Objective:To observe the influence of electroacupuncture at Shu-points of the Five Zang-organ in domestic rabbits with acute allergy neuritis,a classical animal model,and to explore the immunoregulatory mechanism responsible for the regimen by detecting expression of the costimulatory molecules in sciatic nerve.Methods:ELISA was used to examine proteins of CD28,CTLA-4,B7-1,B7-2 in sciatic nerve of P2 immunized EAN domestic rabbits.Results:It was showed that the expression of CTLA-4 and B7-2 was obviously up-regulated(P

OBJECTIVE:To study the optimum conditions for extracting the effective components in Yansheng oral liquidMETHODS:Using orthogonal design L9(34),the content of total solid was taken as the screening indexInfluence of the concentration of alcohol on effective components was observedRESULTS:The number of times of extraction(D) had significant influence on the content of total solid(P

Acupuncture Points ; Acupuncture Therapy ; Female ; Hirschsprung Disease ; therapy ; Humans ; Infant

Objective To investigate the clinical efficacy of liver-soothing and spleen-reinforcing acupuncture in treating functional constipation.Methods Sixty patients with functional constipation were randomly allocated to treatment and control groups, 30 cases each. The treatment group received liver-soothing and spleen-reinforcing acupuncture and the control group, oral administration of prucalopride succinate tablets. The number of complete spontaneous bowel movements (CSBM), the number of spontaneous bowel movements (SBM), constipation symptoms (defecation time, defecatory difficulty and fecal characters) scores and The Patient Assessment of Constipation Quality of Life (PAC-QOL) score were recorded in the two groups before and after two and four weeks of treatment. The clinical therapeutic effects were compared.Results After two weeks of treatment, there were statistically significant pre-/post-treatment differences in CSBM and SBM in the treatment group (P<0.05) and significant post-treatment differences in CSBM and SBM between the two groups (P<0.05). After four weeks of treatment, there were statistically significant pre-/post-treatment differences in CSBM and SBM in the two groups (P<0.05) and no significant post-treatment differences in CSBM and SBM between the two groups (P>0.05). After two and four weeks of treatment, there were statistically significant pre-/post-treatment differences in constipation symptoms scores in thetwo groups (P<0.05). After two weeks of treatment, the defecation time and defecatory difficulty scores were significantly lower in the treatment group than in the control group; there were statistically significant differences between the two groups (P<0.05). After two and four weeks of treatment, the fecal character score was significantly higher in the control than in the treatment group; there was a statistically significant difference between the two groups (P<0.05). There were statistically significant pre-/post-treatment differences in the PAC-QOL scores in the two groups (P<0.05) and no significant post-treatment differences in the PAC-QOL scores between the two groups (P>0.05). The total efficacy rate was 80.0% in the treatment group and 73.3% in the control group; there was no statistically significant difference between the two groups (P>0.05).Conclusions Liver-soothing and spleen-reinforcing acupuncture has a marked therapeutic effect on functional constipation. It produces a quick effect with high safety.

Objective To observe the clinical efficacy of Bu Shen Tiao Qi(supplementing the kidney and regulating qi) needling in treating perimenopausal syndrome.Method Fifty patients were randomized into two groups, 25 cases each. The treatment group was intervened by Bu Shen Tiao Qineedling combined with electroacupuncture, while the control group was by shallow needling plus sham electroacupuncture. Kupperman Index (KI) wasobserved respectively before treatment, after 2-week and 4-week treatment, and in the 4-week follow-up study. The differences of scores and improvements of the 13 symptoms listed in KI were calculated.Result The total effective rate was 92.0% in the treatment group versus 44.0% in the control group; in the treatment group, the KI scores after 2-week treatment and in the 4-week follow-up study were significantly different from that before treatment (P<0.05), and a more significant difference was found after 4-week treatment (P<0.01); the between-group differences were statistically significant in comparing KI (P<0.05).Conclusion Bu Shen Tiao Qineedling can produce a satisfactory efficacy in treating perimenopausal syndrome.

