1.Immunomodulation Therapy in Children with Aplastic Anemia.
Won Suk SUH ; Ki Sik MIN ; Woo Gun CHOI ; Hack Ki KIM ; Kyoung Sn LEE ; Soon Yong LEE
Journal of the Korean Pediatric Society 1990;33(2):170-177
No abstract available.
Anemia, Aplastic*
;
Child*
;
Humans
;
Immunomodulation*
2.Improvement of Underlying Cause of Death Determination Using Health Related Data Bases from Death Certificates in Which Causes of Death Recorded as Cardiopulmonary Arrest, Nonspecific Symptom, Senility.
Seok Gun PARK ; Woo Sung PARK ; Sun Won SEO ; Kwang Hwan KIM
Journal of Korean Society of Medical Informatics 2003;9(4):469-480
We performed this study to show that it is possible to identify underlying causes of de ath not identif ied by issued death certificates by mapping and adding information from National Database(DB) such as health insurance DB or KUHDDS(Korea Uniform Hospital Discharge Data Sets) with death certificates. We collected 2,986 death certificates issued at Cheonan, Asan provinces and 458 death certificates issued at 3 general hospitals at Chenoan city. Mapping of death certificate data with health insurance DB was possible in 77.4%(Cheonan, Asan provinces) and 87.3%(3 general hospitals at Cheonan city) of cases. Rate of underlying causes of death identified from records on death certificates before mapping was 64.4% and 68.3% each. After mapping and adding information from health insurance DB, the rate increased to 79.8% and 79.2% each. This work was done by skilled medical record officers. We also selected death certificates which recorded the causes of deaths as old age, cardiopulmonary arrest, or nonspecific symptoms. The possibility was shown that old age, ca rdiopulmonary a rrest, and nonspecific symptoms can be corrected by information from mapped health insurance DB and KUHDDS. With these results, we discussed some cause of incorrect recording practices. And we suggested simple but practical method to improve the correctness of death certificates; there is a possibility that comparing death certificates with KUHDDS before it is issued, where available, can improve the quality of death certificate.
Cause of Death*
;
Chungcheongnam-do
;
Death Certificates*
;
Heart Arrest*
;
Hospitals, General
;
Insurance, Health
;
Medical Records
3.Generalized Joint Laxity is Associated with Primary Occurrence and Treatment Outcome of Lumbar Disc Herniation.
Woo Jin HAN ; Hong Bae KIM ; Gun Woo LEE ; Jung Heum CHOI ; Won Jin JO ; Sun Mi LEE
Korean Journal of Family Medicine 2015;36(3):141-145
BACKGROUND: We investigated relationships between generalized joint laxity and primary lumbar disc herniation occurrence and compared clinical outcomes after conservative treatment in lumbar disc herniation patients with and without generalized joint laxity. METHODS: The study group included 128 men, and the control group included 276 men matched for age and body mass index with the study group. The primary outcome measure was the presence or absence of generalized joint laxity using the Beighton scale. Clinical outcomes measured by the visual analog scale and the Oswestry disability index 2 years after conservative treatment were the secondary outcome measure. RESULTS: Generalized joint laxity prevalence was 13.2% in the study group and 5.1% in the control group, a significant difference (P=0.01). Spearman correlation analysis revealed that weight (r=0.162, P=0.03), body mass index (r=0.131, P=0.03), and generalized joint laxity (r=0.372, P<0.01) significantly correlated with lumbar disc herniation occurrence. In multivariate regression analysis, generalized joint laxity was the only significant lumbar disc herniation predictor (P=0.002; 95% confidence interval, 1.08 to 5.26). Generalized joint laxity in lumbar disc herniation patients was associated with worse clinical outcomes after conservative treatment measured by visual analog scale scores for lower extremity pain (P=0.02), lower back pain (P=0.03), and Oswestry disability index scores (P=0.03). CONCLUSION: Generalized joint laxity might be associated with lumbar disc herniation occurrence and might also be a negative predictor of worse clinical outcomes after conservative treatment.
