1.A study of diphenylcyclopropenone contact sensitization.
Kuk Hyeong LEE ; Do Won KIM ; Gun Yeon NA ; Jum Young KIM ; Ki Suk SUH
Korean Journal of Dermatology 1991;29(3):292-297
No abstract available.
Dermatitis, Atopic
;
Pyroglyphidae
2.Plasma Cell Leukemia Having Pseudopods: A Case Report.
Nam Hee RYU ; Sang Gyung KIM ; Chang Ho JEON ; Hun Suk SUH ; Dong Gun SHIN
Korean Journal of Clinical Pathology 1997;17(4):547-552
Plasma col1 leukemia with motility-related morphological behavior is rarely studied. The plasma cells have variable degrees of cytoplasmic morphologies as dairy Projections, long extensions and pseudopods. These morphological evidences show the papa bility of wide spread and dissemination of disease itself. We present a case of a 38 year old woman who had back pain for 4 months and was diagnosed as a solitary plasmacytoma of the third lumbar vertebra. In spite of resection of the tumor and chemotherapy, the plasmacytoma was disseminated into both breasts and ovaries within less than a year. On her blood examination, we counted 34% of plasma cells in peripheral blood and 91.6% of plasma cells in bone marrow aspiration. Most of them resealed hairy projections and pseudopods of the cytoplasm.
Adult
;
Back Pain
;
Bone Marrow
;
Breast
;
Cytoplasm
;
Drug Therapy
;
Female
;
Humans
;
Leukemia
;
Leukemia, Plasma Cell*
;
Ovary
;
Plasma Cells*
;
Plasma*
;
Plasmacytoma
;
Spine
3.The Effect of Education in Reducing Catheter-related Urinary Tract Infections in Intensive Care Units at a University Hospital.
Yun Jung CHANG ; Kyung A CHOI ; Hyun Kyung LEE ; Yeong Suk JIN ; Park Gun MIN ; Jin Young OH ; Eu Suk KIM
Korean Journal of Nosocomial Infection Control 2008;13(2):90-96
BACKGROUND: Urinary tract infections (UTIs) are the most frequent nosocomial infections and are frequently associated with indwelling urinary catheters. It is known that adherence to standard infection control measures for urinary catheters can reduce UTIs in hospitals. This study was performed to evaluate the effect of education in reducing catheter-related UTIs (CR-UTIs) in intensive care units (ICUs) of a university hospital. METHODS: CR-UTIs were prospectively monitored for all patients with indwelling urinary catheters in ICUs from July 2006 through December 2007. Recommendations based on previously known guidelines for catheter insertion, catheter management, and specimen collection to prevent CR-UTIs were formulated and educated in March 2007. Knowledge and adherence level were evaluated before and after educating healthcare workers about the recommendations using questionnaire. Changes in knowledge and adherence level before and after education were compared by Chi-square test. Changes in the rate of CR-UTIs and urinary catheter utilization ratios were also analyzed by Fisher's exact test. RESULTS: After education, knowledge level of and adherence level to most of the recommendations were improved significantly. The rate of CR-UTIs significantly decreased by 48% from 7.43/1,000 catheter-days before intervention to 3.87/1,000 catheter-days after intervention (P=0.02). CONCLUSION: Surveillance for nosocomial infections and education for standard infection control measures are very important in preventing CR-UTIs in ICUs.
Catheters
;
Cross Infection
;
Delivery of Health Care
;
Humans
;
Infection Control
;
Critical Care
;
Intensive Care Units
;
Prospective Studies
;
Specimen Handling
;
Urinary Catheterization
;
Urinary Catheters
;
Urinary Tract
;
Urinary Tract Infections
;
Surveys and Questionnaires
4.Glycated Hemoglobin and All-Cause Mortality in Korean Type 2 Diabetes
Mi Suk AN ; Sun A KIM ; Jun Ho LEE ; Seong Woo CHOI ; Min Ho SHIN
Chonnam Medical Journal 2017;53(3):223-228
The purpose of this study was to evaluate the association between glycated hemoglobin (HbA1c) and all-cause mortality in type 2 diabetes mellitus. We conducted a community-based prospective cohort study of 352 type 2 diabetic patients aged 30-92 who participated in a community diabetes complications screening program in Gokseng-gun, Jeollanamdo, Korea. HbA1c levels were categorized as <6.5%, 6.5-6.9%, 7.0-7.9%, 8.0-8.9% and ≥9.0%. Patients were followed up on for a mean of 6.9 years. The Cox proportional hazards model was used to evaluate the relationship between HbA1c levels and all-cause mortality. During the mean follow-up period of 6.9 years, 77 patients (21.9%) died. A J-shaped association was found between HbA1c and all-cause mortality, with the lowest mortality at 6.5-6.9% of HbA1c levels. Compared to patients with HbA1c of 6.5-6.9%, patients with <6.5%, 7.0-7.9%, 8.0-8.9% and ≥9.0% had an adjusted hazard ratio (95% confidence interval) for all-cause mortality of 1.71 (0.76-3.84), 1.23 (0.53-2.82), 1.32(0.51-3.44) and 2.66 (1.01-7.02), respectively. We found a J-shaped association between glycated hemoglobin and all-cause mortality in Korean type 2 diabetic patients.
