Objective To observe the protective effect of Racecadotril combined with Succinate Injection on myocardial injury in children with rotavirus enteritis and explore its clinical significance.Methods Totally 116 cases of children with rotavirus enteritis from Huangshi Traditional Chinese Medicine ofEdong Healthcare Group were selected in this study.Patients were randomly divided into Racecadotril control group (n =58) and Racecadotril combined with Succinate Injection observation group (n =58).The levels of CK,CK-MB,LDH,IL-17,IL-6,and TNF-α were detected by ELISA analysis.The rates of clinic effects and adverse reaction were compared.Results There was no significant difference of CK,CK-MB,LDH,IL-17,IL-6,and TNF-α between two groups before treatment.After treatment,they were all decreased in two groups (P ＜ 0.05,0.01).However,they were all lower in observation group than those in control group after treatment (P＜0.05).The rate of clinic effects was 94.8％ in observation group,which was higher than 81.0％ in control group (P ＜ 0.05).The rate of adverse reaction was 8.6％ in observation group and 6.9％ in control group.There was no significant difference between two groups.Conclusion Racecadotril combined with Succinate Injection inhibits the inflammatory response to protect myocardial injury in RVE children,with significantly clinical efficacy and safety.

In the treatment of 34 cases of radial nerve paralysisby puncturing the acupoints in Yangming meridians of the hand and foot, plus TDP radiation in the local areas after acupuncture, the total effective rate is 97.1%.

Objective To explore the psychological characteristics of cancer long-term survivors.Methods One hundred and fifty one cancer long-term survivors(survival time ≥5 years) were chosen for participation from Guangzhou and Shenzhen by the coin method in this study.The qualitative data of the patients'psychological characteristics were collected by individual interviews,and the patients'behavioral and psychological characteristics were measured by the Tumor Psychological Scale(TPS),the Cancer Coping Modes Questionnaire(CCMQ) and the Psychological Adjustment Scale for Cancer Patients(PASCP).The psychological characteristics of the 151 cancer long-term survivors were compared with the average level of cancer patients (over 557 patients).Quantitive data were analyzed by two independent samples't-test.Results (1) Most cancer long-term survivors knew their diagnosis in two weeks after they were diagnosed.The cancer long-term survivors were better in mentality and got more social supports.Most long-time survivors attributed their success to good psychological well-being and positive treatments.(2) The TPS scores of cancer long-term survivors group(1.99 ± 0.45,1.68 ± 0.51,1.33 ± 0.32,1.87 ± 0.44,1.78 ± 0.41 respectively) were lower than the scores of the average level of cancer patients (3.06 ±2.12,3.08 ± 2.03,2.86 ± 2.08,3.02 ± 2.06,2.98 ± 1.75 respectively) in the dimensions of personality,emotion,unconscious,cognition and the total average score.The differences were significant statistically(P ＜ 0.01).The CCMQ scores of cancer long-term survivors group were higher than the scores of the average level of cancer patients in the dimension of confrontation and catharses.In the dimensions of avoidance and suppression,resignation and fantasy,the scores of cancer long-term survivors group were lower than the scores of the average level of cancer patients.All the differences were significant statistically (P ＜ 0.05).The PASCP scores of cancer long-term survivors group were higher than the scores of the average level of cancer patients in the dimension of emotion/self-esteem,subjective feeling,interpersonal relationship/social life,the daily life and the other.The differences was significant statistically(P＜ 0.001).Conclusion There are common characteristics of cancer long-term survivors such as good mental health state,lower tumor psychological level,positive coping styles,getting better psychological adjustment.

To design an inpatient charging management system to optimize the patient accounting flow. The problems in all links were analyzed, and auditing mode and flow were modified. Under the existing HIS, the sys-tem was developed with added datasheets, determined elements, desired rules, .Net framework and C# language. The system made the prescription linked with the charging so that the doubtful items could be marked automatically. The system facilitates the fee auditing, shortens the waiting time of the patient, enhances the communication between the departments and promotes the quality of medical records.