Body Mass Index
;
Humans
;
Intervertebral Disc Displacement
;
Joint Instability*
;
Low Back Pain
;
Lower Extremity
;
Lumbar Vertebrae
;
Male
;
Outcome Assessment (Health Care)
;
Prevalence
;
Treatment Outcome*
;
Visual Analog Scale
4.Radiologic Findings of Acute Spontaneous Subdural Hematomas.
Hyun Jung KIM ; Won Kyong BAE ; Jang Gyu CHA ; Gun Woo KIM ; Won Su CHO ; Il Young KIM ; Kyung Suk LEE
Journal of the Korean Radiological Society 1998;38(3):391-396
PURPOSE: To evaluate the characteristic CT and cerebral angiographic findings in patients with acutespontaneous subdural hematomas and correlate these imaging findings with causes of bleeding and clinical outcome. MATERIALS AND METHODS: Twenty-one patients with nontraumatic acute spontaneous subdural hematoma presentingduring the last five years underwent CT scanning and cerebral angiography was performed in twelve. To determinethe cause of bleeding, CT and angiographic findings were retrospectively analysed. Clinical history, laboratoryand operative findings, and final clinical outcome were reviewed. RESULTS: The 21 cases of acute spontaneoussubdural hematomas were caused by cerebral vascular abnormalities(n=10), infantile hemorrhagic disease(n=5), orwere of unknown origin(n=6). All ten cases of cerebral vascular abnormality were confirmed angiographically; sixwere aneurysms, three were arteriovenous malformations, and one was moyamoya disease. On CT, subarachnoidhemorrhage was seen to be associated with aneurysms, intracerebral hemorrhage with arteriovenous malformations,and intraventricular hemorrhage with moyamoya disease. All five patients with hemorrhagic disease were infantsaged 1-17 months ; characteristic diffuse distribution of subdural hematoma in both temporoparietal-occipitalregions is typical. The average overall mortality rate was 52.4%(11/21). In patients with cerebral vascularabnormalities, mortality was as low as 20%(2/10), but in hemorrhagic disease was high (60%). In cases of unknownorigin it was 100%. CONCLUSION: Acute spontaneous subdural hematoma is a rare condition, and the mortality rateis high. In patients with acute spontaneous subdural hematoma, as seen on CT, associated subarachnoid orintracerebral hemorrhage is strongly indicative of intracerebral vascular abnormalities such as aneurysm andarteriovenous malformation, and cerebral angiography is necessary. To ensure proper treatment and thus morkedlyreduce mortality, the causes of bleeding should be prompty determined by means of cerebral angiography.
Aneurysm
;
Arteriovenous Malformations
;
Cerebral Angiography
;
Cerebral Hemorrhage
;
Hematoma
;
Hematoma, Subdural*
;
Hemorrhage
;
Humans
;
Intracranial Aneurysm
;
Mortality
;
Moyamoya Disease
;
Retrospective Studies
;
Tomography, X-Ray Computed
5.A Prospective Randomized Clinical Trial Comparing Bone Union Rate Following Anterior Cervical Discectomy and Fusion Using a Polyetheretherketone Cage: Hydroxyapatite/B-Tricalcium Phosphate Mixture versus Hydroxyapatite/Demineralized Bone Matrix Mixture.
Jemin YI ; Gun Woo LEE ; Woo Dong NAM ; Kye Young HAN ; Myung Ho KIM ; Jong Won KANG ; Jonghwa WON ; Seong Wan KIM ; Won NOH ; Jin S YEOM
Asian Spine Journal 2015;9(1):30-38
STUDY DESIGN: Prospective randomized noninferiority trial. PURPOSE: To evaluate whether the union rate of anterior cervical discectomy and fusion (ACDF) using a polyetheretherketone (PEEK) cage filled with a mixture of hydroxyapatite (HA) and demineralized bone matrix (DBM) is inferior to that of a mixture of beta-tricalcium phosphate (beta-TCP) and HA. OVERVIEW OF LITERATURE: There have been no clinical trials investigating the outcomes of a mixture of HA and DBM in a PEEK cage in ACDF. METHODS: Eighty-five eligible patients were randomly assigned to group B (n=43), in which a PEEK cage with a mixture of HA and DBM was used, or group C (n=42), in which a PEEK cage with a mixture of HA and beta-TCP was used. The primary study endpoint was the fusion rate, which was assessed with dynamic radiographs and computed tomography (CT) scans. Secondary endpoints included pain intensity using a visual analogue scale, functional outcome using a neck disability index score, laboratory tests of inflammatory profiles, and the infection rate. RESULTS: Seventy-seven patients (38 in group B and 39 in group C) were included in the final analysis. One year postoperatively, bone fusion was achieved in 87% of group B patients and 87% of group C patients on dynamic radiographs, and 87% of group B patients and 72% of group C patients on CT scans (p=1.00 and 0.16, respectively). There were also no between-groups differences with respect to the secondary endpoints. CONCLUSIONS: A HA/DBM mixture inside a PEEK cage can provide noninferior outcomes compared to a HA/TCP mixture in ACDF.
