1.Older Adult Patients in the Emergency Department: Which Patients should be Selected for a Different Approach?
Nere Larrea AGUIRRE ; Susana García GUTIÉRREZ ; Oscar MIRO ; Sira AGUILÓ ; Javier JACOB ; Aitor ALQUÉZAR-ARBÉ ; Guillermo BURILLO ; Cesáreo FERNANDEZ ; Pere LLORENS ; Cesar Roza ALONSO ; Ivana Tavasci LOPEZ ; Mónica CAÑETE ; Pedro Ruiz ASENSIO ; Beatriz Paderne DÍAZ ; Teresa Pablos PIZARRO ; Rigoberto Jesús del Rio NAVARRO ; Núria Perelló VIOLA ; Lourdes HERNÁNDEZ-CASTELLS ; Alejandro Cortés SOLER ; Elena SÁNCHEZ FERNÁNDEZ-LINARES ; Jesús Ángel Sánchez SERRANO ; Patxi EZPONDA ; Andrea Martínez LORENZO ; Juan Vicente Ortega LIARTE ; Susana Sánchez RAMÓN ; Asumpta Ruiz ARANDA ; Francisco Javier MARTÍN-SÁNCHEZ ; Juan González DEL CASTILLO ;
Annals of Geriatric Medicine and Research 2024;28(1):9-19
Background:
While multidimensional and interdisciplinary assessment of older adult patients improves their short-term outcomes after evaluation in the emergency department (ED), this assessment is time-consuming and ill-suited for the busy environment. Thus, identifying patients who will benefit from this strategy is challenging. Therefore, this study aimed to identify older adult patients suitable for a different ED approach as well as independent variables associated with poor short-term clinical outcomes.
Methods:
We included all patients ≥65 years attending 52 EDs in Spain over 7 days. Sociodemographic, comorbidity, and baseline functional status data were collected. The outcomes were 30-day mortality, re-presentation, hospital readmission, and the composite of all outcomes.
Results:
During the study among 96,014 patients evaluated in the ED, we included 23,338 patients ≥65 years—mean age, 78.4±8.1 years; 12,626 (54.1%) women. During follow-up, 5,776 patients (24.75%) had poor outcomes after evaluation in the ED: 1,140 (4.88%) died, 4,640 (20.51) returned to the ED, and 1,739 (7.69%) were readmitted 30 days after discharge following the index visit. A model including male sex, age ≥75 years, arrival by ambulance, Charlson Comorbidity Index ≥3, and functional impairment had a C-index of 0.81 (95% confidence interval, 0.80–0.82) for 30-day mortality.
Conclusion
Male sex, age ≥75 years, arrival by ambulance, functional impairment, or severe comorbidity are features of patients who could benefit from approaches in the ED different from the common triage to improve the poor short-term outcomes of this population.
2.Older Adult Patients in the Emergency Department: Which Patients should be Selected for a Different Approach?
Nere Larrea AGUIRRE ; Susana García GUTIÉRREZ ; Oscar MIRO ; Sira AGUILÓ ; Javier JACOB ; Aitor ALQUÉZAR-ARBÉ ; Guillermo BURILLO ; Cesáreo FERNANDEZ ; Pere LLORENS ; Cesar Roza ALONSO ; Ivana Tavasci LOPEZ ; Mónica CAÑETE ; Pedro Ruiz ASENSIO ; Beatriz Paderne DÍAZ ; Teresa Pablos PIZARRO ; Rigoberto Jesús del Rio NAVARRO ; Núria Perelló VIOLA ; Lourdes HERNÁNDEZ-CASTELLS ; Alejandro Cortés SOLER ; Elena SÁNCHEZ FERNÁNDEZ-LINARES ; Jesús Ángel Sánchez SERRANO ; Patxi EZPONDA ; Andrea Martínez LORENZO ; Juan Vicente Ortega LIARTE ; Susana Sánchez RAMÓN ; Asumpta Ruiz ARANDA ; Francisco Javier MARTÍN-SÁNCHEZ ; Juan González DEL CASTILLO ;
Annals of Geriatric Medicine and Research 2024;28(1):9-19
Background:
While multidimensional and interdisciplinary assessment of older adult patients improves their short-term outcomes after evaluation in the emergency department (ED), this assessment is time-consuming and ill-suited for the busy environment. Thus, identifying patients who will benefit from this strategy is challenging. Therefore, this study aimed to identify older adult patients suitable for a different ED approach as well as independent variables associated with poor short-term clinical outcomes.
Methods:
We included all patients ≥65 years attending 52 EDs in Spain over 7 days. Sociodemographic, comorbidity, and baseline functional status data were collected. The outcomes were 30-day mortality, re-presentation, hospital readmission, and the composite of all outcomes.
