1.Mechanism simulation of blood cell velocity measurement by Doppler ultrasonic blood equipment
Chinese Medical Equipment Journal 2004;0(09):-
VB programme and flash technique are used to visually display physical mechanism of blood cell velocity measurement in vein taken by Doppler ultrasonic blood equipment.
2.Role of probiotics against the infection of parasites in the intestine
Chinese Journal of Zoonoses 2017;33(5):459-464
Probiotics have been defined as living microorganisms exert beneficial effects on the health of the host,which can be effective in the treatment of gastrointestinal tract,respiratory tract infections and allergic diseases.Although it is currently mainly used for the treatment of bacterial and viral infections,there are also studies have shown that probiotics have inhibitory effects on parasites infection.Therefore,probiotics will provide a new way for the prevention and treatment of parasites.
3.Discussion of Inflexion Question in Course of Measuring Surface Tension Coefficient by Force Sensor
Chinese Medical Equipment Journal 1989;0(01):-
Objective To discuss the inflexion question in the course of measuring surface tension coefficient.Methods Metal frames with different lengths,radials and metal cylinders with different inside & outside radials were used to measure the inflexion.Results The inflexion appeared in the course of measuring surface tension coefficient by using force sensor and the inflexion changed with the different radials and lengths of the metal frames.Conclusion The thickness and bending of the fluid membrane results in the change of inflexion,and the inflexion can be avoided with the length and radial chosen properly.
4.Health risk warning system and its follow up results
Guilian WANG ; Zhiheng CHEN ; Nana TAN
Chinese Journal of Health Management 2014;8(2):95-98
Objective To explore the reporting process of our health risk warning system and its long-term effectiveness.Methods A total of 1 168 individuals who were identified as higher risk populations from July 2011 to June 2012 in our Health Mangement Center were served as the control group,and another 973 adults who were identified as higher risk individuals from July 2012 to May 2013 were assigned to the study group.Diagnosis and treatment were based on our health risk reporting process and follow-up system.Paired t test and paired contingency table x2 test were used for data analysis.Results The rate of follow-up (97% vs 100%,x2=30.503,P<0.05),consultation (83.48% vs 93.63%,x2=52.142,P< 0.05),mean treatment time ((3.0±0.5) vs (1.5±0.5) d,t=69.12,P<0.05) and patient satisfaction (87.84% vs 96.20%,x2=48.361,P<0.05) were significantly different between the two groups,although no statistically significant difference of incidence of adverse events was found (0.26% vs 0.10%,x2 =0.102,P>0.05).Conclusion Our health risk warning system may reduce the time for physical examination and improve disease diagnosis level and patients' satisfaction.Moreover,our health manatement system and health service quality should further be improved in practice.
5.Edge detection of medical image and methods for tracking & showing of gray level in special regions
Liping GE ; Cuizhen BAI ; Tieli LIU ; Li WANG ; Guilian WANG
Chinese Medical Equipment Journal 2003;0(11):-
By using the image processing function and programming tomography,the following functions are realized: the contour line,edge line and gradation histogram of medical images are displayed;the selected regions of medical images are freely zoomed;the gray level of discretional regions is displayed using medical image processing tool and the distance of the given points is freely measured.
6.Current status of hyper-triglyceridemia in community residents of Beijing
Guilian WANG ; Yihong SUN ; Yuanyuan FU ; Dayi HU
Chinese Journal of General Practitioners 2009;8(7):443-447
Objective To investigate blood level of triglyceride(TG)in community residents of urban and rural Beijing.Methods A total of 10 054 community residents were recruited by cluster samphng for investigation using questionnaire,as well as physical examinations and fasting plasma TG determination for diagnosing hypertriglyceridemia,during June to August,2007.Results Median of plasma level of TG of the participants was 1.17 mmol/L,ranging(0.81-1.78)mmoVL Totally,1234 people were diagnosed as borderline hypertriglyceridemia and 15 12 as hypertriglycefidemia.with prevalence of 12.27%and 15.04%,respectively.There was no significant difference in plasma level ofTG between men andwomen[1.16(0.80-1.84)mmol/L vs.1.18(0.81-1.75)mmol/L,P:0.187].Age-adjusted prevalence of borderline hypertriglyceridemia and hypertriglyeeridemia was higher in men than those in women(11.60% vs.10.90%and 20.32% vs.10.88%,respectively),and the same results were obrained in those less than 50 years old,however,reveraw outcomes were got in those more than 50 years old.Plasma level of TG,as well as prevalence of hypertriglyceridemia,were higher in those living in urban areas than those in rural areas[1.31(0.89-1.95)mmol/L vs.1.05(0.73-1.58)mmol/L].Awareness,proportion of people with hyperglycefidemia under treatment and proportion of those with TG under coutrol were 13.95%.35.92%and 38.51%,respectively.Standardized prevalence of borderline hyperglycefidemia and hyperglycefidemia were higher in those with coronary heart disease than those without it(24.79% vs.11.22%and 25.31% vs.15.35%,respectively).Conclusions Awareness,proportion of treatment and proportion of those under control for hyperglyceridemia were all lower in community residents of Beijing.Education and monitoring on hyperglyeeridemia should especially be strengthened for urban residents,women aged more than 50 years,and these with coronary heart disease.
7.Research Progress of Study on Function of T Cell Immunity against Influenza Virus.
Wentao YANG ; Shaohua SHI ; Guilian YANG ; Chunfeng WANG
Chinese Journal of Virology 2015;31(4):440-449
The influenza A virus (IAV) belongs to the family Influenza Virus and subfamily Orthomyxoviridae. The IAV can cause acute infections of the lower respiratory in human and animals. Recently, many studies have been performed to reveal the lung CD4+ T cells, CD8+ T cells and Tregs via multiple effector and regulatory mechanisms to against IAV. In this paper, we review the state of progress with regards to various strategies of IAV escape from T cell responses, T cells and innate T cells immunity against influenza virus, which will provide a useful reference tool for future related reseach.