Bone Matrix*
;
Diskectomy*
;
Durapatite
;
Humans
;
Hydroxyapatites
;
Neck
;
Prospective Studies*
;
Tomography, X-Ray Computed
6.Multiple Lumbar Intradural Dermoid Cysts without Spinal Dysraphism.
Gun Woo WON ; Sang Jin KIM ; Do Sang CHO ; Eui Kyo SEO
Journal of Korean Neurosurgical Society 2004;36(6):505-507
We report a rare case of lumbar intradural dermoid cysts. A 19 year-old male presented with low back pain for 3years. Physical examination revealed no abnormalities including skin lesions. On the magnetic resonance images, multiple intradural extramedullary cystic lesions were found in the lumbar region. These lesions were removed surgically. Histologically, the mass turned out to be a dermoid cyst. We think those were unusual intraspinal dermoid cysts because they were not associated with other congenital spinal malformation, and located in the intradural extramedullary region. We report this case of lumbar dermoid cysts with a review of literatures.
Dermoid Cyst*
;
Humans
;
Low Back Pain
;
Lumbosacral Region
;
Male
;
Physical Examination
;
Skin
;
Spinal Dysraphism*
;
Young Adult
7.A Serous Papillary Cystadenoma of Borderline Malignancy in Testis.
Hyun Jun PARK ; Sung Woo PARK ; Won Hee CHON ; Suk Gun JUNG ; Nam Cheol PARK
Korean Journal of Andrology 2007;25(1):36-38
Serous papillary cystadenomas arising in testis have been rarely reported, and they often resemble ovarian serous tumors of borderline malignancy. Herein, we report a case of a serous papillary cystadenoma of the testis in a 59 year old man. Based on a clinical diagnosis of left testicular tumor, a left radical orchiectomy was performed. The pathologic evaluation revealed a serous papillary cystadenoma of borderline malignancy in the testis.
Cystadenoma, Papillary*
;
Diagnosis
;
Humans
;
Middle Aged
;
Orchiectomy
;
Testis*
8.The Clinical Analysis of 100 cases of Coronary artery Bypass Grafting with the Right Gastroepiploic artery.
Hyun SONG ; Han Jung LIM ; Hyun Woo LEE ; Jong Pil JUNG ; Je Kyoun SHIN ; Jong Ook KIM ; Jong Bin PARK ; Jae Won LEE ; Meong Gun SONG
The Korean Journal of Thoracic and Cardiovascular Surgery 2000;33(8):638-642
BACKGROUND: In an effort t enhance long term patency of coronary bypass grafts, utilization of arterial conduits have been on an icrease. With the same objective, we have been using the right gastroepiploic artery (RGEA) in coronary artery bypass procedures since 1998. The current paper has been undertaken with the aim of assessing the apropriateness, problems, and short term results of using the RGEA as an arterial graft conduit by studying the postoperative clinical results of 100 patients than received coronary artery bypass grafting (CARG) with this artery. MATERIAL AND METHOD: Between May of 1998 and May of 1999, an analysis of the mortality, postoperative myocardial infarction, and the need for IABP insertion as a result of low cardiac output were made between 100 consecutive patients undergoing CABG with the RGEA. There was one postoperative death due to cerebral infarction. Postoperative complications/morbidity comprised myocardial infarction in 2, cerebral infarct in 3, reoperation due to bleeding in 1, mediastinitis in 1, and low cardiac output syndrome necessitating IABP in 3 patients. Complicatons related to harvesting of the arterial grafts were not experienced in any of the patients. CONCLUSION: The results of the current data show that utilization of the RGEA in CABG is not associated with increased mortality/morbidity and demonstrates satisfactory short term results suggesting the usefulnessof this conduit as an arterial graft.