Results:
During the study among 96,014 patients evaluated in the ED, we included 23,338 patients ≥65 years—mean age, 78.4±8.1 years; 12,626 (54.1%) women. During follow-up, 5,776 patients (24.75%) had poor outcomes after evaluation in the ED: 1,140 (4.88%) died, 4,640 (20.51) returned to the ED, and 1,739 (7.69%) were readmitted 30 days after discharge following the index visit. A model including male sex, age ≥75 years, arrival by ambulance, Charlson Comorbidity Index ≥3, and functional impairment had a C-index of 0.81 (95% confidence interval, 0.80–0.82) for 30-day mortality.
Conclusion
Male sex, age ≥75 years, arrival by ambulance, functional impairment, or severe comorbidity are features of patients who could benefit from approaches in the ED different from the common triage to improve the poor short-term outcomes of this population.
3.Older Adult Patients in the Emergency Department: Which Patients should be Selected for a Different Approach?
Nere Larrea AGUIRRE ; Susana García GUTIÉRREZ ; Oscar MIRO ; Sira AGUILÓ ; Javier JACOB ; Aitor ALQUÉZAR-ARBÉ ; Guillermo BURILLO ; Cesáreo FERNANDEZ ; Pere LLORENS ; Cesar Roza ALONSO ; Ivana Tavasci LOPEZ ; Mónica CAÑETE ; Pedro Ruiz ASENSIO ; Beatriz Paderne DÍAZ ; Teresa Pablos PIZARRO ; Rigoberto Jesús del Rio NAVARRO ; Núria Perelló VIOLA ; Lourdes HERNÁNDEZ-CASTELLS ; Alejandro Cortés SOLER ; Elena SÁNCHEZ FERNÁNDEZ-LINARES ; Jesús Ángel Sánchez SERRANO ; Patxi EZPONDA ; Andrea Martínez LORENZO ; Juan Vicente Ortega LIARTE ; Susana Sánchez RAMÓN ; Asumpta Ruiz ARANDA ; Francisco Javier MARTÍN-SÁNCHEZ ; Juan González DEL CASTILLO ;
Annals of Geriatric Medicine and Research 2024;28(1):9-19
Background:
While multidimensional and interdisciplinary assessment of older adult patients improves their short-term outcomes after evaluation in the emergency department (ED), this assessment is time-consuming and ill-suited for the busy environment. Thus, identifying patients who will benefit from this strategy is challenging. Therefore, this study aimed to identify older adult patients suitable for a different ED approach as well as independent variables associated with poor short-term clinical outcomes.
Methods:
We included all patients ≥65 years attending 52 EDs in Spain over 7 days. Sociodemographic, comorbidity, and baseline functional status data were collected. The outcomes were 30-day mortality, re-presentation, hospital readmission, and the composite of all outcomes.
Results:
During the study among 96,014 patients evaluated in the ED, we included 23,338 patients ≥65 years—mean age, 78.4±8.1 years; 12,626 (54.1%) women. During follow-up, 5,776 patients (24.75%) had poor outcomes after evaluation in the ED: 1,140 (4.88%) died, 4,640 (20.51) returned to the ED, and 1,739 (7.69%) were readmitted 30 days after discharge following the index visit. A model including male sex, age ≥75 years, arrival by ambulance, Charlson Comorbidity Index ≥3, and functional impairment had a C-index of 0.81 (95% confidence interval, 0.80–0.82) for 30-day mortality.
Conclusion
Male sex, age ≥75 years, arrival by ambulance, functional impairment, or severe comorbidity are features of patients who could benefit from approaches in the ED different from the common triage to improve the poor short-term outcomes of this population.
4.Clinical and Safety Outcomes of Endovascular Therapy 6 to 24 Hours After Large Vessel Occlusion Ischemic Stroke With Tandem Lesions
Milagros GALECIO-CASTILLO ; Mudassir FAROOQUI ; Ameer E. HASSAN ; Mouhammad A. JUMAA ; Afshin A. DIVANI ; Marc RIBO ; Michael ABRAHAM ; Nils H. PETERSEN ; Johanna T. FIFI ; Waldo R. GUERRERO ; Amer M. MALIK ; James E. SIEGLER ; Thanh N. NGUYEN ; Sunil SHETH ; Albert J. YOO ; Guillermo LINARES ; Nazli JANJUA ; Darko QUISPE-OROZCO ; Wondwossen TEKLE ; Syed F. ZAIDI ; Sara Y. SABBAGH ; Marta OLIVÉ-GADEA ; Tiffany BARKLEY ; Reade De LEACY ; Kenyon W. SPRANKLE ; Mohamad ABDALKADER ; Sergio SALAZAR-MARIONI ; Jazba SOOMRO ; Weston GORDON ; Charoskhon TURABOVA ; Juan VIVANCO-SUAREZ ; Aaron RODRIGUEZ-CALIENES ; Maxim MOKIN ; Dileep R. YAVAGAL ; Tudor JOVIN ; Santiago ORTEGA-GUTIERREZ
Journal of Stroke 2023;25(3):378-387
Background:
and Purpose Effect of endovascular therapy (EVT) in acute large vessel occlusion (LVO) patients with tandem lesions (TLs) within 6–24 hours after last known well (LKW) remains unclear. We evaluated the clinical and safety outcomes among TL-LVO patients treated within 6–24 hours.
