With the development of the society,general surgery teaching has faced higher demands.This paper mainly discusses how to increase comprehensive quality,medical ethics and manipulation capability of the surgeons.

Xintai Tablets,mainly composed of is the National Grade C of Chinese herb medicine newly developed by the Acadamy of TCM of Hunan Province,Institute of Chinese Herb Medicine.The new certification number of the Ministry of health is WEIYAOZHENGZI 1997-Z-055.Its clinical investigation was undertaken during four hospitals(the First Hospital Affiliated to Hunan College of TCM,etc.)in 1995.It suits well to those patients who suf- fered from the chest pain with the heart-blood stasis or heart-blood stasis and defifiency of heart-yin concomitantly.The clinical investigation on 307 cases indicated that the obvious ef- fective rate for the chest pain with angina pectoris is 56.02% with 93.48% of overall effec- tive rate,for the electrocardiogram is 34.38% with 62.28% of overall effective rate,for over 80% of stopping or reducing nitroglycerin is up to 40.69% ,over 50% of stopping or reducing nitroglycerin is up to 87.75%.The obvious effective rate of synthesis curative effect is 50.49% with 91.86% of overall effective rate.

OBJECTIVE: To develop a HPLC method for the determination of the concentration of caffeic acid, chlorogenic acid and 1, 3-dicaffeoylquinic acid in rat urine and to observe the excretion of three compounds in rats. METHODS: Rat urine samples, collected at different intervals after vein injection of Dengzhanxixin injection traditional Chinese medicines, added with protocatechuic aldehyde as internal standard, handled by ethyl acetate, then were measured by HPLC. RESULTS: The recoveries of caffeic acid, chlorogenic acid and 1, 3-dicaffeoylquinic acid were about 95%-98%, 90%-95%, 95%-97%, respectively. The cumulative excretions of caffeic acid, chlorogenic acid and 1, 3-dicaffeoylquinic acid in urine within 60 h were (70.97 ± 7.31)%, (87.62 ± 12.23)% and (9.87 ± 2.63)%. Relative standard deviation(RSD) of intra- and inter-day assay was less than 10%. CONCLUSION: The established method is simple, accurate and specific. It can be successfully used for the analysis of three compounds in rat urine.

Objective To observe the feasibility and safety of dexmedetomidine used in motor evoked potentials(MEP)monitoring in patients undergoing neurosurgery.Methods Thirty ASA Ⅰ orⅡ patients,male 1 5 cases,female 1 5 cases,aged 20-60 years,weighing 40-80 kg undergoing neuro-surgery receiving MEP monitoring were randomly divided into 2 groups (n =1 5 each):control group (group C)and dexmedetomidine group (group D).In group D,dexmedetomidine 0.5 μg/kg was in-fused over 10 minutes before anesthesia induction,and then was infused at a rate of 0.5 μg·kg-1 · h-1 toward the end of operation.Group C received the equal volume of normal saline.HR,MAP and BIS were recorded at admission to the operating room (T0 ),skin incision (T1 ),when the muscle re-laxants were stopped (T2 )and 50 minutes later (T3 ).The current intensity and the time when first MEP was induced after muscle relaxant was stopped,the amplitudes and latencies of MEP on thenar muscle at T3 ,the total consumption of anesthetics,and development of adverse effects were also re-corded.Results Compared with T0 ,HR in group C at T1 ,T3 and MAP in group C at T1-T3 was in-creased,HR in group D was decreased at T2-T3 (P <0.05).Compared with group C,HR and MAP were decreased at T1-T3 in group D(P <0.05).The amount of propofol consumed and the current in-tensity inducing MEP were lower in group D than in group C (P <0.05).The amplitude of MEP at T3 was higher in group D than in group C (P <0.05).Compared with group C,the incidences of hy-pertension and tachycardia were decreased in group D,and the incidence of bradycardia was increased (P <0.05).Conclusion Dexmedetomidine used in MEP monitoring in patients undergoing neurosur-gery can meet the operation requirements,maintain hemodynamic stability,reduce the incidences of adverse reactions,and improve monitoring quality of MEP.It is a safe and feasible anesthesia method.

