teat, P＜0.05.The serum bone glaprotein(BGP), bone specificalkaline phosphatase(BALP) and 24 hours urine calcium are lower, ttest, P＜0.01. Conelnsion The therapy of Chinese traditional medicine for agedness osteoarthritis and osteoporosis is prominence and safe.

Leukoaraiosis (LA) is not only found in patients with vascular dementia,Alzheimer's disease,brain trauma,carbon monoxide poisoning Binswanger's disease,mild cognitive impairment,diabetes,but also have a certain proportion in the normal elderly.This article reviews the advances in research on the risk factors,pathogenesis,pathological changes,clinical manifestations,imaging characteristics and treatment of LA.