Animals
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Humans
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Influenza A virus
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immunology
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physiology
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Lung
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immunology
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virology
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T-Lymphocytes
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immunology
8.A Clinical Study of 46 Children with Cyclic Vomiting Syndrome
Guilian SUN ; Yajing JIANG ; Lin JIANG ; Dongying WANG ; Zhiliang YANG
Journal of China Medical University 2010;(1):67-70
Objective To analyze the clinical characteristics of children with cyclic vomiting syndrome (CVS), summarize the clinical experience, and improve the awareness,diagnosis and treatment level of CVS.Methods The clinical data and results of long-term follow-up of the children with CVS were collected and analyzed from 1995 to 2009 in our department.Results Forty-six children were enrolled in the study, including 22 boys and 24 girls.Mean onset age was 4.5 years(ranged from 1 to 11 years)and the mean age at final diagnosis was 8.5 years (ranged from 4.5 to 14.5 years).Sixty-six and seventy-four percent of patients had family history of migraine and motional sickness respectively,whereas 83% patients had triggers.The clinical manifestation of CVS was severe episodic vomiting.The episodes had a rapid onset and sudden ending,persisted for several hours to days,and were separated by symptom-free intervals.The incidental symptoms were pallor, lethargy,intractable nausea,abdominal pain,headache,photophobia and dizzy.Twenty-nine patients diagnosed were followed up for 5 years at average.Five patients were treated with valproate,4 with cyproheptadine, 5 with cyproheptadine and valproate,5 with amitriptyline,cyprohep tadine and valproate,and 3 with cyproheptadine and flunarizine.All treated patients recovered mean 10 months(1.5 months to 2 years) years later and displayed the reduced number of episodes or the severity of episodes except 3 patients.Twenty-eight percent (8/29) of patients progressed to migraine headaches.Conclusion CVS is a relatively common disease in children and awareness of the condition should be increased.CVS should be considered when patients had recurrent vomitting and were completely healthy between the two episodes after excluding other pathological conditions.
9.Pulmonary Cryptococcosis and Its Clinical Feature Analysis
Jian CHEN ; Guilian LI ; Ligong NIE ; Guangfa WANG
Chinese Journal of Nosocomiology 2005;0(11):-
OBJECTIVE To explore the clinical features for pulmonary cryptococcosis due to Cryptococcus neoformans,and to improve diagnosis and treatment of the disease.METHODS The clinical features of inpatients with pulmonary cryptococcosis were studied retrospectively.RESULTS There were nine cases of pulmonary cryptococcosis from 1999 to 2006 of all inpatients in our hospital.Mals 5(56%),females 4(44%),and 3 cases(33%) were more than 60 years old.Three cases(33%) were immunocompromised hosts,6 cases(67%) had clinical symptoms.Chest X-ray and computed tomography were various included single or poly patching or nodule shadows,some had cavity(33%) and some had pleural effusions(22%).Six cases had positive results with serum cryptococcal antigen test.All nine patients were treated with fluconazole and improved or cured.CONCLUSIONS Pulmonary cryptococcosis is seldom seen in clinic,it can be observed in humans with normal immune responses or immunocompromised hosts and has no significant clinic manifestations,serum cryptococcal antigen test is helpful,definitive diagnosis needs early lung biopsy.The therapeutic effect is well.
10.The effect of juvenile rheumatoid arthritis serum on the LTB4-BLT2 signal pathway of mice dendritic cells
Yang YANG ; Xinsheng CHEN ; Fanqing TIAN ; Guilian SHANG ; Hongwei WANG
Chinese Journal of Rheumatology 2008;12(6):379-381,插2
Objective To investigate the effect of iuvenile rheumatoid arthritis(JRA) serum (leukotriene B4,LTB4) LTB4-BLT2 on mice DCs.Methods Bone marrow(BM)-derived DCs from healthy mouse were purified.and induced by cytokine IL-4 and GM-CSF to immature DCs and then differentiated to mature DCs under the stimulation of LPS in vitro.DCs were evaluated by light microscope and flow cvtometry.The concentrations of LTB4 in DCs supernatant,normal serum,active JRA,and that of the co-cuItured with BLT2 antagonist LY255283 were detected by ELISA.The expression of BLT2 protein and mRNA in DCs was examined by immunocytochemistry,immunofluorescence and RT-PCR.Meanwhile,the expression of BLT2 in DCs after 18 h co-cultured with normal serum,in serum of active JRA and that of BLT2 antagonist (LY255283)group was assayed by flow cytometry respectively.Results LTB4-BLT2 was expressed by DCs.Not only BLT2 mRNA but also its protein was expressed in DCs.The concentration of LTB4 Was(17±3)pg/ml,(82±20)pg/ml,(82±20)pg/ml and(24±6)pg/ml,(115±20)pg/ml,(91±11)pg/ml in normal serum group,active JRA group and LY255283 group before and after 1 8 h,respectively.The expression Was higher in serum of active JRA group than that of normal sertlm group(P<0.01)and there was a tendency to be higher when compared with LY255283 group(P<0.05).The DC BLT2 expression was 27.7±2.9,46.3±8.7 and 30.3±5.5 in normal serum group,serum of active JRA group and LY255283 grbup after 1 8h respectively.The expression was stronger in active JRA group than other groups(P<0.05).Conclusion DC can develop a LTB4-BLT2 signal pathway by BLT2 with autocrine and/or extrinsic LTB4.The overexpression of this pathway may be involved in the initiating and activation of JRA.