Objective The present study was aimed to promote the informatization process of scientific research contract and enhance the management level and quality of hospital contract.Methods Legal risks existing in traditional contract management mode in a 3A grade hospital in Shanghai,were taken as an example for exploration on how to reduce and avoid the legal risks by using modern information technology.Results There were many problems in the traditional contract management mode,its main representations were:low efficiency,difficult to supervise,hard to be shared,and the risk of not-fixed content.On the contrary,modern information technology has the following merits,such as:reducing the legal risk caused by human factors,the full control of the contract,shared information,decreased risk,consistent data,and fair approval.Conclusions Modern information technology will be helpful to control risks in the whole process of scientific research contract,and refine the management of scientific research contract.

Objective To investigate the gastric contents reflux occurred in the patients in Neurosurgery Intensive Care Unit ( NICU) , and to analyze the risk factors of gastric contents reflux and provide basis for timely and effective nursing intervention measures of clinical practice. Methods A total of 47 patients with mechanical ventilation in NICU of some grade A class three hospitals were collected the data such as age, gender, body posture, state of consciousness, gastric retention, diameter of nasogastric tube, the ballonet pressure of artifical airway and also included samples of throat secretion to test pepsin and pH. Results A total of 235 times watched among 47 patients that the incidence rate of gastric contents reflux was 48. 1%. The single factor analysis showed that there were significant differences of gastric contents reflux between subgroups of different tube diameter, nasal feeding pump rate, gastric retention, Glasgow score and ballonet pressure (χ2 =6. 641, 56. 615, 142. 846, 17. 784, 8. 620;P<0. 05). Further logistic regression analysis indicated that the factors affected gastric contents reflux was nasal feeding pumping rate and gastric retention. Conclusions Gastric contents reflux is a common complication in EN patients in the NICU. According to the Influencing factors, monitoring gastric retention and set proper nasal feeding pump rate is important for continuous nasal feeding patients to reduce gastric contents reflux rate.