Arteries
;
Cardiac Output, Low
;
Cerebral Infarction
;
Coronary Artery Bypass*
;
Coronary Vessels*
;
Gastroepiploic Artery*
;
Hemorrhage
;
Humans
;
Mediastinitis
;
Mortality
;
Myocardial Infarction
;
Reoperation
;
Transplants
9.The Efficacy of Scalene Injection in Thoracic Outlet Syndrome.
Gun Woo LEE ; Young Ho KWON ; Ju Ho JEONG ; Jung Won KIM
Journal of Korean Neurosurgical Society 2011;50(1):36-39
OBJECTIVE: To evaluate the efficacy of scalene injection in patients with thoracic outlet syndrome. METHODS: We selected 142 patients diagnosed with thoracic outlet syndrome between January 2005 and October 2009. We performed a series of scalene injection with conservative treatment in all cases. Patients rated their pain degrees using a visual analogue scale. We also evaluated the time to return to everyday life and work, and patients' functional capacity. RESULTS: There were no complications or instances of inadvertent somatic or sympathetic ganglionic blockade after scalene injection. Overall, 111 patients (76.5%) experienced improved symptoms after the first set of scalene injection and 128 patients (88.2%) improved after scalene injection followed by conservative treatment. Of the 68 patients who returned to work during the study period, 54 returned within 1 week, and 62 within 2 weeks. Of those who returned to work, 61 reported nearly full functional capacity. We found that scalene injection was more effective in cases of thoracic outlet syndrome related to trauma than in those related to work-related repetitive stress. CONCLUSION: In patients with thoracic outlet syndrome, scalene injection effectively reduces pain. We recommend scalene injection as an adjunct to conservative treatment.
Ganglia, Sympathetic
;
Humans
;
Thoracic Outlet Syndrome
10.Percutaneous Endoscopic Interlaminar Discectomy for L5-S1 Disc Herniation: Axillary Approach and Preliminary Results.
Seungcheol LEE ; Sang Ho LEE ; Won Chul CHOI ; Gun CHOI ; Song Woo SHIN ; Richard KAUL
Journal of Korean Neurosurgical Society 2006;40(2):79-83
OBJECTIVE: The purpose of this study was to describe a surgical technique of axillary approach of percutaneous endoscopic interlaminar discectomy for L5-S1 disc herniation and its preliminary results. METHODS: From July 2002 to September 2003, 101 patients with lumbar radiculopathy due to L5-S1 disc herniation, who were treated by percutaneous interlaminar endoscopic discectomy, were retrospectively reviewed. There were 57 males and 44 females with a mean age of 44.8 years (range, 18 to 62 years). The surgery consisted of needle insertion into the epidural space via the interlaminar space, sequential dilatation, and endoscopic discectomy through the axillary area of the S1 root. RESULTS: The mean follow-up period was 14.5 months and the average surgical time was 41 min. According to the modified Macnab criteria, 44 patients (43.6%) had excellent outcomes, 49 (48.5%) had good results and only 8 (7.8%) had fair or poor outcomes. Four patients had a revision microdiscectomy due to incomplete removal of disc fragment. There were no major complications related to this surgical approach. CONCLUSION: Axillary approach of percutaneous endoscopic interlaminar discectomy is safe and effective procedure for the treatment of L5-S1 disc herniation. It combines the advantages of MED and conventional percutaneous endoscopic discectomy.
Dilatation
;
Diskectomy*
;
Epidural Space
;
Female
;
Follow-Up Studies
;
Humans
;
Male
;
Needles
;
Operative Time
;
Radiculopathy
;
Retrospective Studies