Cohort Studies
;
Diabetes Complications
;
Diabetes Mellitus
;
Diabetes Mellitus, Type 2
;
Follow-Up Studies
;
Hemoglobin A, Glycosylated
;
Humans
;
Jeollanam-do
;
Korea
;
Mass Screening
;
Mortality
;
Proportional Hazards Models
;
Prospective Studies
5.Molecular Epidemiology and Risk Factors of Staphylococcus epidermidis Isolated from Patients with Acute Leukemia.
Kyung Mi KIM ; Dong Gun LEE ; Sang Il KIM ; Jung Hyun CHOI ; Sung Suk HAN ; Wan Shik SHIN
Korean Journal of Nosocomial Infection Control 2003;8(2):71-82
BACKGROUND: The purpose of this study is to define the risk factors of S. epidermidis acquisition and the epidemiology of strain variation in acute leukemia patients. METHODS: The participants were 155 patients of acute leukemia admitted in a University hospital for 11 months. 83 patients are the isolated group who had isolated S. epidermidis from body sites (blood, oral cavity, nares, rectum) and 72 patients are the not isolated group who had not isolated S. epidermidis. Isolates were analysed by CHEF and cluster analysis with dendrogram. Differences In proportions were tested with the Chi-square and Fisher's exact test. RESULTS: Ninety-one S. epidermidis were obtained from blood, oral cavity, nares, and rectum. The major proportion of positive culture was 81.3% from nares. Eight-nine S. epidermidis were isolated from healthcare workers. There were significant development of bacteremia in patients with S. epidermidis from nares. Resistance rate of S. epidermidis was 75.8% to methicillin, 86.3% to erythromycin, 81.l% to gentamicin, 68.9% to ciprofloxacin, 0% on vancomycin. There was significant difference on resistance rate between patients and healthcare workers' group. There was no relation between the strain of patients and those of healthcare workers. Sex age, diagnosis, length of stay, type of chemotherapy, duration of chemotherapy, Type of central venous catheter. duration of central venous catheter, prior antibiotic therapy, number of antibiotics, site of nosocomial infection, neutropenic period were not significantly different between S. epidermidis isolated group and not isolated group. Significant risk factors included duration of central venous catheter. hyper-alimentation, and folliculitis. CONCLUSION: Our result suggests that S. epidermidis in nares can be a risk factor of bacteremia. This research would be helpful for decreasing the S. epidermidis of immunocompromised patients.
Anti-Bacterial Agents
;
Bacteremia
;
Central Venous Catheters
;
Ciprofloxacin
;
Cross Infection
;
Delivery of Health Care
;
Diagnosis
;
Drug Therapy
;
Epidemiology
;
Erythromycin
;
Folliculitis
;
Gentamicins
;
Humans
;
Immunocompromised Host
;
Length of Stay
;
Leukemia*
;
Methicillin
;
Molecular Epidemiology*
;
Mouth
;
Rectum
;
Risk Factors*
;
Staphylococcus epidermidis*
;
Staphylococcus*
;
Vancomycin
6.The Clinical Effect of Recombinant Human Granulocyte-Colony Stimulating Factor to the Leukopenia During Chemotherapy in the Patients with Gynecologic Malignancies.
In Suk CHOI ; Jung Mi SON ; Hyun KIM ; Gun Sang YOO ; jun Mo AN ; Won Gue KIM ; Un Dong PARK
Korean Journal of Gynecologic Oncology and Colposcopy 1996;7(2):100-109
An increase in the dose of chemotherapy enhances the response of many experimental and clinical cancers, but the extent of chemotherapy dose escalation and repeated use is often limited by myelosuppression. The side effects of chemotherapy including bleeding and infection due to myelosuppression have resulted in delayed therapy and a reduction in the therapeutic dose, therefore it is necessary to overcome myelosuppression especially leukopenia in patients with gynecologic malignancies who recieved chemotherapy. This study is undertaken to investigate the clinical effects of rhG-CSF(recombinant human Granulocyte-colony stimulating factor) in 29 patients with gynecologic malignancy who recieved chemotherapy. It was given at a dose of 100 microgram bid/day subcutaneously until significantly increase of leukocyte count in leukopenic patient. The results showed, the rhG-CSF has significantly increased the number and function of leukocyte. The use of rhG-CSF was effective and useful to treat chemotherapy induced leukopenia and to accelerate the recovery from this complications.
