Objective To explore the clinical efficacy of Ebastine joint Compound Glycyrrhizin in treatment of acute and chronic urticarial, and its effect on serum IgE levels.Methods Eighty cases of a-cute and chronic urticaria patients were collected from January 2010 to June 2014 in our hospital for treat-ment.They were randomly divided into control group and observation group, 40 cases in each group, the patients in the control group oral ebastine 10mg 1 times /day, patients in the observation group were given Compound Glycyrrhizin on 75mg and oral ebastine 10mg, 1 times /d, acute urticaria patients were treated for one week of continuous treatment, patients with chronic urticaria were treated for 4 weeks in a row;IgE level was measured by ELISA.Results After treatment, effective rate of patients with acute urticaria was 94.44%in the observation group, the control group was 68.42%; patients with chronic urticaria observa-tion group was 95.45%, the control group was 71.43%, a significant difference ( P <0.05 ) between the observation group and control group.IgE levels in both groups after treatment were reduced compared with before treatment ( P <0.01), after treatment IgE levels of patients had higher degree of improvement in the observation group, differences were statistically significant ( P <0.05).Conclusions The clinical effica-cy of ebastine joint Compound Glycyrrhizin on treatment of acute and chronic urticaria are better than single ebastine, two drugs used in conjunction with synergistic effect by regulating the body's immune function, re-duce allergy strength, improve efficacy.

Objective To describe and analyze the current situation of the four same type of departments in an hospital in order to provide a reference for the construction of"the most cost-effective medical care".Methods The CN-DRG were used to automatically group and compare the medical capacity and inpatient service efficiency of the hospital department groups,and in the refined analysis,one DRG disease group of in situ cancer and non-malignant disease loss uterine surgery and single species uterine fibroid was included,and the Kruskal-Wallis H test was used to further compare the differences in length of stay and various costs.Results It included a total of 22630 patients,whose weights varied from a maximum of 3948.62 in diagnostic group 1 to a minimum of 133.55 in diagnostic group 11.The cost consumption indexes ranged from a minimum of 0.89 in diagnostic group 5 to a maximum of 1.04 in diagnostic group 2,while the time consumption indexes ranged from a minimum of 0.48 in diagnostic group 11 to a maximum of 0.81 in diagnostic group 5.When comparing the diagnostic groups,there were statistically significant differences(P＜0.05)in hospitalization days,total cost,diagnostic cost,therapeutic cost,and cost of supplies.Specifically,when comparing the diagnostic and treatment groups within departments,the differences in hospitalization days and all costs were statistically significant(P＜0.05)in departments 1 and 2,the differences in diagnostic cost,therapeutic cost,and cost of supplies were statistically significant(P＜0.05)in department 3.Conclusion There exists a notable disparity in the extent to which each diagnostic and treatment group contributes to the hospital's service capacity and cost variability.Consequently,it is necessary to reasonably evaluate the length of hospital stay and medical cost of patients to achieve the highest cost-effective medical treatment.