S.I. of TCSA PCH (group B) and musk ambrette PCH (group D) were respectively g3 49% and 75.00 S.I. of group A and B, which were only challenged with TCSA and musk ambrette respectively without prior sensitization, were 33, 33% and 27. 78%. These data indicated the TCSA PCH (group B) was experimentally produced in guinea pigs when it compared to musk ambrette PCH (group D) and controls (group A and C) (Table 1). However, S.I. of TCSA PCH was somewhat lower than index of musk ambrette PCH.
Animals ; Guinea Pigs* ; Guinea* ; Hypersensitivity*

No abstract available.
Animals ; Dinitrochlorobenzene* ; Guinea Pigs* ; Guinea*

No abstract available.
Anesthesia* ; Animals ; Guinea Pigs* ; Guinea*

No abstract available.
Animals ; Guinea Pigs* ; Guinea* ; Perilymph*

The current experiment pursued the time course of UVB-induced immune suppression of DNCB contact hypersensitivity(CHS) in guinea pigs. Both group B and C, received suberythemal doses of UVB on days -3, -2, -1, 0 and -6, -5, -4, 3 respectively, showed marked suppressions of CHS (56.36p;and56.25p,). However, the recovery of CHS from the UVB-induced suppression started by group D(UVB on days -9, -8, -7, -6: 67. 36%) and further extended to subsequent group E(UVB on days -12, -11, -10, -9: 78.82%), Group F(UVB on days -15, -14, -13, -12: 79.86%) and the final group G(UVB on days -18, -17, -16, -15: 81. 94%) in which the recovery of CHS slightly exceeded the control (group A:79. 86%).
Animals ; Dermatitis, Contact* ; Dinitrochlorobenzene* ; Guinea Pigs* ; Guinea*

No abstract available.
Animals ; Dermatitis, Contact* ; Guinea Pigs* ; Guinea* ; Spleen*

No abstract available.
Animals ; Guinea Pigs* ; Guinea* ; Langerhans Cells*

No abstract available.
Animals ; Guinea Pigs* ; Guinea* ; Papaverine* ; Skin* ; Triamcinolone*

No abstract available.
Animals ; Dermatitis* ; Guinea Pigs* ; Guinea* ; Malassezia*

The aims of study presented here were to determine dose-dependent effects of UVB irradiation on CHS reaction and comparative effects of VVB on the induction and elicitation in guinea pigs. Pre-induction exposure to either suberythemal or supraerythemal doses of UVB resulted in suppreasion of CHS (53.47% & 57.64%) campared to positive control (79. 86%) However, suberythemal doses of UVB generated a more potent suppression than supraerythemal doses. Pre-elicitation exposure to suberythemal doses of UVB on the elicitation sites and adjacent to elicitation sites resulted in suppressed CHS reactions in both groups (60.4zg & 56.25p,). When the reaction by UVB was eliminated from the cutaneous reaction elicited in guinea pigs sensitized to DNCB, by UVB irradiation on the adjacent to elicitation sites, generated a more potent suppression than that UVB was directly irradiated on the elicitation sites.
Animals ; Dermatitis, Contact* ; Dinitrochlorobenzene* ; Guinea Pigs* ; Guinea*