Methods:
This multicenter cohort was divided into two groups, based on LKW to puncture time: early window (<6 hours), and late window (6–24 hours). Primary clinical and safety outcomes were 90-day functional independence measured by the modified Rankin Scale (mRS: 0–2) and symptomatic intracranial hemorrhage (sICH). Secondary outcomes were successful reperfusion (modified Thrombolysis in Cerebral Infarction score ≥2b), first-pass effect, early neurological improvement, ordinal mRS, and in-hospital and 90-day mortality.
Results:
Of 579 patients (median age 68, 32.1% females), 268 (46.3%) were treated in the late window and 311 (53.7%) in the early window. Late window group had lower median National Institutes of Health Stroke Scale score at admission, Alberta Stroke Program Early Computed Tomography Score, rates of intravenous thrombolysis, and higher rates for perfusion imaging. After adjusting for confounders, the odds of 90-day mRS 0–2 (47.7% vs. 45.0%, adjusted odds ratio [aOR] 0.71, 95% confidence interval [CI] 0.49–1.02), favorable shift in mRS (aOR 0.88, 95% CI 0.44–1.76), and sICH (3.7% vs. 5.2%, aOR 0.56, 95% CI 0.20–1.56) were similar in both groups. There was no difference in secondary outcomes. Increased time from LKW to puncture did not predicted the probability of 90-day mRS 0–2 (aOR 0.99, 95% CI 0.96–1.01, for each hour delay) among patients presenting <24 hours.
Conclusion
EVT for acute TL-LVO treated within 6–24 hours after LKW was associated with similar rates of clinical and safety outcomes, compared to patients treated within 6 hours.
5.Older Adult Patients in the Emergency Department: Which Patients should be Selected for a Different Approach?
Nere Larrea AGUIRRE ; Susana García GUTIÉRREZ ; Oscar MIRO ; Sira AGUILÓ ; Javier JACOB ; Aitor ALQUÉZAR-ARBÉ ; Guillermo BURILLO ; Cesáreo FERNANDEZ ; Pere LLORENS ; Cesar Roza ALONSO ; Ivana Tavasci LOPEZ ; Mónica CAÑETE ; Pedro Ruiz ASENSIO ; Beatriz Paderne DÍAZ ; Teresa Pablos PIZARRO ; Rigoberto Jesús del Rio NAVARRO ; Núria Perelló VIOLA ; Lourdes HERNÁNDEZ-CASTELLS ; Alejandro Cortés SOLER ; Elena SÁNCHEZ FERNÁNDEZ-LINARES ; Jesús Ángel Sánchez SERRANO ; Patxi EZPONDA ; Andrea Martínez LORENZO ; Juan Vicente Ortega LIARTE ; Susana Sánchez RAMÓN ; Asumpta Ruiz ARANDA ; Francisco Javier MARTÍN-SÁNCHEZ ; Juan González DEL CASTILLO ;
Annals of Geriatric Medicine and Research 2024;28(1):9-19
Background:
While multidimensional and interdisciplinary assessment of older adult patients improves their short-term outcomes after evaluation in the emergency department (ED), this assessment is time-consuming and ill-suited for the busy environment. Thus, identifying patients who will benefit from this strategy is challenging. Therefore, this study aimed to identify older adult patients suitable for a different ED approach as well as independent variables associated with poor short-term clinical outcomes.
Methods:
We included all patients ≥65 years attending 52 EDs in Spain over 7 days. Sociodemographic, comorbidity, and baseline functional status data were collected. The outcomes were 30-day mortality, re-presentation, hospital readmission, and the composite of all outcomes.
Results:
During the study among 96,014 patients evaluated in the ED, we included 23,338 patients ≥65 years—mean age, 78.4±8.1 years; 12,626 (54.1%) women. During follow-up, 5,776 patients (24.75%) had poor outcomes after evaluation in the ED: 1,140 (4.88%) died, 4,640 (20.51) returned to the ED, and 1,739 (7.69%) were readmitted 30 days after discharge following the index visit. A model including male sex, age ≥75 years, arrival by ambulance, Charlson Comorbidity Index ≥3, and functional impairment had a C-index of 0.81 (95% confidence interval, 0.80–0.82) for 30-day mortality.
Conclusion
Male sex, age ≥75 years, arrival by ambulance, functional impairment, or severe comorbidity are features of patients who could benefit from approaches in the ED different from the common triage to improve the poor short-term outcomes of this population.