Objective To investigate the effects of different doses of dexmedetomidine used in SEP and MEP monitoring in patients undergoing neurosurgery. Methods Eighty patients undergoing neurosurgery receiving SEP and MEP monitoring were randomly divided into 4 groups(n = 20 each):group C,group D1,group D2 and group D3. In groups D1 ,D2 and D3 ,dexmedetomidine 0.5 μg/kg was infused over 10 minutes before anesthesia induction,and then was infused at a rate of 0.1,0.3 and 0.5μg/(kg·h)respectively toward the end of operation. Group C received the equal volume of normal saline. HR ,MAP and BIS were recorded at admission to the operating room(T1),skin incision(T2),when the muscle relaxants were stopped(T3)and 50 minutes later(T4). The current intensity and the time when first MEP was induced after muscle relaxant was stopped ,the amplitudes and latencies of SEP(N20-P25,N20)and MEP on thenar muscle at T4,the total consumption of propofol,and development of adverse affects were also recorded. Results Compared with groups C and D1,HR and MAP were decreased at T2-T4 in groups D2 and D3(P<0.05). The amount of propofol consumed were lower in groups D2 and D3 than in groups C and D1(P < 0.05). The current intensity inducing MEP was lower and the amplitude of MEP at T4 was higher in group D2 than in groups C,D1 and D3,and the situation was same in group D3 than in group C (P<0.05). No significant change was found in the other parameters in groups C ,D1 ,D2 and D3(P>0.05). Conclusion Dexmedetomidine infused at 0.3 μg/(kg · h) after infusion of a loading dose of 0.5 μg/kg could improve monitoring quality of MEP through reducing the amount of propofol consumed ,have less inhibition on MEP than other groups,have no obvious effects on SEP,andmaintain hemodynamic stability.

Objective To investigate the method and effect of endovascular treatment for ilio-femoral venous post-thrombotic syndrome.Methods We retrospectively analyzed the clinical data of 47 patients,who underwent endovascular treatment for ilio-femoral venous post-thrombotic syndrome from January 2010 to December 2013.Patients received transjugular iliofemoral venous thrombectomy,percutaneous angioplasty (PTA) and/or endovascular stent placement after inferior vena cava filter was implanted.Results All patients were successfully treated with angioplasty and stent placement.The ilio-femoral venous were patent after the placement of the stent.Chronic ulcer in 7 patients healed within one month.The patency rate of the affected limb at 6 months was 88.9％,occlusion rate was 11.1％.No reblocked cases were found during venous ultrasound follow-up.After treatment,the circumference difference of low limb between affected and normal limb decreased from (2.46 ± 0.98) cm to (0.70 ± 0.19) cm (P ＜0.05) at the level of 15 cm above knee,and from (3.28 ±0.85) cm to (0.83 ±0.26) cm (P＜0.05) at the level of 15 cm below knee.Villalta score decreased from (12.0 ± 1.9) to (6.9 ±2.2,P ＜ 0.05) and symptoms were significantly improved.Conclusions Ilio-femoral venous stenting provides a safe,effective and minimal invasive approach for the treatment of post-thrombotic syndrome.Acceptable patency rates can be expected through short-term follow-up.

Objective To investigate the early diagnostic methods for sub-clinical hepatic encephalopathy (SHE).Methods 46 hepatocirrhosis patients without hepatic encephalopathy (SHE group) were recruited to perform P300, brainstem auditory evoked potential (BAEP), numeral connection teat (NCT),mini-mental state examination (MMSE)and electroencephalogram (EEG), compared with 43 unhepatopathy patients (control group) and within following up.Results The P300 delitescence and the NCT value in SHE group were obviously longer than those of the control group (allP

Objective To explore the role of atorvastatin resist to tobacco smoking inducing endothelial inflammation .Meth‐ods HUVECs were divided into normal control group ,cigarette smoking extract(CSE) group and atorvastatin(AS)+CSE group . The cellular morphology of HUVECs in three group were observed ,then the expressions of VCAM‐1 and E selectin in HUVECs in three group were detected by western blot assay .Results In CES group ,drastic morphological change of HUVECs were observed . In AS+CSE group ,minor morphological change of HUVECs were observed .Also ,the protein levels of VCAM‐1 and E selectin were much higher in CSE group than that of in other two groups(P<0 .05) ,and the protein levels of VCAM‐1 and E‐selectin in AS+CSE group were a little higher than that of in control group ,but much lower than that of in CSE group(P<0 .05) .Conclusion Our results showed that atorvastatin might partly resist to tobacco smoking inducing endothelial inflammation .

Objective: Try to get the information about the civil will of donation of cadaver in Wuhan. Method: Make stochastic visit to the dwellers in Wuchang district of Wuhan and then study the statistical data. Content: Legal system, sensibility, traditional ideas and public opinions etc. Result: The most notable factors are legal system and sensibility. Conclusion: In order to implement the new law,we should strengthen the dissemination of donation of cadaver.

Objective To establish a new automatic lung segmentation method in order to deal with the omission of pleural nodules and pulmonary vessels. Methods Lung parenchyma were extracted from chest CT images with the inversed operation of 2D region growing and connected area classification, then the contours and locating the contour points were traced with scan line searching. Finally, the parameters of lung contour points were analyzed to locate the contours distorted by nodules, and curve spline was used to correct distorted contours. Results The experimental results of many sets of CT images verified that the technique proposed was effective. The comparison with other contour correction algorithm verified that line searching contour correction was superior. Conclusion The proposed algorithm includes tumors in the segment results, and confirms the integrality, veracity, real-time quality of this auto-segmentation method.