1.Effects of Ulinastatin on Renal Apoptosis and Expression of bcl-2 in Rats with Severe Acute Pancreatitis
Yongjing ZHUANG ; Yongyang YU ; Guirong WU
Chinese Journal of Bases and Clinics in General Surgery 2003;0(06):-
Objective To explore the effects of ulinastatin(UTI) on renal apoptosis and expression of bcl-2 in rats with severe acute pancreatitis(SAP).Methods Sixty rats weighing 250-300 g were randomized divided into 3 groups:pseudo-operation group(SO group,n=20),SAP group(n=20) and UTI treated group(UTI group,n=20).The model of SAP was established by retrograde injection of 5% sodium taurocholate solution into the biliopancreatic duct in the rats.Serum Cr and BUN were determined.The left kidneys were resected for light and electronic microscopic study.Renal cell apoptosis was determined by TUNEL.Expression of bcl-2 was detected by immunohistochemical staining of SABC.Results Serum Cr,BUN,renal cell apoptotic index and bcl-2 expression were markedly increased in SAP group compared with SO group(P
2.Effect of cervical injected Phloroglucinol on the progress of labor during latent phase
Xia WU ; Guirong ZHAI ; Xinghua HUANG
Chinese Journal of Perinatal Medicine 1998;0(03):-
Objective To observe the effects of phlorohlucinol on cervical dilatation. Methods Totaling 250 normal parturients were randomized into four study groups (50 in each group) and control group (n=50). Phloroglucinol was given in the study groups(group1,2,3 and 4)at the dose of 40 mg to the cervix and/or 160 mg and 200 mg intravenously during the latent phase. The control group (group1) received only atropine (0.5 mg) intravenously. Results The overall speed of cervical dilatation in the study group was (2.82?1.82) cm/h and (1.78?1.01) cm/h in the control group. The mean time of the first stage of labor was (14.23?1.11) h and (17.71?2.23) h in the study and control group, respectively (P
3.Appropriate time for 50 g oral glucose challenge test (50 g GCT) during pregnancy
Xia WU ; Guirong ZHAI ; Xinghua HUANG
Chinese Journal of Perinatal Medicine 2003;0(05):-
Objective To evaluate the different effect of 50 g glucose challenge test (GCT) on screening the glucose intolerance at different gestational age. Methods Two thousand pregnant women were divided into 2 groups(1000 in each). Women in group A received 50 g GCT at 14 and 28 gestational weeks respectively and 75 g oral glucose tolerance test (OGTT) were performed in those cases with abnormal 50 g GCT. 50 g GCT was performed after fasting at 14 gestational weeks and repeated one hour after a meal at 28 gestational weeks. Women in group B were screened by 50 g GCT at 28 gestational weeks and followed by 75 g OGTT for those with abnormal 50 g GCT. The diagnostic effect of 50 g GCT for screening at different weeks of gestation with different ways was evaluated. Results (1)The rate of abnormal result of 50 g GCT was higher in fasting cases than that of cases testing after meal (15.6% vs 12.2%, P
4.On Establishing the Impelling Mode of Morality-Oriented Nursing Education
Chunhui LIU ; Mengshu WU ; Guirong YANG
Chinese Medical Ethics 1996;0(01):-
The impelling mode of morality-oriented nursing education unites moral affection and moral volition by impelling the need for nursing morality, and enables nurses to play an active role in the nursing work. This mode also indicates that nursing morality is a humanistic and valuable scientific career, and of great importance for guaranteeing the human wellbeing. Therefore, the establishment of morality-oriented nursing is a necessity for the specialization of nursing career.
5.Applicatim of high frequency sonography in laser treatment of children facial subcutaneous cavernous hemangiomas
Shousong XIE ; Meizhen WU ; Guirong LE
Chinese Journal of Ultrasonography 2001;10(2):106-108
Objective To apply high frequency ultrasound to laser treatment of children facial subcutaneous cavernous hemangiomas.Methods Ten children with facial subcutaneous hemangiomas were treated with Nd:YAG laser, the process was supervised with high frequency ultrasound.Results Before treatment,tumors showed low and inhomogenous echogenicity with blood flow signal;after treatment,the tumors appeared high and homogenous echogenicity with little or no blood flow signal. Conclusions The high frequency ultrasound is helpful for laser treatment of facial subcutaneous cavernous hemangiomas in preoperative location and postoperative assessment.
6.Clinical Observation of Bu Shen Tiao Qi Needling for Perimenopausal Syndrome
Guirong XIAO ; Kaiyang WANG ; Qun WU
Shanghai Journal of Acupuncture and Moxibustion 2017;36(2):157-161
Objective To observe the clinical efficacy of Bu Shen Tiao Qi(supplementing the kidney and regulating qi) needling in treating perimenopausal syndrome.Method Fifty patients were randomized into two groups, 25 cases each. The treatment group was intervened by Bu Shen Tiao Qineedling combined with electroacupuncture, while the control group was by shallow needling plus sham electroacupuncture. Kupperman Index (KI) wasobserved respectively before treatment, after 2-week and 4-week treatment, and in the 4-week follow-up study. The differences of scores and improvements of the 13 symptoms listed in KI were calculated.Result The total effective rate was 92.0% in the treatment group versus 44.0% in the control group; in the treatment group, the KI scores after 2-week treatment and in the 4-week follow-up study were significantly different from that before treatment (P<0.05), and a more significant difference was found after 4-week treatment (P<0.01); the between-group differences were statistically significant in comparing KI (P<0.05).Conclusion Bu Shen Tiao Qineedling can produce a satisfactory efficacy in treating perimenopausal syndrome.