Objective:To optimize the compatibility conditions of erigeron injection and study the stability after compatibility. Methods:An orthogonal test was employed using the quantity of insoluble particles and the content of rutin as the indices and tempera-ture, solvent and solvent amount as the influencing factors. The results were comprehensively analyzed. According to the results of the orthogonal test, three batches of samples were prepared and observed the stability in 24 hours, including the changes in the number of insoluble particles, pH and total flavonoid content. Results:The optimal compatibility conditions were as follows:the temperature was 25℃, and 250 ml 0. 9% sodium chloride injection was used as the solvent. The appearance and the insoluble particles showed no sig-nificant changes in 24 hours. The total flavonoid content was also stable in 4 hours, but decreased to some extent after then. Conclu-sion:At the clinical dose, erigeron injection in 250 ml 0. 9% sodium chloride injection can keep stable in 4 hours.

Objective To study the effect of sandalwood essential oil on isolated ileum smooth muscle of guinea pigs and the small intestine movement function of mice.Methods We used the experiment method of isolating ileum smooth muscle of guinea pigs and intestine propulsion of carbon ink in mice.We constructed the models of healthy mice,neostigminetrested mice and adrenaline-loaded mice.Results Sandalwood essential oil had an inhibitory effect on the spontaneous movement of guinea pigs isolated ileum and an antagonistic action on intestinal spasm caused by acetylcholine,histamine and barium chloride(P

Purpose To explore the ultrasonic characteristics of idiopathic retroperitoneal fibrosis (IRPF) and assess the diagnostic value of ultrasound. Materials and Methods Ultrasonic images of 11 cases of IRPF were retrospectively analyzed.Results The hypoechogenic masses encasing the abdominal aorta were detected in all cases, among which the encasement of inferior vena cava was found in 4 cases, the involvement of iliac artery in 3 cases and hydronephrosis in 9 cases.Conclusion IRPF demonstrated ultrasonic characteristics that would facilitate its detection and diagnosis.

Objective To examine the expression of CD8+CD28- T cells in the peripheral blood and explore their roles in the pathogenesis of AS. Methods The expression of CD8+CD28- T cells obtained from 50 AS patients and 21 healthy controls were assayed by flow cytometry. CRP was also measured. Results The percentage of peripheral blood CD8+CD28- T cells in patients with AS was significantly increased compared to normal individuals [(18±6)% vs (14±5)%, P=0.020], while the percentage of peripheral blood CD3+,CD8+ CD28+ T cells in patients with AS was significantly decreased[ (65±9)% vs (69±8)%, P=0.039]; [ (15±5)% vs(18±4)%, P=0.038]. No difference was found in CD8+ T cells between patients with AS and normal individuals(P＞0.05). Conclusion The percentage of peripheral blood CD8+CD28- T cells in patients with AS is significantly increased comparing to normal individuals. This suggests that CD8+CD28- T cells may play an important role in the pathogenesis of AS.

Objective: To measure the fracture strength of the posterior galvano-ceramic bridges made by Ni-Cr pontic fired bonding galvano caps with highly temperature-resistant adhesive and to provide re-ference data for clinical application. Methods: A standard low dental cast was achieved with 46 missing. Five posterior galvano-ceramic bridges made by Ni-Cr pontic fired bonding galvano caps, with abutments being 47 and 45 . The low dental cast was fixed on the panel of the universal testing machine, vertical load given on the central of the pontic as the velocity of 2 mm/min. Results: The fracture strength of the posterior galvano-ceramic bridges made by Ni-Cr pontic fired bonding galvano caps was (877.00?126.53) N, the fracture strength of the metal frame was (1 448.94?51.02) N. Conclusion: Posterior galvano-ceramic bridges made by Ni-Cr pontic fired bonding galvano caps could endure the normal human occlusal force.