1.A Case of Chlamydia trachomatis Peritonitis Mimicking Tuberculous Peritonitis.
Hwa Mi KANG ; Tae Hoon OH ; Gun Hi KANG ; Tae Joo JOEN ; Dong Dae SEO ; Won Chang SHIN ; Won Choong CHOI ; Keun Ho YANG
The Korean Journal of Gastroenterology 2011;58(2):111-116
Lymphocytic ascites with low serum-ascites albumin gradient (SAAG) are observed mainly in tuberculous peritonitis, peritoneal carcinomatosis, and pancreatic disease. However, pelvic inflammatory disease (PID) induced generalized peritonitis causing diffuse ascites has been rarely described. We report a 26-year old female patient, who was diagnosed as generalized peritonitis with diffuse ascites due to Chlamydia trachomatis infection. Gynecologic examination did not show the clue of PID and in the analysis of ascites, low SAAG, predominant lymphocyte count and high level of adenosine deaminase were noted. Although the best impression was tuberculous peritonitis on the base of these findings, the laparoscopic finding was consistent with PID and the PCR for C. trachomatis infection in cervical swab was positive. This case suggests that C. trachomatis peritonitis should be considered as a rare cause of low SAAG and lymphocytic ascites in sexually active women and should be intensively evaluated including laparoscopic examination.
Adult
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Anti-Bacterial Agents/therapeutic use
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Ascites/diagnosis/metabolism/therapy
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Ascitic Fluid/chemistry
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Cephalosporins/therapeutic use
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Chlamydia Infections/complications/*diagnosis/drug therapy
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Chlamydia trachomatis/genetics/*isolation & purification
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Diagnosis, Differential
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Female
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Humans
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Laparoscopy
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Peritonitis/*diagnosis/etiology/radiography
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Peritonitis, Tuberculous/diagnosis
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Serum Albumin/metabolism
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Tomography, X-Ray Computed
2.Ileal Stenosis Occurred 3 Months after Blunt Abdominal Trauma.
Gun Hi KANG ; Tae Joo JEON ; Dong Dae SEO ; Tae Hoon OH ; Soohyun KIM ; Hyun Sun CHO ; Byung Noe BAE ; Jung Yeon KIM
The Korean Journal of Gastroenterology 2011;57(6):370-373
We present a case of ileal stenosis with delayed presentation 3 months after car accident. Ileal stenosis after blunt abdominal trauma is a rare clinical entity. We present CT and small bowel series 3 months after trauma. Image showed segmental thickening of intestinal wall and proximal bowel dilation. At surgery, a stenotic bowel loop was adjacent to a fibrotic mesentery. Histological examination showed ulcers, inflammatory cells and fibroblasts infiltrated to the muscularis mucosae, submucosa, and mesentery. The most likely cause, supported by most authors, implicates an injury to the mesentery. Post-traumatic ischemic bowel stenosis may result from even small tears and contusions of mesentery. Posttraumatic intestinal stenosis should be included in the differential diagnosis in a patient with a history of blunt abdominal trauma and signs of intestinal obstruction.
3.Massive Pulmonary Thromboembolism Associated With Renal Vein Thrombosis While Using Oral Contraceptives.
Gun Hi KANG ; Seung Gu KIM ; Hye Young LEE ; Jun Jae KIM ; Hyun PARK ; Na Na BAIK ; Young Sup BYUN ; Byoung Kwon LEE
Korean Circulation Journal 2008;38(11):618-621
Pulmonary thromboembolism (PTE) originating from a renal vein thrombosis (RVT) is very rare, especially in relatively healthy young women. The patient described herein presented with a syncope-associated massive PTE. She was previously healthy, except for termination of an ectopic pregnancy with methotrexate 4 months before. The only medication she was taking was an oral contraceptive (OC), which was started 3 months before the PTE. She had no family history of venous thromboembolism (VTE) or any other underlying risk factors. We report the case of a woman who had a PTE originating from a RVT associated with OC use after an ectopic pregnancy.
Contraceptives, Oral
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Female
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Humans
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Methotrexate
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Pregnancy
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Pregnancy, Ectopic
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Pulmonary Embolism
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Renal Veins
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Risk Factors
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Thrombosis
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Venous Thromboembolism
4.A Phase II Trial of Paclitaxel, 5-fluorouracil (5-FU) and Cisplatin in Patients with Metastatic or Recurrent Gastric Cancer.