7.Observations on the Therapeutic Effect of Liver-soothing and Spleen-reinforcing Acupuncture on Functional Constipation
Kaiyang WANG ; Guirong XIAO ; Qun WU
Shanghai Journal of Acupuncture and Moxibustion 2017;36(7):803-807
Objective To investigate the clinical efficacy of liver-soothing and spleen-reinforcing acupuncture in treating functional constipation.Methods Sixty patients with functional constipation were randomly allocated to treatment and control groups, 30 cases each. The treatment group received liver-soothing and spleen-reinforcing acupuncture and the control group, oral administration of prucalopride succinate tablets. The number of complete spontaneous bowel movements (CSBM), the number of spontaneous bowel movements (SBM), constipation symptoms (defecation time, defecatory difficulty and fecal characters) scores and The Patient Assessment of Constipation Quality of Life (PAC-QOL) score were recorded in the two groups before and after two and four weeks of treatment. The clinical therapeutic effects were compared.Results After two weeks of treatment, there were statistically significant pre-/post-treatment differences in CSBM and SBM in the treatment group (P<0.05) and significant post-treatment differences in CSBM and SBM between the two groups (P<0.05). After four weeks of treatment, there were statistically significant pre-/post-treatment differences in CSBM and SBM in the two groups (P<0.05) and no significant post-treatment differences in CSBM and SBM between the two groups (P>0.05). After two and four weeks of treatment, there were statistically significant pre-/post-treatment differences in constipation symptoms scores in thetwo groups (P<0.05). After two weeks of treatment, the defecation time and defecatory difficulty scores were significantly lower in the treatment group than in the control group; there were statistically significant differences between the two groups (P<0.05). After two and four weeks of treatment, the fecal character score was significantly higher in the control than in the treatment group; there was a statistically significant difference between the two groups (P<0.05). There were statistically significant pre-/post-treatment differences in the PAC-QOL scores in the two groups (P<0.05) and no significant post-treatment differences in the PAC-QOL scores between the two groups (P>0.05). The total efficacy rate was 80.0% in the treatment group and 73.3% in the control group; there was no statistically significant difference between the two groups (P>0.05).Conclusions Liver-soothing and spleen-reinforcing acupuncture has a marked therapeutic effect on functional constipation. It produces a quick effect with high safety.
8.Effects of Diazepam (Valium) Injected to Cervix During the Latent Phase of the First Stage of Labor
Xia WU ; Guirong ZHAI ; Xinghua HUANG
Chinese Journal of Perinatal Medicine 1998;0(03):-
Objective To observe the effects of diazepam on the cervix in relieving spasm, eliminating edema and improving dilation during the latent phase of labor. Methods One hundred normal parturients were randomly devided into study group ( n =50) and control group ( n =50). The study group was injected diazepam 10 mg in the cervix during the latent phase. The control group was given 10 mg of diazepam by intravenous injection. Results The dilating speed of cervix in study group was 2.81?1.92 cm/h. The mean time of the first stage of labor was 11.13?1.21 h, while the control group was 1.98?0.92 cm/h and 13.34?0.44 h respectively. The differences between two groups were statistically significant ( P
9.Predictive value of umbilical cord blood bilirubin level for neonatal pathological jaundice
Shanxia WU ; Siguo FENG ; Zhengshan CHEN ; Guirong WU ; Guanghui FANG
Chinese Journal of Postgraduates of Medicine 2011;34(15):21-22
Objective To investigate the predictive value of umbilical cord blood bilirubin for pathological jaundice in healthy term newborns. Methods Two ml navel string vein blood of baby were collected after giving birth in the normal newborn, and the hemobilirubin was detected by accidentally oxidation method. After birth, the infant's bilirubin level was tested on the forehead by the transcutaneous bilirubinometer at 8:00 -9:00 every morning until discharging from hospital. The ration of pathological jaundice of newborn and its treatment were analyzed in different levels of cord blood hemobilirubin. Results Fifty-nine cases ( 22.96% ) with pathological jaundice were diagnosed in 257 newboms.The concentration of cord blood hemobilirubin in baby with pathological jaundice [(39.68 ±8.10) μmol/L] was significantly higher than that of the normal newborn [(30.05 ±5.51) μmol/L](P<0.01). As the concentration of cord blood hemobilirubin was increased, the incidence of pathological jaundice was raised (P< 0.01), and the cases that needed to intervention treatment was increased(P< 0.01). Conclusion The detection of the level of cord blood hemobilirubin is not only very worthy to estimate the occurrence of pathological jaundice of newborn, but also offer reliable evidence for clinical early diagnosis and treatment.
10.Proper deployment of wounded and sick region on medical evacuation ship
Guirong WU ; Shiping XIANG ; Jiajin HONG ; Hanshen YE
Chinese Medical Equipment Journal 2003;0(10):-
Objective To explore how to reasonably deploy the wounded and sick region on the medical evacuation ship.Methods Three models of the wounded and sick region were set up according to different demand.Simulated exercises were imitated and medical staff and experts selected reasonable models.Results Most medical staff and experts selected the model which deployed the wounded and sick region according to whether the condition of an injury should be treated.Conclusion It is scientific and reasonable that the wounded and sick region is deployed according to whether the condition of an injury should be treated.