Drug Therapy*
;
Hemorrhage
;
Humans*
;
Leukocyte Count
;
Leukocytes
;
Leukopenia*
8.RECONSTRUCTION WITH METAL PLATE AND ILIAC BONE GRAFT ON AMELOBLASTOMA.
Young Rae MAENG ; In Suk KIM ; Sung Soo SHIN ; Gee Jeong UM ; Sang Hun PARK ; Jun woo PARK ; Gun Joo RHEE
Journal of the Korean Association of Oral and Maxillofacial Surgeons 1997;23(4):749-755
This is to report a case of immediate reconstruction after hemimandibulectomy by using of bicorticocancellous block bone harvested from the iliac crest in the case of an ameloblastomaon the mandible. Because the lesion involved condylar area, it was reconstructed with titanium artificial condyle attached to A/O metal plate. Three weeks after the operation, infection developed with suppuration and was well treated with adequate antibiotic therapy and drainage. The patient has been followed up over a four-year period and taken an orthopantomogram every three or six month for the examination of mandibular movement, the potentiality of recurrence and the remodeling of the grafted bone. At present, the patient is satisfied with her appearence and has a normal occlusion with proper masticatory function, and there is no sign of recurrence.
Ameloblastoma*
;
Drainage
;
Humans
;
Mandible
;
Mandibular Osteotomy
;
Recurrence
;
Suppuration
;
Titanium
;
Transplants*
9.Complete Repair of Coarctation of the Aorta and a Ventricular Septal Defect in a Low Birth Weight Neonate.
Jae Gun KWAK ; Jae Hyun JUN ; Jae Suk YOO ; Woong Han KIM
The Korean Journal of Thoracic and Cardiovascular Surgery 2008;41(4):480-483
Even though some authors have reported on the advantages of early total correction of complex heart disease, for low birth weight premature neonates, most surgeons prefer a multi-step approach to early total correction due to the many problems, such as the technical problems, the cardiopulmonary bypass management and etc. We report here on a successful case of early one-stage total repair of coarctation of the aorta and a ventricular septal defect in a 1,250 gram premature neonate.
Aortic Coarctation
;
Cardiopulmonary Bypass
;
Heart Diseases
;
Heart Septal Defects, Ventricular
;
Humans
;
Infant, Low Birth Weight
;
Infant, Newborn
;
Infant, Premature
;
Thoracic Surgery
10.A Valid Indication and the Effect of Bilateral Inferior Oblique Transposition on Recurrent or Consecutive Horizontal Deviation in Infantile Strabismus.
Suk Gyu HA ; Gun Hoo NA ; Seung Hyun KIM
Korean Journal of Ophthalmology 2017;31(2):138-142
PURPOSE: To evaluate the effects of bilateral inferior oblique transposition (BIOT) on horizontal deviation from primary position among patients with bilateral dissociated vertical deviation (DVD) associated with inferior oblique overaction (IOOA) in infantile strabismus. METHODS: Retrospective chart review was conducted among 19 patients with infantile strabismus. All patients had DVD and IOOA with consecutive or recurrent horizontal deviation and underwent modified BIOT surgery. Patients were divided into three subgroups: patients who underwent BIOT (BIOT group, n = 9) alone, BIOT with medial rectus recession or lateral rectus resection simultaneously (ET BIOT group, n = 6), or BIOT with lateral rectus recession or medial rectus resection simultaneously (XT BIOT group, n = 4). Postoperative angle of horizontal deviation (prism diopter, PD) and corrected magnitude of horizontal deviation (PD) at final visit after surgery were analyzed in each group. RESULTS: The mean age was 55.11 ± 21.05 months (range, 32 to 115). The mean follow-up period was 8.68 ± 2.87 months (range, 6 to 18). Preoperative horizontal deviation was 4.23 ± 5.99 PD (range, 0 to 16) in BIOT, −17.33 ± 6.76 PD (range, −30 to −10) in ET BIOT, and 17.50 ± 2.52 PD (range, 14 to 20) in XT BIOT. Esodeviation is represented by negative values. DVD and IOOA were reduced less than +1 in all patients. The corrected amount of horizontal deviation was 3.56 ± 5.18 PD (range, 0 to 16) in BIOT surgery alone and larger in XT BIOT (18.50 ± 3.41 PD) than in ET BIOT (12.33 ± 5.57 PD, p = 0.004). CONCLUSIONS: Minimal exodeviation was corrected by BIOT alone. In addition, secondary eso- or exodeviation at great magnitudes should be corrected with proper horizontal muscle surgery along with BIOT.
Esotropia
;
Exotropia
;
Follow-Up Studies
;
Humans
;
Retrospective Studies
;
Strabismus*