Gun Hi KANG ; Gwang Sil KIM ; Hyo Rak LEE ; Young Jin YUH ; Sung Rok KIM
Cancer Research and Treatment 2008;40(3):106-110
PURPOSE: We wanted to assess the effectiveness and safety of combination chemotherapy with paclitaxel, 5-fluorouracil (5-FU) and cisplatin for treating advanced gastric cancer. MATERIALS AND METHODS: Patients with metastatic or recurrent gastric cancer were entered into this study. Paclitaxel at a dose of 135 mg/m2 on day 1, 5-FU 1 g/m2/ day in a 24 hour continuous infusion from day 1 to day 4 and cisplatin 60 mg/m2 on day 1 were administered. This regimen was repeated every 3 weeks. RESULTS: A total of 34 patients were enrolled in this study. Among them, 33 patients were finally evaluable for their response. 17 (51.5%) patients had a partial response (95% CI: 26.0~77.0%). The median duration of overall survival was 13.2 months. Grade 3 or 4 neutropenia and thrombocytopenia were observed in 15.2% and 1.1% of all the cycles, respectively. Grade 3 stomatitis and neurotoxicity were observed in 20.6% and 1.1% of all patients, respectively. Grade 4 non-hematologic toxicity was not observed. CONCLUSIONS: The regimen of paclitaxel, 5-FU and cisplatin demonstrated activity and accepatable toxicity for treating metastatic gastric cancer.
Cisplatin
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Drug Therapy, Combination
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Fluorouracil
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Humans
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Neutropenia
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Paclitaxel
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Stomach Neoplasms
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Stomatitis
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Thrombocytopenia
5.A Case of Recurrent Pneumonitis Caused by Bojungikgitang(Bu-Zhong-Yi-Qi-Tang).
Seung Gu KIM ; Gun Hi KANG ; Jun Jae KIM ; Hyun PARK ; Na Na BAEK ; Sang Bong CHOI ; Eun Ah SHIN ; Joung Sook KIM ; I Nae PARK ; Hoon JEUNG ; Jin Won HUR ; Sung Soon LEE ; Hyun Kyung LEE ; Joo In KIM ; Young Min LEE ; Hyuk Pyo LEE ; Ho Kee YUM ; Soo Jeon CHOI
Tuberculosis and Respiratory Diseases 2008;65(5):416-420
Many classes of drug, such as antineoplastic drugs and antiarrhythmic drugs, have potential to induce interstitial lung disease. Herbal medicines are also believed to have the potential to induce pneumonitis. However, to our knowledge, there are no reports of pneumonitis caused by herbal medications in the Korean medical database. We report a case of recurrent pneumonitis caused by a self rechallenge of the Herbal medicine Bojungikgitang (Bu-Zhong-Yi-Qi-Tang : Hochu-ekki-to).
Anti-Arrhythmia Agents
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Antineoplastic Agents
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Herbal Medicine
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Lung Diseases, Interstitial
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Pneumonia
6.A Case of Primary Biliary Cirrhosis in Association with Sjorgen's Syndrome Developing Features of Systemic Lupus Erythematosus.
Chang Gyo LEE ; Hyun Kyu CHANG ; Seung Yong KIM ; Ho Hyung KANG ; Duk Jae KIM ; Chin Kun CHANG ; Ju Hi MAENG ; Hui Sup LEE ; Pae Gun PARK ; Jae Gul CHUNG
The Journal of the Korean Rheumatism Association 2001;8(1):59-63
Primary biliary cirrhosis (PBC)is a chronic inflammatory disease characterized by fibrous obliteration of intrahepatic bile ductules.Although the etiopathogenesis of PBC remains unclear,several studies suggest that a disordered immune response may be involved.This disease is commonly associated with various autoimmune diseases,such as Sjogren's syndrome,scleroderma, rheumatoid arthritis,Hashimoto's thyroiditis,polymyositis,and pernicious anemia.More than 80%of cases with PBC are accompanied by at least one autoimmune disorder,and 40%by two or more. Sjogren's syndrome,defined by dry eyes and xerostomia,may be found in 69 to 81%of PBC patients. However, concurrent coexistence of PBC and systemic lupus erythematosus (SLE)has been rarely described in the literature.We report a 46-year-old female with PBC and Sjogren's syndrome who also satisfied a classification criteria of SLE.
Bile
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Classification
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Female
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Humans
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Liver Cirrhosis, Biliary*
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Lupus Erythematosus, Systemic*
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Middle Aged
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Sjogren's Syndrome