Objective To study effects of temperature on learning and memory of Drosophila melanogaster.Methods Food was put in two centrifuge tubes.Drosophila can smell and eat food through pores in one centrifuge tube but Drosophila can only smell but not eat food through pores in another centrifuge tube with obstacle.After Drosophila were bred at different temperatures,the variation of the numbers of Drosophila in two tubes were observed.Results The number of Drosophila bred at high temperature entering the tube and eating the food was fewer than that at normal temperature and low temperature.Conclusion High temperature can decrease the learning and memory behavior of Drosophila.

Objective:To develop and evaluate the Cancer Dangerous Factor and Aura Manifestation List(CDFAML).Methods:A self-report questionnaire was developed.A total of 639 cancer patients were asked to complete the questionnaire and evaluate the importance of each item.And 129 relatives and 103 doctors and nurses were also asked to evaluate the importance of each item.706 healthy people whose demographics were similar to the patients were asked to complete the list.Results:①CDFAML was finally refined as a list with 19-item;the 4 dimensions including somatic,psychological,social factor and life habits.②The list had good construct validity and could well reflect the dangerous factor and aura manifestation of the onset of cancer.The 4 dimensions and the total score of the patients were significantly different from healthy people's scores.③ The test-retest coefficients for the 4 dimensions and the total score were 0.82,0.76,0.80,0.77 and 0.83 respectively;Cronbach ? was 0.76,0.79,0.83,0.80 and 0.86 respectively.The split-half reliability of the questionnaire was 0.90.Conclusion:CDFAML has high validity,reliability.

Objective To study and contruct competency characteristic evaluation models of nursing supervisors in secondly hospitals.Methods Using the matron semi-structured interviews,literature review,questionnaire survey and expert questionnaires to discuss the competency of nursing supervisors in secodary hospitals.Results We found that the competency model of nursing supervisors in secondary hospitals could better reflect the competency of nursing supervisors.The model had 16 competencies which included knewleage skills.management and individual characters.Conclusions Through the study of the model of competency nursing supervisors in secondary hospitals,we form a set of standard for nursing supervisor selection based on their competency.The standard can help to select the most suited nursing supervisors who have great potentials.

Objective:To optimize and improve the content determination method for nitroglycerin ointment. Methods:An HPLC method was used,the column was Hypersil ODS(150 mm × 4. 6 mm,5 μm),the mobile phase was acetonitrile ∶water(50 ∶50),the detection wavelength was set at 220 nm,the flow rate was 1 ml·min-1 ,the column temperature was 30℃,and the injection volume was 20 μl. Results: The results showed a good linear relationship within the concentration range of 0. 020 3-0. 203 3 mg · ml-1 ( r =0. 999 9),and the average recovery was 99. 51%(RSD=1. 06%,n=9). Conclusion: The method is rapid,accurate and reproduci-ble,and can be used to determine the content of nitroglycerin in nitroglycerin ointment.

Aim To study the biotransformation of gly-cyrrhizin in rat intestine-liver. Methods The in situ vascularly perfused rat intestine-liver model was estab-lished with a validated LC-MS/MS method for assay of the model perfusate glycyrrhizin and glycyrrhetinic acid. Results The steady state intestinal and liver ex-traction ratios in the once-through perfused rat intes-tine-liver model for glycyrrhizin were ( 4. 2 ± 0. 6 )%and (28. 0 ± 3. 0)%, respectively; the first-order ab-sorption rate constant for glycyrrhizin in the recircula-tion of perfusate to the intestine model was ( 0. 33 ± 0. 06 ) min-1;after intraduodenal administration of gly-cyrrhizin,the main active metabolite in was the perfu-sate glycyrrhetinic acid, which was also found in intes-tinal luminal fluids. Conclusions The first-pass effi-cacy of glycyrrhizin is obvious and there is only a small amount of metabolite in the intestinal mucosa cells;gly-cyrrhizin is metabolized by gut bacteria or liver cells af-ter oral administration;the in situ vascularly perfused rat intestine-liver model can be used in glycyrrhizin pharmacokinetic studies.